Nasal administration of recombinant osteopontin attenuates early brain injury after subarachnoid hemorrhage

Stroke

Volumn 44, Issue 11, 2013, Pages 3189-3194

  Topkoru, Basak Caner ^a   Altay, Orhan ^a   Duris, Kamil ^a   Krafft, Paul R ^a   Yan, Junhao ^a   Zhang, John H ^a,b  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOMA LINDA UNIVERSITY   (United States)

Author keywords

Administration; Apoptosis; Early brain injury; Intranasal; Recombinant osteopontin; Subarachnoid hemorrhage

Indexed keywords

CASPASE 3; FOCAL ADHESION KINASE; FOCAL ADHESION KINASE INHIBITOR; MOUSE ROPN HIS TAGGED; OSTEOPONTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RECOMBINANT OSTEOPONTIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CELL; BRAIN CORTEX; BRAIN EDEMA; BRAIN INJURY; BRAIN WATER; CELL DEATH; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID LEVEL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LEFT HEMISPHERE; MALE; MORTALITY; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRIFORM CORTEX; RAT; RIGHT HEMISPHERE; SHAM PROCEDURE; SUBARACHNOID HEMORRHAGE; WATER CONTENT; WESTERN BLOTTING;

ADMINISTRATION, INTRANASAL; APOPTOSIS; EARLY BRAIN INJURY; RECOMBINANT OSTEOPONTIN; SUBARACHNOID HEMORRHAGE;

ADMINISTRATION, INTRANASAL; ANIMALS; APOPTOSIS; BRAIN; BRAIN INJURIES; CASPASE 3; FOCAL ADHESION KINASE 1; MALE; NEURONS; OSTEOPONTIN; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SUBARACHNOID HEMORRHAGE; TIME FACTORS;

EID: 84888305662     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.113.001574     Document Type: Article

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