Lead exposure and intelligence in 7-year-old children: The Yugoslavia Prospective Study

Environmental Health Perspectives

Volumn 105, Issue 9, 1997, Pages 956-962

  Wasserman, Gail A ^a,b,c   Liu, Xinhua ^b   Lolacono, Nancy J ^c   Factor Litvak, Pam ^c   Kline, Jennie K ^b,c,d   Popovac, Dusan ^e   Morina, Nada ^e   Musabegovic, Aida ^c   Vrenezi, Nait ^e   Capuni Paracka, Sabahate ^f   Lekic, Vojkan ^f   Preteni Redjepi, Emine ^f   Hadzialjevic, Suzana ^f   Slavkovich, Vesna ^c   Graziano, Joseph H ^c  

^a Columbia University ^*  (United States)

^b NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

^e UNIVERSITY OF PRI TINA   (Serbia)

^f Columbia University/NYSPI ^*

Author keywords

Child development; Intelligence; Lead; Perceptual motor functioning; WISC III

Indexed keywords

LEAD;

ARTICLE; BIRTH WEIGHT; CHILD; CHILD DEVELOPMENT; DEMOGRAPHY; EDUCATION; ENVIRONMENTAL EXPOSURE; ETHNOLOGY; GENDER; HUMAN; INTELLIGENCE; INTELLIGENCE TEST; LEAD BLOOD LEVEL; MATERNAL AGE; MOTOR PERFORMANCE; NORMAL HUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; SIBLING; SMELTER; TASK PERFORMANCE; TOXICOKINETICS; YUGOSLAVIA;

EID: 0030733182     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.97105956     Document Type: Article

References (42)

1. Wasserman GA, Graziano JH, Factor-Litvak P, Popovac D, Morina N, Musabegovic A, Vrenzi N, Campani-Paracka S, Lekic V, Preteni-Redjepi E. Consequences of lead exposure and iron supplementarion on childhood development at age four years. Neurotoxicol Teratol 16:233-240 (1994).
2. Wasserman GA, Graziano JH, Factor-Litvak P, Popovac D, Morina N, Musabegovic A, Vrenzi N, Campani-Paracka S, Lekic V, Preteni-Redjepi E. Independent effects of lead exposure and iron deficiency anemia on developmental outcome at age 2 years. J Pediatr 121:695-703 (1992).
3. Bellinger D, Leviton A, Needleman HL, Waternaux C, Rabinowitz M. Low-level lead exposure and infant development in the first year. Neurobehav Toxicol Teratol 8:151-161 (1986).
4. Bellinger D, Needleman HL, Leviton A, Waternaux C, Rabinowitz M, Nichols ML. Early sensory-motor development and prenatal exposure to lead. Neurobehav Toxicol Teratol 6:387-402 (1984).
5. Baghurst PA, McMichael AJ, Wigg NR, Vimpani GV, Robertson EF, Roberts RJ, Tong SL. Environmental exposure to lead and children's intelligence at the age of seven years. The Port Pirie Cohort Study. N Engl J Med 327:1279-1284 (1992).
6. McMichael AJ, Baghurst PA, Vimpani GV, Wigg NR, Robertson EF, Tong S. Tooth lead levels and IQ in school-age children: the Port Pirie cohort study. Am J Epidemiol 140: 489-499 (1994).
7. Dietrich KN, Berger OG, Succop PA, Hammond PB, Bornschein RL. The developmental consequences of low to moderate prenatal and postnatal lead exposure: intellectual attainment in the Cincinnati lead study cohort following school entry. Neurotoxicol Teratol 15:37-44 (1993).
8. Bellinger DC, Stiles KM, Needleman HL. Low-level lead exposure, intelligence and academic achievement: a long-term follow-up study. Pediatrics 90:855-861 (1992).
9. Bellinger DC. Interpreting the literature and lead and child development: the neglected role of the "experimental system." Neurotoxicol Teratol 17:201-212 (1995).
10. McMichael AJ, Baghurst PA, Wigg NR, Vimpani GV, Robertson EF, Roberts RJ. Port Pirie cohort study: environmental exposure to lead and children's abilities at the age of four years. N Engl J Med 319:468-475 (1988).
11. Bellinger DC, Sloman J, Leviton A, Rabinowitz M, Needleman HL, Waternaux C. Low-level lead exposure and children's cognitive function in the preschool years. Pediatrics 87:219-227 (1991).
12. Baghurst PA, McMichael AJ, Tong S, Wigg NR, Vimpani GV, Robertson EF. Exposure to environmental lead and visual-motor integration at age 7 years. The Port Pirie cohort study. Epidemiology 6:104-109 (1995).
13. Dietrich KM, Berger OG, Succop PA. Lead exposure and the motor developmental status of urban six-year-old children in the Cincinnati Prospective Study. Pediatrics 91:301-307 (1993).
14. Stiles KM, Bellinger DC. Neuropsychological correlates of low-level lead exposure in school-age children: a prospective study. Neurotoxicol Teratol 15:27-35 (1993).
15. Wechsler D. Manual for the Wechsler Intelligence Scale for Children-Revised. San Antonio, TX:Psychological Corporation, 1974.
16. Wielkiewicz RM. Interpreting low scores on the WISC-R's third factor: it's more than distractability. Psychol Assess 2:91-97 (1990).
17. Prifitera A, Dersh J. Base rates of WISC-III diagnostic subtest patterns among normal, learning-disabled, and ADHD samples. In: Journal of Psychoeducational Assessment Monograph Series: Advances in Psychoeducational Assessment: Wechsler Intelligence Scale for Children (Bracken BA, McCallum S, eds). 3rd ed. Brandon, VT:Clinical Psychology Publishing, 1993;43-55.
18. Schwean VL, Saklofske DH, Yakulic RA, Quinn D. WISC-III performance of ADHD children. In: Journal of Psychoeducational Assessment Monograph Series: Advances in Psychoeducational Assessment: Wechsler Intelligence Scale for Children (Bracken BA, McCallum S, eds). 3rd ed. Brandon, VT:Clinical Psychology Publishing, 1993;56-69.
19. Wechsler D. Manual for the WISC-III. San Antonio, TX:Psychological Corporation, 1991.
20. David OJ, Clark J, Voeller K. Lead and hyper-activity. Lancet 2:900-903 (1972).
21. David OJ, Hoffman SP, Sverd J, Clark J. Lead and hyperactivity: lead levels among hyperactive children. J Abnorm Child Psychol 5:405-416 (1977).
22. Yule W, Urbanowicz M, Lansdown R, Millar I. Teachers' ratings of children's behavior in relation to blood lead levels. Br J Dev Psychol 2:295-305 (1984).
23. Murphy MJ, Graziano JH, Popovac D, Kline J, Mehmeti A, Factor-Litvak P, Ahmedi G, Shrout P, Rajovic L, Nenezic D. Past pregnancy outcomes among women near a lead smelter in Kosovo, Yugoslavia. Am J Public Health 80:33-35 (1990).
24. Factor-Litvak P, Graziano JH, Kline J, Popovac D, Mehmeti A, Ahmedi G, Shrout P, Murphy MJ, Gashi E, Haxhiu R. A prospective study of birthweight and length of gestation in a population surrounding a lead smelter in Kosovo, Yugoslavia. Int J Epidemiol 20:722-728 (1991).
25. Fernandez F, Hilligoss D. An improved graphite furnace method for the determination of lead in blood using matrix modification and the Lvov platform. At Spectrosc 3:130-131 (1982).
26. Piomelli S. A micromethod for free eryrhrocyte porphyrins: the FEP test. J Lab Clin Med 81:932-940 (1973).
27. Miles LEM, Sipschitz DA, Bieter CP, Cook JD. Measurement of serum ferritin by a 2-site immunoradiometric assay. Anal Chem 61:209-224 (1974).
28. Roid GH, Prifitera A, Weiss LG. Replication of the WISC-II factor structure in an independent sample. In: Journal of Psychoeducational Assessment Monograph Series: Advances in Psychoeducational Assessment: Wechsler Intelligence Scale for Children (Bracken BA, McCallum S, eds). 3rd ed. Brandon, VT:Clinical Psychology Publishing, 1993;6-21.
29. Wechsler D. WPPSI-R Manual. San Antonio, Texas:Psychological Corporation, 1989.
30. Caldwell BM, Bradley RH. Home Observation for Measurement of the Environment. Little Rock, AR:University of Arkansas at Little Rock, 1984.
31. Bradley RH, Caldwell BM, Rock SL, Barnard KE, Gray C, Hammond MA, Mitchell S, Siegel L, Gottfried A, Johnson DL. Home environment and cognitive development in the first 3 years of life: a collaborative study involving six sites and three ethnic groups in North America. Dev Psychol 25:217-235 (1989).
32. Raven JC, Court JH, Raven J. Manual for Raven's Progressive Matrices and Vocabulary Scales (Section 3)-Standard Progressive Matrices. London:Lewis, 1983.
33. SAS Institute. SAS/STAT Users' Guide, Version 6. Cary, NC:SAS Institute, 1989.
34. Baghurst PA. Getting the lead out.... Neurotoxicol Teratol 17:213-214 (1995).
35. Pribram KH. The hippocampal system and recombinant processing. In: The Hippocampus, Vol 4 (Isaacson RL, Pribram KH, eds). New York:Plenum Publishing, 1986;329-370.
36. Burdette LJ, Goldstein R. Long-term behavioral and electro-physiological changes associated with lead exposure at different stages of brain development in the rat. Dev Brain Res 29:101-110 (1986).
37. Louis-Ferdinand RT, Brown DR, Fiddler SF, Daughtrey WC, Klein AW. Morphometric and enzymatic effects of neonatal lead exposure in the rat brain. Toxicol Appl Pharmacol 43:351-360 (1978).
38. Munoz C, Garbe K, Lilienthal H, Winneke G. Significance of hippocampal dysfunction in low level lead exposure of rats. Neurotoxicol Teratol 10:245-253 (1988).
39. Grandjean P. Regional distribution of lead in human brains. Toxicol Lett 2:65-69 (1978).
40. Silva P, Hughes P, Williams S, Faed J. Blood lead, intelligence, reading attainment, and behaviour in eleven-year-old children in Dunedin, New Zealand. J Child Psychol Psychiatry 29:43-52 (1988).
41. Thomson G, Raab G, Hepburn W, Hunter R, Fulton M, Laxen D. Blood-lead levels and children's behaviour - results from the Edinburgh lead study. J Child Psychol Psychiatry 30:515-528 (1989).
42. Wasserman GA, Staghezza-Jaramillo B, Shrout P, Popovac D, Graziano JH. The effect of lead exposure on preschool behavior problems. Am J Public Health (in press).