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Volumn 161, Issue 5, 2017, Pages 433-439

Interleukin-22 restored mitochondrial damage and impaired glucose-stimulated insulin secretion through down-regulation of uncoupling protein-2 in INS-1 cells

Author keywords

Glucose stimulated insulin secretion; Interleukin 22; Mitochondrial membrane potential; Palmitate; Uncoupling protein 2

Indexed keywords

GENIPIN; GLUCOSE; INTERLEUKIN 22; PALMITIC ACID; UNCOUPLING PROTEIN 2; INSULIN; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22;

EID: 85016446703     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvw084     Document Type: Article
Times cited : (16)

References (41)
  • 1
    • 0035856920 scopus 로고    scopus 로고
    • Global and societal implications of the diabetes epidemic
    • Zimmet, P., Alberti, K.G., and Shaw, J. (2001) Global and societal implications of the diabetes epidemic. Nature 414, 782-787
    • (2001) Nature , vol.414 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.2    Shaw, J.3
  • 3
    • 9444242665 scopus 로고    scopus 로고
    • Five stages of evolving beta-cell dysfunction during progression to diabetes
    • Weir, G.C. and Bonner-Weir, S. (2004). Five stages of evolving beta-cell dysfunction during progression to diabetes. Diabetes 53(Suppl 3), S16-S21
    • (2004) Diabetes , vol.53 , pp. S16-S21
    • Weir, G.C.1    Bonner-Weir, S.2
  • 4
    • 70449099192 scopus 로고    scopus 로고
    • Mitochondria mediated cell death in diabetes
    • Szabadkai, G. and Duchen, M.R. (2009). Mitochondria mediated cell death in diabetes. Apoptosis 14, 1405-1423
    • (2009) Apoptosis , vol.14 , pp. 1405-1423
    • Szabadkai, G.1    Duchen, M.R.2
  • 5
    • 84925581056 scopus 로고    scopus 로고
    • A role for interleukin- 22 in the alleviation of metabolic syndrome
    • Dalmas, E. and Donath, M.Y. (2014) A role for interleukin- 22 in the alleviation of metabolic syndrome. Nat Med 20, 1379-1381
    • (2014) Nat Med , vol.20 , pp. 1379-1381
    • Dalmas, E.1    Donath, M.Y.2
  • 6
    • 84900354047 scopus 로고    scopus 로고
    • Targeting interleukin-22 in psoriasis
    • Hao, J.Q. (2014) Targeting interleukin-22 in psoriasis. Inflammation 37, 94-99
    • (2014) Inflammation , vol.37 , pp. 94-99
    • Hao, J.Q.1
  • 10
    • 84862769727 scopus 로고    scopus 로고
    • Interleukin-22 promotes proliferation of liver stem/progenitor cells in mice and patients with chronic hepatitis B virus infection
    • e187
    • Feng, D., Kong, X., Weng, H., Park, O., Wang, H., Dooley, S., Gershwin, M.E., and Gao, B. (2012) Interleukin-22 promotes proliferation of liver stem/progenitor cells in mice and patients with chronic hepatitis B virus infection. Gastroenterology 143, 188-198, e187
    • (2012) Gastroenterology , vol.143 , pp. 188-198
    • Feng, D.1    Kong, X.2    Weng, H.3    Park, O.4    Wang, H.5    Dooley, S.6    Gershwin, M.E.7    Gao, B.8
  • 15
    • 84855584488 scopus 로고    scopus 로고
    • Mitochondrial uncoupling protein 2 (UCP2) in glucose and lipid metabolism
    • Diano, S. and Horvath, T.L. (2012) Mitochondrial uncoupling protein 2 (UCP2) in glucose and lipid metabolism. Trends Mol Med 18, 52-58
    • (2012) Trends Mol Med , vol.18 , pp. 52-58
    • Diano, S.1    Horvath, T.L.2
  • 16
    • 33749666308 scopus 로고    scopus 로고
    • Uncoupling proteins, dietary fat and the metabolic syndrome
    • Fisler, J.S. and Warden, C.H. (2006) Uncoupling proteins, dietary fat and the metabolic syndrome. Nutr Metab 3, 38
    • (2006) Nutr Metab , vol.3 , pp. 38
    • Fisler, J.S.1    Warden, C.H.2
  • 17
    • 0035875066 scopus 로고    scopus 로고
    • The pancreatic beta cell heats up: UCP2 and insulin secretion in diabetes
    • Polonsky, K.S. and Semenkovich, C.F. (2001) The pancreatic beta cell heats up: UCP2 and insulin secretion in diabetes. Cell 105, 705-707
    • (2001) Cell , vol.105 , pp. 705-707
    • Polonsky, K.S.1    Semenkovich, C.F.2
  • 21
    • 77951274305 scopus 로고    scopus 로고
    • Uncoupling protein UCP2: When mitochondrial activity meets immunity
    • Emre, Y. and Nubel, T. (2010) Uncoupling protein UCP2: when mitochondrial activity meets immunity. FEBS Lett 584, 1437-1442
    • (2010) FEBS Lett , vol.584 , pp. 1437-1442
    • Emre, Y.1    Nubel, T.2
  • 22
    • 0037341238 scopus 로고    scopus 로고
    • Glucose toxicity in beta-cells: Type 2 diabetes, good radicals gone bad, and the glutathione connection
    • Robertson, R.P., Harmon, J., Tran, P.O., Tanaka, Y., and Takahashi, H. (2003) Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection. Diabetes 52, 581-587
    • (2003) Diabetes , vol.52 , pp. 581-587
    • Robertson, R.P.1    Harmon, J.2    Tran, P.O.3    Tanaka, Y.4    Takahashi, H.5
  • 23
    • 0032898667 scopus 로고    scopus 로고
    • Fatty acids, lipotoxicity and insulin secretion
    • McGarry, J.D. and Dobbins, R.L. (1999) Fatty acids, lipotoxicity and insulin secretion. Diabetologia 42, 128-138
    • (1999) Diabetologia , vol.42 , pp. 128-138
    • McGarry, J.D.1    Dobbins, R.L.2
  • 25
    • 0037033039 scopus 로고    scopus 로고
    • Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants
    • Echtay, K.S., Murphy, M.P., Smith, R.A., Talbot, D.A., and Brand, M.D. (2002) Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants. J Biol Chem 277, 47129-47135
    • (2002) J Biol Chem , vol.277 , pp. 47129-47135
    • Echtay, K.S.1    Murphy, M.P.2    Smith, R.A.3    Talbot, D.A.4    Brand, M.D.5
  • 26
    • 84876484085 scopus 로고    scopus 로고
    • Overexpression of the antioxidant enzyme catalase does not interfere with the glucose responsiveness of insulin-secreting INS-1E cells and rat islets
    • Lortz, S., Gurgul-Convey, E., Naujok, O., and Lenzen, S. (2013) Overexpression of the antioxidant enzyme catalase does not interfere with the glucose responsiveness of insulin-secreting INS-1E cells and rat islets. Diabetologia 56, 774-782
    • (2013) Diabetologia , vol.56 , pp. 774-782
    • Lortz, S.1    Gurgul-Convey, E.2    Naujok, O.3    Lenzen, S.4
  • 27
    • 0029151863 scopus 로고
    • Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications
    • Unger, R.H. (1995) Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications. Diabetes 44, 863-870
    • (1995) Diabetes , vol.44 , pp. 863-870
    • Unger, R.H.1
  • 29
    • 0036315888 scopus 로고    scopus 로고
    • Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: Evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and bcl-2 regulated
    • Lupi, R., Dotta, F., Marselli, L., Del Guerra, S., Masini, M., Santangelo, C., Patane, G., Boggi, U., Piro, S., Anello, M., Bergamini, E., Mosca, F., Di Mario, U., Del Prato, S., and Marchetti, P. (2002) Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated. Diabetes 51, 1437-1442
    • (2002) Diabetes , vol.51 , pp. 1437-1442
    • Lupi, R.1    Dotta, F.2    Marselli, L.3    Del Guerra, S.4    Masini, M.5    Santangelo, C.6    Patane, G.7    Boggi, U.8    Piro, S.9    Anello, M.10    Bergamini, E.11    Mosca, F.12    Di Mario, U.13    Del Prato, S.14    Marchetti, P.15
  • 31
    • 0036724133 scopus 로고    scopus 로고
    • Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition
    • Patane, G., Anello, M., Piro, S., Vigneri, R., Purrello, F., and Rabuazzo, A.M. (2002) Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition. Diabetes 51, 2749-2756
    • (2002) Diabetes , vol.51 , pp. 2749-2756
    • Patane, G.1    Anello, M.2    Piro, S.3    Vigneri, R.4    Purrello, F.5    Rabuazzo, A.M.6
  • 32
    • 84855181568 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and beta-cell failure in type 2 diabetes mellitus
    • Ma, Z.A., Zhao, Z., and Turk, J. (2012) Mitochondrial dysfunction and beta-cell failure in type 2 diabetes mellitus. Exp diabetes Res 703538. doi:10.1155/2012/703538
    • (2012) Exp Diabetes Res , pp. 703538
    • Ma, Z.A.1    Zhao, Z.2    Turk, J.3
  • 33
  • 34
    • 0035117975 scopus 로고    scopus 로고
    • Effects of adenoviral overexpression of uncoupling protein-2 and -3 on mitochondrial respiration in insulinoma cells
    • Hong, Y., Fink, B.D., Dillon, J.S. and Sivitz, W.I. (2001). Effects of adenoviral overexpression of uncoupling protein-2 and -3 on mitochondrial respiration in insulinoma cells. Endocrinology 142, 249-256
    • (2001) Endocrinology , vol.142 , pp. 249-256
    • Hong, Y.1    Fink, B.D.2    Dillon, J.S.3    Sivitz, W.I.4
  • 35
    • 0036829870 scopus 로고    scopus 로고
    • Uncoupling protein 2 knockout mice have enhanced insulin secretory capacity after a high-fat diet
    • Joseph, J.W., Koshkin, V., Zhang, C.Y., Wang, J., Lowell, B.B., Chan, C.B., and Wheeler, M.B. (2002) Uncoupling protein 2 knockout mice have enhanced insulin secretory capacity after a high-fat diet. Diabetes 51, 3211-3219
    • (2002) Diabetes , vol.51 , pp. 3211-3219
    • Joseph, J.W.1    Koshkin, V.2    Zhang, C.Y.3    Wang, J.4    Lowell, B.B.5    Chan, C.B.6    Wheeler, M.B.7
  • 36
    • 33744548069 scopus 로고    scopus 로고
    • Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity-and high glucose-induced beta cell dysfunction in isolated pancreatic islets
    • Zhang, C.Y., Parton, L.E., Ye, C.P., Krauss, S., Shen, R., Lin, C.T., Porco, J.A., Jr., and Lowell, B.B. (2006) Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity-and high glucose-induced beta cell dysfunction in isolated pancreatic islets. Cell Metab 3, 417-427
    • (2006) Cell Metab , vol.3 , pp. 417-427
    • Zhang, C.Y.1    Parton, L.E.2    Ye, C.P.3    Krauss, S.4    Shen, R.5    Lin, C.T.6    Porco, J.A.7    Lowell, B.B.8
  • 37
    • 84873688049 scopus 로고    scopus 로고
    • IL-22, not simply a Th17 cytokine
    • Rutz, S., Eidenschenk, C., and Ouyang, W. (2013) IL-22, not simply a Th17 cytokine. Immunol Rev 252, 116-132
    • (2013) Immunol Rev , vol.252 , pp. 116-132
    • Rutz, S.1    Eidenschenk, C.2    Ouyang, W.3
  • 39
    • 84958225902 scopus 로고    scopus 로고
    • Interleukin-22 alleviated palmitate-induced endoplasmic reticulum stress in INS-1 cells through activation of autophagy
    • Hu, M., Yang, S., Yang, L., Cheng, Y., and Zhang, H. (2016) Interleukin-22 alleviated palmitate-induced endoplasmic reticulum stress in INS-1 cells through activation of autophagy. PLoS One 11, e0146818
    • (2016) PLoS One , vol.11 , pp. e0146818
    • Hu, M.1    Yang, S.2    Yang, L.3    Cheng, Y.4    Zhang, H.5
  • 40
    • 25144476923 scopus 로고    scopus 로고
    • Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3
    • Brand, M.D. and Esteves, T.C. (2005) Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3. Cell Metab 2, 85-93
    • (2005) Cell Metab , vol.2 , pp. 85-93
    • Brand, M.D.1    Esteves, T.C.2
  • 41
    • 33646188854 scopus 로고    scopus 로고
    • Enhanced colon tumor induction in uncoupling protein-2 deficient mice is associated with NF-kappaB activation and oxidative stress
    • Derdak, Z., Fulop, P., Sabo, E., Tavares, R., Berthiaume, E.P., Resnick, M.B., Paragh, G., Wands, J.R., and Baffy, G. (2006) Enhanced colon tumor induction in uncoupling protein-2 deficient mice is associated with NF-kappaB activation and oxidative stress. Carcinogenesis 27, 956-961
    • (2006) Carcinogenesis , vol.27 , pp. 956-961
    • Derdak, Z.1    Fulop, P.2    Sabo, E.3    Tavares, R.4    Berthiaume, E.P.5    Resnick, M.B.6    Paragh, G.7    Wands, J.R.8    Baffy, G.9


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