Neuroprotective Functions for the Histone Deacetylase SIRT6

Cell Reports

Volumn 18, Issue 13, 2017, Pages 3052-3062

  Kaluski, Shai ^a   Portillo, Miguel ^a   Besnard, Antoine ^b,c   Stein, Daniel ^a   Einav, Monica ^a   Zhong, Lei ^b,c   Ueberham, Uwe ^d   Arendt, Thomas ^d   Mostoslavsky, Raul ^b,c   Sahay, Amar ^b,c   Toiber, Debra ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

aging; Alzheimer's disease; DNA damage; GSK3; SIRT6; Tau

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; HISTONE DEACETYLASE; HISTONE DEACETYLASE SIRT6; MESSENGER RNA; TAU PROTEIN; UNCLASSIFIED DRUG; ATM PROTEIN; GLYCOGEN SYNTHASE KINASE 3; SIRT6 PROTEIN, HUMAN; SIRT6 PROTEIN, MOUSE; SIRTUIN;

ANIMAL CELL; ARTICLE; BEHAVIOR DISORDER; CELL DEATH; CONTROLLED STUDY; DEGENERATIVE DISEASE; DNA DAMAGE; ENZYME ACTIVATION; FEMALE; GENOMIC INSTABILITY; LEARNING DISORDER; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; SURVIVAL RATE; ALZHEIMER DISEASE; ANIMAL; ANTAGONISTS AND INHIBITORS; ANTIBODY SPECIFICITY; APOPTOSIS; BRAIN; C57BL MOUSE; DEFICIENCY; GENE DELETION; HUMAN; KNOCKOUT MOUSE; LEARNING; METABOLISM; PATHOLOGY; PHENOTYPE; PHOSPHORYLATION;

ALZHEIMER DISEASE; ANIMALS; APOPTOSIS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; BRAIN; DNA DAMAGE; ENZYME ACTIVATION; GENE DELETION; GENOMIC INSTABILITY; GLYCOGEN SYNTHASE KINASE 3; HUMANS; LEARNING; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUROPROTECTION; ORGAN SPECIFICITY; PHENOTYPE; PHOSPHORYLATION; PROTEIN STABILITY; SIRTUINS; TAU PROTEINS;

EID: 85016236945     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.03.008     Document Type: Article

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