Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss

Neuron

Volumn 90, Issue 2, 2016, Pages 245-260

  Tracy, Tara E ^a,b   Sohn, Peter Dongmin ^a,c   Minami, S Sakura ^a,b   Wang, Chao ^a,b   Min, Sang Won ^a,b   Li, Yaqiao ^a   Zhou, Yungui ^a   Le, David ^a   Lo, Iris ^a   Ponnusamy, Ravikumar ^a   Cong, Xin ^d   Schilling, Birgit ^d   Ellerby, Lisa M ^d   Huganir, Richard L ^e   Gan, Li ^a,b,c  

^a GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; AMPA RECEPTOR; GLUTAMINE; KIBRA PROTEIN; LYSINE; POSTSYNAPTIC RECEPTOR; TAU PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; KIBRA PROTEIN, MOUSE;

ACTIN POLYMERIZATION; ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMNESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; GENE MUTATION; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; LONG TERM POTENTIATION; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; PROTEIN ACETYLATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TAUOPATHY; TRANSGENIC MOUSE; ACETYLATION; ANIMAL; BRAIN; GENETICS; MEMORY DISORDER; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PRIMARY CELL CULTURE;

ACETYLATION; ACTINS; ALZHEIMER DISEASE; ANIMALS; BRAIN; CARRIER PROTEINS; HIPPOCAMPUS; HUMANS; LONG-TERM POTENTIATION; MEMORY DISORDERS; MICE; MICE, TRANSGENIC; NEURONAL PLASTICITY; PRIMARY CELL CULTURE; RECEPTORS, AMPA; SIGNAL TRANSDUCTION; TAU PROTEINS;

EID: 84962090722     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2016.03.005     Document Type: Article

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