Structure and functional properties of norrin mimic wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan

eLife

Volumn 4, Issue JULY 2015, 2015, Pages 1-27

  Chang, Tao Hsin ^a   Hsieh, Fu Lien ^a,b   Zebisch, Matthias ^a,c   Harlos, Karl ^a   Elegheert, Jonathan ^a   Jones, E Yvonne ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Evotec Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FRIZZLED 4 PROTEIN; GLYCOSAMINOGLYCAN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; NORRIE DISEASE PROTEIN; PROTEIN; PROTEOGLYCAN; TETRASPANIN; UNCLASSIFIED DRUG; WNT PROTEIN; EYE PROTEIN; FRIZZLED PROTEIN; FZD4 PROTEIN, HUMAN; LRP5 PROTEIN, MOUSE; LRP6 PROTEIN, MOUSE; MUTANT PROTEIN; NDP PROTEIN, HUMAN; NERVE PROTEIN;

AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE; RADIATION SCATTERING; SEQUENCE ALIGNMENT; SURFACE PLASMON RESONANCE; WESTERN BLOTTING; WNT SIGNALING PATHWAY; XENOPUS; CHEMISTRY; GENETICS; METABOLISM; PROTEIN CONFORMATION; SMALL ANGLE SCATTERING; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; EYE PROTEINS; FRIZZLED RECEPTORS; HUMANS; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-5; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-6; MUTANT PROTEINS; NERVE TISSUE PROTEINS; PROTEIN CONFORMATION; PROTEOGLYCANS; SCATTERING, SMALL ANGLE;

EID: 85016043869     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.06554     Document Type: Article

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