Structural and functional studies of LRP6 ectodomain reveal a platform for Wnt signaling

Developmental Cell

Volumn 21, Issue 5, 2011, Pages 848-861

  Chen, Shuo ^a   Bubeck, Doryen ^a   MacDonald, Bryan T ^b   Liang, Wen Xue ^c   Mao, Jian Hua ^c   Malinauskas, Tomas ^a   Llorca, Oscar ^d   Aricescu, A Radu ^a   Siebold, Christian ^a   He, Xi ^b   Jones, E Yvonne ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b HARVARD MEDICAL SCHOOL   (United States)

^c SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^d CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DICKKOPF 1 PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; WNT PROTEIN; WNT1 PROTEIN; WNT3A PROTEIN;

ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ELECTRON MICROSCOPY; EMBRYO; GENE MAPPING; HUMAN; HUMAN CELL; KIDNEY CELL; MUTATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HUMANS; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-6; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 80755186530     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2011.09.007     Document Type: Article

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