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Volumn 18, Issue 3, 2017, Pages

Understanding the effectiveness of natural compound mixtures in cancer through their molecular mode of action

Author keywords

Apoptosis; Cancer; Chemosensitization; Metal derivatized natural compounds; MicroRNA; Natural compound mixtures

Indexed keywords

ABC TRANSPORTER; ALKALOID; ANTINEOPLASTIC AGENT; CHIKUSETSU SAPONIN; CURCUMIN; CYCLOOXYGENASE 2; DIOSGENIN; DITERPENOID; FLAVONOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; NATURAL PRODUCT; OXYMATRINE; SAPONIN; TETRANDRINE; TRANSCRIPTOME; HERBACEOUS AGENT;

EID: 85015973785     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms18030656     Document Type: Review
Times cited : (259)

References (135)
  • 1
    • 0042844744 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the period 1981-2002
    • CrossRef, PubMed
    • Newman, D.J.; Cragg, G.M.; Snader, K.M. Natural products as sources of new drugs over the period 1981-2002. J. Nat. Prod. 2003, 66, 1022-1037. [CrossRef] [PubMed]
    • (2003) J. Nat. Prod. , vol.66 , pp. 1022-1037
    • Newman, D.J.1    Cragg, G.M.2    Snader, K.M.3
  • 3
    • 0037204952 scopus 로고    scopus 로고
    • The Fas signaling pathway: More than a paradigm
    • CrossRef, PubMed
    • Wajant, H. The Fas signaling pathway: More than a paradigm. Science 2002, 296, 1635-1636. [CrossRef] [PubMed]
    • (2002) Science , vol.296 , pp. 1635-1636
    • Wajant, H.1
  • 5
    • 79251468749 scopus 로고    scopus 로고
    • Dependence receptors: From basic research to drug development
    • CrossRef, PubMed
    • Mehlen, P.; Bredesen, D.E. Dependence receptors: From basic research to drug development. Sci. Signal. 2011, 4, mr2. [CrossRef] [PubMed]
    • (2011) Sci. Signal. , vol.4 , pp. mr2
    • Mehlen, P.1    Bredesen, D.E.2
  • 6
    • 80053348989 scopus 로고    scopus 로고
    • Apoptosis in cancer: From pathogenesis to treatment
    • CrossRef, PubMed
    • Wong, R. Apoptosis in cancer: From pathogenesis to treatment. J. Exp. Clin. Cancer Res. 2011, 30, 87. [CrossRef] [PubMed]
    • (2011) J. Exp. Clin. Cancer Res. , vol.30 , pp. 87
    • Wong, R.1
  • 7
    • 85015942408 scopus 로고    scopus 로고
    • Downregulation of ASPP2 improves hepatocellular carcinoma cells survival via promoting BECN1-dependent autophagy initiation
    • CrossRef, PubMed
    • Chen, R.; Wang, H.; Liang, B.; Liu, G.; Tang, M.; Jia, R.; Fan, X.; Jing, W.; Zhou, X.; Wang, H. Downregulation of ASPP2 improves hepatocellular carcinoma cells survival via promoting BECN1-dependent autophagy initiation. Cell Death Dis. 2016, 7, e2512. [CrossRef] [PubMed]
    • (2016) Cell Death Dis. , vol.7 , pp. e2512
    • Chen, R.1    Wang, H.2    Liang, B.3    Liu, G.4    Tang, M.5    Jia, R.6    Fan, X.7    Jing, W.8    Zhou, X.9    Wang, H.10
  • 8
    • 33749184334 scopus 로고    scopus 로고
    • Atg5: More than an autophagy factor
    • CrossRef, PubMed
    • Codogno, P.; Meijer, A.J. Atg5: More than an autophagy factor. Nat. Cell Biol. 2006, 8, 1045-1046. [CrossRef] [PubMed]
    • (2006) Nat. Cell Biol. , vol.8 , pp. 1045-1046
    • Codogno, P.1    Meijer, A.J.2
  • 9
    • 0033569423 scopus 로고    scopus 로고
    • INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53
    • CrossRef, PubMed
    • Schmitt, C.A.; McCurrach, M.E.; de Stanchina, E.; Wallace-Brodeur, R.R.; Lowe, S.W. INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53. Genes Dev. 1999, 13, 2670-2677. [CrossRef] [PubMed]
    • (1999) Genes Dev. , vol.13 , pp. 2670-2677
    • Schmitt, C.A.1    McCurrach, M.E.2    De Stanchina, E.3    Wallace-Brodeur, R.R.4    Lowe, S.W.5
  • 10
    • 0025880971 scopus 로고
    • Drug-target interactions: Only the first step in the commitment to a programmed cell death?
    • PubMed
    • Dive, C.; Hickman, J. Drug-target interactions: Only the first step in the commitment to a programmed cell death? Br. J. Cancer 1991, 64, 192. [PubMed]
    • (1991) Br. J. Cancer , vol.64 , pp. 192
    • Dive, C.1    Hickman, J.2
  • 11
    • 77954813506 scopus 로고    scopus 로고
    • Circumvention of multi-drug resistance of cancer cells by Chinese herbal medicines
    • CrossRef, PubMed
    • Chai, S.; To, K.; Lin, G. Circumvention of multi-drug resistance of cancer cells by Chinese herbal medicines. Chin. Med. 2010, 5, 26. [CrossRef] [PubMed]
    • (2010) Chin. Med. , vol.5 , pp. 26
    • Chai, S.1    To, K.2    Lin, G.3
  • 12
    • 0036902141 scopus 로고    scopus 로고
    • Potential role of tetrandrine in cancer therapy
    • Yu-Jen, C. Potential role of tetrandrine in cancer therapy. Acta Pharmacol. Sin. 2002, 23, 1102-1106.
    • (2002) Acta Pharmacol. Sin. , vol.23 , pp. 1102-1106
    • Yu-Jen, C.1
  • 13
    • 0031107257 scopus 로고    scopus 로고
    • A comparative study on effect of two bisbenzylisoquinolines, tetrandrine and berbamine, on reversal of multidrug resistance
    • Tian, H.; Pan, Q. A comparative study on effect of two bisbenzylisoquinolines, tetrandrine and berbamine, on reversal of multidrug resistance. Acta Pharm. Sin. 1997, 32, 245-250.
    • (1997) Acta Pharm. Sin. , vol.32 , pp. 245-250
    • Tian, H.1    Pan, Q.2
  • 14
    • 7144259744 scopus 로고    scopus 로고
    • The bis benzylisoquinoline alkaloids, tetrandine and fangchinoline, enhance the cytotoxicity of multidrug resistance-related drugs via modulation of P-glycoprotein
    • CrossRef, PubMed
    • Choi, S.-U.; Park, S.-H.; Kim, K.-H.; Choi, E.-J.; Kim, S.; Park, W.-K.; Zhang, Y.-H.; Kim, H.-S.; Jung, N.-P.; Lee, C.-O. The bis benzylisoquinoline alkaloids, tetrandine and fangchinoline, enhance the cytotoxicity of multidrug resistance-related drugs via modulation of P-glycoprotein. Anti Cancer Drugs 1998, 9, 255-262. [CrossRef] [PubMed]
    • (1998) Anti Cancer Drugs , vol.9 , pp. 255-262
    • Choi, S.-U.1    Park, S.-H.2    Kim, K.-H.3    Choi, E.-J.4    Kim, S.5    Park, W.-K.6    Zhang, Y.-H.7    Kim, H.-S.8    Jung, N.-P.9    Lee, C.-O.10
  • 15
    • 84884567357 scopus 로고    scopus 로고
    • Rhamnetin and cirsiliol induce radiosensitization and inhibition of epithelial-mesenchymal transition (EMT) by miR-34a-mediated suppression of Notch-1 expression in non-small cell lung cancer cell lines
    • CrossRef, PubMed
    • Kang, J.; Kim, E.; Kim, W.; Seong, K.M.; Youn, H.; Kim, J.W.; Kim, J.; Youn, B. Rhamnetin and cirsiliol induce radiosensitization and inhibition of epithelial-mesenchymal transition (EMT) by miR-34a-mediated suppression of Notch-1 expression in non-small cell lung cancer cell lines. J. Biol. Chem. 2013, 288, 27343-27357. [CrossRef] [PubMed]
    • (2013) J. Biol. Chem. , vol.288 , pp. 27343-27357
    • Kang, J.1    Kim, E.2    Kim, W.3    Seong, K.M.4    Youn, H.5    Kim, J.W.6    Kim, J.7    Youn, B.8
  • 16
    • 84937826667 scopus 로고    scopus 로고
    • Robust gene expression and mutation analyses of RNA-sequencing of formalin-fixed diagnostic tumor samples
    • CrossRef, PubMed
    • Graw, S.; Meier, R.; Minn, K.; Bloomer, C.; Godwin, A.K.; Fridley, B.; Vlad, A.; Beyerlein, P.; Chien, J. Robust gene expression and mutation analyses of RNA-sequencing of formalin-fixed diagnostic tumor samples. Sci. Rep. 2015, 5, 12335. [CrossRef] [PubMed]
    • (2015) Sci. Rep. , vol.5 , pp. 12335
    • Graw, S.1    Meier, R.2    Minn, K.3    Bloomer, C.4    Godwin, A.K.5    Fridley, B.6    Vlad, A.7    Beyerlein, P.8    Chien, J.9
  • 17
    • 0034630167 scopus 로고    scopus 로고
    • Induction of apoptosis by cancer chemotherapy
    • CrossRef, PubMed
    • Kaufmann, S.H.; Earnshaw,W.C. Induction of apoptosis by cancer chemotherapy. Exp. Cell Res. 2000, 256, 42-49. [CrossRef] [PubMed]
    • (2000) Exp. Cell Res. , vol.256 , pp. 42-49
    • Kaufmann, S.H.1    Earnshaw, W.C.2
  • 18
    • 0242475357 scopus 로고    scopus 로고
    • Classification of anticancer drugs-A new system based on therapeutic targets
    • CrossRef
    • Espinosa, E.; Zamora, P.; Feliu, J.; Barón, M.G. Classification of anticancer drugs-A new system based on therapeutic targets. Cancer Treat. Rev. 2003, 29, 515-523. [CrossRef]
    • (2003) Cancer Treat. Rev. , vol.29 , pp. 515-523
    • Espinosa, E.1    Zamora, P.2    Feliu, J.3    Barón, M.G.4
  • 19
    • 0037248328 scopus 로고    scopus 로고
    • Cancer prevention-the potential for diet to modulate molecular signalling
    • CrossRef
    • Manson, M.M. Cancer prevention-the potential for diet to modulate molecular signalling. Trends Mol. Med. 2003, 9, 11-18. [CrossRef]
    • (2003) Trends Mol. Med. , vol.9 , pp. 11-18
    • Manson, M.M.1
  • 20
    • 84901374871 scopus 로고    scopus 로고
    • Anticancer potential of plants and natural products: A review
    • CrossRef
    • Prakash, O.; Kumar, A.; Kumar, P. Anticancer potential of plants and natural products: A review. Am. J. Pharmacol. Sci. 2013, 1, 104-115. [CrossRef]
    • (2013) Am. J. Pharmacol. Sci. , vol.1 , pp. 104-115
    • Prakash, O.1    Kumar, A.2    Kumar, P.3
  • 21
    • 84910134369 scopus 로고    scopus 로고
    • Targeting apoptosis pathways in cancer and perspectives with natural compounds from Mother Nature
    • CrossRef, PubMed
    • Millimouno, F.M.; Dong, J.; Yang, L.; Li, J.; Li, X. Targeting apoptosis pathways in cancer and perspectives with natural compounds from Mother Nature. Cancer Prev. Res. 2014, 7, 1081-1107. [CrossRef] [PubMed]
    • (2014) Cancer Prev. Res. , vol.7 , pp. 1081-1107
    • Millimouno, F.M.1    Dong, J.2    Yang, L.3    Li, J.4    Li, X.5
  • 22
    • 77955933845 scopus 로고    scopus 로고
    • Evasion of apoptosis as a cellular stress response in cancer
    • CrossRef, PubMed
    • Fulda, S. Evasion of apoptosis as a cellular stress response in cancer. Int. J. Cell Biol. 2010. [CrossRef] [PubMed]
    • (2010) Int. J. Cell Biol.
    • Fulda, S.1
  • 23
    • 0033509354 scopus 로고    scopus 로고
    • Genistein inhibits NF-κB activation in prostate cancer cells
    • CrossRef, PubMed
    • Davis, J.N.; Kucuk, O.; Sarkar, F.H. Genistein inhibits NF-κB activation in prostate cancer cells. Nutr. Cancer 1999, 35, 167-174. [CrossRef] [PubMed]
    • (1999) Nutr. Cancer , vol.35 , pp. 167-174
    • Davis, J.N.1    Kucuk, O.2    Sarkar, F.H.3
  • 24
    • 0033159534 scopus 로고    scopus 로고
    • The rising incidence of breast cancer in women and prostate cancer in men. Dietary influences: A possible preventive role for nature’s sex hormone modifiers-the phytoestrogens (review)
    • CrossRef, PubMed
    • Stephens, F.O. The rising incidence of breast cancer in women and prostate cancer in men. Dietary influences: A possible preventive role for nature’s sex hormone modifiers-the phytoestrogens (review). Oncol. Rep. 1999, 6, 865-935. [CrossRef] [PubMed]
    • (1999) Oncol. Rep. , vol.6 , pp. 865-935
    • Stephens, F.O.1
  • 25
    • 84876560772 scopus 로고    scopus 로고
    • NPACT: Naturally occurring plant-based anti-cancer compound-activity-target database
    • CrossRef, PubMed
    • Mangal, M.; Sagar, P.; Singh, H.; Raghava, G.P.; Agarwal, S.M. NPACT: Naturally occurring plant-based anti-cancer compound-activity-target database. Nucleic Acids Res. 2013, 41, D1124-D1129. [CrossRef] [PubMed]
    • (2013) Nucleic Acids Res. , vol.41 , pp. D1124-D1129
    • Mangal, M.1    Sagar, P.2    Singh, H.3    Raghava, G.P.4    Agarwal, S.M.5
  • 26
    • 84981333189 scopus 로고    scopus 로고
    • Synergistic effects of Chinese herbal medicine: A comprehensive review of methodology and current research
    • CrossRef, PubMed
    • Zhou, X.; Seto, S.W.; Chang, D.; Kiat, H.; Razmovski-Naumovski, V.; Chan, K.; Bensoussan, A. Synergistic effects of Chinese herbal medicine: A comprehensive review of methodology and current research. Front. Pharmacol. 2016, 7, 201. [CrossRef] [PubMed]
    • (2016) Front. Pharmacol. , vol.7 , pp. 201
    • Zhou, X.1    Seto, S.W.2    Chang, D.3    Kiat, H.4    Razmovski-Naumovski, V.5    Chan, K.6    Bensoussan, A.7
  • 27
    • 84940961606 scopus 로고    scopus 로고
    • Traditional Chinese medicine and cancer: History, present situation, and development
    • CrossRef, PubMed
    • Liu, J.;Wang, S.; Zhang, Y.; Fan, H.T.; Lin, H.S. Traditional Chinese medicine and cancer: History, present situation, and development. Thorac. Cancer 2015, 6, 561-569. [CrossRef] [PubMed]
    • (2015) Thorac. Cancer , vol.6 , pp. 561-569
    • Liu, J.1    Wang, S.2    Zhang, Y.3    Fan, H.T.4    Lin, H.S.5
  • 28
    • 0036803909 scopus 로고    scopus 로고
    • Bioactive polysaccharides from traditional Chinese medicine herbs as anticancer adjuvants
    • CrossRef, PubMed
    • Chang, R. Bioactive polysaccharides from traditional Chinese medicine herbs as anticancer adjuvants. J. Altern. Complement. Med. 2002, 8, 559-565. [CrossRef] [PubMed]
    • (2002) J. Altern. Complement. Med. , vol.8 , pp. 559-565
    • Chang, R.1
  • 29
    • 85015817784 scopus 로고    scopus 로고
    • Chinese herbal medicine for advanced pancreatic cancer
    • CrossRef
    • Ni, Y.H.; Li, X.; Xu, Y.; Liu, J.P. Chinese herbal medicine for advanced pancreatic cancer. Cochrane Libr. 2012. [CrossRef]
    • (2012) Cochrane Libr.
    • Ni, Y.H.1    Li, X.2    Xu, Y.3    Liu, J.P.4
  • 30
    • 34548624310 scopus 로고    scopus 로고
    • Chinese medicinal herbs to treat the side-effects of chemotherapy in breast cancer patients
    • CrossRef
    • Zhang, M.; Liu, X.; Li, J.; He, L.; Tripathy, D. Chinese medicinal herbs to treat the side-effects of chemotherapy in breast cancer patients. Cochrane Libr. 2007. [CrossRef]
    • (2007) Cochrane Libr.
    • Zhang, M.1    Liu, X.2    Li, J.3    He, L.4    Tripathy, D.5
  • 32
    • 25444513400 scopus 로고    scopus 로고
    • In vitro anticancer activity of twelve Chinese medicinal herbs
    • CrossRef, PubMed
    • Shoemaker, M.; Hamilton, B.; Dairkee, S.H.; Cohen, I.; Campbell, M.J. In vitro anticancer activity of twelve Chinese medicinal herbs. Phytother. Res. 2005, 19, 649-651. [CrossRef] [PubMed]
    • (2005) Phytother. Res. , vol.19 , pp. 649-651
    • Shoemaker, M.1    Hamilton, B.2    Dairkee, S.H.3    Cohen, I.4    Campbell, M.J.5
  • 33
    • 0038689359 scopus 로고    scopus 로고
    • Inhibition of human cancer cell line growth and human umbilical vein endothelial cell angiogenesis by artemisinin derivatives in vitro
    • CrossRef
    • Chen, H.-H.; Zhou, H.-J.; Fang, X. Inhibition of human cancer cell line growth and human umbilical vein endothelial cell angiogenesis by artemisinin derivatives in vitro. Pharmacol. Res. 2003, 48, 231-236. [CrossRef]
    • (2003) Pharmacol. Res. , vol.48 , pp. 231-236
    • Chen, H.-H.1    Zhou, H.-J.2    Fang, X.3
  • 35
    • 0035992781 scopus 로고    scopus 로고
    • Traditional Chinese medicine (TCM): Are polyphenols and saponins the key ingredients triggering biological activities?
    • CrossRef, PubMed
    • Liu, J.; Henkel, T. Traditional Chinese medicine (TCM): Are polyphenols and saponins the key ingredients triggering biological activities? Curr. Med. Chem. 2002, 9, 1483-1485. [CrossRef] [PubMed]
    • (2002) Curr. Med. Chem. , vol.9 , pp. 1483-1485
    • Liu, J.1    Henkel, T.2
  • 36
    • 0017191015 scopus 로고
    • Types of anticancer agents isolated from plants
    • PubMed
    • Hartwell, J. Types of anticancer agents isolated from plants. Cancer Treat. Rep. 1976, 60, 1031-1067. [PubMed]
    • (1976) Cancer Treat. Rep. , vol.60 , pp. 1031-1067
    • Hartwell, J.1
  • 38
    • 31044440371 scopus 로고    scopus 로고
    • Antimicrobial activity of berberine alone and in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus
    • CrossRef, PubMed
    • Yu, H.-H.; Kim, K.-J.; Cha, J.-D.; Kim, H.-K.; Lee, Y.-E.; Choi, N.-Y.; You, Y.-O. Antimicrobial activity of berberine alone and in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus. J. Med. Food 2005, 8, 454-461. [CrossRef] [PubMed]
    • (2005) J. Med. Food , vol.8 , pp. 454-461
    • Yu, H.-H.1    Kim, K.-J.2    Cha, J.-D.3    Kim, H.-K.4    Lee, Y.-E.5    Choi, N.-Y.6    You, Y.-O.7
  • 39
    • 79959964544 scopus 로고    scopus 로고
    • Modulating gut microbiota as an anti-diabetic mechanism of berberine
    • CrossRef
    • Han, J.; Lin, H.; Huang, W. Modulating gut microbiota as an anti-diabetic mechanism of berberine. Med. Sci. Monit. Basic Res. 2011, 17, RA164-RA167. [CrossRef]
    • (2011) Med. Sci. Monit. Basic Res. , vol.17 , pp. RA164-RA167
    • Han, J.1    Lin, H.2    Huang, W.3
  • 42
    • 84904719739 scopus 로고    scopus 로고
    • Anti-tumor activities of matrine and oxymatrine: Literature review
    • CrossRef, PubMed
    • Liu, Y.; Xu, Y.; Ji, W.; Li, X.; Sun, B.; Gao, Q.; Su, C. Anti-tumor activities of matrine and oxymatrine: Literature review. Tumor Biol. 2014, 35, 5111-5119. [CrossRef] [PubMed]
    • (2014) Tumor Biol. , vol.35 , pp. 5111-5119
    • Liu, Y.1    Xu, Y.2    Ji, W.3    Li, X.4    Sun, B.5    Gao, Q.6    Su, C.7
  • 43
    • 84856765126 scopus 로고    scopus 로고
    • Matrine induces caspase-dependent apoptosis in human osteosarcoma cells in vitro and in vivo through the upregulation of Bax and Fas/FasL and downregulation of Bcl-2
    • CrossRef, PubMed
    • Liang, C.Z.; Zhang, J.K.; Shi, Z.; Liu, B.; Shen, C.Q.; Tao, H.M. Matrine induces caspase-dependent apoptosis in human osteosarcoma cells in vitro and in vivo through the upregulation of Bax and Fas/FasL and downregulation of Bcl-2. Cancer Chemother. Pharmacol. 2012, 69, 317-331. [CrossRef] [PubMed]
    • (2012) Cancer Chemother. Pharmacol. , vol.69 , pp. 317-331
    • Liang, C.Z.1    Zhang, J.K.2    Shi, Z.3    Liu, B.4    Shen, C.Q.5    Tao, H.M.6
  • 44
    • 70449534614 scopus 로고    scopus 로고
    • Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-κB signaling
    • CrossRef, PubMed
    • Yu, P.; Liu, Q.; Liu, K.; Yagasaki, K.;Wu, E.; Zhang, G. Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-κB signaling. Cytotechnology 2009, 59, 219-229. [CrossRef] [PubMed]
    • (2009) Cytotechnology , vol.59 , pp. 219-229
    • Yu, P.1    Liu, Q.2    Liu, K.3    Yagasaki, K.4    Wu, E.5    Zhang, G.6
  • 45
    • 84900407710 scopus 로고    scopus 로고
    • Effects of matrine on the proliferation and apoptosis of human medulloblastoma cell line D341
    • PubMed
    • Zhou, K.; Ji, H.; Mao, T.; Bai, Z. Effects of matrine on the proliferation and apoptosis of human medulloblastoma cell line D341. Int. J. Clin. Exp. Med. 2014, 7, 911-918. [PubMed]
    • (2014) Int. J. Clin. Exp. Med. , vol.7 , pp. 911-918
    • Zhou, K.1    Ji, H.2    Mao, T.3    Bai, Z.4
  • 46
    • 84932640736 scopus 로고    scopus 로고
    • Matrine-induced autophagy regulated by p53 through AMP-activated protein kinase in human hepatoma cells
    • CrossRef, PubMed
    • Xie, S.-B.; He, X.-X.; Yao, S.-K. Matrine-induced autophagy regulated by p53 through AMP-activated protein kinase in human hepatoma cells. Int. J. Oncol. 2015, 47, 517-526. [CrossRef] [PubMed]
    • (2015) Int. J. Oncol. , vol.47 , pp. 517-526
    • Xie, S.-B.1    He, X.-X.2    Yao, S.-K.3
  • 48
    • 84925324049 scopus 로고    scopus 로고
    • Fatty acid trafficking in starved cells: Regulation by lipid droplet lipolysis, autophagy, and mitochondrial fusion dynamics
    • CrossRef, PubMed
    • Rambold, A.S.; Cohen, S.; Lippincott-Schwartz, J. Fatty acid trafficking in starved cells: Regulation by lipid droplet lipolysis, autophagy, and mitochondrial fusion dynamics. Dev. Cell 2015, 32, 678-692. [CrossRef] [PubMed]
    • (2015) Dev. Cell , vol.32 , pp. 678-692
    • Rambold, A.S.1    Cohen, S.2    Lippincott-Schwartz, J.3
  • 49
    • 33744994567 scopus 로고    scopus 로고
    • Glutathione in cancer biology and therapy
    • CrossRef, PubMed
    • Estrela, J.M.; Ortega, A.; Obrador, E. Glutathione in cancer biology and therapy. Crit. Rev. Clin. Lab. Sci. 2006, 43, 143-181. [CrossRef] [PubMed]
    • (2006) Crit. Rev. Clin. Lab. Sci. , vol.43 , pp. 143-181
    • Estrela, J.M.1    Ortega, A.2    Obrador, E.3
  • 50
    • 16344395310 scopus 로고    scopus 로고
    • Experimental study of the killing effects of oxymatrine on human colon cancer cell line SW1116
    • CrossRef, PubMed
    • Zou, J.; Ran, Z.H.; Xu, Q.; Xiao, S.D. Experimental study of the killing effects of oxymatrine on human colon cancer cell line SW1116. Chin. J. Dig. Dis. 2005, 6, 15-20. [CrossRef] [PubMed]
    • (2005) Chin. J. Dig. Dis. , vol.6 , pp. 15-20
    • Zou, J.1    Ran, Z.H.2    Xu, Q.3    Xiao, S.D.4
  • 52
    • 80051925957 scopus 로고    scopus 로고
    • Preparation and in vitro anticancer activity of oxymatrine mixed micellar nanoparticles
    • Jin, N.; Zhao, Y.-X.; Deng, S.-H.; Sun, Q. Preparation and in vitro anticancer activity of oxymatrine mixed micellar nanoparticles. Die Pharm. Int. J. Pharm. Sci. 2011, 66, 506-510.
    • (2011) Die Pharm. Int. J. Pharm. Sci. , vol.66 , pp. 506-510
    • Jin, N.1    Zhao, Y.-X.2    Deng, S.-H.3    Sun, Q.4
  • 53
    • 84978878273 scopus 로고    scopus 로고
    • Oxymatrine inhibited cell proliferation by inducing apoptosis in human lung cancer A549 cells
    • CrossRef, PubMed
    • Wang, B.; Han, Q.; Zhu, Y. Oxymatrine inhibited cell proliferation by inducing apoptosis in human lung cancer A549 cells. Bio Med. Mater. Eng. 2015, 26, 165-172. [CrossRef] [PubMed]
    • (2015) Bio Med. Mater. Eng. , vol.26 , pp. 165-172
    • Wang, B.1    Han, Q.2    Zhu, Y.3
  • 54
    • 84891878070 scopus 로고    scopus 로고
    • Oxymatrine induces apoptosis in human cervical cancer cells through guanine nucleotide depletion
    • CrossRef, PubMed
    • Li, M.; Su, B.-S.; Chang, L.-H.; Gao, Q.; Chen, K.-L.; An, P.; Huang, C.; Yang, J.; Li, Z.-F. Oxymatrine induces apoptosis in human cervical cancer cells through guanine nucleotide depletion. Anti Cancer Drugs 2014, 25, 161-173. [CrossRef] [PubMed]
    • (2014) Anti Cancer Drugs , vol.25 , pp. 161-173
    • Li, M.1    Su, B.-S.2    Chang, L.-H.3    Gao, Q.4    Chen, K.-L.5    An, P.6    Huang, C.7    Yang, J.8    Li, Z.-F.9
  • 55
    • 72949109102 scopus 로고    scopus 로고
    • Tetrandrine induces apoptosis and growth suppression of colon cancer cells in mice
    • CrossRef, PubMed
    • Wu, J.-M.; Chen, Y.; Chen, J.-C.; Lin, T.-Y.; Tseng, S.-H. Tetrandrine induces apoptosis and growth suppression of colon cancer cells in mice. Cancer Lett. 2010, 287, 187-195. [CrossRef] [PubMed]
    • (2010) Cancer Lett. , vol.287 , pp. 187-195
    • Wu, J.-M.1    Chen, Y.2    Chen, J.-C.3    Lin, T.-Y.4    Tseng, S.-H.5
  • 56
    • 84885027804 scopus 로고    scopus 로고
    • Tetrandrine induces mitochondria-mediated apoptosis in human gastric cancer BGC-823 cells
    • CrossRef, PubMed
    • Qin, R.; Shen, H.; Cao, Y.; Fang, Y.; Li, H.; Chen, Q.; Xu, W. Tetrandrine induces mitochondria-mediated apoptosis in human gastric cancer BGC-823 cells. PLoS ONE 2013, 8, e76486. [CrossRef] [PubMed]
    • (2013) PLoS ONE , vol.8 , pp. e76486
    • Qin, R.1    Shen, H.2    Cao, Y.3    Fang, Y.4    Li, H.5    Chen, Q.6    Xu, W.7
  • 57
    • 0029923972 scopus 로고    scopus 로고
    • Differential effects of vinblastine on polymerization and dynamics at opposite microtubule ends
    • CrossRef, PubMed
    • Panda, D.; Jordan, M.A.; Chu, K.C.; Wilson, L. Differential effects of vinblastine on polymerization and dynamics at opposite microtubule ends. J. Biol. Chem. 1996, 271, 29807-29812. [CrossRef] [PubMed]
    • (1996) J. Biol. Chem. , vol.271 , pp. 29807-29812
    • Panda, D.1    Jordan, M.A.2    Chu, K.C.3    Wilson, L.4
  • 58
    • 77649160262 scopus 로고    scopus 로고
    • Single-drug vinblastine as salvage treatment for refractory or relapsed anaplastic large-cell lymphoma: A report from the French Society of Pediatric Oncology
    • CrossRef, PubMed
    • Brugières, L.; Pacquement, H.; Le Deley, M.-C.; Leverger, G.; Lutz, P.; Paillard, C.; Baruchel, A.; Frappaz, D.; Nelken, B.; Lamant, L. Single-drug vinblastine as salvage treatment for refractory or relapsed anaplastic large-cell lymphoma: A report from the French Society of Pediatric Oncology. J. Clin. Oncol. 2009, 27, 5056-5061. [CrossRef] [PubMed]
    • (2009) J. Clin. Oncol. , vol.27 , pp. 5056-5061
    • Brugières, L.1    Pacquement, H.2    Le Deley, M.-C.3    Leverger, G.4    Lutz, P.5    Paillard, C.6    Baruchel, A.7    Frappaz, D.8    Nelken, B.9    Lamant, L.10
  • 61
    • 67149144583 scopus 로고    scopus 로고
    • Anti-inflammatory and antiproliferative activities of trifolirhizin, a flavonoid from Sophora flavescens roots
    • CrossRef, PubMed
    • Zhou, H.; Lutterodt, H.; Cheng, Z.; Yu, L. Anti-inflammatory and antiproliferative activities of trifolirhizin, a flavonoid from Sophora flavescens roots. J. Agric. Food Chem. 2009, 57, 4580-4585. [CrossRef] [PubMed]
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 4580-4585
    • Zhou, H.1    Lutterodt, H.2    Cheng, Z.3    Yu, L.4
  • 62
    • 84936775256 scopus 로고    scopus 로고
    • Developing an activity and absorption-based quality control platform for Chinese traditional medicine: Application to Zeng-Sheng-Ping (Antitumor B)
    • CrossRef, PubMed
    • Yin, T.; Yang, G.; Ma, Y.; Xu, B.; Hu, M.; You, M.; Gao, S. Developing an activity and absorption-based quality control platform for Chinese traditional medicine: Application to Zeng-Sheng-Ping (Antitumor B). J. Ethnopharmacol. 2015, 172, 195-201. [CrossRef] [PubMed]
    • (2015) J. Ethnopharmacol. , vol.172 , pp. 195-201
    • Yin, T.1    Yang, G.2    Ma, Y.3    Xu, B.4    Hu, M.5    You, M.6    Gao, S.7
  • 63
    • 16644388839 scopus 로고    scopus 로고
    • Induction of apoptosis by maackiain and trifolirhizin (maackiain glycoside) isolated from sanzukon (Sophora Subprostrate Chen et T. Chen) in human promyelotic leukemia HL-60 cells
    • CrossRef, PubMed
    • Aratanechemuge, Y.; Hibasami, H.; Katsuzaki, H.; Imai, K.; Komiya, T. Induction of apoptosis by maackiain and trifolirhizin (maackiain glycoside) isolated from sanzukon (Sophora Subprostrate Chen et T. Chen) in human promyelotic leukemia HL-60 cells. Oncol. Rep. 2004, 12, 1183-1188. [CrossRef] [PubMed]
    • (2004) Oncol. Rep. , vol.12 , pp. 1183-1188
    • Aratanechemuge, Y.1    Hibasami, H.2    Katsuzaki, H.3    Imai, K.4    Komiya, T.5
  • 64
    • 79958139961 scopus 로고    scopus 로고
    • Proteomic identification of differentially expressed proteins in curcumin-treated MCF-7 cells
    • CrossRef, PubMed
    • Fang, H.; Chen, S.; Guo, D.; Pan, S.; Yu, Z. Proteomic identification of differentially expressed proteins in curcumin-treated MCF-7 cells. Phytomedicine 2011, 18, 697-703. [CrossRef] [PubMed]
    • (2011) Phytomedicine , vol.18 , pp. 697-703
    • Fang, H.1    Chen, S.2    Guo, D.3    Pan, S.4    Yu, Z.5
  • 65
    • 73349094986 scopus 로고    scopus 로고
    • Curcumin and cancer cells: How many ways can curry kill tumor cells selectively?
    • CrossRef, PubMed
    • Ravindran, J.; Prasad, S.; Aggarwal, B.B. Curcumin and cancer cells: How many ways can curry kill tumor cells selectively? AAPS J. 2009, 11, 495-510. [CrossRef] [PubMed]
    • (2009) AAPS J. , vol.11 , pp. 495-510
    • Ravindran, J.1    Prasad, S.2    Aggarwal, B.B.3
  • 66
    • 84962850834 scopus 로고    scopus 로고
    • Molecular mechanisms of curcumin and its semisynthetic analogues in prostate cancer prevention and treatment
    • CrossRef, PubMed
    • Jordan, B.C.; Mock, C.D.; Thilagavathi, R.; Selvam, C. Molecular mechanisms of curcumin and its semisynthetic analogues in prostate cancer prevention and treatment. Life Sci. 2016, 152, 135-144. [CrossRef] [PubMed]
    • (2016) Life Sci. , vol.152 , pp. 135-144
    • Jordan, B.C.1    Mock, C.D.2    Thilagavathi, R.3    Selvam, C.4
  • 67
    • 85015038999 scopus 로고    scopus 로고
    • The Essential Medicinal Chemistry of Curcumin: Miniperspective
    • CrossRef, PubMed
    • Nelson, K.M.; Dahlin, J.L.; Bisson, J.; Graham, J.; Pauli, G.F.;Walters, M.A. The Essential Medicinal Chemistry of Curcumin: Miniperspective. J. Med. Chem. 2017, 60, 1620-1637. [CrossRef] [PubMed]
    • (2017) J. Med. Chem. , vol.60 , pp. 1620-1637
    • Nelson, K.M.1    Dahlin, J.L.2    Bisson, J.3    Graham, J.4    Pauli, G.F.5    Walters, M.A.6
  • 68
    • 85016141071 scopus 로고    scopus 로고
    • Deceptive curcumin offers cautionary tale for chemists
    • CrossRef, PubMed
    • Baker, M.M. Deceptive curcumin offers cautionary tale for chemists. Nature 2017, 541, 144-145. [CrossRef] [PubMed]
    • (2017) Nature , vol.541 , pp. 144-145
    • Baker, M.M.1
  • 69
    • 84895170428 scopus 로고    scopus 로고
    • Site-specific anticancer effects of dietary flavonoid quercetin
    • CrossRef, PubMed
    • Sak, K. Site-specific anticancer effects of dietary flavonoid quercetin. Nutr. Cancer 2014, 66, 177-193. [CrossRef] [PubMed]
    • (2014) Nutr. Cancer , vol.66 , pp. 177-193
    • Sak, K.1
  • 70
    • 58649083936 scopus 로고    scopus 로고
    • Effects of low dose quercetin: Cancer cell-specific inhibition of cell cycle progression
    • CrossRef, PubMed
    • Jeong, J.H.; An, J.Y.; Kwon, Y.T.; Rhee, J.G.; Lee, Y.J. Effects of low dose quercetin: Cancer cell-specific inhibition of cell cycle progression. J. Cell. Biochem. 2009, 106, 73-82. [CrossRef] [PubMed]
    • (2009) J. Cell. Biochem. , vol.106 , pp. 73-82
    • Jeong, J.H.1    An, J.Y.2    Kwon, Y.T.3    Rhee, J.G.4    Lee, Y.J.5
  • 71
    • 84884789465 scopus 로고    scopus 로고
    • Effects of quercetin on the proliferation of breast cancer cells and expression of survivin in vitro
    • PubMed
    • Deng, X.-H.; Song, H.-Y.; Zhou, Y.-F.; Yuan, G.-Y.; Zheng, F.-J. Effects of quercetin on the proliferation of breast cancer cells and expression of survivin in vitro. Exp. Ther. Med. 2013, 6, 1155-1158. [PubMed]
    • (2013) Exp. Ther. Med. , vol.6 , pp. 1155-1158
    • Deng, X.-H.1    Song, H.-Y.2    Zhou, Y.-F.3    Yuan, G.-Y.4    Zheng, F.-J.5
  • 72
    • 64549111348 scopus 로고    scopus 로고
    • Quantitative proteomic analysis of HepG2 cells treated with quercetin suggests IQGAP1 involved in quercetin-induced regulation of cell proliferation and migration
    • CrossRef, PubMed
    • Zhou, J.; Liang, S.; Fang, L.; Chen, L.; Tang, M.; Xu, Y.; Fu, A.; Yang, J.; Wei, Y. Quantitative proteomic analysis of HepG2 cells treated with quercetin suggests IQGAP1 involved in quercetin-induced regulation of cell proliferation and migration. OMICS J. Integr. Biol. 2009, 13, 93-103. [CrossRef] [PubMed]
    • (2009) OMICS J. Integr. Biol. , vol.13 , pp. 93-103
    • Zhou, J.1    Liang, S.2    Fang, L.3    Chen, L.4    Tang, M.5    Xu, Y.6    Fu, A.7    Yang, J.8    Wei, Y.9
  • 73
    • 77956655047 scopus 로고    scopus 로고
    • Chemical study and medical application of saponins as anti-cancer agents
    • CrossRef, PubMed
    • Man, S.; Gao, W.; Zhang, Y.; Huang, L.; Liu, C. Chemical study and medical application of saponins as anti-cancer agents. Fitoterapia 2010, 81, 703-714. [CrossRef] [PubMed]
    • (2010) Fitoterapia , vol.81 , pp. 703-714
    • Man, S.1    Gao, W.2    Zhang, Y.3    Huang, L.4    Liu, C.5
  • 74
    • 0034111413 scopus 로고    scopus 로고
    • Chinese medicinal herb, Acanthopanax gracilistylus, extract induces cell cycle arrest of human tumor cells in vitro
    • CrossRef, PubMed
    • Shan, B.E.; Zeki, K.; Sugiura, T.; Yoshida, Y.; Yamashita, U. Chinese medicinal herb, Acanthopanax gracilistylus, extract induces cell cycle arrest of human tumor cells in vitro. Jpn. J. Cancer Res. 2000, 91, 383-389. [CrossRef] [PubMed]
    • (2000) Jpn. J. Cancer Res. , vol.91 , pp. 383-389
    • Shan, B.E.1    Zeki, K.2    Sugiura, T.3    Yoshida, Y.4    Yamashita, U.5
  • 75
    • 84971643869 scopus 로고    scopus 로고
    • Chikusetsusaponin IVa butyl ester (CS-IVa-Be), a novel IL-6R antagonist, inhibits IL-6/STAT3 signaling pathway and induces cancer cell apoptosis
    • CrossRef, PubMed
    • Yang, J.; Qian, S.; Cai, X.; Lu,W.; Hu, C.; Sun, X.; Yang, Y.; Yu, Q.; Gao, S.P.; Cao, P. Chikusetsusaponin IVa butyl ester (CS-IVa-Be), a novel IL-6R antagonist, inhibits IL-6/STAT3 signaling pathway and induces cancer cell apoptosis. Mol. Cancer Ther. 2016, 15, 1190-1200. [CrossRef] [PubMed]
    • (2016) Mol. Cancer Ther. , vol.15 , pp. 1190-1200
    • Yang, J.1    Qian, S.2    Cai, X.3    Lu, W.4    Hu, C.5    Sun, X.6    Yang, Y.7    Yu, Q.8    Gao, S.P.9    Cao, P.10
  • 76
    • 33646422206 scopus 로고    scopus 로고
    • Effects of polyphyllin D, a steroidal saponin in Paris polyphylla, in growth inhibition of human breast cancer cells and in xenograft
    • CrossRef, PubMed
    • Lee, M.-S.; Chan, J.Y.-W.; Kong, S.-K.; Yu, B.; Eng-Choon, V.O.; Nai-Ching, H.W.; Mak Chung-Wai, T.; Fung, K.-P. Effects of polyphyllin D, a steroidal saponin in Paris polyphylla, in growth inhibition of human breast cancer cells and in xenograft. Cancer Biol. Ther. 2005, 4, 1248-1254. [CrossRef] [PubMed]
    • (2005) Cancer Biol. Ther. , vol.4 , pp. 1248-1254
    • Lee, M.-S.1    Chan, J.Y.-W.2    Kong, S.-K.3    Yu, B.4    Eng-Choon, V.O.5    Nai-Ching, H.W.6    Mak Chung-Wai, T.7    Fung, K.-P.8
  • 77
    • 34547945104 scopus 로고    scopus 로고
    • Diosgenin, a naturally occurring furostanol saponin suppresses 3-hydroxy-3-methylglutaryl CoA reductase expression and induces apoptosis in HCT-116 human colon carcinoma cells
    • CrossRef, PubMed
    • Raju, J.; Bird, R.P. Diosgenin, a naturally occurring furostanol saponin suppresses 3-hydroxy-3-methylglutaryl CoA reductase expression and induces apoptosis in HCT-116 human colon carcinoma cells. Cancer Lett. 2007, 255, 194-204. [CrossRef] [PubMed]
    • (2007) Cancer Lett. , vol.255 , pp. 194-204
    • Raju, J.1    Bird, R.P.2
  • 78
    • 36849074161 scopus 로고    scopus 로고
    • Diosgenin, a naturally occurring steroid, suppresses fatty acid synthase expression in HER2-overexpressing breast cancer cells through modulating Akt, mTOR and JNK phosphorylation
    • CrossRef, PubMed
    • Chiang, C.-T.; Way, T.-D.; Tsai, S.-J.; Lin, J.-K. Diosgenin, a naturally occurring steroid, suppresses fatty acid synthase expression in HER2-overexpressing breast cancer cells through modulating Akt, mTOR and JNK phosphorylation. FEBS Lett. 2007, 581, 5735-5742. [CrossRef] [PubMed]
    • (2007) FEBS Lett. , vol.581 , pp. 5735-5742
    • Chiang, C.-T.1    Way, T.-D.2    Tsai, S.-J.3    Lin, J.-K.4
  • 79
    • 67349257797 scopus 로고    scopus 로고
    • Macranthoside B, a hederagenin saponin extracted from Lonicera macranthoides and its anti-tumor activities in vitro and in vivo
    • CrossRef, PubMed
    • Wang, J.; Zhao, X.-Z.; Qi, Q.; Tao, L.; Zhao, Q.; Mu, R.; Gu, H.-Y.; Wang, M.; Feng, X.; Guo, Q.-L. Macranthoside B, a hederagenin saponin extracted from Lonicera macranthoides and its anti-tumor activities in vitro and in vivo. Food Chem. Toxicol. 2009, 47, 1716-1721. [CrossRef] [PubMed]
    • (2009) Food Chem. Toxicol. , vol.47 , pp. 1716-1721
    • Wang, J.1    Zhao, X.-Z.2    Qi, Q.3    Tao, L.4    Zhao, Q.5    Mu, R.6    Gu, H.-Y.7    Wang, M.8    Feng, X.9    Guo, Q.-L.10
  • 80
    • 84962778867 scopus 로고    scopus 로고
    • Macranthoside B Induces Apoptosis and Autophagy Via Reactive Oxygen Species Accumulation in Human Ovarian Cancer A2780 Cells
    • CrossRef, PubMed
    • Shan, Y.; Guan, F.; Zhao, X.; Wang, M.; Chen, Y.; Wang, Q.; Feng, X. Macranthoside B Induces Apoptosis and Autophagy Via Reactive Oxygen Species Accumulation in Human Ovarian Cancer A2780 Cells. Nutr. Cancer 2016, 68, 280-289. [CrossRef] [PubMed]
    • (2016) Nutr. Cancer , vol.68 , pp. 280-289
    • Shan, Y.1    Guan, F.2    Zhao, X.3    Wang, M.4    Chen, Y.5    Wang, Q.6    Feng, X.7
  • 82
    • 84887563876 scopus 로고    scopus 로고
    • Identification and determination of the chemical constituents in a herbal preparation, Compound Kushen injection, by HPLC and LC-DAD-MS/MS
    • CrossRef
    • Ma, Y.; Gao, H.; Liu, J.; Chen, L.; Zhang, Q.; Wang, Z. Identification and determination of the chemical constituents in a herbal preparation, Compound Kushen injection, by HPLC and LC-DAD-MS/MS. J. Liq. Chromatogr. Relat. Technol. 2014, 37, 207-220. [CrossRef]
    • (2014) J. Liq. Chromatogr. Relat. Technol. , vol.37 , pp. 207-220
    • Ma, Y.1    Gao, H.2    Liu, J.3    Chen, L.4    Zhang, Q.5    Wang, Z.6
  • 84
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • CrossRef, PubMed
    • Polakis, P. Wnt signaling and cancer. Genes Dev. 2000, 14, 1837-1851. [CrossRef] [PubMed]
    • (2000) Genes Dev. , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 85
    • 80054998123 scopus 로고    scopus 로고
    • Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/b-catenin pathway
    • CrossRef, PubMed
    • Xu,W.; Lin, H.; Zhang, Y.; Chen, X.; Hua, B.; Hou,W.; Qi, X.; Pei, Y.; Zhu, X.; Zhao, Z. Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/b-catenin pathway. J. Exp. Clin. Cancer Res. 2011, 30, 103. [CrossRef] [PubMed]
    • (2011) J. Exp. Clin. Cancer Res. , vol.30 , pp. 103
    • Xu, W.1    Lin, H.2    Zhang, Y.3    Chen, X.4    Hua, B.5    Hou, W.6    Qi, X.7    Pei, Y.8    Zhu, X.9    Zhao, Z.10
  • 87
    • 84994180818 scopus 로고    scopus 로고
    • Identification of Candidate Anti-Cancer Molecular Mechanisms Of Compound Kushen Injection Using Functional Genomics
    • CrossRef, PubMed
    • Qu, Z.; Cui, J.; Harata-Lee, Y.; Aung, T.N.; Feng, Q.; Raison, J.; Kortschak, R.D.; Adelson, D.L. Identification of Candidate Anti-Cancer Molecular Mechanisms Of Compound Kushen Injection Using Functional Genomics. Oncotarget 2016, 7, 66003-66019. [CrossRef] [PubMed]
    • (2016) Oncotarget , vol.7 , pp. 66003-66019
    • Qu, Z.1    Cui, J.2    Harata-Lee, Y.3    Aung, T.N.4    Feng, Q.5    Raison, J.6    Kortschak, R.D.7    Adelson, D.L.8
  • 88
    • 84964961668 scopus 로고    scopus 로고
    • Long noncoding RNA H19 regulates EZH2 expression by interacting with miR-630 and promotes cell invasion in nasopharyngeal carcinoma
    • Xudong, L.; Yan, L.; Xi, Y.; Xiaoguang, W.; Xiaoguang, H. Long noncoding RNA H19 regulates EZH2 expression by interacting with miR-630 and promotes cell invasion in nasopharyngeal carcinoma. Biochem. Biophys. Res. Commun. 2016, 473, 913-919.
    • (2016) Biochem. Biophys. Res. Commun. , vol.473 , pp. 913-919
    • Xudong, L.1    Yan, L.2    Xi, Y.3    Xiaoguang, W.4    Xiaoguang, H.5
  • 89
    • 2342622022 scopus 로고    scopus 로고
    • Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models
    • CrossRef, PubMed
    • Zhang, Z.; Wang, Y.; Yao, R.; Li, J.; Yan, Y.; La Regina, M.; Lemon,W.L.; Grubbs, C.J.; Lubet, R.A.; You, M. Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models. Oncogene 2004, 23, 3841-3850. [CrossRef] [PubMed]
    • (2004) Oncogene , vol.23 , pp. 3841-3850
    • Zhang, Z.1    Wang, Y.2    Yao, R.3    Li, J.4    Yan, Y.5    La Regina, M.6    Lemon, W.L.7    Grubbs, C.J.8    Lubet, R.A.9    You, M.10
  • 90
    • 84862943135 scopus 로고    scopus 로고
    • Inhibitory effects of Zengshengping fractions on DMBA-induced buccal pouch carcinogenesis in hamsters
    • CrossRef, PubMed
    • Guan, X.; Sun, Z.; Chen, X.; Wu, H.; Zhang, X. Inhibitory effects of Zengshengping fractions on DMBA-induced buccal pouch carcinogenesis in hamsters. Chin. Med. J. 2012, 125, 332-337. [CrossRef] [PubMed]
    • (2012) Chin. Med. J. , vol.125 , pp. 332-337
    • Guan, X.1    Sun, Z.2    Chen, X.3    Wu, H.4    Zhang, X.5
  • 91
    • 84865692578 scopus 로고    scopus 로고
    • Effects of Zeng Sheng Ping/ACAPHA on Malignant Brain Tumor Growth and Notch Signaling
    • PubMed
    • Lim, K.J.; Rajan, K.; Eberhart, C.G. Effects of Zeng Sheng Ping/ACAPHA on Malignant Brain Tumor Growth and Notch Signaling. Anticancer Res. 2012, 32, 2689-2696. [PubMed]
    • (2012) Anticancer Res. , vol.32 , pp. 2689-2696
    • Lim, K.J.1    Rajan, K.2    Eberhart, C.G.3
  • 92
    • 74649086130 scopus 로고    scopus 로고
    • Chemoprevention of oral cancer in animal models, and effect on leukoplakias in human patients with ZengShengPing, a mixture of medicinal herbs
    • CrossRef, PubMed
    • Sun, Z.; Guan, X.; Li, N.; Liu, X.; Chen, X. Chemoprevention of oral cancer in animal models, and effect on leukoplakias in human patients with ZengShengPing, a mixture of medicinal herbs. Oral Oncol. 2010, 46, 105-110. [CrossRef] [PubMed]
    • (2010) Oral Oncol. , vol.46 , pp. 105-110
    • Sun, Z.1    Guan, X.2    Li, N.3    Liu, X.4    Chen, X.5
  • 93
    • 0028100892 scopus 로고
    • Mutant alpha subunits of G12 and G13 proteins induce neoplastic transformation of Rat-1 fibroblasts
    • PubMed
    • Voyno-Yasenetskaya, T.A.; Pace, A.M.; Bourne, H.R. Mutant alpha subunits of G12 and G13 proteins induce neoplastic transformation of Rat-1 fibroblasts. Oncogene 1994, 9, 2559-2565. [PubMed]
    • (1994) Oncogene , vol.9 , pp. 2559-2565
    • Voyno-Yasenetskaya, T.A.1    Pace, A.M.2    Bourne, H.R.3
  • 94
    • 0032561309 scopus 로고    scopus 로고
    • Regulation of apoptosis by α-subunits of G12 and G13 proteins via apoptosis signal-regulating kinase-1
    • CrossRef, PubMed
    • Berestetskaya, Y.V.; Faure, M.P.; Ichijo, H.; Voyno-Yasenetskaya, T.A. Regulation of apoptosis by α-subunits of G12 and G13 proteins via apoptosis signal-regulating kinase-1. J. Biol. Chem. 1998, 273, 27816-27823. [CrossRef] [PubMed]
    • (1998) J. Biol. Chem. , vol.273 , pp. 27816-27823
    • Berestetskaya, Y.V.1    Faure, M.P.2    Ichijo, H.3    Voyno-Yasenetskaya, T.A.4
  • 95
    • 77953757262 scopus 로고    scopus 로고
    • Differentially expressed proteins of MCF-7 human breast cancer cells affected by Zilongjin, a complementary Chinese herbal medicine
    • CrossRef, PubMed
    • Tian, Z.H.; Li, Z.F.; Zhou, S.B.; Liang, Y.Y.; He, D.C.; Wang, D.S. Differentially expressed proteins of MCF-7 human breast cancer cells affected by Zilongjin, a complementary Chinese herbal medicine. Proteom. Clin. Appl. 2010, 4, 550-559. [CrossRef] [PubMed]
    • (2010) Proteom. Clin. Appl. , vol.4 , pp. 550-559
    • Tian, Z.H.1    Li, Z.F.2    Zhou, S.B.3    Liang, Y.Y.4    He, D.C.5    Wang, D.S.6
  • 96
    • 80053371077 scopus 로고    scopus 로고
    • Genome wide expression analysis of the effect of the Chinese patent medicine zilongjin tablet on four human lung carcinoma cell lines
    • CrossRef, PubMed
    • Zhang, P.;Wang, X.; Xiong, S.;Wen, S.; Gao, S.;Wang, L.; Cao, B. Genome wide expression analysis of the effect of the Chinese patent medicine zilongjin tablet on four human lung carcinoma cell lines. Phytother. Res. 2011, 25, 1472-1479. [CrossRef] [PubMed]
    • (2011) Phytother. Res. , vol.25 , pp. 1472-1479
    • Zhang, P.1    Wang, X.2    Xiong, S.3    Wen, S.4    Gao, S.5    Wang, L.6    Cao, B.7
  • 97
    • 0029897210 scopus 로고    scopus 로고
    • Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest
    • CrossRef, PubMed
    • Huang, L.-C.; Clarkin, K.C.;Wahl, G.M. Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest. Proc. Natl. Acad. Sci. USA 1996, 93, 4827-4832. [CrossRef] [PubMed]
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4827-4832
    • Huang, L.-C.1    Clarkin, K.C.2    Wahl, G.M.3
  • 98
    • 45249120387 scopus 로고    scopus 로고
    • Metabonomics study on the effects of the ginsenoside Rg3 in a β-cyclodextrin-based formulation on tumor-bearing rats by a fully automatic hydrophilic interaction/reversed-phase column-switching HPLC-ESI-MS approach
    • CrossRef, PubMed
    • Wang, Y.; Wang, J.; Yao, M.; Zhao, X.; Fritsche, J.; Schmitt-Kopplin, P.; Cai, Z.; Wan, D.; Lu, X.; Yang, S. Metabonomics study on the effects of the ginsenoside Rg3 in a β-cyclodextrin-based formulation on tumor-bearing rats by a fully automatic hydrophilic interaction/reversed-phase column-switching HPLC-ESI-MS approach. Anal. Chem. 2008, 80, 4680-4688. [CrossRef] [PubMed]
    • (2008) Anal. Chem. , vol.80 , pp. 4680-4688
    • Wang, Y.1    Wang, J.2    Yao, M.3    Zhao, X.4    Fritsche, J.5    Schmitt-Kopplin, P.6    Cai, Z.7    Wan, D.8    Lu, X.9    Yang, S.10
  • 99
    • 84874584067 scopus 로고    scopus 로고
    • Metabolomics reveals metabolic targets and biphasic responses in breast cancer cells treated by curcumin alone and in association with docetaxel
    • CrossRef, PubMed
    • Bayet-Robert, M.; Morvan, D. Metabolomics reveals metabolic targets and biphasic responses in breast cancer cells treated by curcumin alone and in association with docetaxel. PLoS ONE 2013, 8, e57971. [CrossRef] [PubMed]
    • (2013) PLoS ONE , vol.8 , pp. e57971
    • Bayet-Robert, M.1    Morvan, D.2
  • 100
    • 84941710838 scopus 로고    scopus 로고
    • Toxic Markers of Matrine Determined Using 1H-NMR-Based Metabolomics in Cultured Cells In Vitro and Rats In Vivo
    • CrossRef
    • Li, Z.; Zheng, L.; Shi, J.; Zhang, G.; Lu, L.; Zhu, L.; Zhang, J.; Liu, Z. Toxic Markers of Matrine Determined Using 1H-NMR-Based Metabolomics in Cultured Cells In Vitro and Rats In Vivo. Evid. Based Complement. Altern. Med. 2015. [CrossRef]
    • (2015) Evid. Based Complement. Altern. Med.
    • Li, Z.1    Zheng, L.2    Shi, J.3    Zhang, G.4    Lu, L.5    Zhu, L.6    Zhang, J.7    Liu, Z.8
  • 102
    • 84870292700 scopus 로고    scopus 로고
    • Proteomic analysis of the effect of triterpenes from Patrinia heterophylla on leukemia K562 cells
    • CrossRef, PubMed
    • Wei, D.-F.; Wei, Y.-X.; Cheng, W.-D.; Yan, M.-F.; Su, G.; Hu, Y.; Ma, Y.-Q.; Han, C.; Lu, Y.; Hui-Ming, C. Proteomic analysis of the effect of triterpenes from Patrinia heterophylla on leukemia K562 cells. J. Ethnopharmacol. 2012, 144, 576-583. [CrossRef] [PubMed]
    • (2012) J. Ethnopharmacol. , vol.144 , pp. 576-583
    • Wei, D.-F.1    Wei, Y.-X.2    Cheng, W.-D.3    Yan, M.-F.4    Su, G.5    Hu, Y.6    Ma, Y.-Q.7    Han, C.8    Lu, Y.9    Hui-Ming, C.10
  • 103
    • 84929589862 scopus 로고    scopus 로고
    • Molecular signatures of sanguinarine in human pancreatic cancer cells: A large scale label-free comparative proteomics approach
    • CrossRef, PubMed
    • Singh, C.K.; Kaur, S.; George, J.; Nihal, M.; Hahn, M.C.P.; Scarlett, C.O.; Ahmad, N. Molecular signatures of sanguinarine in human pancreatic cancer cells: A large scale label-free comparative proteomics approach. Oncotarget 2015, 6, 10335. [CrossRef] [PubMed]
    • (2015) Oncotarget , vol.6 , pp. 10335
    • Singh, C.K.1    Kaur, S.2    George, J.3    Nihal, M.4    Hahn, M.C.P.5    Scarlett, C.O.6    Ahmad, N.7
  • 104
    • 79956062622 scopus 로고    scopus 로고
    • Aidi Injection () Alters the Expression Profiles of MicroRNAs in Human Breast Cancer Cells
    • CrossRef
    • Zhang, H.; Zhou, Q.-M.; Lu, Y.-Y.; Jia, D.; Su, S.-B. Aidi Injection () Alters the Expression Profiles of MicroRNAs in Human Breast Cancer Cells. J. Tradit. Chin. Med. 2011, 31, 10-16. [CrossRef]
    • (2011) J. Tradit. Chin. Med. , vol.31 , pp. 10-16
    • Zhang, H.1    Zhou, Q.-M.2    Lu, Y.-Y.3    Jia, D.4    Su, S.-B.5
  • 105
    • 33744486894 scopus 로고    scopus 로고
    • Metal-based antitumour drugs in the post genomic era
    • CrossRef, PubMed
    • Dyson, P.J.; Sava, G. Metal-based antitumour drugs in the post genomic era. Dalton Trans. 2006, 1929-1933. [CrossRef] [PubMed]
    • (2006) Dalton Trans. , pp. 1929-1933
    • Dyson, P.J.1    Sava, G.2
  • 107
    • 44949219131 scopus 로고    scopus 로고
    • A review on plant-derived natural products and their analogs with anti-tumor activity
    • CrossRef
    • Dholwani, K.; Saluja, A.; Gupta, A.; Shah, D. A review on plant-derived natural products and their analogs with anti-tumor activity. Indian J. Pharmacol. 2008, 40, 49-58. [CrossRef]
    • (2008) Indian J. Pharmacol. , vol.40 , pp. 49-58
    • Dholwani, K.1    Saluja, A.2    Gupta, A.3    Shah, D.4
  • 108
    • 78649625578 scopus 로고    scopus 로고
    • Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) matrine with Ga (III), Au (III), Sn (IV) ions, and DNA binding studies
    • CrossRef
    • Chen, Z.-F.; Mao, L.; Liu, L.-M.; Liu, Y.-C.; Peng, Y.; Hong, X.;Wang, H.-H.; Liu, H.-G.; Liang, H. Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) matrine with Ga (III), Au (III), Sn (IV) ions, and DNA binding studies. J. Inorg. Biochem. 2011, 105, 171-180. [CrossRef]
    • (2011) J. Inorg. Biochem. , vol.105 , pp. 171-180
    • Chen, Z.-F.1    Mao, L.2    Liu, L.-M.3    Liu, Y.-C.4    Peng, Y.5    Hong, X.6    Wang, H.-H.7    Liu, H.-G.8    Liang, H.9
  • 109
    • 80052089927 scopus 로고    scopus 로고
    • Synthesis, structures, cellular uptake and apoptosis-inducing properties of highly cytotoxic ruthenium-Norharman complexes
    • CrossRef, PubMed
    • Tan, C.;Wu, S.; Lai, S.;Wang, M.; Chen, Y.; Zhou, L.; Zhu, Y.; Lian,W.; Peng,W.; Ji, L. Synthesis, structures, cellular uptake and apoptosis-inducing properties of highly cytotoxic ruthenium-Norharman complexes. Dalton Trans. 2011, 40, 8611-8621. [CrossRef] [PubMed]
    • (2011) Dalton Trans. , vol.40 , pp. 8611-8621
    • Tan, C.1    Wu, S.2    Lai, S.3    Wang, M.4    Chen, Y.5    Zhou, L.6    Zhu, Y.7    Lian, W.8    Peng, W.9    Ji, L.10
  • 111
    • 70449346930 scopus 로고    scopus 로고
    • Synthesis, cytotoxic activity, and DNA binding properties of copper (II) complexes with hesperetin, naringenin, and apigenin
    • CrossRef, PubMed
    • Tan, M.; Zhu, J.; Pan, Y.; Chen, Z.; Liang, H.; Liu, H.;Wang, H. Synthesis, cytotoxic activity, and DNA binding properties of copper (II) complexes with hesperetin, naringenin, and apigenin. Bioinorg. Chem. Appl. 2009. [CrossRef] [PubMed]
    • (2009) Bioinorg. Chem. Appl.
    • Tan, M.1    Zhu, J.2    Pan, Y.3    Chen, Z.4    Liang, H.5    Liu, H.6    Wang, H.7
  • 112
    • 67649560778 scopus 로고    scopus 로고
    • DNA binding and oxidative DNA damage induced by a quercetin copper (II) complex: Potential mechanism of its antitumor properties
    • CrossRef, PubMed
    • Tan, J.; Wang, B.; Zhu, L. DNA binding and oxidative DNA damage induced by a quercetin copper (II) complex: Potential mechanism of its antitumor properties. JBIC J. Biol. Inorg. Chem. 2009, 14, 727-739. [CrossRef] [PubMed]
    • (2009) JBIC J. Biol. Inorg. Chem. , vol.14 , pp. 727-739
    • Tan, J.1    Wang, B.2    Zhu, L.3
  • 113
    • 2542491777 scopus 로고    scopus 로고
    • The role of ABC transporters in drug resistance, metabolism and toxicity
    • CrossRef, PubMed
    • Glavinas, H.; Krajcsi, P.; Cserepes, J.; Sarkadi, B. The role of ABC transporters in drug resistance, metabolism and toxicity. Curr. Drug Deliv. 2004, 1, 27-42. [CrossRef] [PubMed]
    • (2004) Curr. Drug Deliv. , vol.1 , pp. 27-42
    • Glavinas, H.1    Krajcsi, P.2    Cserepes, J.3    Sarkadi, B.4
  • 114
    • 23044484221 scopus 로고    scopus 로고
    • Expression profiling of ABC transporters in a drug-resistant breast cancer cell line using AmpArray
    • CrossRef, PubMed
    • Liu, Y.; Peng, H.; Zhang, J.-T. Expression profiling of ABC transporters in a drug-resistant breast cancer cell line using AmpArray. Mol. Pharmacol. 2005, 68, 430-438. [CrossRef] [PubMed]
    • (2005) Mol. Pharmacol. , vol.68 , pp. 430-438
    • Liu, Y.1    Peng, H.2    Zhang, J.-T.3
  • 115
    • 33746742363 scopus 로고    scopus 로고
    • Gene expression profiling of ATP-binding cassette (ABC) transporters as a predictor of the pathologic response to neoadjuvant chemotherapy in breast cancer patients
    • CrossRef, PubMed
    • Park, S.; Shimizu, C.; Shimoyama, T.; Takeda, M.; Ando, M.; Kohno, T.; Katsumata, N.; Kang, Y.-K.; Nishio, K.; Fujiwara, Y. Gene expression profiling of ATP-binding cassette (ABC) transporters as a predictor of the pathologic response to neoadjuvant chemotherapy in breast cancer patients. Breast Cancer Res. Treat. 2006, 99, 9-17. [CrossRef] [PubMed]
    • (2006) Breast Cancer Res. Treat. , vol.99 , pp. 9-17
    • Park, S.1    Shimizu, C.2    Shimoyama, T.3    Takeda, M.4    Ando, M.5    Kohno, T.6    Katsumata, N.7    Kang, Y.-K.8    Nishio, K.9    Fujiwara, Y.10
  • 117
    • 0026504102 scopus 로고
    • Quercetin, a bioflavonoid, inhibits the increase of human multidrug resistance gene (MDR1) expression caused by arsenite
    • CrossRef
    • Kioka, N.; Hosokawa, N.; Komano, T.; Hirayoshi, K.; Nagate, K.; Ueda, K. Quercetin, a bioflavonoid, inhibits the increase of human multidrug resistance gene (MDR1) expression caused by arsenite. FEBS Lett. 1992, 301, 307-309. [CrossRef]
    • (1992) FEBS Lett. , vol.301 , pp. 307-309
    • Kioka, N.1    Hosokawa, N.2    Komano, T.3    Hirayoshi, K.4    Nagate, K.5    Ueda, K.6
  • 118
    • 21344436855 scopus 로고    scopus 로고
    • Restorative effect of quercetin on subcellular distribution of daunorubicin in multidrug resistant leukemia cell lines K562/ADM and HL-60/ADM
    • Cai, X.; Chen, F.; Han, J.; Gu, C.; Zhong, H.; Ouyang, R. Restorative effect of quercetin on subcellular distribution of daunorubicin in multidrug resistant leukemia cell lines K562/ADM and HL-60/ADM. Chin. J. Cancer 2004, 23, 1611-1615.
    • (2004) Chin. J. Cancer , vol.23 , pp. 1611-1615
    • Cai, X.1    Chen, F.2    Han, J.3    Gu, C.4    Zhong, H.5    Ouyang, R.6
  • 119
    • 33750566572 scopus 로고    scopus 로고
    • Reversal of multidrug resistance of HL-60 adriamycin resistant leukemia cell line by quercetin and its mechanisms
    • Cai, X.; Chen, F.; Han, J.; Gu, C.; Zhong, H.; Teng, Y.; Ouyang, R. Reversal of multidrug resistance of HL-60 adriamycin resistant leukemia cell line by quercetin and its mechanisms. Chin. J. Oncol. 2005, 27, 326-329.
    • (2005) Chin. J. Oncol. , vol.27 , pp. 326-329
    • Cai, X.1    Chen, F.2    Han, J.3    Gu, C.4    Zhong, H.5    Teng, Y.6    Ouyang, R.7
  • 120
    • 23844455227 scopus 로고    scopus 로고
    • Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR
    • CrossRef, PubMed
    • Tang, X.-Q.; Bi, H.; Feng, J.-Q.; Cao, J.-G. Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR. Acta Pharmacol. Sin. 2005, 26, 1009-1016. [CrossRef] [PubMed]
    • (2005) Acta Pharmacol. Sin. , vol.26 , pp. 1009-1016
    • Tang, X.-Q.1    Bi, H.2    Feng, J.-Q.3    Cao, J.-G.4
  • 121
    • 67249106291 scopus 로고    scopus 로고
    • Coadministration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells
    • CrossRef, PubMed
    • Ganta, S.; Amiji, M. Coadministration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells. Mol. Pharm. 2009, 6, 928-939. [CrossRef] [PubMed]
    • (2009) Mol. Pharm. , vol.6 , pp. 928-939
    • Ganta, S.1    Amiji, M.2
  • 122
    • 78149275673 scopus 로고    scopus 로고
    • MicroRNA expression profile of MCF-7 human breast cancer cells and the effect of green tea polyphenon-60
    • Fix, L.N.; Shah, M.; Efferth, T.; Farwell, M.A.; Zhang, B. MicroRNA expression profile of MCF-7 human breast cancer cells and the effect of green tea polyphenon-60. Cancer Genom. Proteom. 2010, 7, 261-277.
    • (2010) Cancer Genom. Proteom. , vol.7 , pp. 261-277
    • Fix, L.N.1    Shah, M.2    Efferth, T.3    Farwell, M.A.4    Zhang, B.5
  • 123
    • 81855224576 scopus 로고    scopus 로고
    • MicroRNAs en route to the clinic: Progress in validating and targeting microRNAs for cancer therapy
    • CrossRef, PubMed
    • Kasinski, A.L.; Slack, F.J. MicroRNAs en route to the clinic: Progress in validating and targeting microRNAs for cancer therapy. Nat. Rev. Cancer 2011, 11, 849-864. [CrossRef] [PubMed]
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 849-864
    • Kasinski, A.L.1    Slack, F.J.2
  • 124
    • 56449092072 scopus 로고    scopus 로고
    • MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1
    • CrossRef, PubMed
    • Miller, T.E.; Ghoshal, K.; Ramaswamy, B.; Roy, S.; Datta, J.; Shapiro, C.L.; Jacob, S.; Majumder, S. MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1. J. Biol. Chem. 2008, 283, 29897-29903. [CrossRef] [PubMed]
    • (2008) J. Biol. Chem. , vol.283 , pp. 29897-29903
    • Miller, T.E.1    Ghoshal, K.2    Ramaswamy, B.3    Roy, S.4    Datta, J.5    Shapiro, C.L.6    Jacob, S.7    Majumder, S.8
  • 125
    • 51049104524 scopus 로고    scopus 로고
    • Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin
    • CrossRef, PubMed
    • Kovalchuk, O.; Filkowski, J.; Meservy, J.; Ilnytskyy, Y.; Tryndyak, V.P.; Vasyl’F, C.; Pogribny, I.P. Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Mol. Cancer Ther. 2008, 7, 2152-2159. [CrossRef] [PubMed]
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 2152-2159
    • Kovalchuk, O.1    Filkowski, J.2    Meservy, J.3    Ilnytskyy, Y.4    Tryndyak, V.P.5    Vasyl’, F.C.6    Pogribny, I.P.7
  • 127
  • 128
    • 34548565806 scopus 로고    scopus 로고
    • Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin
    • CrossRef, PubMed
    • Hurteau, G.J.; Carlson, J.A.; Spivack, S.D.; Brock, G.J. Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin. Cancer Res. 2007, 67, 7972-7976. [CrossRef] [PubMed]
    • (2007) Cancer Res. , vol.67 , pp. 7972-7976
    • Hurteau, G.J.1    Carlson, J.A.2    Spivack, S.D.3    Brock, G.J.4
  • 129
    • 69349087756 scopus 로고    scopus 로고
    • miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy
    • CrossRef, PubMed
    • Adam, L.; Zhong, M.; Choi, W.; Qi, W.; Nicoloso, M.; Arora, A.; Calin, G.; Wang, H.; Siefker-Radtke, A.; McConkey, D. miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy. Clin. Cancer Res. 2009, 15, 5060-5072. [CrossRef] [PubMed]
    • (2009) Clin. Cancer Res. , vol.15 , pp. 5060-5072
    • Adam, L.1    Zhong, M.2    Choi, W.3    Qi, W.4    Nicoloso, M.5    Arora, A.6    Calin, G.7    Wang, H.8    Siefker-Radtke, A.9    McConkey, D.10
  • 130
    • 84925390465 scopus 로고    scopus 로고
    • Combination of Matrine and Sorafenib Decreases the Aggressive Phenotypes of Hepatocellular Carcinoma Cells
    • CrossRef, PubMed
    • Lin, Y.; Lin, L.; Jin, Y.; Zhang, Y.; Wang, D.; Tan, Y.; Zheng, C. Combination of Matrine and Sorafenib Decreases the Aggressive Phenotypes of Hepatocellular Carcinoma Cells. Chemotherapy 2014, 60, 112-118. [CrossRef] [PubMed]
    • (2014) Chemotherapy , vol.60 , pp. 112-118
    • Lin, Y.1    Lin, L.2    Jin, Y.3    Zhang, Y.4    Wang, D.5    Tan, Y.6    Zheng, C.7
  • 131
    • 84946411752 scopus 로고    scopus 로고
    • Matrine alters microRNA expression profiles in SGC-7901 human gastric cancer cells
    • CrossRef, PubMed
    • Li, H.; Xie, S.; Liu, X.;Wu, H.; Lin, X.; Gu, J.;Wang, H.; Duan, Y. Matrine alters microRNA expression profiles in SGC-7901 human gastric cancer cells. Oncol. Rep. 2014, 32, 2118-2126. [CrossRef] [PubMed]
    • (2014) Oncol. Rep. , vol.32 , pp. 2118-2126
    • Li, H.1    Xie, S.2    Liu, X.3    Wu, H.4    Lin, X.5    Gu, J.6    Wang, H.7    Duan, Y.8
  • 132
    • 84940554633 scopus 로고    scopus 로고
    • Oxymatrine suppresses proliferation and facilitates apoptosis of human ovarian cancer cells through upregulating microRNA-29b and downregulating matrix metalloproteinase-2 expression
    • CrossRef, PubMed
    • Li, J.; Jiang, K.; Zhao, F. Oxymatrine suppresses proliferation and facilitates apoptosis of human ovarian cancer cells through upregulating microRNA-29b and downregulating matrix metalloproteinase-2 expression. Mol. Med. Rep. 2015, 12, 5369-5374. [CrossRef] [PubMed]
    • (2015) Mol. Med. Rep. , vol.12 , pp. 5369-5374
    • Li, J.1    Jiang, K.2    Zhao, F.3
  • 133
    • 84907087913 scopus 로고    scopus 로고
    • MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin
    • CrossRef, PubMed
    • Wang, Z.; Wang, N.; Liu, P.; Chen, Q.; Situ, H.; Xie, T.; Zhang, J.; Peng, C.; Lin, Y.; Chen, J. MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin. Oncotarget 2014, 5, 7013-7026. [CrossRef] [PubMed]
    • (2014) Oncotarget , vol.5 , pp. 7013-7026
    • Wang, Z.1    Wang, N.2    Liu, P.3    Chen, Q.4    Situ, H.5    Xie, T.6    Zhang, J.7    Peng, C.8    Lin, Y.9    Chen, J.10
  • 134
    • 84875320111 scopus 로고    scopus 로고
    • Molecular mechanism of indirubin-30-monoxime and Matrine in the reversal of paclitaxel resistance in NCI-H520/TAX25 cell line
    • PubMed
    • Luo, S.; Deng, W.; Wang, X.; Lü, H.; Han, L.; Chen, B.; Chen, X.; Li, N. Molecular mechanism of indirubin-30-monoxime and Matrine in the reversal of paclitaxel resistance in NCI-H520/TAX25 cell line. Chin. Med. J. 2013, 126, 925-929. [PubMed]
    • (2013) Chin. Med. J. , vol.126 , pp. 925-929
    • Luo, S.1    Deng, W.2    Wang, X.3    Lü, H.4    Han, L.5    Chen, B.6    Chen, X.7    Li, N.8
  • 135
    • 0036118319 scopus 로고    scopus 로고
    • Apoptosis and chemoresistance in transgenic cancer models
    • CrossRef, PubMed
    • Schmitt, C.A.; Lowe, S.W. Apoptosis and chemoresistance in transgenic cancer models. J. Mol. Med. 2002, 80, 137-146. [CrossRef] [PubMed]
    • (2002) J. Mol. Med. , vol.80 , pp. 137-146
    • Schmitt, C.A.1    Lowe, S.W.2


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