Rhamnetin and cirsiliol induce radiosensitization and inhibition of epithelial-mesenchymal transition (EMT) by miR-34a-mediated suppression of Notch-1 expression in non-small cell lung cancer cell lines

Journal of Biological Chemistry

Volumn 288, Issue 38, 2013, Pages 27343-27357

  Kang, JiHoon ^a   Kim, EunGi ^a   Kim, Wanyeon ^a   Seong, Ki Moon ^b   Youn, HyeSook ^c   Kim, Jung Woo ^d   Kim, Joon ^e   Youn, Buhyun ^a  

^a Pusan National University   (South Korea)

^b Korea Hydro & Nuclear Power Co   (South Korea)

^c Sejong University   (South Korea)

^d PaiChai University   (South Korea)

^e Korea University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

EPITHELIAL-MESENCHYMAL TRANSITION; INHIBITION EFFECT; NON SMALL CELL LUNG CANCER; PHARMACOLOGICAL PROPERTIES; RADIATION-INDUCED; RADIO-SENSITIZATION; SIGNALING PATHWAYS; THERAPEUTIC DRUGS;

BIOLOGICAL ORGANS; CELL CULTURE; CELL DEATH; CELL PROLIFERATION; DIAGNOSIS; IRRADIATION; MAMMALS; RADIOTHERAPY; RNA; TUMORS;

RADIATION;

CIRSILIOL; MICRORNA 34A; NOTCH1 RECEPTOR; PROTEIN P53; RHAMNETIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CANCER RADIOTHERAPY; CELL FATE; CELL PROLIFERATION; CELL SURVIVAL; CHEMORADIOTHERAPY; CONTROLLED STUDY; DOWN REGULATION; DRUG SCREENING; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG NON SMALL CELL CANCER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RADIATION DOSE; RADIOSENSITIVITY; RADIOSENSITIZATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TUMOR VOLUME; TUMOR XENOGRAFT;

CANCER THERAPY; CIRSILIOL; EMT; LUNG CANCER; MIR-34A; NATURAL PRODUCTS; NOTCH-1; RADIATION BIOLOGY; RADIOSENSITIZATION; RHAMNETIN;

ANIMALS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL PROLIFERATION; EPITHELIAL-MESENCHYMAL TRANSITION; FLAVONES; GAMMA RAYS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; NF-KAPPA B; QUERCETIN; RADIATION TOLERANCE; RECEPTOR, NOTCH1; RNA, NEOPLASM; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84884567357     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.490482     Document Type: Article

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