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Volumn 35, Issue 6, 2014, Pages 5111-5119

Anti-tumor activities of matrine and oxymatrine: Literature review

Author keywords

Anticancer activity; Matrine; Molecular mechanism; Oxymatrine

Indexed keywords

MATRINE; OXYMATRINE;

EID: 84904719739     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-1680-z     Document Type: Review
Times cited : (208)

References (95)
  • 1
    • 84875962976 scopus 로고    scopus 로고
    • Inhibitory effects of curcumin on gastric cancer cells: A proteomic study of molecular targets
    • Cai XZ, Huang WY, Qiao Y, Du SY, Chen Y, Chen D, et al. Inhibitory effects of curcumin on gastric cancer cells: a proteomic study of molecular targets. Phytomedicine. 2013;20:495-505.
    • (2013) Phytomedicine , vol.20 , pp. 495-505
    • Cai, X.Z.1    Huang, W.Y.2    Qiao, Y.3    Du, S.Y.4    Chen, Y.5    Chen, D.6
  • 2
    • 74649083195 scopus 로고    scopus 로고
    • Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma
    • Bishayee A, Politis T, Darvesh AS. Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma. Cancer Treat Rev. 2010;36:43-53.
    • (2010) Cancer Treat Rev , vol.36 , pp. 43-53
    • Bishayee, A.1    Politis, T.2    Darvesh, A.S.3
  • 3
    • 84879448340 scopus 로고    scopus 로고
    • Curcumin induces apoptosis in gallbladder carcinoma cell line GBC-SD cells
    • Liu TY, Tan ZJ, Jiang L, Gu JF, Wu XS, Cao Y, et al. Curcumin induces apoptosis in gallbladder carcinoma cell line GBC-SD cells. Cancer Cell Int. 2013;13(1):64.
    • (2013) Cancer Cell Int , vol.13 , Issue.1 , pp. 64
    • Liu, T.Y.1    Tan, Z.J.2    Jiang, L.3    Gu, J.F.4    Wu, X.S.5    Cao, Y.6
  • 4
    • 80052099200 scopus 로고    scopus 로고
    • Curcumin inhibits the migration and invasion of mouse hepatoma Hca-F cells through down-regulating caveolin-1 expression and epidermal growth factor receptor signaling
    • Wang S, Yu S, Shi W, Ge L, Yu X, Fan J, et al. Curcumin inhibits the migration and invasion of mouse hepatoma Hca-F cells through down-regulating caveolin-1 expression and epidermal growth factor receptor signaling. IUBMB Life. 2011;63(9):775-82.
    • (2011) IUBMB Life , vol.63 , Issue.9 , pp. 775-782
    • Wang, S.1    Yu, S.2    Shi, W.3    Ge, L.4    Yu, X.5    Fan, J.6
  • 5
    • 65449167684 scopus 로고    scopus 로고
    • Lupeol inhibits proliferation of human prostate cancer cells by targeting beta-catenin signaling
    • Saleem M, Murtaza I, Tarapore RS, Suh Y, Adhami VM, Johnson JJ, et al. Lupeol inhibits proliferation of human prostate cancer cells by targeting beta-catenin signaling. Carcinogenesis. 2009;30(5):808-17.
    • (2009) Carcinogenesis , vol.30 , Issue.5 , pp. 808-817
    • Saleem, M.1    Murtaza, I.2    Tarapore, R.S.3    Suh, Y.4    Adhami, V.M.5    Johnson, J.J.6
  • 7
    • 84863090326 scopus 로고    scopus 로고
    • Matrine- and oxymatrine-imprinted monodisperse polymers prepared by precipitation polymerization and their applications for the selective extraction of matrine-type alkaloids from Sophora flavescens Aiton
    • Funaya N, Haginaka J. Matrine- and oxymatrine-imprinted monodisperse polymers prepared by precipitation polymerization and their applications for the selective extraction of matrine-type alkaloids from Sophora flavescens Aiton. J Chromatogr A. 2012;1248:18-23.
    • (2012) J Chromatogr A , vol.1248 , pp. 18-23
    • Funaya, N.1    Haginaka, J.2
  • 8
    • 0037264313 scopus 로고    scopus 로고
    • Preparative separation and determination of matrine from the Chinese medicinal plant Sophora flavescens Ait by molecularly imprinted solid-phase extraction
    • DOI 10.1007/s00216-002-1675-2
    • Lai JP, He XW, Jiang Y, Chen F. Preparative separation and determination of matrine from the Chinese medicinal plant Sophora flavescens Ait by molecularly imprinted solid-phase extraction. Anal Bioanal Chem. 2003;375:264-9. (Pubitemid 41201303)
    • (2003) Analytical and Bioanalytical Chemistry , vol.375 , Issue.2 , pp. 264-269
    • Lai, J.-P.1    He, X.-W.2    Jiang, Y.3    Chen, F.4
  • 9
    • 34247376897 scopus 로고    scopus 로고
    • Effect of matrine on the expression of substance P receptor and inflammatory cytokines production in human skin keratinocytes and fibroblasts
    • DOI 10.1016/j.intimp.2007.02.003, PII S1567576907000513
    • Liu JY, Hu JH, Zhu QG, Li FQ, Wang J, Sun HJ. Effect of matrine on the expression of substance P receptor and inflammatory cytokines production in human skin keratinocytes and fibroblasts. Int Immunopharmacol. 2007;7:816-23. (Pubitemid 46635279)
    • (2007) International Immunopharmacology , vol.7 , Issue.6 , pp. 816-823
    • Liu, J.-Y.1    Hu, J.-H.2    Zhu, Q.-G.3    Li, F.-Q.4    Wang, J.5    Sun, H.-J.6
  • 10
    • 67649985735 scopus 로고    scopus 로고
    • Separation and mechanism elucidation for six structure-like matrine-type alkaloids by micellar liquid chromatography
    • Sun J, Mao J, Liu X, Wang Y, Sun Y, He Z. Separation and mechanism elucidation for six structure-like matrine-type alkaloids by micellar liquid chromatography. J Sep Sci. 2009;32:2043-50.
    • (2009) J Sep Sci , vol.32 , pp. 2043-2050
    • Sun, J.1    Mao, J.2    Liu, X.3    Wang, Y.4    Sun, Y.5    He, Z.6
  • 11
    • 84895095291 scopus 로고    scopus 로고
    • Oxymatrine prevents NF-kappaB nuclear translocation and ameliorates acute intestinal inflammation
    • Guzman JR, Koo JS, Goldsmith JR, Muhlbauer M, Narula A, Jobin C. Oxymatrine prevents NF-kappaB nuclear translocation and ameliorates acute intestinal inflammation. Sci Rep. 2013;3:1629.
    • (2013) Sci Rep , vol.3 , pp. 1629
    • Guzman, J.R.1    Koo, J.S.2    Goldsmith, J.R.3    Muhlbauer, M.4    Narula, A.5    Jobin, C.6
  • 12
    • 78649637007 scopus 로고    scopus 로고
    • Antiarrhythmic effects and ionic mechanisms of oxymatrine from Sophora flavescens
    • Cao YG, Jing S, Li L, Gao JQ, Shen ZY, Liu Y, et al. Antiarrhythmic effects and ionic mechanisms of oxymatrine from Sophora flavescens. Phytother Res. 2010;24:1844-9.
    • (2010) Phytother Res , vol.24 , pp. 1844-1849
    • Cao, Y.G.1    Jing, S.2    Li, L.3    Gao, J.Q.4    Shen, Z.Y.5    Liu, Y.6
  • 13
    • 84866923865 scopus 로고    scopus 로고
    • Antiviral effect of matrine against human enterovirus 71
    • Yang Y, Xiu J, Zhang X, Zhang L, Yan K, Qin C, et al. Antiviral effect of matrine against human enterovirus 71. Molecules. 2012;17:10370-6.
    • (2012) Molecules , vol.17 , pp. 10370-10376
    • Yang, Y.1    Xiu, J.2    Zhang, X.3    Zhang, L.4    Yan, K.5    Qin, C.6
  • 14
    • 84867694572 scopus 로고    scopus 로고
    • Oxymatrine liposome attenuates hepatic fibrosis via targeting hepatic stellate cells
    • Chai NL, Fu Q, Shi H, Cai CH, Wan J, Xu SP, et al. Oxymatrine liposome attenuates hepatic fibrosis via targeting hepatic stellate cells. World J Gastroenterol. 2012;18:4199-206.
    • (2012) World J Gastroenterol , vol.18 , pp. 4199-4206
    • Chai, N.L.1    Fu, Q.2    Shi, H.3    Cai, C.H.4    Wan, J.5    Xu, S.P.6
  • 15
    • 59449108833 scopus 로고    scopus 로고
    • Efficacy and mechanisms of action of traditional Chinese medicines for treating asthma and allergy
    • quiz 7-8
    • Li XM, Brown L. Efficacy and mechanisms of action of traditional Chinese medicines for treating asthma and allergy. J Allergy Clin Immunol. 2009;123:297-306. quiz 7-8.
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 297-306
    • Li, X.M.1    Brown, L.2
  • 16
    • 77957844279 scopus 로고    scopus 로고
    • The analgesic effect and mechanism of the combination of sodium ferulate and oxymatrine
    • Liu H, Sun Y, Gao Y, Chen F, Xu M, Liu Z. The analgesic effect and mechanism of the combination of sodium ferulate and oxymatrine. Neurochem Res. 2010;35:1368-75.
    • (2010) Neurochem Res , vol.35 , pp. 1368-1375
    • Liu, H.1    Sun, Y.2    Gao, Y.3    Chen, F.4    Xu, M.5    Liu, Z.6
  • 17
    • 84876411579 scopus 로고    scopus 로고
    • Matrine suppresses expression of adhesion molecules and chemokines as a mechanism underlying its therapeutic effect in CNS autoimmunity
    • Kan QC, Zhu L, Liu N, Zhang GX. Matrine suppresses expression of adhesion molecules and chemokines as a mechanism underlying its therapeutic effect in CNS autoimmunity. Immunol Res. 2013;56:189-96.
    • (2013) Immunol Res , vol.56 , pp. 189-196
    • Kan, Q.C.1    Zhu, L.2    Liu, N.3    Zhang, G.X.4
  • 18
    • 79955838925 scopus 로고    scopus 로고
    • Autophagy is involved in anticancer effects of matrine on SGC-7901 human gastric cancer cells
    • Zhang J, Li Y, Chen X, Liu T, Chen Y, He W, et al. Autophagy is involved in anticancer effects of matrine on SGC-7901 human gastric cancer cells. Oncol Rep. 2011;26:115-24.
    • (2011) Oncol Rep , vol.26 , pp. 115-124
    • Zhang, J.1    Li, Y.2    Chen, X.3    Liu, T.4    Chen, Y.5    He, W.6
  • 19
    • 70449533764 scopus 로고    scopus 로고
    • Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration
    • Zhang Y, Zhang H, Yu P, Liu Q, Liu K, Duan H, et al. Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration. Cytotechnology. 2009;59:191-200.
    • (2009) Cytotechnology , vol.59 , pp. 191-200
    • Zhang, Y.1    Zhang, H.2    Yu, P.3    Liu, Q.4    Liu, K.5    Duan, H.6
  • 20
    • 84864090039 scopus 로고    scopus 로고
    • Matrine inhibits breast cancer growth via miR-21/PTEN/Akt pathway in MCF-7 cells
    • Li LQ, Li XL, Wang L, Du WJ, Guo R, Liang HH, et al. Matrine inhibits breast cancer growth via miR-21/PTEN/Akt pathway in MCF-7 cells. Cell Physiol Biochem. 2012;30:631-41.
    • (2012) Cell Physiol Biochem , vol.30 , pp. 631-641
    • Li, L.Q.1    Li, X.L.2    Wang, L.3    Du, W.J.4    Guo, R.5    Liang, H.H.6
  • 21
    • 77957557122 scopus 로고    scopus 로고
    • Antitumor effect ofmatrine in human hepatoma G2 cells by inducing apoptosis and autophagy
    • Zhang JQ, Li YM, Liu T, He WT, Chen YT, Chen XH, et al. Antitumor effect ofmatrine in human hepatoma G2 cells by inducing apoptosis and autophagy. World J Gastroenterol. 2010;16:4281-90.
    • (2010) World J Gastroenterol , vol.16 , pp. 4281-4290
    • Zhang, J.Q.1    Li, Y.M.2    Liu, T.3    He, W.T.4    Chen, Y.T.5    Chen, X.H.6
  • 22
    • 84879665522 scopus 로고    scopus 로고
    • Antiangiogenic effects of oxymatrine on pancreatic cancer by inhibition of the NF-kappaB-mediated VEGF signaling pathway
    • Chen H, Zhang J, Luo J, Lai F, Wang Z, Tong H, et al. Antiangiogenic effects of oxymatrine on pancreatic cancer by inhibition of the NF-kappaB-mediated VEGF signaling pathway. Oncol Rep. 2013;30:589-95.
    • (2013) Oncol Rep , vol.30 , pp. 589-595
    • Chen, H.1    Zhang, J.2    Luo, J.3    Lai, F.4    Wang, Z.5    Tong, H.6
  • 23
    • 84881165246 scopus 로고    scopus 로고
    • Matrine activates PTEN to induce growth inhibition and apoptosis in V600EBRAF harboring melanoma cells
    • Jin H, Sun Y, Wang S, Cheng X. Matrine activates PTEN to induce growth inhibition and apoptosis in V600EBRAF harboring melanoma cells. Int J Mol Sci. 2013;14:16040-57.
    • (2013) Int J Mol Sci , vol.14 , pp. 16040-16057
    • Jin, H.1    Sun, Y.2    Wang, S.3    Cheng, X.4
  • 24
    • 84867299726 scopus 로고    scopus 로고
    • Matrine induces apoptosis in human acute myeloid leukemia cells via the mitochondrial pathway and Akt inactivation
    • Zhang S, Zhang Y, Zhuang Y, Wang J, Ye J, Zhang S, et al. Matrine induces apoptosis in human acute myeloid leukemia cells via the mitochondrial pathway and Akt inactivation. PloS One. 2012;7:e46853.
    • (2012) PloS One , vol.7
    • Zhang, S.1    Zhang, Y.2    Zhuang, Y.3    Wang, J.4    Ye, J.5    Zhang, S.6
  • 26
    • 84881481643 scopus 로고    scopus 로고
    • Matrine inhibited the growth of rat osteosarcoma UMR-108 cells by inducing apoptosis in a mitochondrial-caspase- dependent pathway
    • Yan F, Liu Y, Wang W. Matrine inhibited the growth of rat osteosarcoma UMR-108 cells by inducing apoptosis in a mitochondrial-caspase- dependent pathway. Tumour Biol. 2013;34:2135-40.
    • (2013) Tumour Biol , vol.34 , pp. 2135-2140
    • Yan, F.1    Liu, Y.2    Wang, W.3
  • 27
    • 51349164386 scopus 로고    scopus 로고
    • Multitargeted therapy of cancer by silymarin
    • Ramasamy K, Agarwal R. Multitargeted therapy of cancer by silymarin. Cancer Lett. 2008;269:352-62.
    • (2008) Cancer Lett , vol.269 , pp. 352-362
    • Ramasamy, K.1    Agarwal, R.2
  • 28
    • 84856765126 scopus 로고    scopus 로고
    • Matrine induces caspase-dependent apoptosis in human osteosarcoma cells in vitro and in vivo through the upregulation of Bax and Fas/FasL and downregulation of Bcl-2
    • Liang CZ, Zhang JK, Shi Z, Liu B, Shen CQ, Tao HM. Matrine induces caspase-dependent apoptosis in human osteosarcoma cells in vitro and in vivo through the upregulation of Bax and Fas/FasL and downregulation of Bcl-2. Cancer Chemother Pharmacol. 2012;69:317-31.
    • (2012) Cancer Chemother Pharmacol , vol.69 , pp. 317-331
    • Liang, C.Z.1    Zhang, J.K.2    Shi, Z.3    Liu, B.4    Shen, C.Q.5    Tao, H.M.6
  • 29
    • 84864297885 scopus 로고    scopus 로고
    • Effects of matrine on proliferation and apoptosis of cultured retinoblastoma cells
    • Zhao B, Li B, Bai S, Shen L, Ren R, Jonas JB, et al. Effects of matrine on proliferation and apoptosis of cultured retinoblastoma cells. Graefes Arch Clin Exp Ophthalmol. 2012;250:897-905.
    • (2012) Graefes Arch Clin Exp Ophthalmol , vol.250 , pp. 897-905
    • Zhao, B.1    Li, B.2    Bai, S.3    Shen, L.4    Ren, R.5    Jonas, J.B.6
  • 30
    • 77953027498 scopus 로고    scopus 로고
    • Matrine inhibits 3 T3-L1 preadipocyte differentiation associated with suppression of ERK1/2 phosphorylation
    • Xing Y, Yan F, Liu Y, Liu Y, Zhao Y. Matrine inhibits 3 T3-L1 preadipocyte differentiation associated with suppression of ERK1/2 phosphorylation. Biochem Biophys Res Commun. 2010;396:691-5.
    • (2010) Biochem Biophys Res Commun , vol.396 , pp. 691-695
    • Xing, Y.1    Yan, F.2    Liu, Y.3    Liu, Y.4    Zhao, Y.5
  • 31
    • 79952780900 scopus 로고    scopus 로고
    • Matrine inhibits matrix metalloproteinase-9 expression and invasion of human hepatocellular carcinoma cells
    • Yu HB, Zhang HF, Li DY, Zhang X, Xue HZ, Zhao SH. Matrine inhibits matrix metalloproteinase-9 expression and invasion of human hepatocellular carcinoma cells. J Asian Nat Prod Res. 2011;13:242-50.
    • (2011) J Asian Nat Prod Res , vol.13 , pp. 242-250
    • Yu, H.B.1    Zhang, H.F.2    Li, D.Y.3    Zhang, X.4    Xue, H.Z.5    Zhao, S.H.6
  • 32
    • 79951584353 scopus 로고    scopus 로고
    • Oxymatrine inhibits hepatitis B infection with an advantage of overcoming drug-resistance
    • Wang YP, Zhao W, Xue R, Zhou ZX, Liu F, Han YX, et al. Oxymatrine inhibits hepatitis B infection with an advantage of overcoming drug-resistance. Antiviral Res. 2011;89:227-31.
    • (2011) Antiviral Res , vol.89 , pp. 227-231
    • Wang, Y.P.1    Zhao, W.2    Xue, R.3    Zhou, Z.X.4    Liu, F.5    Han, Y.X.6
  • 33
    • 84885471396 scopus 로고    scopus 로고
    • Meta-analysis: Therapeutic effect of transcatheter arterial chemoembolization combined with compound kushen injection in hepatocellular carcinoma
    • Sun Q, Ma W, Gao Y, Zheng W, Zhang B, Peng Y. Meta-analysis: therapeutic effect of transcatheter arterial chemoembolization combined with compound kushen injection in hepatocellular carcinoma. Afr J Tradit Complement Altern Med. 2012;9:178-88.
    • (2012) Afr J Tradit Complement Altern Med , vol.9 , pp. 178-188
    • Sun, Q.1    Ma, W.2    Gao, Y.3    Zheng, W.4    Zhang, B.5    Peng, Y.6
  • 35
    • 64249154146 scopus 로고    scopus 로고
    • Matrine induces apoptosis in gastric carcinoma cells via alteration of Fas/FasL and activation of caspase-3
    • Dai ZJ, Gao J, Ji ZZ, Wang XJ, Ren HT, Liu XX, et al. Matrine induces apoptosis in gastric carcinoma cells via alteration of Fas/FasL and activation of caspase-3. J Ethnopharmacol. 2009;123:91-6.
    • (2009) J Ethnopharmacol , vol.123 , pp. 91-96
    • Dai, Z.J.1    Gao, J.2    Ji, Z.Z.3    Wang, X.J.4    Ren, H.T.5    Liu, X.X.6
  • 36
    • 70449534614 scopus 로고    scopus 로고
    • Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NFkappaB signaling
    • Yu P, Liu Q, Liu K, Yagasaki K, Wu E, Zhang G. Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NFkappaB signaling. Cytotechnology. 2009;59:219-29.
    • (2009) Cytotechnology , vol.59 , pp. 219-229
    • Yu, P.1    Liu, Q.2    Liu, K.3    Yagasaki, K.4    Wu, E.5    Zhang, G.6
  • 38
    • 16344395310 scopus 로고    scopus 로고
    • Experimental study of the killing effects of oxymatrine on human colon cancer cell line SW1116
    • DOI 10.1111/j.1443-9573.2005.00181.x
    • Zou J, Ran ZH, Xu Q, Xiao SD. Experimental study of the killing effects of oxymatrine on human colon cancer cell line SW1116. Chin J Dig Dis. 2005;6:15-20. (Pubitemid 40467729)
    • (2005) Chinese Journal of Digestive Diseases , vol.6 , Issue.1 , pp. 15-20
    • Zou, J.1    Ran, Z.H.2    Xu, Q.3    Xiao, S.D.4
  • 39
    • 61449105025 scopus 로고    scopus 로고
    • Matrine induces programmed cell death and regulates expression of relevant genes based on PCR array analysis in C6 glioma cells
    • Zhang S, Qi J, Sun L, Cheng B, Pan S, Zhou M, et al. Matrine induces programmed cell death and regulates expression of relevant genes based on PCR array analysis in C6 glioma cells. Mol Biol Rep. 2009;36:791-9.
    • (2009) Mol Biol Rep , vol.36 , pp. 791-799
    • Zhang, S.1    Qi, J.2    Sun, L.3    Cheng, B.4    Pan, S.5    Zhou, M.6
  • 40
    • 79959641621 scopus 로고    scopus 로고
    • Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome c
    • Ling Q, Xu X, Wei X, Wang W, Zhou B, Wang B, et al. Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome c. J Exp Clin Cancer Res. 2011;30:66.
    • (2011) J Exp Clin Cancer Res , vol.30 , pp. 66
    • Ling, Q.1    Xu, X.2    Wei, X.3    Wang, W.4    Zhou, B.5    Wang, B.6
  • 41
    • 33744899623 scopus 로고    scopus 로고
    • Matrine-induced apoptosis in leukemia U937 cells-involvement of caspases activation and MAPK-independent pathways
    • Liu XS, Jiang JK, Jiao XY, Wu YE, Lin JH. Matrine-induced apoptosis in leukemia U937 cells-involvement of caspases activation and MAPK-independent pathways. Planta Med. 2006;72:501-6.
    • (2006) Planta Med , vol.72 , pp. 501-506
    • Liu, X.S.1    Jiang, J.K.2    Jiao, X.Y.3    Wu, Y.E.4    Lin, J.H.5
  • 42
    • 77957987817 scopus 로고    scopus 로고
    • Matrine inhibits proliferation and induces apoptosis of pancreatic cancer cells in vitro and in vivo
    • Liu TY, Song Y, Chen H, Pan SH, Sun XY. Matrine inhibits proliferation and induces apoptosis of pancreatic cancer cells in vitro and in vivo. Biol Pharm Bull. 2010;33:1740-5.
    • (2010) Biol Pharm Bull , vol.33 , pp. 1740-1745
    • Liu, T.Y.1    Song, Y.2    Chen, H.3    Pan, S.H.4    Sun, X.Y.5
  • 43
    • 41349091860 scopus 로고    scopus 로고
    • Anticancer effects of the Chinese medicine matrine on murine hepatocellular carcinoma cells
    • DOI 10.1055/s-2008-1034304
    • Ma L, Wen S, Zhan Y, He Y, Liu X, Jiang J. Anticancer effects of the Chinese medicine matrine on murine hepatocellular carcinoma cells. Planta Med. 2008;74:245-51. (Pubitemid 351449946)
    • (2008) Planta Medica , vol.74 , Issue.3 , pp. 245-251
    • Ma, L.1    Wen, S.2    Zhan, Y.3    He, Y.4    Liu, X.5    Jiang, J.6
  • 44
    • 84861577588 scopus 로고    scopus 로고
    • Synthesis, characterization and in vitro anti-tumor activities of matrine derivatives
    • Wang L, You Y, Wang S, Liu X, Liu B, Wang J, et al. Synthesis, characterization and in vitro anti-tumor activities of matrine derivatives. Bioorg Med Chem Lett. 2012;22(12):4100-2.
    • (2012) Bioorg Med Chem Lett , vol.22 , Issue.12 , pp. 4100-4102
    • Wang, L.1    You, Y.2    Wang, S.3    Liu, X.4    Liu, B.5    Wang, J.6
  • 45
    • 0041829414 scopus 로고    scopus 로고
    • A novel organoselenium compound induces cell cycle arrest and apoptosis in prostate cancer cell lines
    • DOI 10.1016/j.bbrc.2003.08.032
    • Shi C, Yu L, Yang F, Yan J, Zeng H. A novel organoselenium compound induces cell cycle arrest and apoptosis in prostate cancer cell lines. Biochem Biophys Res Commun. 2003;309:578-83. (Pubitemid 37083290)
    • (2003) Biochemical and Biophysical Research Communications , vol.309 , Issue.3 , pp. 578-583
    • Shi, C.1    Yu, L.2    Yang, F.3    Yan, J.4    Zeng, H.5
  • 46
    • 84904767322 scopus 로고    scopus 로고
    • Effect of Matrine on cell cycle and human telomerase reverse transcriptase of human salivary adenoid cystic carcinoma
    • Zhao JF, Xie GR, Li XM, Chen WT, Sun ML, Fang Z, et al. Effect of Matrine on cell cycle and human telomerase reverse transcriptase of human salivary adenoid cystic carcinoma. Hua Xi Kou Qiang Yi Xue Za Zhi. 2010;28:234-40.
    • (2010) Hua Xi Kou Qiang Yi Xue Za Zhi , vol.28 , pp. 234-240
    • Zhao, J.F.1    Xie, G.R.2    Li, X.M.3    Chen, W.T.4    Sun, M.L.5    Fang, Z.6
  • 47
    • 84861815153 scopus 로고    scopus 로고
    • Effects of matrine on proliferation and apoptosis in gallbladder carcinoma cells (GBC-SD)
    • Zhang Z, Wang X, Wu W, Wang J, Wang Y, Wu X, et al. Effects of matrine on proliferation and apoptosis in gallbladder carcinoma cells (GBC-SD). Phytother Res. 2012;26:932-7.
    • (2012) Phytother Res , vol.26 , pp. 932-937
    • Zhang, Z.1    Wang, X.2    Wu, W.3    Wang, J.4    Wang, Y.5    Wu, X.6
  • 48
    • 0034306996 scopus 로고    scopus 로고
    • The Rb/E2F pathway: Expanding roles and emerging paradigms
    • Harbour JW, Dean DC. The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev. 2000;14:2393-409.
    • (2000) Genes Dev , vol.14 , pp. 2393-2409
    • Harbour, J.W.1    Dean, D.C.2
  • 49
    • 33847136330 scopus 로고    scopus 로고
    • Matrine upregulates the cell cycle protein E2F-1 and triggers apoptosis via the mitochondrial pathway in K562 cells
    • DOI 10.1016/j.ejphar.2006.12.017, PII S0014299907000040
    • Jiang H, Hou C, Zhang S, Xie H, Zhou W, Jin Q, et al. Matrine upregulates the cell cycle protein E2F-1 and triggers apoptosis via the mitochondrial pathway in K562 cells. Eur J Pharmacol. 2007;559:98-108. (Pubitemid 46295409)
    • (2007) European Journal of Pharmacology , vol.559 , Issue.2-3 , pp. 98-108
    • Jiang, H.1    Hou, C.2    Zhang, S.3    Xie, H.4    Zhou, W.5    Jin, Q.6    Cheng, X.7    Qian, R.8    Zhang, X.9
  • 50
    • 0347601880 scopus 로고    scopus 로고
    • A decade of caspases
    • DOI 10.1038/sj.onc.1207107
    • Degterev A, Boyce M, Yuan J. A decade of caspases. Oncogene. 2003;22:8543-67. (Pubitemid 38028527)
    • (2003) Oncogene , vol.22 , Issue.53 REV. ISS. 7 , pp. 8543-8567
    • Degterev, A.1    Boyce, M.2    Yuan, J.3
  • 51
    • 79952635820 scopus 로고    scopus 로고
    • Measuring and modeling apoptosis in single cells
    • Spencer SL, Sorger PK. Measuring and modeling apoptosis in single cells. Cell. 2011;144:926-39.
    • (2011) Cell , vol.144 , pp. 926-939
    • Spencer, S.L.1    Sorger, P.K.2
  • 52
    • 84898923003 scopus 로고    scopus 로고
    • Oxymatrine induces mitochondria dependent apoptosis in human osteosarcoma MNNG/HOS cells through inhibition of PI3K/Akt pathway
    • doi:10.1007/s13277-013-1223-z
    • Zhang Y, Sun S, Chen J, Ren P, Hu Y, Cao Z, et al. Oxymatrine induces mitochondria dependent apoptosis in human osteosarcoma MNNG/HOS cells through inhibition of PI3K/Akt pathway. Tumour Biol. 2013. doi:10.1007/s13277-013-1223- z.
    • (2013) Tumour Biol
    • Zhang, Y.1    Sun, S.2    Chen, J.3    Ren, P.4    Hu, Y.5    Cao, Z.6
  • 53
    • 18244392443 scopus 로고    scopus 로고
    • Cell death independent of caspases: A review
    • DOI 10.1158/1078-0432.CCR-04-2223
    • Bröker LE, Kruyt FAE, Giaccone G. Cell death independent of caspases: a review. Clin Cancer Res. 2005;11:3155-62. (Pubitemid 40627860)
    • (2005) Clinical Cancer Research , vol.11 , Issue.9 , pp. 3155-3162
    • Broker, L.E.1    Kruyt, F.A.E.2    Giaccone, G.3
  • 55
    • 84885161115 scopus 로고    scopus 로고
    • Matrine induction of reactive oxygen species activates p38 leading to caspase-dependent cell apoptosis in non-small cell lung cancer cells
    • Tan CH, Qian XQ, Jia RD, Wu M, Liang ZQ. Matrine induction of reactive oxygen species activates p38 leading to caspase-dependent cell apoptosis in non-small cell lung cancer cells. Oncol Rep. 2013;30:2529-35.
    • (2013) Oncol Rep , vol.30 , pp. 2529-2535
    • Tan, C.H.1    Qian, X.Q.2    Jia, R.D.3    Wu, M.4    Liang, Z.Q.5
  • 56
    • 34248215651 scopus 로고    scopus 로고
    • Synergistic effect of oxymatrine and angiogenesis inhibitor NM-3 on modulating apoptosis in human gastric cancer cells
    • Song MQ, Zhu JS, Chen JL, Wang L, Da W, Zhu L, et al. Synergistic effect of oxymatrine and angiogenesis inhibitorNM-3 on modulating apoptosis in human gastric cancer cells. World J Gastroenterol. 2007;13:1788-93. (Pubitemid 46706010)
    • (2007) World Journal of Gastroenterology , vol.13 , Issue.12 , pp. 1788-1793
    • Song, M.-Q.1    Zhu, J.-S.2    Chen, J.-L.3    Wang, L.4    Da, W.5    Zhu, L.6    Zhang, W.-P.7
  • 57
    • 45749125270 scopus 로고    scopus 로고
    • Effects of oxymatrine on the apoptosis of human esophageal carcinoma Eca109 cell line and its mechanism
    • Jin Y, Hu J, Wang Q, Li Z, Chen Y. Effects of oxymatrine on the apoptosis of human esophageal carcinoma Eca109 cell line and its mechanism. J Huazhong Univ of Sci Technolog Med Sci. 2008;28:314-6.
    • (2008) J Huazhong Univ of Sci Technolog Med Sci , vol.28 , pp. 314-316
    • Jin, Y.1    Hu, J.2    Wang, Q.3    Li, Z.4    Chen, Y.5
  • 58
  • 59
    • 34347205690 scopus 로고    scopus 로고
    • Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1
    • Lee TH, Seng S, Sekine M, Hinton C, Fu Y, Avraham HK, et al. Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1. PLoS Med. 2007;4:e186.
    • (2007) PLoS Med , vol.4
    • Lee, T.H.1    Seng, S.2    Sekine, M.3    Hinton, C.4    Fu, Y.5    Avraham, H.K.6
  • 60
    • 11444250615 scopus 로고    scopus 로고
    • Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors
    • DOI 10.1016/j.canlet.2004.08.007, PII S0304383504006275
    • North S, Moenner M, Bikfalvi A. Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors. Cancer Lett. 2005;218:1-14. (Pubitemid 40082696)
    • (2005) Cancer Letters , vol.218 , Issue.1 , pp. 1-14
    • North, S.1    Moenner, M.2    Bikfalvi, A.3
  • 61
    • 84978320177 scopus 로고    scopus 로고
    • Anttumor effects of matrine on murine hepatocarcinoma cell line H22 and the mechanism
    • Qu F, Cui YR, Xu J. Anttumor effects of matrine on murine hepatocarcinoma cell line H22 and the mechanism. Anti-tumor Pharmacy (China). 2011;1:374-8.
    • (2011) Anti-tumor Pharmacy (China) , vol.1 , pp. 374-378
    • Qu, F.1    Cui, Y.R.2    Xu, J.3
  • 62
    • 68149117525 scopus 로고    scopus 로고
    • Analysis of VEGF, Flt-1, Flk-1, nestin and MMP-9 in relation to astrocytoma pathogenesis and progression
    • Hlobilkova A, Ehrmann J, Knizetova P, Krejci V, Kalita O, Kolar Z. Analysis of VEGF, Flt-1, Flk-1, nestin and MMP-9 in relation to astrocytoma pathogenesis and progression. Neoplasma. 2009;56:284-90.
    • (2009) Neoplasma , vol.56 , pp. 284-290
    • Hlobilkova, A.1    Ehrmann, J.2    Knizetova, P.3    Krejci, V.4    Kalita, O.5    Kolar, Z.6
  • 63
    • 77949425064 scopus 로고    scopus 로고
    • Melittin suppresses PMA-induced tumor cell invasion by inhibiting NF-kappaB and AP-1-dependent MMP-9 expression
    • Park JH, Jeong YJ, Park KK, Cho HJ, Chung IK, Min KS, et al. Melittin suppresses PMA-induced tumor cell invasion by inhibiting NF-kappaB and AP-1-dependent MMP-9 expression. Mol Cells. 2010;29:209-15.
    • (2010) Mol Cells , vol.29 , pp. 209-215
    • Park, J.H.1    Jeong, Y.J.2    Park, K.K.3    Cho, H.J.4    Chung, I.K.5    Min, K.S.6
  • 65
    • 77956618577 scopus 로고    scopus 로고
    • Tumorigenic and adhesive properties of heparanase
    • Levy-Adam F, Ilan N, Vlodavsky I. Tumorigenic and adhesive properties of heparanase. Semin Cancer Biol. 2010;20:153-60.
    • (2010) Semin Cancer Biol , vol.20 , pp. 153-160
    • Levy-Adam, F.1    Ilan, N.2    Vlodavsky, I.3
  • 66
    • 78149434361 scopus 로고    scopus 로고
    • Therapeutic effects ofmatrine on primary andmetastatic breast cancer
    • Li H, Tan G, Jiang X, Qiao H, Pan S, Jiang H, et al. Therapeutic effects ofmatrine on primary andmetastatic breast cancer. AmJ Chin Med. 2010;38:1115-30.
    • (2010) AmJ Chin Med , vol.38 , pp. 1115-1130
    • Li, H.1    Tan, G.2    Jiang, X.3    Qiao, H.4    Pan, S.5    Jiang, H.6
  • 68
    • 80052697287 scopus 로고    scopus 로고
    • The role of autophagy in cancer: Therapeutic implications
    • Yang ZJ, Chee CE, Huang S, Sinicrope FA. The role of autophagy in cancer: therapeutic implications. Mol Cancer Ther. 2011;10:1533-41.
    • (2011) Mol Cancer Ther , vol.10 , pp. 1533-1541
    • Yang, Z.J.1    Chee, C.E.2    Huang, S.3    Sinicrope, F.A.4
  • 70
    • 84872127937 scopus 로고    scopus 로고
    • Matrine, a novel autophagy inhibitor, blocks trafficking and the proteolytic activation of lysosomal proteases
    • Wang Z, Zhang J, Wang Y, Xing R, Yi C, Zhu H, et al. Matrine, a novel autophagy inhibitor, blocks trafficking and the proteolytic activation of lysosomal proteases. Carcinogenesis. 2013;34:128-38.
    • (2013) Carcinogenesis , vol.34 , pp. 128-138
    • Wang, Z.1    Zhang, J.2    Wang, Y.3    Xing, R.4    Yi, C.5    Zhu, H.6
  • 71
    • 34147095342 scopus 로고    scopus 로고
    • Protein composition of catalytically active human telomerase from immortal cells
    • DOI 10.1126/science.1138596
    • Cohen SB, Graham ME, Lovrecz GO, Bache N, Robinson PJ, Reddel RR. Protein composition of catalytically active human telomerase from immortal cells. Science. 2007;315:1850-3. (Pubitemid 46580145)
    • (2007) Science , vol.315 , Issue.5820 , pp. 1850-1853
    • Cohen, S.B.1    Graham, M.E.2    Lovrecz, G.O.3    Bache, N.4    Robinson, P.J.5    Reddel, R.R.6
  • 73
    • 84867897622 scopus 로고    scopus 로고
    • Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer
    • Liu HQ, Liu SL, Wang H, Xie XY, Chen XL, Zhang XM, et al. Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer. Diagn Pathol. 2012;7: 1-8.
    • (2012) Diagn Pathol , vol.7 , pp. 1-8
    • Liu, H.Q.1    Liu, S.L.2    Wang, H.3    Xie, X.Y.4    Chen, X.L.5    Zhang, X.M.6
  • 75
    • 34547489197 scopus 로고    scopus 로고
    • p27KIP1 and GATA-1 are potential downstream molecules in activin Ainduced differentiation and apoptosis pathways in CML cells
    • Fukuchi Y, Yamato K, Kawamura C, Ikeda Y, Kizaki M. p27KIP1 and GATA-1 are potential downstream molecules in activin Ainduced differentiation and apoptosis pathways in CML cells. Oncol Rep. 2006;16:1099-103.
    • (2006) Oncol Rep , vol.16 , pp. 1099-1103
    • Fukuchi, Y.1    Yamato, K.2    Kawamura, C.3    Ikeda, Y.4    Kizaki, M.5
  • 76
    • 51049095727 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance
    • Inoue N, Yahagi N, Yamamoto T, Ishikawa M, Watanabe K, Matsuzaka T, et al. Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance. J Biol Chem. 2008;283:21220-9.
    • (2008) J Biol Chem , vol.283 , pp. 21220-21229
    • Inoue, N.1    Yahagi, N.2    Yamamoto, T.3    Ishikawa, M.4    Watanabe, K.5    Matsuzaka, T.6
  • 77
    • 77958472044 scopus 로고    scopus 로고
    • P-Glycoprotein/MDR1 regulates Pokemon gene transcription through p53 expression in human breast cancer cells
    • He S, Liu F, Xie Z, Zu X, Xu W, Jiang Y. P-Glycoprotein/MDR1 regulates Pokemon gene transcription through p53 expression in human breast cancer cells. Int J Mol Sci. 2010;11:3309-51.
    • (2010) Int J Mol Sci , vol.11 , pp. 3309-3351
    • He, S.1    Liu, F.2    Xie, Z.3    Zu, X.4    Xu, W.5    Jiang, Y.6
  • 78
    • 77949371041 scopus 로고    scopus 로고
    • Perspectives of P-glycoprotein modulating agents in oncology and neurodegenerative diseases: Pharmaceutical, biological, and diagnostic potentials
    • Colabufo NA, Berardi F, Cantore M, ContinoM, Inglese C, Niso M, et al. Perspectives of P-glycoprotein modulating agents in oncology and neurodegenerative diseases: pharmaceutical, biological, and diagnostic potentials. J Med Chem. 2010;53:1883-97.
    • (2010) J Med Chem , vol.53 , pp. 1883-1897
    • Colabufo, N.A.1    Berardi, F.2    Cantore, M.3    Contino, M.4    Inglese, C.5    Niso, M.6
  • 79
    • 77954813506 scopus 로고    scopus 로고
    • Circumvention of multi-drug resistance of cancer cells by Chinese herbal medicines
    • Chai S, To KK, Lin G. Circumvention of multi-drug resistance of cancer cells by Chinese herbal medicines. Chin Med. 2010;5:26.
    • (2010) Chin Med , vol.5 , pp. 26
    • Chai, S.1    To, K.K.2    Lin, G.3
  • 80
    • 84904744638 scopus 로고    scopus 로고
    • Reversal effect of matrine on drug resistance of human nasopharyngeal carcinoma cell line
    • Zhang J, Tang AZ. Reversal effect of matrine on drug resistance of human nasopharyngeal carcinoma cell line. Zhong Yao Cai. 2012;35(12):1989-94.
    • (2012) Zhong Yao Cai , vol.35 , Issue.12 , pp. 1989-1994
    • Zhang, J.1    Tang, A.Z.2
  • 81
    • 77950794337 scopus 로고    scopus 로고
    • Survivin transcription is associated with P-glycoprotein/MDR1 overexpression in the multidrug resistance of MCF-7 breast cancer cells
    • Liu F, Liu SY, He SN, Xie ZH, Zu XY, Jiang YY. Survivin transcription is associated with P-glycoprotein/MDR1 overexpression in the multidrug resistance of MCF-7 breast cancer cells. Oncol Rep. 2010;23:1469-75.
    • (2010) Oncol Rep , vol.23 , pp. 1469-1475
    • Liu, F.1    Liu, S.Y.2    He, S.N.3    Xie, Z.H.4    Zu, X.Y.5    Jiang, Y.Y.6
  • 82
    • 84875320111 scopus 로고    scopus 로고
    • Molecular mechanism of indirubin-3?-monoxime and matrine in the reversal of paclitaxel resistance in NCI-H520/TAX25 cell line
    • Luo SX, Deng WY, Wang XF, Lu HF, Han LL, Chen BB, et al. Molecular mechanism of indirubin-3?-monoxime and matrine in the reversal of paclitaxel resistance in NCI-H520/TAX25 cell line. Chin Med J (Enql). 2013;126:925-9.
    • (2013) Chin Med J (Enql) , vol.126 , pp. 925-929
    • Luo, S.X.1    Deng, W.Y.2    Wang, X.F.3    Lu, H.F.4    Han, L.L.5    Chen, B.B.6
  • 83
    • 84860539736 scopus 로고    scopus 로고
    • Hepatoprotective effect of matrine salvianolic acid B salt on carbon tetrachloride-induced hepatic fibrosis
    • Gao HY, Li GY, Lou MM, Li XY, Wei XY, Wang JH. Hepatoprotective effect of matrine salvianolic acid B salt on carbon tetrachloride-induced hepatic fibrosis. J Inflamm (Lond). 2012;9:16.
    • (2012) J Inflamm (Lond) , vol.9 , pp. 16
    • Gao, H.Y.1    Li, G.Y.2    Lou, M.M.3    Li, X.Y.4    Wei, X.Y.5    Wang, J.H.6
  • 84
  • 85
    • 80054998123 scopus 로고    scopus 로고
    • Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonicalWnt/beta-catenin pathway
    • Xu W, Lin H, Zhang Y, Chen X, Hua B, Hou W, et al. Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonicalWnt/beta-catenin pathway. J Exp Clin Cancer Res. 2011;30:103.
    • (2011) J Exp Clin Cancer Res , vol.30 , pp. 103
    • Xu, W.1    Lin, H.2    Zhang, Y.3    Chen, X.4    Hua, B.5    Hou, W.6
  • 86
    • 84904755328 scopus 로고    scopus 로고
    • The recent effect of radiotherapy combined with compound kushen injection for esophageal cancer
    • Shao Q. The recent effect of radiotherapy combined with compound kushen injection for esophageal cancer. Radiother Oncol. 2011;99: S372-3.
    • (2011) Radiother Oncol , vol.99
    • Shao, Q.1
  • 87
    • 33746814577 scopus 로고    scopus 로고
    • Clinical study on effect of matrine injection to protect the liver function for patients with primary hepatic carcinoma after trans-artery chemo-embolization (TAE)
    • Lao Y. Clinical study on effect of matrine injection to protect the liver function for patients with primary hepatic carcinoma after trans-artery chemo-embolization (TAE). Zhong Yao Cai. 2005;28:637-8.
    • (2005) Zhong Yao Cai , vol.28 , pp. 637-638
    • Lao, Y.1
  • 89
    • 77649188639 scopus 로고    scopus 로고
    • Process optimization, characterization and evaluation in vivo of oxymatrine-phospholipid complex
    • Yue PF, Yuan HL, Li XY, Yang M, Zhu WF. Process optimization, characterization and evaluation in vivo of oxymatrine-phospholipid complex. Int J Pharm. 2010;387:139-46.
    • (2010) Int J Pharm , vol.387 , pp. 139-146
    • Yue, P.F.1    Yuan, H.L.2    Li, X.Y.3    Yang, M.4    Zhu, W.F.5
  • 90
    • 74149090979 scopus 로고    scopus 로고
    • Preparation and evaluation of self-nanoemulsified drug delivery systems (SNEDDSs) of matrine based on drug-phospholipid complex technique
    • Ruan J, Liu J, Zhu D, Gong T, Yang F, Hao X, et al. Preparation and evaluation of self-nanoemulsified drug delivery systems (SNEDDSs) of matrine based on drug-phospholipid complex technique. Int J Pharm. 2010;386:282-90.
    • (2010) Int J Pharm , vol.386 , pp. 282-290
    • Ruan, J.1    Liu, J.2    Zhu, D.3    Gong, T.4    Yang, F.5    Hao, X.6
  • 91
    • 84885090630 scopus 로고    scopus 로고
    • Determination of oxymatrine and its active metabolite matrine in human plasma after administration of oxymatrine oral solution by highperformance liquid chromatography coupled with mass spectrometry
    • Fan R, Liu R, Ma R, Bi K, Li Q. Determination of oxymatrine and its active metabolite matrine in human plasma after administration of oxymatrine oral solution by highperformance liquid chromatography coupled with mass spectrometry. Fitoterapia. 2013;89:271-7.
    • (2013) Fitoterapia , vol.89 , pp. 271-277
    • Fan, R.1    Liu, R.2    Ma, R.3    Bi, K.4    Li, Q.5
  • 92
    • 33646388386 scopus 로고    scopus 로고
    • Determination and pharmacokinetic study of oxymatrine and its metabolite matrine in human plasma by liquid chromatography tandem mass spectrometry
    • Wu XL, Hang TJ, Shen JP, Zhang YD. Determination and pharmacokinetic study of oxymatrine and its metabolite matrine in human plasma by liquid chromatography tandem mass spectrometry. J Pharml Biomed Anal. 2006;41(3):918-24.
    • (2006) J Pharml Biomed Anal , vol.41 , Issue.3 , pp. 918-924
    • Wu, X.L.1    Hang, T.J.2    Shen, J.P.3    Zhang, Y.D.4
  • 93
    • 74349130588 scopus 로고    scopus 로고
    • Clinically based evidence of drug-herb interactions: A systematic review
    • Kennedy DA, Seely D. Clinically based evidence of drug-herb interactions: a systematic review. Expert Opin Drug Saf. 2010;9(1):79-124.
    • (2010) Expert Opin Drug Saf , vol.9 , Issue.1 , pp. 79-124
    • Kennedy, D.A.1    Seely, D.2
  • 94
    • 21644475166 scopus 로고    scopus 로고
    • Synergistic effects of matrine and 5-fluorouracil on tumor growth of the implanted gastric cancer in nude mice
    • DOI 10.1111/j.1443-9573.2005.00201.x
    • Hu MJ, Zeng H, Wu YL, Zhang YP, Zhang S, Qiao MM, et al. Synergistic effects of matrine and 5-fluorouracil on tumor growth of the implanted gastric cancer in nudemice. Chin J Dig Dis. 2005;6(2):68-71. (Pubitemid 40936488)
    • (2005) Chinese Journal of Digestive Diseases , vol.6 , Issue.2 , pp. 68-71
    • Hu, M.J.1    Zeng, H.2    Wu, Y.L.3    Zhang, Y.P.4    Zhang, S.5    Qiao, M.M.6    Fu, H.7
  • 95
    • 84866278602 scopus 로고    scopus 로고
    • The influence of intraoperative pleural perfusion with matrinecisplatin or cisplatin on stromal cell-derived factor-1 in nonsmall cell lung cancer patients with subclinical pleural metastasis
    • Yang CL, Liu SS, Ma YG, Liu YY, Xue YX, Huang B. The influence of intraoperative pleural perfusion with matrinecisplatin or cisplatin on stromal cell-derived factor-1 in nonsmall cell lung cancer patients with subclinical pleural metastasis. Med Oncol. 2012;29(2):574-81.
    • (2012) Med Oncol , vol.29 , Issue.2 , pp. 574-581
    • Yang, C.L.1    Liu, S.S.2    Ma, Y.G.3    Liu, Y.Y.4    Xue, Y.X.5    Huang, B.6


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