-
1
-
-
79951497419
-
The genomic complexity of primary human prostate cancer
-
Berger MF, Lawrence MS, Demichelis F, Drier Y, Cibulskis K, Sivachenko AY, Sboner A, Esgueva R, Pflueger D, Sougnez C, Onofrio R, Carter SL, Park K, et al. The genomic complexity of primary human prostate cancer. Nature. 2011; 470: 214-20. doi: 10.1038/nature09744.
-
(2011)
Nature
, vol.470
, pp. 214-220
-
-
Berger, M.F.1
Lawrence, M.S.2
Demichelis, F.3
Drier, Y.4
Cibulskis, K.5
Sivachenko, A.Y.6
Sboner, A.7
Esgueva, R.8
Pflueger, D.9
Sougnez, C.10
Onofrio, R.11
Carter, S.L.12
Park, K.13
-
2
-
-
74449093973
-
A comprehensive catalogue of somatic mutations from a human cancer genome
-
Pleasance ED, Cheetham RK, Stephens PJ, McBride DJ, Humphray SJ, Greenman CD, Varela I, Lin ML, Ordonez GR, Bignell GR, Ye K, Alipaz J, Bauer MJ, et al. A comprehensive catalogue of somatic mutations from a human cancer genome. Nature. 2010; 463: 191-6. doi: 10.1038/nature08658.
-
(2010)
Nature
, vol.463
, pp. 191-196
-
-
Pleasance, E.D.1
Cheetham, R.K.2
Stephens, P.J.3
McBride, D.J.4
Humphray, S.J.5
Greenman, C.D.6
Varela, I.7
Lin, M.L.8
Ordonez, G.R.9
Bignell, G.R.10
Ye, K.11
Alipaz, J.12
Bauer, M.J.13
-
3
-
-
84943395444
-
Single-Cell Analysis in Cancer Genomics
-
Saadatpour A, Lai S, Guo G, Yuan GC. Single-Cell Analysis in Cancer Genomics. Trends Genet. 2015; 31: 576-86. doi: 10.1016/j.tig.2015.07.003.
-
(2015)
Trends Genet
, vol.31
, pp. 576-586
-
-
Saadatpour, A.1
Lai, S.2
Guo, G.3
Yuan, G.C.4
-
4
-
-
84931269218
-
Systematic transcriptome analysis reveals tumor-specific isoforms for ovarian cancer diagnosis and therapy
-
Barrett CL, DeBoever C, Jepsen K, Saenz CC, Carson DA, Frazer KA. Systematic transcriptome analysis reveals tumor-specific isoforms for ovarian cancer diagnosis and therapy. Proc Natl Acad Sci U S A. 2015; 112: E3050-7. doi: 10.1073/pnas.1508057112.
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. E3050-E3057
-
-
Barrett, C.L.1
DeBoever, C.2
Jepsen, K.3
Saenz, C.C.4
Carson, D.A.5
Frazer, K.A.6
-
5
-
-
84907915122
-
Transcriptome sequencing reveals altered long intergenic non-coding RNAs in lung cancer
-
White NM, Cabanski CR, Silva-Fisher JM, Dang HX, Govindan R, Maher CA. Transcriptome sequencing reveals altered long intergenic non-coding RNAs in lung cancer. Genome Biol. 2014; 15: 429. doi: 10.1186/s13059-014-0429-8.
-
(2014)
Genome Biol
, vol.15
, pp. 429
-
-
White, N.M.1
Cabanski, C.R.2
Silva-Fisher, J.M.3
Dang, H.X.4
Govindan, R.5
Maher, C.A.6
-
6
-
-
79961202865
-
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression
-
Prensner JR, Iyer MK, Balbin OA, Dhanasekaran SM, Cao Q, Brenner JC, Laxman B, Asangani IA, Grasso CS, Kominsky HD, Cao X, Jing X, Wang X, et al. Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression. Nat Biotechnol. 2011; 29: 742-9. doi: 10.1038/nbt.1914.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 742-749
-
-
Prensner, J.R.1
Iyer, M.K.2
Balbin, O.A.3
Dhanasekaran, S.M.4
Cao, Q.5
Brenner, J.C.6
Laxman, B.7
Asangani, I.A.8
Grasso, C.S.9
Kominsky, H.D.10
Cao, X.11
Jing, X.12
Wang, X.13
-
7
-
-
84877278637
-
Implementing personalized cancer genomics in clinical trials
-
Simon R, Roychowdhury S. Implementing personalized cancer genomics in clinical trials. Nat Rev Drug Discov. 2013; 12: 358-69. doi: 10.1038/nrd3979.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 358-369
-
-
Simon, R.1
Roychowdhury, S.2
-
8
-
-
77955058763
-
The role of traditional Chinese herbal medicines in cancer therapy from TCM theory to mechanistic insights
-
Hsiao WL, Liu L. The role of traditional Chinese herbal medicines in cancer therapy from TCM theory to mechanistic insights. Planta Med. 2010; 76: 1118-31. doi: 10.1055/s-0030-1250186.
-
(2010)
Planta Med
, vol.76
, pp. 1118-1131
-
-
Hsiao, W.L.1
Liu, L.2
-
9
-
-
84866149262
-
Antitumor activities of kushen: literature review
-
Sun M, Cao H, Sun L, Dong S, Bian Y, Han J, Zhang L, Ren S, Hu Y, Liu C, Xu L, Liu P. Antitumor activities of kushen: literature review. Evid Based Complement Alternat Med. 2012; 2012: 373219. doi: 10.1155/2012/373219.
-
(2012)
Evid Based Complement Alternat Med
, vol.2012
-
-
Sun, M.1
Cao, H.2
Sun, L.3
Dong, S.4
Bian, Y.5
Han, J.6
Zhang, L.7
Ren, S.8
Hu, Y.9
Liu, C.10
Xu, L.11
Liu, P.12
-
10
-
-
84908216805
-
Fufang Kushen injection inhibits sarcoma growth and tumorinduced hyperalgesia via TRPV1 signaling pathways
-
Zhao Z, Fan H, Higgins T, Qi J, Haines D, Trivett A, Oppenheim JJ, Wei H, Li J, Lin H, Howard OM. Fufang Kushen injection inhibits sarcoma growth and tumorinduced hyperalgesia via TRPV1 signaling pathways. Cancer Lett. 2014; 355: 232-41. doi: 10.1016/j. canlet.2014.08.037.
-
(2014)
Cancer Lett
, vol.355
, pp. 232-241
-
-
Zhao, Z.1
Fan, H.2
Higgins, T.3
Qi, J.4
Haines, D.5
Trivett, A.6
Oppenheim, J.J.7
Wei, H.8
Li, J.9
Lin, H.10
Howard, O.M.11
-
11
-
-
80054998123
-
Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/beta-catenin pathway
-
Xu W, Lin H, Zhang Y, Chen X, Hua B, Hou W, Qi X, Pei Y, Zhu X, Zhao Z, Yang L. Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/beta-catenin pathway. J Exp Clin Cancer Res. 2011; 30: 103. doi: 10.1186/1756-9966-30-103.
-
(2011)
J Exp Clin Cancer Res
, vol.30
, pp. 103
-
-
Xu, W.1
Lin, H.2
Zhang, Y.3
Chen, X.4
Hua, B.5
Hou, W.6
Qi, X.7
Pei, Y.8
Zhu, X.9
Zhao, Z.10
Yang, L.11
-
12
-
-
84887563876
-
Identification and Determination of the Chemical Constituents in a Herbal Preparation, Compound Kushen Injection, by Hplc and Lc-Dad-Ms/Ms
-
Ma Y, Gao HM, Liu J, Chen LM, Zhang QW, Wang ZM. Identification and Determination of the Chemical Constituents in a Herbal Preparation, Compound Kushen Injection, by Hplc and Lc-Dad-Ms/Ms. Journal of Liquid Chromatography & Related Technologies. 2014; 37: 207-20 doi: 10.1080/10826076.2012.738623.
-
(2014)
Journal of Liquid Chromatography & Related Technologies
, vol.37
, pp. 207-220
-
-
Ma, Y.1
Gao, H.M.2
Liu, J.3
Chen, L.M.4
Zhang, Q.W.5
Wang, Z.M.6
-
13
-
-
70449534614
-
Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-kappaB signaling
-
Yu P, Liu Q, Liu K, Yagasaki K, Wu E, Zhang G. Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-kappaB signaling. Cytotechnology. 2009; 59: 219-29. doi: 10.1007/s10616-009-9225-9.
-
(2009)
Cytotechnology
, vol.59
, pp. 219-229
-
-
Yu, P.1
Liu, Q.2
Liu, K.3
Yagasaki, K.4
Wu, E.5
Zhang, G.6
-
14
-
-
77957987817
-
Matrine inhibits proliferation and induces apoptosis of pancreatic cancer cells in vitro and in vivo
-
Liu T, Song Y, Chen H, Pan S, Sun X. Matrine inhibits proliferation and induces apoptosis of pancreatic cancer cells in vitro and in vivo. Biol Pharm Bull. 2010; 33: 1740-5. doi:
-
(2010)
Biol Pharm Bull
, vol.33
, pp. 1740-1745
-
-
Liu, T.1
Song, Y.2
Chen, H.3
Pan, S.4
Sun, X.5
-
15
-
-
84879665522
-
Antiangiogenic effects of oxymatrine on pancreatic cancer by inhibition of the NF-kappaB-mediated VEGF signaling pathway
-
Chen H, Zhang J, Luo J, Lai F, Wang Z, Tong H, Lu D, Bu H, Zhang R, Lin S. Antiangiogenic effects of oxymatrine on pancreatic cancer by inhibition of the NF-kappaB-mediated VEGF signaling pathway. Oncol Rep. 2013; 30: 589-95. doi: 10.3892/or.2013.2529.
-
(2013)
Oncol Rep
, vol.30
, pp. 589-595
-
-
Chen, H.1
Zhang, J.2
Luo, J.3
Lai, F.4
Wang, Z.5
Tong, H.6
Lu, D.7
Bu, H.8
Zhang, R.9
Lin, S.10
-
16
-
-
79959641621
-
Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome c
-
Ling Q, Xu X, Wei X, Wang W, Zhou B, Wang B, Zheng S. Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome c. J Exp Clin Cancer Res. 2011; 30: 66. doi: 10.1186/1756-9966-30-66.
-
(2011)
J Exp Clin Cancer Res
, vol.30
, pp. 66
-
-
Ling, Q.1
Xu, X.2
Wei, X.3
Wang, W.4
Zhou, B.5
Wang, B.6
Zheng, S.7
-
17
-
-
84655176705
-
Oxymatrine diminishes the side population and inhibits the expression of beta-catenin in MCF-7 breast cancer cells
-
Zhang Y, Piao B, Zhang Y, Hua B, Hou W, Xu W, Qi X, Zhu X, Pei Y, Lin H. Oxymatrine diminishes the side population and inhibits the expression of beta-catenin in MCF-7 breast cancer cells. Med Oncol. 2011; 28: S99-107. doi: 10.1007/s12032-010-9721-y.
-
(2011)
Med Oncol
, vol.28
, pp. S99-S107
-
-
Zhang, Y.1
Piao, B.2
Zhang, Y.3
Hua, B.4
Hou, W.5
Xu, W.6
Qi, X.7
Zhu, X.8
Pei, Y.9
Lin, H.10
-
18
-
-
84945548191
-
Efficacy of Compound Kushen Injection in Relieving Cancer-Related Pain: A Systematic Review and Meta-Analysis
-
Guo YM, Huang YX, Shen HH, Sang XX, Ma X, Zhao YL, Xiao XH. Efficacy of Compound Kushen Injection in Relieving Cancer-Related Pain: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2015; 2015: 840742. doi: 10.1155/2015/840742.
-
(2015)
Evid Based Complement Alternat Med
, vol.2015
-
-
Guo, Y.M.1
Huang, Y.X.2
Shen, H.H.3
Sang, X.X.4
Ma, X.5
Zhao, Y.L.6
Xiao, X.H.7
-
19
-
-
58049215467
-
A novel signaling pathway impact analysis
-
Tarca AL, Draghici S, Khatri P, Hassan SS, Mittal P, Kim JS, Kim CJ, Kusanovic JP, Romero R. A novel signaling pathway impact analysis. Bioinformatics. 2009; 25: 75-82. doi: 10.1093/bioinformatics/btn577.
-
(2009)
Bioinformatics
, vol.25
, pp. 75-82
-
-
Tarca, A.L.1
Draghici, S.2
Khatri, P.3
Hassan, S.S.4
Mittal, P.5
Kim, J.S.6
Kim, C.J.7
Kusanovic, J.P.8
Romero, R.9
-
20
-
-
84880803198
-
Control of cell cycle transcription during G1 and S phases
-
Bertoli C, Skotheim JM, de Bruin RA. Control of cell cycle transcription during G1 and S phases. Nat Rev Mol Cell Biol. 2013; 14: 518-28. doi: 10.1038/nrm3629.
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 518-528
-
-
Bertoli, C.1
Skotheim, J.M.2
de Bruin, R.A.3
-
22
-
-
84868276546
-
Overexpression of ETV4 is oncogenic in prostate cells through promotion of both cell proliferation and epithelial to mesenchymal transition
-
Pellecchia A, Pescucci C, De Lorenzo E, Luceri C, Passaro N, Sica M, Notaro R, De Angioletti M. Overexpression of ETV4 is oncogenic in prostate cells through promotion of both cell proliferation and epithelial to mesenchymal transition. Oncogenesis. 2012; 1: e20. doi: 10.1038/oncsis.2012.20.
-
(2012)
Oncogenesis
, vol.1
-
-
Pellecchia, A.1
Pescucci, C.2
De Lorenzo, E.3
Luceri, C.4
Passaro, N.5
Sica, M.6
Notaro, R.7
De Angioletti, M.8
-
23
-
-
80052978224
-
Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
-
Cabili MN, Trapnell C, GoffL, Koziol M, Tazon-Vega B, Regev A, Rinn JL. Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. Genes Dev. 2011; 25: 1915-27. doi: 10.1101/gad.17446611.
-
(2011)
Genes Dev
, vol.25
, pp. 1915-1927
-
-
Cabili, M.N.1
Trapnell, C.2
Goff, L.3
Koziol, M.4
Tazon-Vega, B.5
Regev, A.6
Rinn, J.L.7
-
24
-
-
84865727393
-
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression
-
Derrien T, Johnson R, Bussotti G, Tanzer A, Djebali S, Tilgner H, Guernec G, Martin D, Merkel A, Knowles DG, Lagarde J, Veeravalli L, Ruan X, et al. The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res. 2012; 22: 1775-89. doi: 10.1101/gr.132159.111.
-
(2012)
Genome Res
, vol.22
, pp. 1775-1789
-
-
Derrien, T.1
Johnson, R.2
Bussotti, G.3
Tanzer, A.4
Djebali, S.5
Tilgner, H.6
Guernec, G.7
Martin, D.8
Merkel, A.9
Knowles, D.G.10
Lagarde, J.11
Veeravalli, L.12
Ruan, X.13
-
25
-
-
84921731428
-
Identification of latent biomarkers in hepatocellular carcinoma by ultra-deep whole-transcriptome sequencing
-
Lin KT, Shann YJ, Chau GY, Hsu CN, Huang CY. Identification of latent biomarkers in hepatocellular carcinoma by ultra-deep whole-transcriptome sequencing. Oncogene. 2014; 33: 4786-94. doi: 10.1038/onc.2013.424.
-
(2014)
Oncogene
, vol.33
, pp. 4786-4794
-
-
Lin, K.T.1
Shann, Y.J.2
Chau, G.Y.3
Hsu, C.N.4
Huang, C.Y.5
-
26
-
-
84870495530
-
Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events
-
Liu J, Lee W, Jiang Z, Chen Z, Jhunjhunwala S, Haverty PM, Gnad F, Guan Y, Gilbert HN, Stinson J, Klijn C, Guillory J, Bhatt D, et al. Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events. Genome Res. 2012; 22: 2315-27. doi: 10.1101/gr.140988.112.
-
(2012)
Genome Res
, vol.22
, pp. 2315-2327
-
-
Liu, J.1
Lee, W.2
Jiang, Z.3
Chen, Z.4
Jhunjhunwala, S.5
Haverty, P.M.6
Gnad, F.7
Guan, Y.8
Gilbert, H.N.9
Stinson, J.10
Klijn, C.11
Guillory, J.12
Bhatt, D.13
-
27
-
-
84877134071
-
Human cytochrome P450 1A1 structure and utility in understanding drug and xenobiotic metabolism
-
Walsh AA, Szklarz GD, Scott EE. Human cytochrome P450 1A1 structure and utility in understanding drug and xenobiotic metabolism. J Biol Chem. 2013; 288: 12932-43. doi: 10.1074/jbc. M113.452953.
-
(2013)
J Biol Chem
, vol.288
, pp. 12932-12943
-
-
Walsh, A.A.1
Szklarz, G.D.2
Scott, E.E.3
-
28
-
-
33847021147
-
Aldo-keto reductases and bioactivation/detoxication
-
Jin Y, Penning TM. Aldo-keto reductases and bioactivation/detoxication. Annu Rev Pharmacol Toxicol. 2007; 47: 263-92 doi: 10.1146/annurev.pharmtox.47.120505.105337.
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 263-292
-
-
Jin, Y.1
Penning, T.M.2
-
29
-
-
0027154638
-
Cyclin D1 is a nuclear protein required for cell cycle progression in G1
-
Baldin V, Lukas J, Marcote MJ, Pagano M, Draetta G. Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes Dev. 1993; 7: 812-21. doi:
-
(1993)
Genes Dev
, vol.7
, pp. 812-821
-
-
Baldin, V.1
Lukas, J.2
Marcote, M.J.3
Pagano, M.4
Draetta, G.5
-
30
-
-
0030031360
-
Loss of H19 imprinting in esophageal cancer
-
Hibi K, Nakamura H, Hirai A, Fujikake Y, Kasai Y, Akiyama S, Ito K, Takagi H. Loss of H19 imprinting in esophageal cancer. Cancer Res. 1996; 56: 480-2. doi:
-
(1996)
Cancer Res
, vol.56
, pp. 480-482
-
-
Hibi, K.1
Nakamura, H.2
Hirai, A.3
Fujikake, Y.4
Kasai, Y.5
Akiyama, S.6
Ito, K.7
Takagi, H.8
-
31
-
-
18544405060
-
H19 overexpression in breast adenocarcinoma stromal cells is associated with tumor values and steroid receptor status but independent of p53 and Ki-67 expression
-
Adriaenssens E, Dumont L, Lottin S, Bolle D, Lepretre A, Delobelle A, Bouali F, Dugimont T, Coll J, Curgy JJ. H19 overexpression in breast adenocarcinoma stromal cells is associated with tumor values and steroid receptor status but independent of p53 and Ki-67 expression. Am J Pathol. 1998; 153: 1597-607. doi: 10.1016/S0002-9440(10)65748-3.
-
(1998)
Am J Pathol
, vol.153
, pp. 1597-1607
-
-
Adriaenssens, E.1
Dumont, L.2
Lottin, S.3
Bolle, D.4
Lepretre, A.5
Delobelle, A.6
Bouali, F.7
Dugimont, T.8
Coll, J.9
Curgy, J.J.10
-
32
-
-
84946196880
-
The emerging role of lncRNAs in cancer
-
Huarte M. The emerging role of lncRNAs in cancer. Nat Med. 2015; 21: 1253-61. doi: 10.1038/nm.3981.
-
(2015)
Nat Med
, vol.21
, pp. 1253-1261
-
-
Huarte, M.1
-
33
-
-
84875490185
-
Cancer genome landscapes
-
Vogelstein B, Papadopoulos N, Velculescu VE, Zhou S, Diaz LA, Jr., Kinzler KW. Cancer genome landscapes. Science. 2013; 339: 1546-58. doi: 10.1126/science.1235122.
-
(2013)
Science
, vol.339
, pp. 1546-1558
-
-
Vogelstein, B.1
Papadopoulos, N.2
Velculescu, V.E.3
Zhou, S.4
Diaz, L.A.5
Kinzler, K.W.6
-
34
-
-
84924407460
-
A comprehensive transcriptional portrait of human cancer cell lines
-
Klijn C, Durinck S, Stawiski EW, Haverty PM, Jiang Z, Liu H, Degenhardt J, Mayba O, Gnad F, Liu J, Pau G, Reeder J, Cao Y, et al. A comprehensive transcriptional portrait of human cancer cell lines. Nat Biotechnol. 2015; 33: 306-12. doi: 10.1038/nbt.3080.
-
(2015)
Nat Biotechnol
, vol.33
, pp. 306-312
-
-
Klijn, C.1
Durinck, S.2
Stawiski, E.W.3
Haverty, P.M.4
Jiang, Z.5
Liu, H.6
Degenhardt, J.7
Mayba, O.8
Gnad, F.9
Liu, J.10
Pau, G.11
Reeder, J.12
Cao, Y.13
-
35
-
-
84880861468
-
The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology
-
Abaan OD, Polley EC, Davis SR, Zhu YJ, Bilke S, Walker RL, Pineda M, Gindin Y, Jiang Y, Reinhold WC, Holbeck SL, Simon RM, Doroshow JH, et al. The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology. Cancer Res. 2013; 73: 4372-82. doi: 10.1158/0008-5472.CAN-12-3342.
-
(2013)
Cancer Res
, vol.73
, pp. 4372-4382
-
-
Abaan, O.D.1
Polley, E.C.2
Davis, S.R.3
Zhu, Y.J.4
Bilke, S.5
Walker, R.L.6
Pineda, M.7
Gindin, Y.8
Jiang, Y.9
Reinhold, W.C.10
Holbeck, S.L.11
Simon, R.M.12
Doroshow, J.H.13
-
36
-
-
0035110959
-
Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapy
-
Yoshikawa R, Kusunoki M, Yanagi H, Noda M, Furuyama JI, Yamamura T, Hashimoto-Tamaoki T. Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapy. Cancer Res. 2001; 61: 1029-37. doi:
-
(2001)
Cancer Res
, vol.61
, pp. 1029-1037
-
-
Yoshikawa, R.1
Kusunoki, M.2
Yanagi, H.3
Noda, M.4
Furuyama, J.I.5
Yamamura, T.6
Hashimoto-Tamaoki, T.7
-
37
-
-
33746437215
-
Transcriptional profiling of MCF7 breast cancer cells in response to 5-Fluorouracil: relationship with cell cycle changes and apoptosis, and identification of novel targets of p53
-
Hernandez-Vargas H, Ballestar E, Carmona-Saez P, von Kobbe C, Banon-Rodriguez I, Esteller M, Moreno-Bueno G, Palacios J. Transcriptional profiling of MCF7 breast cancer cells in response to 5-Fluorouracil: relationship with cell cycle changes and apoptosis, and identification of novel targets of p53. Int J Cancer. 2006; 119: 1164-75. doi: 10.1002/ijc.21938.
-
(2006)
Int J Cancer
, vol.119
, pp. 1164-1175
-
-
Hernandez-Vargas, H.1
Ballestar, E.2
Carmona-Saez, P.3
von Kobbe, C.4
Banon-Rodriguez, I.5
Esteller, M.6
Moreno-Bueno, G.7
Palacios, J.8
-
38
-
-
84890909335
-
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
-
Czabotar PE, Lessene G, Strasser A, Adams JM. Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy. Nat Rev Mol Cell Biol. 2014; 15: 49-63. doi: 10.1038/nrm3722.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 49-63
-
-
Czabotar, P.E.1
Lessene, G.2
Strasser, A.3
Adams, J.M.4
-
39
-
-
84880433393
-
Effects of matrine on the proliferation of HT29 human colon cancer cells and its antitumor mechanism
-
Chang C, Liu SP, Fang CH, He RS, Wang Z, Zhu YQ, Jiang SW. Effects of matrine on the proliferation of HT29 human colon cancer cells and its antitumor mechanism. Oncol Lett. 2013; 6: 699-704. doi: 10.3892/ol.2013.1449.
-
(2013)
Oncol Lett
, vol.6
, pp. 699-704
-
-
Chang, C.1
Liu, S.P.2
Fang, C.H.3
He, R.S.4
Wang, Z.5
Zhu, Y.Q.6
Jiang, S.W.7
-
40
-
-
70449533764
-
Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration
-
Zhang Y, Zhang H, Yu P, Liu Q, Liu K, Duan H, Luan G, Yagasaki K, Zhang G. Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration. Cytotechnology. 2009; 59: 191-200. doi: 10.1007/s10616-009-9211-2.
-
(2009)
Cytotechnology
, vol.59
, pp. 191-200
-
-
Zhang, Y.1
Zhang, H.2
Yu, P.3
Liu, Q.4
Liu, K.5
Duan, H.6
Luan, G.7
Yagasaki, K.8
Zhang, G.9
-
41
-
-
84904765047
-
Oxymatrine triggers apoptosis by regulating Bcl-2 family proteins and activating caspase-3/caspase-9 pathway in human leukemia HL-60 cells
-
Liu J, Yao Y, Ding H, Chen R. Oxymatrine triggers apoptosis by regulating Bcl-2 family proteins and activating caspase-3/caspase-9 pathway in human leukemia HL-60 cells. Tumour Biol. 2014; 35: 5409-15. doi: 10.1007/s13277-014-1705-7.
-
(2014)
Tumour Biol
, vol.35
, pp. 5409-5415
-
-
Liu, J.1
Yao, Y.2
Ding, H.3
Chen, R.4
-
42
-
-
84863651163
-
Combinatorial drug therapy for cancer in the post-genomic era
-
Al-Lazikani B, Banerji U, Workman P. Combinatorial drug therapy for cancer in the post-genomic era. Nat Biotechnol. 2012; 30: 679-92. doi: 10.1038/nbt.2284.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 679-692
-
-
Al-Lazikani, B.1
Banerji, U.2
Workman, P.3
-
43
-
-
84866149676
-
Genomic strategies for personalized cancer therapy
-
Garman KS, Nevins JR, Potti A. Genomic strategies for personalized cancer therapy. Hum Mol Genet. 2007; 16: R226-32. doi: 10.1093/hmg/ddm184.
-
(2007)
Hum Mol Genet
, vol.16
, pp. R226-R232
-
-
Garman, K.S.1
Nevins, J.R.2
Potti, A.3
-
44
-
-
84938350452
-
Combination cancer immunotherapy and new immunomodulatory targets
-
Mahoney KM, Rennert PD, Freeman GJ. Combination cancer immunotherapy and new immunomodulatory targets. Nat Rev Drug Discov. 2015; 14: 561-84. doi: 10.1038/nrd4591.
-
(2015)
Nat Rev Drug Discov
, vol.14
, pp. 561-584
-
-
Mahoney, K.M.1
Rennert, P.D.2
Freeman, G.J.3
-
45
-
-
41549108420
-
From single-to multi-target drugs in cancer therapy: when aspecificity becomes an advantage
-
Petrelli A, Giordano S. From single-to multi-target drugs in cancer therapy: when aspecificity becomes an advantage. Curr Med Chem. 2008; 15: 422-32. doi:
-
(2008)
Curr Med Chem
, vol.15
, pp. 422-432
-
-
Petrelli, A.1
Giordano, S.2
-
46
-
-
84858760109
-
Combining immunotherapy and targeted therapies in cancer treatment
-
Vanneman M, DranoffG. Combining immunotherapy and targeted therapies in cancer treatment. Nat Rev Cancer. 2012; 12: 237-51. doi: 10.1038/nrc3237.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 237-251
-
-
Vanneman, M.1
Dranoff, G.2
-
47
-
-
84872139132
-
Strategies and techniques for multi-component drug design from medicinal herbs and traditional Chinese medicine
-
Wang Y, Fan X, Qu H, Gao X, Cheng Y. Strategies and techniques for multi-component drug design from medicinal herbs and traditional Chinese medicine. Curr Top Med Chem. 2012; 12: 1356-62. doi:
-
(2012)
Curr Top Med Chem
, vol.12
, pp. 1356-1362
-
-
Wang, Y.1
Fan, X.2
Qu, H.3
Gao, X.4
Cheng, Y.5
-
48
-
-
84893867792
-
Gene co-expression network analysis reveals common system-level properties of prognostic genes across cancer types
-
Yang Y, Han L, Yuan Y, Li J, Hei N, Liang H. Gene co-expression network analysis reveals common system-level properties of prognostic genes across cancer types. Nat Commun. 2014; 5: 3231. doi: 10.1038/ncomms4231.
-
(2014)
Nat Commun
, vol.5
, pp. 3231
-
-
Yang, Y.1
Han, L.2
Yuan, Y.3
Li, J.4
Hei, N.5
Liang, H.6
-
49
-
-
34347215518
-
Analysis of apoptosis by propidium iodide staining and flow cytometry
-
Riccardi C, Nicoletti I. Analysis of apoptosis by propidium iodide staining and flow cytometry. Nat Protoc. 2006; 1: 1458-61. doi: 10.1038/nprot.2006.238.
-
(2006)
Nat Protoc
, vol.1
, pp. 1458-1461
-
-
Riccardi, C.1
Nicoletti, I.2
-
50
-
-
84871809302
-
STAR: ultrafast universal RNA-seq aligner
-
Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, Batut P, Chaisson M, Gingeras TR. STAR: ultrafast universal RNA-seq aligner. Bioinformatics. 2013; 29: 15-21. doi: 10.1093/bioinformatics/bts635.
-
(2013)
Bioinformatics
, vol.29
, pp. 15-21
-
-
Dobin, A.1
Davis, C.A.2
Schlesinger, F.3
Drenkow, J.4
Zaleski, C.5
Jha, S.6
Batut, P.7
Chaisson, M.8
Gingeras, T.R.9
-
51
-
-
75249087100
-
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
-
Robinson MD, McCarthy DJ, Smyth GK. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics. 2010; 26: 139-40. doi: 10.1093/bioinformatics/btp616.
-
(2010)
Bioinformatics
, vol.26
, pp. 139-140
-
-
Robinson, M.D.1
McCarthy, D.J.2
Smyth, G.K.3
-
52
-
-
64549104807
-
ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
-
Bindea G, Mlecnik B, Hackl H, Charoentong P, Tosolini M, Kirilovsky A, Fridman WH, Pages F, Trajanoski Z, Galon J. ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks. Bioinformatics. 2009; 25: 1091-3. doi: 10.1093/bioinformatics/btp101.
-
(2009)
Bioinformatics
, vol.25
, pp. 1091-1093
-
-
Bindea, G.1
Mlecnik, B.2
Hackl, H.3
Charoentong, P.4
Tosolini, M.5
Kirilovsky, A.6
Fridman, W.H.7
Pages, F.8
Trajanoski, Z.9
Galon, J.10
-
53
-
-
0242490780
-
Cytoscape: a software environment for integrated models of biomolecular interaction networks
-
Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, Amin N, Schwikowski B, Ideker T. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 2003; 13: 2498-504. doi: 10.1101/gr.1239303.
-
(2003)
Genome Res
, vol.13
, pp. 2498-2504
-
-
Shannon, P.1
Markiel, A.2
Ozier, O.3
Baliga, N.S.4
Wang, J.T.5
Ramage, D.6
Amin, N.7
Schwikowski, B.8
Ideker, T.9
-
54
-
-
84880199410
-
Pathview: an R/Bioconductor package for pathway-based data integration and visualization
-
Luo W, Brouwer C. Pathview: an R/Bioconductor package for pathway-based data integration and visualization. Bioinformatics. 2013; 29: 1830-1. doi: 10.1093/bioinformatics/btt285.
-
(2013)
Bioinformatics
, vol.29
, pp. 1830-1831
-
-
Luo, W.1
Brouwer, C.2
-
55
-
-
60549111634
-
WGCNA: an R package for weighted correlation network analysis
-
Langfelder P, Horvath S. WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics. 2008; 9: 559. doi: 10.1186/1471-2105-9-559.
-
(2008)
BMC Bioinformatics
, vol.9
, pp. 559
-
-
Langfelder, P.1
Horvath, S.2
-
56
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang da W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc. 2009; 4: 44-57. doi: 10.1038/nprot.2008.211.
-
(2009)
Nat Protoc
, vol.4
, pp. 44-57
-
-
Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
|