Endogenously generated omega-3 fatty acids attenuate vascular inflammation and neointimal hyperplasia by interaction with free fatty acid receptor 4 in mice

Journal of the American Heart Association

Volumn 4, Issue 4, 2015, Pages

  Li, Xinzhi ^a   Ballantyne, Laurel L ^a   Che, Xinghui ^a   Mewburn, Jeffrey D ^b   Kang, Jing X ^d   Barkley, Robert M ^e   Murphy, Robert C ^e   Yu, Ying ^c   Funk, Colin D ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

^c Chinese Academy of Sciences   (China)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Adipose tissue; Fatty acids; Inflammation; Omega 3 fatty acid receptor; Transgenic model

Indexed keywords

FERRIC CHLORIDE; G PROTEIN COUPLED RECEPTOR 120; OMEGA 3 FATTY ACID; G PROTEIN COUPLED RECEPTOR; O3FAR1 PROTEIN, MOUSE;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTERY BLOOD FLOW; ARTERY DIAMETER; ARTERY INTIMA; ARTERY INTIMA PROLIFERATION; ARTERY MEDIA; ARTERY THROMBOSIS; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; FATTY ACID SYNTHESIS; FEMALE; FEMORAL ARTERY; HEART PROTECTION; MACROPHAGE; MACROPHAGE MIGRATION; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LIPID INTERACTION; RECEPTOR UPREGULATION; THROMBOCYTE; VASCULAR DISEASE; VASCULITIS; ANIMAL; C57BL MOUSE; COMMON CAROTID ARTERY; FLUORESCENT ANTIBODY TECHNIQUE; HYPERPLASIA; INFLAMMATION; INTIMA; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CAROTID ARTERY, COMMON; FATTY ACIDS, OMEGA-3; FEMORAL ARTERY; FLUORESCENT ANTIBODY TECHNIQUE; HYPERPLASIA; INFLAMMATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUNICA INTIMA; VASCULITIS;

EID: 85012302464     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.115.001856     Document Type: Article

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