Mechanisms underlying FeCl3-induced arterial thrombosis

Journal of Thrombosis and Haemostasis

Volumn 9, Issue 4, 2011, Pages 779-789

  Eckly, A ^a   Hechler, B ^a   Freund, M ^a   Zerr, M ^a   Cazenave, J P ^a   Lanza, F ^a   Mangin, P H ^a   Gachet, C ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Carotid artery; Ferric chloride; Thrombosis; Tissue factor; Ultrastructure; Vascular injury

Indexed keywords

COLLAGEN; FERRIC CHLORIDE; FIBRINOGEN; GLYCOPROTEIN VI; VON WILLEBRAND FACTOR; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; CHLORIDE; FERRIC ION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY THROMBOSIS; ARTICLE; BASEMENT MEMBRANE; BLOOD CELL; BLOOD VESSEL INJURY; CAROTID ARTERY; CONTROLLED STUDY; ENDOTHELIUM CELL; IMMUNOGOLD LABELING; MESENTERIC ARTERY; MICROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE STRUCTURE; THROMBOGENESIS; ANIMAL; C57BL MOUSE; DISEASE MODEL; PATHOLOGY; SCANNING ELECTRON MICROSCOPY; THROMBOSIS; ULTRASTRUCTURE; VASCULAR DISEASE;

ANIMALS; ANTICOAGULANTS; CAROTID ARTERIES; CHLORIDES; DISEASE MODELS, ANIMAL; FERRIC COMPOUNDS; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, SCANNING; PLATELET AGGREGATION INHIBITORS; THROMBOSIS; VASCULAR DISEASES;

EID: 79953314017     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2011.04218.x     Document Type: Article

References (27)

1. Day SM, Reeve JL, Myers DD, Fay WP. Murine thrombosis models. Thromb Haemost 2004; 92: 486-94.
2. Denis CV, Wagner DD. Platelet adhesion receptors and their ligands in mouse models of thrombosis. Arterioscler Thromb Vasc Biol 2007; 27: 728-39.
3. Sachs UJ, Nieswandt B. In vivo thrombus formation in murine models. Circ Res 2007; 100: 979-91.
4. Westrick RJ, Winn ME, Eitzman DT. Murine models of vascular thrombosis (Eitzman series). Arterioscler Thromb Vasc Biol 2007; 27: 2079-93.
5. Tseng MT, Dozier A, Haribabu B, Graham UM. Transendothelial migration of ferric ion in FeCl3 injured murine common carotid artery. Thromb Res 2006; 118: 275-80.
6. Woollard KJ, Sturgeon S, Chin-Dusting JP, Salem HH, Jackson SP. Erythrocyte hemolysis and hemoglobin oxidation promote ferric chloride-induced vascular injury. J Biol Chem 2009; 284: 13110-8.
7. Dubois C, Panicot-Dubois L, Merrill-Skoloff G, Furie B, Furie BC. Glycoprotein VI-dependent and -independent pathways of thrombus formation in vivo. Blood 2006; 107: 3902-6.
8. Marsh Lyle E, Lewis SD, Lehman ED, Gardell SJ, Motzel SL, Lynch JJ Jr. Assessment of thrombin inhibitor efficacy in a novel rabbit model of simultaneous arterial and venous thrombosis. Thromb Haemost 1998; 79: 656-62.
9. Pinel C, Wice SM, Hiebert LM. Orally administered heparins prevent arterial thrombosis in a rat model. Thromb Haemost 2004; 91: 919-26.
10. Wang X, Cheng Q, Xu L, Feuerstein GZ, Hsu MY, Smith PL, Seiffert DA, Schumacher WA, Ogletree ML, Gailani D. Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice. J Thromb Haemost 2005; 3: 695-702.
11. Day SM, Reeve JL, Pedersen B, Farris DM, Myers DD, Im M, Wakefield TW, Mackman N, Fay WP. Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall. Blood 2005; 105: 192-8.
12. Gross PL, Furie BC, Merrill-Skoloff G, Chou J, Furie B. Leukocyte-versus microparticle-mediated tissue factor transfer during arteriolar thrombus development. J Leukoc Biol 2005; 78: 1318-26.
13. Polgar J, Matuskova J, Wagner DD. The P-selectin, tissue factor, coagulation triad. J Thromb Haemost 2005; 3: 1590-6.
14. Wang L, Miller C, Swarthout RF, Rao M, Mackman N, Taubman MB. Vascular smooth muscle-derived tissue factor is critical for arterial thrombosis after ferric chloride-induced injury. Blood 2009; 113: 705-13.
15. -/- mice. Blood 2008; 111: 1266-73.
16. Konstantinides S, Ware J, Marchese P, Almus-Jacobs F, Loskutoff DJ, Ruggeri ZM. Distinct antithrombotic consequences of platelet glycoprotein Ibalpha and VI deficiency in a mouse model of arterial thrombosis. J Thromb Haemost 2006; 4: 2014-21.
17. Kuijpers MJ, Pozgajova M, Cosemans JM, Munnix IC, Eckes B, Nieswandt B, Heemskerk JW. Role of murine integrin alpha2beta1 in thrombus stabilization and embolization: contribution of thromboxane A2. Thromb Haemost 2007; 98: 1072-80.
18. Massberg S, Gawaz M, Gruner S, Schulte V, Konrad I, Zohlnhofer D, Heinzmann U, Nieswandt B. A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo. J Exp Med 2003; 197: 41-9.
19. Nieswandt B, Schulte V, Bergmeier W, Mokhtari-Nejad R, Rackebrandt K, Cazenave JP, Ohlmann P, Gachet C, Zirngibl H. Long-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice. J Exp Med 2001; 193: 459-69.
20. Gachet C, Hanau D, Spehner D, Brisson C, Garaud JC, Schmitt DA, Ohlmann P, Cazenave JP. Alpha IIb beta 3 integrin dissociation induced by EDTA results in morphological changes of the platelet surface-connected canalicular system with differential location of the two separate subunits. J Cell Biol 1993; 120: 1021-30.
21. Cazenave JP, Hemmendinger S, Beretz A, Sutter-Bay A, Launay J. [Platelet aggregation: a tool for clinical investigation and pharmacological study. Methodology]. Ann Biol Clin (Paris) 1983; 41: 167-79.
22. Hechler B, Nonne C, Eckly A, Magnenat S, Rinckel JY, Denis CV, Freund M, Cazenave JP, Lanza F, Gachet C. Arterial thrombosis: relevance of a model with two levels of severity assessed by histologic, ultrastructural and functional characterization. J Thromb Haemost 2010; 8: 173-84.
23. Kurz KD, Main BW, Sandusky GE. Rat model of arterial thrombosis induced by ferric chloride. Thromb Res 1990; 60: 269-80.
24. Bergmeier W, Piffath CL, Goerge T, Cifuni SM, Ruggeri ZM, Ware J, Wagner DD. The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis. Proc Natl Acad Sci U S A 2006; 103: 16900-5.
25. Ni H, Denis CV, Subbarao S, Degen JL, Sato TN, Hynes RO, Wagner DD. Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. J Clin Invest 2000; 106: 385-92.
26. Rondaij MG, Bierings R, Kragt A, van Mourik JA, Voorberg J. Dynamics and plasticity of Weibel-Palade bodies in endothelial cells. Arterioscler Thromb Vasc Biol 2006; 26: 1002-7.
27. He L, Pappan LK, Grenache DG, Li Z, Tollefsen DM, Santoro SA, Zutter MM. The contributions of the alpha 2 beta 1 integrin to vascular thrombosis in vivo. Blood 2003; 102: 3652-7.