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Volumn 26, Issue 3, 2012, Pages 1100-1109

The cysteinyl leukotriene 2 receptor mediates retinal edema and pathological neovascularization in a murine model of oxygen-induced retinopathy

Author keywords

Inflammation; Pericyte

Indexed keywords

BETA GALACTOSIDASE; CYSTEINYL LEUKOTRIENE 2 RECEPTOR; LEUKOTRIENE; MESSENGER RNA; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 1;

EID: 84857743365     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-195792     Document Type: Article
Times cited : (21)

References (48)
  • 1
    • 0035808265 scopus 로고    scopus 로고
    • Intracellular compartmentalization of leukotriene synthesis: Unexpected nuclear secrets
    • DOI 10.1016/S0014-5793(00)02374-7, PII S0014579300023747
    • Peters-Golden, M., and Brock, T. G. (2001) Intracellular compartmentalization of leukotriene synthesis: unexpected nuclear secrets. FEBS Lett. 487, 323-326 (Pubitemid 32121750)
    • (2001) FEBS Letters , vol.487 , Issue.3 , pp. 323-326
    • Peters-Golden, M.1    Brock, T.G.2
  • 2
    • 0020597565 scopus 로고
    • Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammation
    • Samuelsson, B. (1983) Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science 220, 568-575
    • (1983) Science , vol.220 , pp. 568-575
    • Samuelsson, B.1
  • 6
    • 55949121449 scopus 로고    scopus 로고
    • Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors
    • Maekawa, A., Kanaoka, Y., Xing, W., and Austen, K. F. (2008) Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors. Proc. Natl. Acad. Sci. U. S. A. 105, 16695-16700
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 16695-16700
    • Maekawa, A.1    Kanaoka, Y.2    Xing, W.3    Austen, K.F.4
  • 7
    • 0000747598 scopus 로고
    • Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: In vivo effects with relevance to the acute inflammatory response
    • DOI 10.1073/pnas.78.6.3887
    • Dahlen, S. E., Bjork, J., Hedqvist, P., Arfors, K. E., Hammarstrom, S., Lindgren, J. A., and Samuelsson, B. (1981) Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response. Proc. Natl. Acad. Sci. U. S. A. 78, 3887-3891 (Pubitemid 11060581)
    • (1981) Proceedings of the National Academy of Sciences of the United States of America , vol.78 , Issue.6 I , pp. 3887-3891
    • Dahlen, S.E.1    Bjork, J.2    Hedqvist, P.3
  • 8
    • 57349129651 scopus 로고    scopus 로고
    • Cysteinyl leukotriene 2 receptor-mediated vascular permeability via transendothelial vesicle transport
    • Moos, M. P., Mewburn, J. D., Kan, F. W., Ishii, S., Abe, M., Sakimura, K., Noguchi, K., Shimizu, T., and Funk, C. D. (2008) Cysteinyl leukotriene 2 receptor-mediated vascular permeability via transendothelial vesicle transport. FASEB J. 22, 4352-4362
    • (2008) FASEB J. , vol.22 , pp. 4352-4362
    • Moos, M.P.1    Mewburn, J.D.2    Kan, F.W.3    Ishii, S.4    Abe, M.5    Sakimura, K.6    Noguchi, K.7    Shimizu, T.8    Funk, C.D.9
  • 9
    • 79959473804 scopus 로고    scopus 로고
    • Characterization of the cysteinyl leukotriene 2 receptor in novel expression sites of the gastrointestinal tract
    • Barajas-Espinosa, A., Ochoa-Cortes, F., Moos, M. P., Daniel Ramirez, F., Vanner, S. J., and Funk, C. D. (2011) Characterization of the cysteinyl leukotriene 2 receptor in novel expression sites of the gastrointestinal tract. Am. J. Pathol. 178, 2682-2689
    • (2011) Am. J. Pathol. , vol.178 , pp. 2682-2689
    • Barajas-Espinosa, A.1    Ochoa-Cortes, F.2    Moos, M.P.3    Daniel Ramirez, F.4    Vanner, S.J.5    Funk, C.D.6
  • 10
    • 0025870118 scopus 로고
    • Ischemia and reperfusion-induced histologic changes in the rat retina. Demonstration of a free radicalmediated mechanism
    • Szabo, M. E., Droy-Lefaix, M. T., Doly, M., Carre, C., and Braquet, P. (1991) Ischemia and reperfusion-induced histologic changes in the rat retina. Demonstration of a free radicalmediated mechanism. Invest. Ophthalmol. Vis. Sci. 32, 1471-1478
    • (1991) Invest. Ophthalmol. Vis. Sci. , vol.32 , pp. 1471-1478
    • Szabo, M.E.1    Droy-Lefaix, M.T.2    Doly, M.3    Carre, C.4    Braquet, P.5
  • 11
    • 0033506502 scopus 로고    scopus 로고
    • Mechanisms of fluid accumulation in retinal edema
    • Marmor, M. F. (1999) Mechanisms of fluid accumulation in retinal edema. Doc. Ophthalmol. 97, 239-249
    • (1999) Doc. Ophthalmol. , vol.97 , pp. 239-249
    • Marmor, M.F.1
  • 12
    • 55849146641 scopus 로고    scopus 로고
    • Blood-retinal barrier in hypoxic ischaemic conditions: Basic concepts, clinical features and management
    • Kaur, C., Foulds, W. S., and Ling, E. A. (2008) Blood-retinal barrier in hypoxic ischaemic conditions: basic concepts, clinical features and management. Prog. Retin. Eye Res. 27, 622-647
    • (2008) Prog. Retin. Eye Res. , vol.27 , pp. 622-647
    • Kaur, C.1    Foulds, W.S.2    Ling, E.A.3
  • 14
    • 0035746627 scopus 로고    scopus 로고
    • Pathogenesis of retinopathy of prematurity
    • Smith, L. E. (2002) Pathogenesis of retinopathy of prematurity. Acta Paediatr. Suppl. 91, 26-28
    • (2002) Acta Paediatr. Suppl. , vol.91 , pp. 26-28
    • Smith, L.E.1
  • 15
    • 48449097142 scopus 로고    scopus 로고
    • 5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy
    • Gubitosi-Klug, R. A., Talahalli, R., Du, Y., Nadler, J. L., and Kern, T. S. (2008) 5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy. Diabetes 57, 1387-1393
    • (2008) Diabetes , vol.57 , pp. 1387-1393
    • Gubitosi-Klug, R.A.1    Talahalli, R.2    Du, Y.3    Nadler, J.L.4    Kern, T.S.5
  • 18
    • 9344227345 scopus 로고    scopus 로고
    • Directed vascular expression of human cysteinyl leukotriene 2 receptor modulates endothelial permeability and systemic blood pressure
    • DOI 10.1161/01.CIR.0000147775.50954.AA
    • Hui, Y., Cheng, Y., Smalera, I., Jian, W., Goldhahn, L., Fitzgerald, G. A., and Funk, C. D. (2004) Directed vascular expression of human cysteinyl leukotriene 2 receptor modulates endothelial permeability and systemic blood pressure. Circulation 110, 3360-3366 (Pubitemid 39557500)
    • (2004) Circulation , vol.110 , Issue.21 , pp. 3360-3366
    • Hui, Y.1    Cheng, Y.2    Smalera, I.3    Jian, W.4    Goldhahn, L.5    FitzGerald, G.A.6    Funk, C.D.7
  • 23
    • 68949116297 scopus 로고    scopus 로고
    • Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice
    • Poeckel, D., Zemski Berry, K. A., Murphy, R. C., and Funk, C. D. (2009) Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice. J. Biol. Chem. 284, 21077-21089
    • (2009) J. Biol. Chem. , vol.284 , pp. 21077-21089
    • Poeckel, D.1    Zemski Berry, K.A.2    Murphy, R.C.3    Funk, C.D.4
  • 25
    • 0019259087 scopus 로고
    • Immunofluorescent imaging of capillaries and pericytes in human skeletal muscle and retina
    • DOI 10.1016/0026-2862(80)90010-2
    • Williamson, J. R., Tilton, R. G., Kilo, C., and Yu, S. (1980) Immunofluorescent imaging of capillaries and pericytes in human skeletal muscle and retina. Microvasc. Res. 20, 233-241 (Pubitemid 11146433)
    • (1980) Microvascular Research , vol.20 , Issue.2 , pp. 233-241
    • Williamson, J.R.1    Tilton, R.G.2    Kilo, C.3    Yu, S.4
  • 26
    • 0030270961 scopus 로고    scopus 로고
    • Pericytes in the microvasculature
    • DOI 10.1016/0008-6363(96)00063-6
    • Hirschi, K. K., and D'Amore, P. A. (1996) Pericytes in the microvasculature. Cardiovasc. Res. 32, 687-698 (Pubitemid 26332308)
    • (1996) Cardiovascular Research , vol.32 , Issue.4 , pp. 687-698
    • Hirschi, K.K.1    D'Amore, P.A.2
  • 28
    • 0013886259 scopus 로고
    • Pericytes in diabetic retinopathy
    • De Oliveira, F. (1966) Pericytes in diabetic retinopathy. Br. J. Ophthalmol. 50, 134-143
    • (1966) Br. J. Ophthalmol. , vol.50 , pp. 134-143
    • De Oliveira, F.1
  • 29
    • 4644292465 scopus 로고    scopus 로고
    • Desmin ensheathment ratio as an indicator of vessel stability: Evidence in normal development and in retinopathy of prematurity
    • Chan-Ling, T., Page, M. P., Gardiner, T., Baxter, L., Rosinova, E., and Hughes, S. (2004) Desmin ensheathment ratio as an indicator of vessel stability: evidence in normal development and in retinopathy of prematurity. Am. J. Pathol. 165, 1301-1313 (Pubitemid 39297735)
    • (2004) American Journal of Pathology , vol.165 , Issue.4 , pp. 1301-1313
    • Chan-Ling, T.1    Page, M.P.2    Gardiner, T.3    Baxter, L.4    Rosinova, E.5    Hughes, S.6
  • 30
    • 0000473767 scopus 로고
    • Extreme prematurity and fibroblastic over-growth of persistent vascular sheath behind each crystalline lens. I. Preliminary report
    • Terry, T. L. (1942) Extreme prematurity and fibroblastic over-growth of persistent vascular sheath behind each crystalline lens. I. Preliminary report. Am. J. Ophthalmol. 25, 203-203
    • (1942) Am. J. Ophthalmol. , vol.25 , pp. 203-203
    • Terry, T.L.1
  • 31
    • 79953859312 scopus 로고    scopus 로고
    • Current update on retinopathy of prematurity: Screening and treatment
    • Chen, J., Stahl, A., Hellstrom, A., and Smith, L. E. (2011) Current update on retinopathy of prematurity: screening and treatment. Curr. Opin. Pediatr. 23, 173-178
    • (2011) Curr. Opin. Pediatr. , vol.23 , pp. 173-178
    • Chen, J.1    Stahl, A.2    Hellstrom, A.3    Smith, L.E.4
  • 32
    • 48249123435 scopus 로고
    • Direct observation of the effect of oxygen on developing vessels: Preliminary report
    • Ashton, N., and Cook, C. (1954) Direct observation of the effect of oxygen on developing vessels: preliminary report. Br. J. Ophthalmol. 38, 433-440
    • (1954) Br. J. Ophthalmol. , vol.38 , pp. 433-440
    • Ashton, N.1    Cook, C.2
  • 33
    • 0042121131 scopus 로고    scopus 로고
    • Role of arteries in oxygen induced vaso-obliteration
    • DOI 10.1016/S0014-4835(03)00153-2
    • Claxton, S., and Fruttiger, M. (2003) Role of arteries in oxygen induced vaso-obliteration. Exp. Eye Res. 77, 305-311 (Pubitemid 36952369)
    • (2003) Experimental Eye Research , vol.77 , Issue.3 , pp. 305-311
    • Claxton, S.1    Fruttiger, M.2
  • 34
    • 33947308503 scopus 로고    scopus 로고
    • Retinopathy of prematurity
    • DOI 10.1007/s10456-007-9066-0
    • Chen, J., and Smith, L. E. (2007) Retinopathy of prematurity. Angiogenesis 10, 133-140 (Pubitemid 46440629)
    • (2007) Angiogenesis , vol.10 , Issue.2 , pp. 133-140
    • Chen, J.1    Smith, L.E.H.2
  • 36
    • 65449181610 scopus 로고    scopus 로고
    • Leukotriene D4 stimulates the migration but not proliferation of endothelial cells mediated by the cysteinyl leukotriene cyslt(1) receptor via the extracellular signal-regulated kinase pathway
    • Yuan, Y. M., Fang, S. H., Qian, X. D., Liu, L. Y., Xu, L. H., Shi, W. Z., Zhang, L. H., Lu, Y. B., Zhang, W. P., and Wei, E. Q. (2009) Leukotriene D4 stimulates the migration but not proliferation of endothelial cells mediated by the cysteinyl leukotriene cyslt(1) receptor via the extracellular signal-regulated kinase pathway. J. Pharmacol. Sci. 109, 285-292
    • (2009) J. Pharmacol. Sci. , vol.109 , pp. 285-292
    • Yuan, Y.M.1    Fang, S.H.2    Qian, X.D.3    Liu, L.Y.4    Xu, L.H.5    Shi, W.Z.6    Zhang, L.H.7    Lu, Y.B.8    Zhang, W.P.9    Wei, E.Q.10
  • 37
    • 7944239539 scopus 로고    scopus 로고
    • Cysteinyl leukotriene receptor antagonist regulates vascular permeability by reducing vascular endothelial growth factor expression
    • DOI 10.1016/j.jaci.2004.07.039, PII S0091674904020846
    • Lee, K. S., Kim, S. R., Park, H. S., Jin, G. Y., and Lee, Y. C. (2004) Cysteinyl leukotriene receptor antagonist regulates vascular permeability by reducing vascular endothelial growth factor expression. J. Allergy Clin. Immunol. 114, 1093-1099 (Pubitemid 39469149)
    • (2004) Journal of Allergy and Clinical Immunology , vol.114 , Issue.5 , pp. 1093-1099
    • Lee, K.S.1    Kim, S.R.2    Park, H.S.3    Jin, G.Y.4    Lee, Y.C.5
  • 38
    • 85047693011 scopus 로고    scopus 로고
    • Selective stimulation of VEGFR-1 prevents oxygen-induced retinal vascular degeneration in retinopathy of prematurity
    • DOI 10.1172/JCI200317808
    • Shih, S. C., Ju, M., Liu, N., and Smith, L. E. (2003) Selective stimulation of VEGFR-1 prevents oxygen-induced retinal vascular degeneration in retinopathy of prematurity. J. Clin. Invest. 112, 50-57 (Pubitemid 38056375)
    • (2003) Journal of Clinical Investigation , vol.112 , Issue.1 , pp. 50-57
    • Shih, S.-C.1    Ju, M.2    Liu, N.3    Smith, L.E.H.4
  • 39
    • 78751625796 scopus 로고    scopus 로고
    • Hypoxia differentially regulates VEGFR1 and VEGFR2 levels and alters intracellular signaling and cell migration in endothelial cells
    • Ulyatt, C., Walker, J., and Ponnambalam, S. (2011) Hypoxia differentially regulates VEGFR1 and VEGFR2 levels and alters intracellular signaling and cell migration in endothelial cells. Biochem. Biophys. Res. Commun. 404, 774-779
    • (2011) Biochem. Biophys. Res. Commun. , vol.404 , pp. 774-779
    • Ulyatt, C.1    Walker, J.2    Ponnambalam, S.3
  • 40
    • 80054082807 scopus 로고    scopus 로고
    • A selective cysteinyl leukotriene receptor 2 antagonist blocks myocardial ischemia/reperfusion injury and vascular permeability in mice
    • Ni, N. C., Yan, D., Ballantyne, L. L., Barajas-Espinosa, A., St Amand, T., Pratt, D. A., and Funk, C. D. (2011) A selective cysteinyl leukotriene receptor 2 antagonist blocks myocardial ischemia/reperfusion injury and vascular permeability in mice. J. Pharmacol. Exp. Ther. 339, 768-778
    • (2011) J. Pharmacol. Exp. Ther. , vol.339 , pp. 768-778
    • Ni, N.C.1    Yan, D.2    Ballantyne, L.L.3    Barajas-Espinosa, A.4    St Amand, T.5    Pratt, D.A.6    Funk, C.D.7
  • 43
    • 0028182712 scopus 로고
    • 4 promote angiogenesis via a receptor-mediated interaction
    • DOI 10.1016/0014-2999(94)90068-X
    • Tsopanoglou, N. E., Pipili-Synetos, E., and Maragoudakis, M. E. (1994) Leukotrienes C4 and D4 promote angiogenesis via a receptor-mediated interaction. Eur. J. Pharmacol. 258, 151-154 (Pubitemid 24174998)
    • (1994) European Journal of Pharmacology , vol.258 , Issue.1-2 , pp. 151-154
    • Tsopanoglou, N.E.1    Pipilo-Synetos, E.2    Maragoudakis, M.E.3
  • 44
    • 0023520990 scopus 로고
    • Synthesis of leukotrienes in frog retina and retinal pigment epithelium
    • DOI 10.1002/jnr.490180412
    • Bazan, N. G., Bazan, H. E., Birkle, D. L., and Rossowska, M. (1987) Synthesis of leukotrienes in frog retina and retinal pigment epithelium. J. Neurosci. Res. 18, 591-596 (Pubitemid 18007559)
    • (1987) Journal of Neuroscience Research , vol.18 , Issue.4 , pp. 591-596
    • Bazan, N.G.1    Bazan, H.E.P.2    Birkle, D.L.3    Rossowska, M.4
  • 45
    • 0028842616 scopus 로고
    • Lipid mediators in the rat retina: Light exposure and trauma elicit leukotriene B4 release in vitro
    • Reinboth, J. J., Gautschi, K., Clausen, M., and Reme, C. E. (1995) Lipid mediators in the rat retina: light exposure and trauma elicit leukotriene B4 release in vitro. Curr. Eye Res. 14, 1001-1008
    • (1995) Curr. Eye Res. , vol.14 , pp. 1001-1008
    • Reinboth, J.J.1    Gautschi, K.2    Clausen, M.3    Reme, C.E.4
  • 46
    • 0024212248 scopus 로고
    • Leukotriene generation and metabolism in isolated human lung macrophages
    • Schonfeld, W., Schluter, B., Hilger, R., and Konig, W. (1988) Leukotriene generation and metabolism in isolated human lung macrophages. Immunology 65, 529-536 (Pubitemid 19031206)
    • (1988) Immunology , vol.65 , Issue.4 , pp. 529-536
    • Schonfeld, W.1    Schluter, B.2    Hilger, R.3    Konig, W.4
  • 48
    • 79551584574 scopus 로고    scopus 로고
    • Increased expression and activity of 12-lipoxygenase in oxygeninduced ischemic retinopathy and proliferative diabetic retinopathy: Implications in retinal neovascularization
    • Al-Shabrawey, M., Mussell, R., Kahook, K., Tawfik, A., Eladl, M., Sarthy, V., Nussbaum, J., El-Marakby, A., Park, S. Y., Gurel, Z., Sheibani, N., and Maddipati, K. R. (2011) Increased expression and activity of 12-lipoxygenase in oxygeninduced ischemic retinopathy and proliferative diabetic retinopathy: implications in retinal neovascularization. Diabetes 60, 614-624
    • (2011) Diabetes , vol.60 , pp. 614-624
    • Al-Shabrawey, M.1    Mussell, R.2    Kahook, K.3    Tawfik, A.4    Eladl, M.5    Sarthy, V.6    Nussbaum, J.7    El-Marakby, A.8    Park, S.Y.9    Gurel, Z.10    Sheibani, N.11    Maddipati, K.R.12


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