Resolvin D2 prevents secondary thrombosis and necrosis in a mouse burn wound model

Wound Repair and Regeneration

Volumn 21, Issue 1, 2013, Pages 35-43

  Bohr, Stefan ^a   Patel, Suraj J ^a   Sarin, Dhruv ^a   Irimia, Daniel ^a   Yarmush, Martin L ^a,b   Berthiaume, Francois ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FATTY ACID DERIVATIVE; INTERLEUKIN 1BETA; MYELOPEROXIDASE; RESOLVIN D2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BURN; CELL INFILTRATION; CELLULAR DISTRIBUTION; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVITY; HISTOLOGY; INFLAMMATION; MALE; MICROVASCULATURE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE DRUG DOSE; SKIN NECROSIS; THROMBOSIS; WOUND CONTRACTION;

ANIMALS; BURNS; DISEASE MODELS, ANIMAL; DOCOSAHEXAENOIC ACIDS; FEMALE; INFLAMMATION; INTERLEUKIN-1BETA; MALE; MICE; MICE, INBRED C57BL; MICROVESSELS; NECROSIS; NEUTROPHILS; SKIN; THROMBOSIS; TUMOR NECROSIS FACTOR-ALPHA; WOUND HEALING;

EID: 84872104079     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/j.1524-475X.2012.00853.x     Document Type: Article

References (31)

1. Mecott GA, Al-Mousawi AM, Gauglitz GG, Herndon DN, Jeschke MG,. The role of hyperglycemia in burned patients: evidence-based studies. Shock 2010; 33: 5-13.
2. Kempf M, Cuttle L, Liu PY, Wang XQ, Kimble RM,. Important improvements to porcine skin burn models, in search of the perfect burn. Burns 2009; 35: 454-455.
3. Loos MS, Freeman BG, Lorenzetti A,. Zone of injury: a critical review of the literature. Ann Plast Surg 2010; 65: 573-577.
4. de Macedo JL, Santos JB,. Bacterial and fungal colonization of burn wounds. Mem Inst Oswaldo Cruz 2005; 100: 535-539.
5. Singer AJ, McClain SA, Taira BR, Rooney J, Steinhauff N, Rosenberg L,. Rapid and selective enzymatic debridement of porcine comb burns with bromelain-derived Debrase: acute-phase preservation of noninjured tissue and zone of stasis. J Burn Care Res 2010; 31: 304-309.
6. Nisanci M, Eski M, Sahin I, Ilgan S, Isik S,. Saving the zone of stasis in burns with activated protein C: an experimental study in rats. Burns 2010; 36: 397-402.
7. Parihar A, Parihar MS, Milner S, Bhat S,. Oxidative stress and anti-oxidative mobilization in burn injury. Burns 2008; 34: 6-17.
8. Wright K, Nwariaku F, Halaihel N, Schulman C, Yin HL, Turnage RH,. Burn-activated neutrophils and tumor necrosis factor-alpha alter endothelial cell actin cytoskeleton and enhance monolayer permeability. Surgery 2000; 128: 259-265.
9. Liu Q, Kishimoto TK, Mainolfi E, Deleon RP, Myers C, Moretz RC,. Dynamic expression of L-selectin in cell-to-cell interactions between neutrophils and endothelial cells in vitro. Exp Cell Res 1998; 243: 87-93.
10. Godin C, Caprani A, Dufaux J, Flaud P,. Interactions between neutrophils and endothelial cells. J Cell Sci 1993; 106 (Pt 2): 441-451.
11. Arita M, Yoshida M, Hong S, Tjonahen E, Glickman JN, Petasis NA, Blumberg RS, Serhan CN,. Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis. Proc Natl Acad Sci U S A 2005; 102: 7671-7676.
12. Serhan CN, Gotlinger K, Hong S, Arita M,. Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirin-triggered endogenous epimers: an overview of their protective roles in catabasis. Prostaglandins Other Lipid Mediat 2004; 73: 155-172.
13. Serhan CN, Hong S, Gronert K, Colgan SP, Devchand PR, Mirick G, Moussignac RL,. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J Exp Med 2002; 196: 1025-1037.
14. Spite M, Norling LV, Summers L, Yang R, Cooper D, Petasis NA, Flower RJ, Perretti M, Serhan CN,. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Nature 2009; 461: 1287-1291.
15. Krishnamoorthy S, Recchiuti A, Chiang N, Yacoubian S, Lee CH, Yang R, Petasis NA, Serhan CN,. Resolvin D1 binds human phagocytes with evidence for proresolving receptors. Proc Natl Acad Sci U S A 2010; 107: 1660-1665.
16. Schwab JM, Chiang N, Arita M, Serhan CN,. Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature 2007; 447: 869-874.
17. Duffield JS, Hong S, Vaidya VS, Lu Y, Fredman G, Serhan CN, Bonventre JV,. Resolvin D series and protectin D1 mitigate acute kidney injury. J Immunol 2006; 177: 5902-5911.
18. Filep JG,. Lipid mediator interplay: resolvin D1 attenuates inflammation evoked by glutathione-conjugated lipid peroxidation products. Br J Pharmacol 2009; 158: 1059-1061.
19. Regas FC, Ehrlich HP,. Elucidating the vascular response to burns with a new rat model. J Trauma 1992; 32: 557-563.
20. Singer AJBL, Thode HC Jr, McClain SA,. Standardized burn model using a multiparametric histologic analysis of burn depth. Acad Emerg Med 2000; 7: 1-6.
21. Chen CJ, Kono H, Golenbock D, Reed G, Akira S, Rock KL,. Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat Med 2007; 13: 851-856.
22. Galiano RD, Michaels J, Dobryansky M, Levine JP, Gurtner GC,. Quantitative and reproducible murine model of excisional wound healing. Wound Repair Regen 2004; 12: 485-492.
23. Boyle JJ,. Macrophage activation in atherosclerosis: pathogenesis and pharmacology of plaque rupture. Curr Vasc Pharmacol 2005; 3: 63-68.
24. Bernot D, Peiretti F, Canault M, Juhan-Vague I, Nalbone G,. Upregulation of TNF-alpha-induced ICAM-1 surface expression by adenylate cyclase-dependent pathway in human endothelial cells. J Cell Physiol 2005; 202: 434-441.
25. Wang T, Zhang X, Li JJ,. The role of NF-kappaB in the regulation of cell stress responses. Int Immunopharmacol 2002; 2: 1509-1520.
26. Shen F, Cheng GF,. Progresses in IkB kinase and related signal transduction. Sheng Li Ke Xue Jin Zhan 2001; 32: 80-82.
27. Schif-Zuck S, Gross N, Assi S, Rostoker R, Serhan CN, Ariel A,. Saturated-efferocytosis generates pro-resolving CD11b low macrophages: modulation by resolvins and glucocorticoids. Eur J Immunol 2011; 41: 366-379.
28. Fredman G, Oh SF, Ayilavarapu S, Hasturk H, Serhan CN, Van Dyke TE,. Impaired phagocytosis in localized aggressive periodontitis: rescue by Resolvin E1. PLoS ONE 2011; 6: e24422.
29. Martin P, Leibovich SJ,. Inflammatory cells during wound repair: the good, the bad and the ugly. Trends Cell Biol 2005; 15: 599-607.
30. Xu ZZ, Zhang L, Liu T, Park JY, Berta T, Yang R, Serhan CN, Ji RR,. Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions. Nat Med 2010; 16: 592-597. 591p following 597.
31. Park CK, Xu ZZ, Liu T, Lu N, Serhan CN, Ji RR,. Resolvin D2 is a potent endogenous inhibitor for transient receptor potential subtype V1/A1, inflammatory pain, and spinal cord synaptic plasticity in mice: distinct roles of resolvin D1, D2, and E1. J Neurosci 2011; 31: 18433-18438.