Elevated tissue omega-3 fatty acid status prevents age-related glucose intolerance in fat-1 transgenic mice

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1842, Issue 2, 2014, Pages 186-191

  Romanatto, Talita ^a,b   Fiamoncini, Jarlei ^b   Wang, Bin ^a   Curi, Rui ^b   Kang, Jing X ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Aging; Gluconeogenesis; Glucose homeostasis; Inflammation; Lipogenesis; Omega 3 fatty acid

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; CORN OIL; FATTY ACID SYNTHASE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; MEMBRANE PROTEIN; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PMP70 PROTEIN; PYRUVIC ACID; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

AGE RELATED GLUCOSE INTOLERANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIET SUPPLEMENTATION; EPIDIDYMIS FAT; FATTY ACID ANALYSIS; FUNCTION TEST; GENE EXPRESSION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; INSULIN BLOOD LEVEL; LIPID COMPOSITION; LIPID LIVER LEVEL; LIPOGENESIS; MALE; MOUSE; NONHUMAN; PEROXISOME; POTENTIAL DIFFERENCE; PRIORITY JOURNAL; PYRUVATE TOLERANCE TESTING; TRANSGENIC MOUSE; TRIACYLGLYCEROL BLOOD LEVEL; WILD TYPE;

70-KDA PEROXISOMAL MEMBRANE PROTEIN; ACC; ACETYL-COA CARBOXYLASE; ACOX1; ACYL-COA OXIDASE1; AGING; C-JUN KINASE; FAS; FATTY ACID SYNTHASE; G6PASE; GAS CHROMATOGRAPHY; GC; GLUCONEOGENESIS; GLUCOSE 6 PHOSPHATASE; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE TEST; GTT; IKK; INFLAMMATION; IΚB KINASE; JNK; LIPOGENESIS; MCP-1; MONOCYTE CHEMOATTRACTANT PROTEIN; N-3; N-6; NF-ΚB; NUCLEAR FACTOR-ΚB; OMEGA-3; OMEGA-3 FATTY ACID; OMEGA-6; PAI-1; PEPCK; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-Α; PHOSPHOENOLPYRUVATE CARBOXYKINASE; PLASMINOGEN ACTIVATOR INHIBITOR-1; PMP-70; POLYUNSATURATED FATTY ACIDS; PPARΑ; PTT; PUFA; PYRUVATE TOLERANCE TEST; TG; TNF-Α; TRIGLYCERIDE; TUMOR NECROSIS FACTOR Α; WILD-TYPE; WT;

ACETYL-COA CARBOXYLASE; AGE FACTORS; ANIMALS; BLOOD GLUCOSE; CAENORHABDITIS ELEGANS PROTEINS; FATTY ACID DESATURASES; FATTY ACID SYNTHASES; FATTY ACIDS, OMEGA-3; GENE EXPRESSION; GLUCONEOGENESIS; GLUCOSE; GLUCOSE INTOLERANCE; GLUCOSE-6-PHOSPHATASE; HOMEOSTASIS; IMMUNOBLOTTING; INSULIN; LIPOGENESIS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84890142204     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2013.10.017     Document Type: Article

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