STAT2 is an essential adaptor in USP18-mediated suppression of type i interferon signaling

Nature Structural and Molecular Biology

Volumn 24, Issue 3, 2017, Pages 279-289

  Arimoto, Kei Ichiro ^a   Löchte, Sara ^b   Stoner, Samuel A ^a   Burkart, Christoph ^a   Zhang, Yue ^c   Miyauchi, Sayuri ^a   Wilmes, Stephan ^b   Fan, Jun Bao ^a   Heinisch, Jürgen J ^b   Li, Zhi ^d   Yan, Ming ^a   Pellegrini, Sandra ^d   Colland, Frédéric ^e,g   Piehler, Jacob ^b   Zhang, Dong Er ^a,c,f  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF OSNABRÜCK   (Germany)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d INSTITUT PASTEUR   (France)

^e Hybrigenics SA   (France)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CELL SURFACE RECEPTOR; ENZYME; IFNAR2 PROTEIN; INTERFERON; INTERFERON RECEPTOR; JANUS KINASE 1; PROTEIN; SHORT HAIRPIN RNA; STAT1 PROTEIN; STAT2 PROTEIN; TYPE I INTERFERON; TYPE I INTERFERON RECEPTOR; UNCLASSIFIED DRUG; USP18 ENZYME; ALPHA BETA INTERFERON RECEPTOR; IFNAR2 PROTEIN, HUMAN; MUTANT PROTEIN; PROTEIN BINDING; PROTEINASE; USP18 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BINDING SITE; BONE MARROW CULTURE; CELL LYSATE; CONTROLLED STUDY; DIMERIZATION; DNA BINDING; EMBRYO; ENZYME PHOSPHORYLATION; FIBROBLAST; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENE EXPRESSION; HELA CELL LINE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN IMMOBILIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RECEPTOR BINDING ASSAY; SIGNAL TRANSDUCTION; TRANSACTIVATION; ANIMAL; CHEMISTRY; IMMUNOBLOTTING; METABOLISM; PHYSIOLOGICAL FEEDBACK; PROTEIN DOMAIN; TUMOR CELL LINE; TWO HYBRID SYSTEM;

ANIMALS; CELL LINE, TUMOR; ENDOPEPTIDASES; FEEDBACK, PHYSIOLOGICAL; HUMANS; IMMUNOBLOTTING; INTERFERON TYPE I; MICE; MUTANT PROTEINS; PROTEIN BINDING; PROTEIN DOMAINS; RECEPTOR, INTERFERON ALPHA-BETA; SIGNAL TRANSDUCTION; STAT2 TRANSCRIPTION FACTOR; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 85011691053     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.3378     Document Type: Article

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