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Volumn 275, Issue 51, 2000, Pages 40425-40433

New structural and functional aspects of the type I interferon-receptor interaction revealed by comprehensive mutational analysis of the binding interface

(3) Piehler, J a Roisman, L C a Schreiber, G a

a WEIZMANN INSTITUTE OF SCIENCE (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ALPHA2 INTERFERON; ARGININE; BINDING PROTEIN; CELL SURFACE RECEPTOR; INTERFERON; INTERFERON RECEPTOR; LEUCINE; METHIONINE; PROTEIN IFNAR2; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; BAY REGION BINDING SITE; DOSE TIME EFFECT RELATION; HYDROPHOBICITY; MITOSIS INHIBITION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR AFFINITY; RECEPTOR INTRINSIC ACTIVITY; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANTIVIRAL AGENTS; BINDING SITES; CELL DIVISION; CELL LINE; HUMANS; INTERFERON-ALPHA; KINETICS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RECEPTOR, INTERFERON ALPHA-BETA; RECEPTORS, INTERFERON; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 0034704093 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M006854200 Document Type: Article

Times cited : (138)

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