메뉴 건너뛰기




Volumn 9, Issue 10, 2013, Pages

Usp18 Driven Enforced Viral Replication in Dendritic Cells Contributes to Break of Immunological Tolerance in Autoimmune Diabetes

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA1 INTERFERON; AUTOANTIGEN; CROSS REACTING ANTIGEN; DIPHTHERIA TOXIN; RIBAVIRIN; UNCLASSIFIED DRUG; USP 18 PROTEIN; VIRUS PROTEIN;

EID: 84887305559     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003650     Document Type: Article
Times cited : (50)

References (50)
  • 2
    • 0036034940 scopus 로고    scopus 로고
    • The role of viruses in human diabetes
    • Hyoty H, Taylor KW, (2002) The role of viruses in human diabetes. Diabetologia 45: 1353-1361.
    • (2002) Diabetologia , vol.45 , pp. 1353-1361
    • Hyoty, H.1    Taylor, K.W.2
  • 3
    • 0036274774 scopus 로고    scopus 로고
    • Molecular mimicry in type 1 diabetes: immune cross-reactivity between islet autoantigen and human cytomegalovirus but not Coxsackie virus
    • Roep BO, Hiemstra HS, Schloot NC, De Vries RR, Chaudhuri A, et al. (2002) Molecular mimicry in type 1 diabetes: immune cross-reactivity between islet autoantigen and human cytomegalovirus but not Coxsackie virus. Annals of the New York Academy of Sciences 958: 163-165.
    • (2002) Annals of the New York Academy of Sciences , vol.958 , pp. 163-165
    • Roep, B.O.1    Hiemstra, H.S.2    Schloot, N.C.3    De Vries, R.R.4    Chaudhuri, A.5
  • 4
    • 0035044922 scopus 로고    scopus 로고
    • Molecular mimicry in type 1 diabetes mellitus revisited: T-cell clones to GAD65 peptides with sequence homology to Coxsackie or proinsulin peptides do not crossreact with homologous counterpart
    • Schloot NC, Willemen SJ, Duinkerken G, Drijfhout JW, de Vries RR, et al. (2001) Molecular mimicry in type 1 diabetes mellitus revisited: T-cell clones to GAD65 peptides with sequence homology to Coxsackie or proinsulin peptides do not crossreact with homologous counterpart. Human immunology 62: 299-309.
    • (2001) Human Immunology , vol.62 , pp. 299-309
    • Schloot, N.C.1    Willemen, S.J.2    Duinkerken, G.3    Drijfhout, J.W.4    de Vries, R.R.5
  • 7
    • 78650070483 scopus 로고    scopus 로고
    • Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY)
    • Stene LC, Oikarinen S, Hyoty H, Barriga KJ, Norris JM, et al. (2010) Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY). Diabetes 59: 3174-3180.
    • (2010) Diabetes , vol.59 , pp. 3174-3180
    • Stene, L.C.1    Oikarinen, S.2    Hyoty, H.3    Barriga, K.J.4    Norris, J.M.5
  • 8
    • 79952755799 scopus 로고    scopus 로고
    • Genome-virome interactions: examining the role of common viral infections in complex disease
    • Foxman EF, Iwasaki A, (2011) Genome-virome interactions: examining the role of common viral infections in complex disease. Nature reviews Microbiology 9: 254-264.
    • (2011) Nature Reviews Microbiology , vol.9 , pp. 254-264
    • Foxman, E.F.1    Iwasaki, A.2
  • 9
    • 33745240931 scopus 로고    scopus 로고
    • A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region
    • Smyth DJ, Cooper JD, Bailey R, Field S, Burren O, et al. (2006) A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nature genetics 38: 617-619.
    • (2006) Nature Genetics , vol.38 , pp. 617-619
    • Smyth, D.J.1    Cooper, J.D.2    Bailey, R.3    Field, S.4    Burren, O.5
  • 10
    • 66449085624 scopus 로고    scopus 로고
    • Diabetes: A virus-gene collaboration
    • von Herrath M, (2009) Diabetes: A virus-gene collaboration. Nature 459: 518-519.
    • (2009) Nature , vol.459 , pp. 518-519
    • von Herrath, M.1
  • 11
    • 0027201783 scopus 로고
    • Islet cell autoantigen 69 kD (ICA69). Molecular cloning and characterization of a novel diabetes-associated autoantigen
    • Pietropaolo M, Castano L, Babu S, Buelow R, Kuo YL, et al. (1993) Islet cell autoantigen 69 kD (ICA69). Molecular cloning and characterization of a novel diabetes-associated autoantigen. The Journal of clinical investigation 92: 359-371.
    • (1993) The Journal of Clinical Investigation , vol.92 , pp. 359-371
    • Pietropaolo, M.1    Castano, L.2    Babu, S.3    Buelow, R.4    Kuo, Y.L.5
  • 13
    • 0030571188 scopus 로고    scopus 로고
    • Cell-mediated immune response to beta casein in recent-onset insulin-dependent diabetes: implications for disease pathogenesis
    • Cavallo MG, Fava D, Monetini L, Barone F, Pozzilli P, (1996) Cell-mediated immune response to beta casein in recent-onset insulin-dependent diabetes: implications for disease pathogenesis. Lancet 348: 926-928.
    • (1996) Lancet , vol.348 , pp. 926-928
    • Cavallo, M.G.1    Fava, D.2    Monetini, L.3    Barone, F.4    Pozzilli, P.5
  • 15
    • 0030029167 scopus 로고    scopus 로고
    • Cellular immune response to cow's milk beta-lactoglobulin in patients with newly diagnosed IDDM
    • Vaarala O, Klemetti P, Savilahti E, Reijonen H, Ilonen J, et al. (1996) Cellular immune response to cow's milk beta-lactoglobulin in patients with newly diagnosed IDDM. Diabetes 45: 178-182.
    • (1996) Diabetes , vol.45 , pp. 178-182
    • Vaarala, O.1    Klemetti, P.2    Savilahti, E.3    Reijonen, H.4    Ilonen, J.5
  • 16
    • 4344698785 scopus 로고    scopus 로고
    • Peptides from common viral and bacterial pathogens can efficiently activate diabetogenic T-cells
    • Judkowski VA, Allicotti GM, Sarvetnick N, Pinilla C, (2004) Peptides from common viral and bacterial pathogens can efficiently activate diabetogenic T-cells. Diabetes 53: 2301-2309.
    • (2004) Diabetes , vol.53 , pp. 2301-2309
    • Judkowski, V.A.1    Allicotti, G.M.2    Sarvetnick, N.3    Pinilla, C.4
  • 17
    • 80055054851 scopus 로고    scopus 로고
    • Antibodies recognizing Mycobacterium avium paratuberculosis epitopes cross-react with the beta-cell antigen ZnT8 in Sardinian type 1 diabetic patients
    • Masala S, Paccagnini D, Cossu D, Brezar V, Pacifico A, et al. (2011) Antibodies recognizing Mycobacterium avium paratuberculosis epitopes cross-react with the beta-cell antigen ZnT8 in Sardinian type 1 diabetic patients. PloS one 6: e26931.
    • (2011) PloS One , vol.6
    • Masala, S.1    Paccagnini, D.2    Cossu, D.3    Brezar, V.4    Pacifico, A.5
  • 19
    • 78649510272 scopus 로고    scopus 로고
    • The stromal and haematopoietic antigen-presenting cells that reside in secondary lymphoid organs
    • Turley SJ, Fletcher AL, Elpek KG, (2010) The stromal and haematopoietic antigen-presenting cells that reside in secondary lymphoid organs. Nature reviews Immunology 10: 813-825.
    • (2010) Nature Reviews Immunology , vol.10 , pp. 813-825
    • Turley, S.J.1    Fletcher, A.L.2    Elpek, K.G.3
  • 20
    • 0034210006 scopus 로고    scopus 로고
    • Localization dose and time of antigens determine immune reactivity
    • Zinkernagel RM, (2000) Localization dose and time of antigens determine immune reactivity. Semin Immunol 12: 163-171.
    • (2000) Semin Immunol , vol.12 , pp. 163-171
    • Zinkernagel, R.M.1
  • 21
    • 0030975532 scopus 로고    scopus 로고
    • Antigen localisation regulates immune responses in a dose- and time-dependent fashion: a geographical view of immune reactivity
    • Zinkernagel RM, Ehl S, Aichele P, Oehen S, Kundig T, et al. (1997) Antigen localisation regulates immune responses in a dose- and time-dependent fashion: a geographical view of immune reactivity. Immunol Rev 156: 199-209.
    • (1997) Immunol Rev , vol.156 , pp. 199-209
    • Zinkernagel, R.M.1    Ehl, S.2    Aichele, P.3    Oehen, S.4    Kundig, T.5
  • 22
    • 0344407023 scopus 로고    scopus 로고
    • High antigen dose and activated dendritic cells enable Th cells to escape regulatory T cell-mediated suppression in vitro
    • George TC, Bilsborough J, Viney JL, Norment AM, (2003) High antigen dose and activated dendritic cells enable Th cells to escape regulatory T cell-mediated suppression in vitro. European journal of immunology 33: 502-511.
    • (2003) European Journal of Immunology , vol.33 , pp. 502-511
    • George, T.C.1    Bilsborough, J.2    Viney, J.L.3    Norment, A.M.4
  • 23
    • 34250162775 scopus 로고    scopus 로고
    • Low-dose peptide tolerance therapy of lupus generates plasmacytoid dendritic cells that cause expansion of autoantigen-specific regulatory T cells and contraction of inflammatory Th17 cells
    • Kang HK, Liu M, Datta SK, (2007) Low-dose peptide tolerance therapy of lupus generates plasmacytoid dendritic cells that cause expansion of autoantigen-specific regulatory T cells and contraction of inflammatory Th17 cells. Journal of immunology 178: 7849-7858.
    • (2007) Journal of Immunology , vol.178 , pp. 7849-7858
    • Kang, H.K.1    Liu, M.2    Datta, S.K.3
  • 24
    • 15844411342 scopus 로고    scopus 로고
    • Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation
    • Lang KS, Recher M, Navarini AA, Harris NL, Lohning M, et al. (2005) Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation. European journal of immunology 35: 738-745.
    • (2005) European Journal of Immunology , vol.35 , pp. 738-745
    • Lang, K.S.1    Recher, M.2    Navarini, A.A.3    Harris, N.L.4    Lohning, M.5
  • 26
    • 83755222543 scopus 로고    scopus 로고
    • Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus
    • Honke N, Shaabani N, Cadeddu G, Sorg UR, Zhang DE, et al. (2012) Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus. Nature immunology 13: 51-57.
    • (2012) Nature Immunology , vol.13 , pp. 51-57
    • Honke, N.1    Shaabani, N.2    Cadeddu, G.3    Sorg, U.R.4    Zhang, D.E.5
  • 27
    • 0025755292 scopus 로고
    • Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice
    • Ohashi PS, Oehen S, Buerki K, Pircher H, Ohashi CT, et al. (1991) Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell 65: 305-317.
    • (1991) Cell , vol.65 , pp. 305-317
    • Ohashi, P.S.1    Oehen, S.2    Buerki, K.3    Pircher, H.4    Ohashi, C.T.5
  • 28
    • 18644375874 scopus 로고    scopus 로고
    • In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens
    • Jung S, Unutmaz D, Wong P, Sano G-I, De los Santos K, et al. (2002) In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity 17: 211-220.
    • (2002) Immunity , vol.17 , pp. 211-220
    • Jung, S.1    Unutmaz, D.2    Wong, P.3    Sano, G.-I.4    De los Santos, K.5
  • 29
    • 35948930165 scopus 로고    scopus 로고
    • Extralymphatic virus sanctuaries as a consequence of potent T-cell activation
    • Recher M, Lang KS, Navarini A, Hunziker L, Lang PA, et al. (2007) Extralymphatic virus sanctuaries as a consequence of potent T-cell activation. Nature medicine 13: 1316-1323.
    • (2007) Nature Medicine , vol.13 , pp. 1316-1323
    • Recher, M.1    Lang, K.S.2    Navarini, A.3    Hunziker, L.4    Lang, P.A.5
  • 31
    • 0024550913 scopus 로고
    • Homologous interference of lymphocytic choriomeningitis virus involves a ribavirin-susceptible block in virus replication
    • Gessner A, Lother H, (1989) Homologous interference of lymphocytic choriomeningitis virus involves a ribavirin-susceptible block in virus replication. Journal of virology 63: 1827-1832.
    • (1989) Journal of Virology , vol.63 , pp. 1827-1832
    • Gessner, A.1    Lother, H.2
  • 32
    • 33745761009 scopus 로고    scopus 로고
    • UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity
    • Malakhova OA, Kim KI, Luo JK, Zou W, Kumar KG, et al. (2006) UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity. EMBO J 25: 2358-2367.
    • (2006) EMBO J , vol.25 , pp. 2358-2367
    • Malakhova, O.A.1    Kim, K.I.2    Luo, J.K.3    Zou, W.4    Kumar, K.G.5
  • 33
    • 11144294823 scopus 로고    scopus 로고
    • Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection
    • Ritchie KJ, Hahn CS, Kim KI, Yan M, Rosario D, et al. (2004) Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection. Nat Med 10: 1374-1378.
    • (2004) Nat Med , vol.10 , pp. 1374-1378
    • Ritchie, K.J.1    Hahn, C.S.2    Kim, K.I.3    Yan, M.4    Rosario, D.5
  • 34
    • 20044385554 scopus 로고    scopus 로고
    • Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease
    • Lang KS, Recher M, Junt T, Navarini AA, Harris NL, et al. (2005) Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. Nature medicine 11: 138-145.
    • (2005) Nature Medicine , vol.11 , pp. 138-145
    • Lang, K.S.1    Recher, M.2    Junt, T.3    Navarini, A.A.4    Harris, N.L.5
  • 35
    • 0024307348 scopus 로고
    • Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
    • Pircher H, Burki K, Lang R, Hengartner H, Zinkernagel RM, (1989) Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 342: 559-561.
    • (1989) Nature , vol.342 , pp. 559-561
    • Pircher, H.1    Burki, K.2    Lang, R.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 36
    • 37549029242 scopus 로고    scopus 로고
    • The mechanisms of alloxan- and streptozotocin-induced diabetes
    • Lenzen S, (2008) The mechanisms of alloxan- and streptozotocin-induced diabetes. Diabetologia 51: 216-226.
    • (2008) Diabetologia , vol.51 , pp. 216-226
    • Lenzen, S.1
  • 37
    • 0037384180 scopus 로고    scopus 로고
    • Hypergammaglobulinemia and autoantibody induction mechanisms in viral infections
    • Hunziker L, Recher M, Macpherson AJ, Ciurea A, Freigang S, et al. (2003) Hypergammaglobulinemia and autoantibody induction mechanisms in viral infections. Nature immunology 4: 343-349.
    • (2003) Nature Immunology , vol.4 , pp. 343-349
    • Hunziker, L.1    Recher, M.2    Macpherson, A.J.3    Ciurea, A.4    Freigang, S.5
  • 39
    • 0028446546 scopus 로고
    • How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model
    • von Herrath MG, Dockter J, Oldstone MB, (1994) How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model. Immunity 1: 231-242.
    • (1994) Immunity , vol.1 , pp. 231-242
    • von Herrath, M.G.1    Dockter, J.2    Oldstone, M.B.3
  • 40
    • 84872874592 scopus 로고    scopus 로고
    • Blockade but not overexpression of the junctional adhesion molecule C influences virus-induced type 1 diabetes in mice
    • Christen S, Coppieters K, Rose K, Holdener M, Bayer M, et al. (2013) Blockade but not overexpression of the junctional adhesion molecule C influences virus-induced type 1 diabetes in mice. PloS one 8: e54675.
    • (2013) PloS One , vol.8
    • Christen, S.1    Coppieters, K.2    Rose, K.3    Holdener, M.4    Bayer, M.5
  • 41
    • 11144231103 scopus 로고    scopus 로고
    • DC infection promotes antiviral CTL priming: the 'Winkelried' strategy
    • Freigang S, Probst HC, van den Broek M, (2005) DC infection promotes antiviral CTL priming: the 'Winkelried' strategy. Trends in immunology 26: 13-18.
    • (2005) Trends in Immunology , vol.26 , pp. 13-18
    • Freigang, S.1    Probst, H.C.2    van den Broek, M.3
  • 42
  • 43
    • 77955596988 scopus 로고    scopus 로고
    • Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress
    • Seifert U, Bialy LP, Ebstein F, Bech-Otschir D, Voigt A, et al. (2010) Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress. Cell 142: 613-624.
    • (2010) Cell , vol.142 , pp. 613-624
    • Seifert, U.1    Bialy, L.P.2    Ebstein, F.3    Bech-Otschir, D.4    Voigt, A.5
  • 44
    • 0142092614 scopus 로고    scopus 로고
    • Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon
    • Le Bon A, Etchart N, Rossmann C, Ashton M, Hou S, et al. (2003) Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon. Nat Immunol 4: 1009-1015.
    • (2003) Nat Immunol , vol.4 , pp. 1009-1015
    • Le Bon, A.1    Etchart, N.2    Rossmann, C.3    Ashton, M.4    Hou, S.5
  • 45
    • 67650445798 scopus 로고    scopus 로고
    • Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
    • Longhi MP, Trumpfheller C, Idoyaga J, Caskey M, Matos I, et al. (2009) Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant. J Exp Med 206: 1589-1602.
    • (2009) J Exp Med , vol.206 , pp. 1589-1602
    • Longhi, M.P.1    Trumpfheller, C.2    Idoyaga, J.3    Caskey, M.4    Matos, I.5
  • 46
    • 0347122087 scopus 로고    scopus 로고
    • Hsp70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo
    • Millar DG, Garza KM, Odermatt B, Elford AR, Ono N, et al. (2003) Hsp70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo. Nature medicine 9: 1469-1476.
    • (2003) Nature Medicine , vol.9 , pp. 1469-1476
    • Millar, D.G.1    Garza, K.M.2    Odermatt, B.3    Elford, A.R.4    Ono, N.5
  • 47
    • 65249131713 scopus 로고    scopus 로고
    • Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes
    • Nejentsev S, Walker N, Riches D, Egholm M, Todd JA, (2009) Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes. Science 324: 387-389.
    • (2009) Science , vol.324 , pp. 387-389
    • Nejentsev, S.1    Walker, N.2    Riches, D.3    Egholm, M.4    Todd, J.A.5
  • 48
    • 77957126059 scopus 로고    scopus 로고
    • A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk
    • Heinig M, Petretto E, Wallace C, Bottolo L, Rotival M, et al. (2010) A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature 467: 460-464.
    • (2010) Nature , vol.467 , pp. 460-464
    • Heinig, M.1    Petretto, E.2    Wallace, C.3    Bottolo, L.4    Rotival, M.5
  • 49
    • 84870508724 scopus 로고    scopus 로고
    • USP18 is a key regulator of the interferon-driven gene network modulating pancreatic beta cell inflammation and apoptosis
    • Santin I, Moore F, Grieco FA, Marchetti P, Brancolini C, et al. (2012) USP18 is a key regulator of the interferon-driven gene network modulating pancreatic beta cell inflammation and apoptosis. Cell death & disease 3: e419.
    • (2012) Cell Death & Disease , vol.3
    • Santin, I.1    Moore, F.2    Grieco, F.A.3    Marchetti, P.4    Brancolini, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.