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Volumn 4, Issue 3, 2016, Pages

Tumor-induced myeloid-derived suppressor cells

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; HUMAN; IMMUNOLOGY; MYELOID-DERIVED SUPPRESSOR CELL; NEOPLASM; PATHOLOGY; PHYSIOLOGY;

EID: 85011286219     PISSN: None     EISSN: 21650497     Source Type: Journal    
DOI: 10.1128/microbiolspec.MCHD-0016-2015     Document Type: Article
Times cited : (27)

References (202)
  • 1
    • 74949090309 scopus 로고    scopus 로고
    • The therapeutic promise of the cancer stem cell concept
    • Frank NY, Schatton T, Frank MH. 2010. The therapeutic promise of the cancer stem cell concept. J Clin Invest 120:41-50.
    • (2010) J Clin Invest , vol.120 , pp. 41-50
    • Frank, N.Y.1    Schatton, T.2    Frank, M.H.3
  • 2
    • 17644394616 scopus 로고    scopus 로고
    • Smoldering and polarized inflammation in the initiation and promotion of malignant disease
    • Balkwill F, Charles KA, Mantovani A. 2005. Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 7:211-217.
    • (2005) Cancer Cell , vol.7 , pp. 211-217
    • Balkwill, F.1    Charles, K.A.2    Mantovani, A.3
  • 3
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion
    • Schreiber RD, Old LJ, Smyth MJ. 2011. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science 331:1565-1570.
    • (2011) Science , vol.331 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 4
  • 6
    • 0030786569 scopus 로고    scopus 로고
    • Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression in rats
    • Chaux P, Favre N, Martin M, Martin F. 1997. Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression in rats. Int J Cancer 72:619-624.
    • (1997) Int J Cancer , vol.72 , pp. 619-624
    • Chaux, P.1    Favre, N.2    Martin, M.3    Martin, F.4
  • 8
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich DI, Nagaraj S. 2009. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 9:162-174.
    • (2009) Nat Rev Immunol , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 9
    • 0021558066 scopus 로고
    • Natural suppressor (NS) cells, neonatal tolerance, and total lymphoid irradiation: exploring obscure relationships
    • Strober S. 1984. Natural suppressor (NS) cells, neonatal tolerance, and total lymphoid irradiation: exploring obscure relationships. Annu Rev Immunol 2:219-237.
    • (1984) Annu Rev Immunol , vol.2 , pp. 219-237
    • Strober, S.1
  • 10
    • 0029078313 scopus 로고
    • Synergy between T-cell immunity and inhibition of paracrine stimulation causes tumor rejection
    • Seung LP, Rowley DA, Dubey P, Schreiber H. 1995. Synergy between T-cell immunity and inhibition of paracrine stimulation causes tumor rejection. Proc Natl Acad Sci U S A 92:6254-6258.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 6254-6258
    • Seung, L.P.1    Rowley, D.A.2    Dubey, P.3    Schreiber, H.4
  • 11
    • 31344474166 scopus 로고    scopus 로고
    • Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression
    • Serafini P, Borrello I, Bronte V. 2006. Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression. Semin Cancer Biol 16:53-65.
    • (2006) Semin Cancer Biol , vol.16 , pp. 53-65
    • Serafini, P.1    Borrello, I.2    Bronte, V.3
  • 12
    • 28044445899 scopus 로고    scopus 로고
    • Role of immature myeloid cells in mechanisms of immune evasion in cancer
    • Kusmartsev S, Gabrilovich DI. 2006. Role of immature myeloid cells in mechanisms of immune evasion in cancer. Cancer Immunol Immunother 55:237-245.
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 237-245
    • Kusmartsev, S.1    Gabrilovich, D.I.2
  • 14
    • 4544220702 scopus 로고    scopus 로고
    • + myeloid cells and anergy of T lymphocytes participate in hyporesponsiveness of the lung-associated immune system during acute toxoplasmosis
    • + myeloid cells and anergy of T lymphocytes participate in hyporesponsiveness of the lung-associated immune system during acute toxoplasmosis. Infect Immun 72:5487-5492.
    • (2004) Infect Immun , vol.72 , pp. 5487-5492
    • Voisin, M.B.1    Buzoni-Gatel, D.2    Bout, D.3    Velge-Roussel, F.4
  • 21
    • 84884556145 scopus 로고    scopus 로고
    • History of myeloid-derived suppressor cells
    • Talmadge JE, Gabrilovich DI. 2013. History of myeloid-derived suppressor cells. Nat Rev Cancer 13:739-752.
    • (2013) Nat Rev Cancer , vol.13 , pp. 739-752
    • Talmadge, J.E.1    Gabrilovich, D.I.2
  • 25
    • 29744454134 scopus 로고    scopus 로고
    • Myeloid dendritic cell precursors generated from bone marrow suppress T cell responses via cell contact and nitric oxide production in vitro
    • Rossner S, Voigtlander C, Wiethe C, Hanig J, Seifarth C, Lutz MB. 2005. Myeloid dendritic cell precursors generated from bone marrow suppress T cell responses via cell contact and nitric oxide production in vitro. Eur J Immunol 35:3533-3544.
    • (2005) Eur J Immunol , vol.35 , pp. 3533-3544
    • Rossner, S.1    Voigtlander, C.2    Wiethe, C.3    Hanig, J.4    Seifarth, C.5    Lutz, M.B.6
  • 26
    • 33845534522 scopus 로고    scopus 로고
    • Effect of tumor-derived cytokines and growth factors on differentiation and immune suppressive features of myeloid cells in cancer
    • Kusmartsev S, Gabrilovich DI. 2006. Effect of tumor-derived cytokines and growth factors on differentiation and immune suppressive features of myeloid cells in cancer. Cancer Metastasis Rev 25:323-331.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 323-331
    • Kusmartsev, S.1    Gabrilovich, D.I.2
  • 27
    • 0042591427 scopus 로고    scopus 로고
    • All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination
    • Kusmartsev S, Cheng F, Yu B, Nefedova Y, Sotomayor E, Lush R, Gabrilovich D. 2003. All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination. Cancer Res 63:4441-4449.
    • (2003) Cancer Res , vol.63 , pp. 4441-4449
    • Kusmartsev, S.1    Cheng, F.2    Yu, B.3    Nefedova, Y.4    Sotomayor, E.5    Lush, R.6    Gabrilovich, D.7
  • 29
    • 0041850021 scopus 로고    scopus 로고
    • Inhibition of myeloid cell differentiation in cancer: the role of reactive oxygen species
    • Kusmartsev S, Gabrilovich DI. 2003. Inhibition of myeloid cell differentiation in cancer: the role of reactive oxygen species. J Leukoc Biol 74:186-196.
    • (2003) J Leukoc Biol , vol.74 , pp. 186-196
    • Kusmartsev, S.1    Gabrilovich, D.I.2
  • 30
    • 67649404131 scopus 로고    scopus 로고
    • Blood monocytes: development, heterogeneity, and relationship with dendritic cells
    • Auffray C, Sieweke MH, Geissmann F. 2009. Blood monocytes: development, heterogeneity, and relationship with dendritic cells. Annu Rev Immunol 27:669-692.
    • (2009) Annu Rev Immunol , vol.27 , pp. 669-692
    • Auffray, C.1    Sieweke, M.H.2    Geissmann, F.3
  • 32
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumor-bearing mice
    • Youn JI, Nagaraj S, Collazo M, Gabrilovich DI. 2008. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol 181: 5791-5802.
    • (2008) J Immunol , vol.181 , pp. 5791-5802
    • Youn, J.I.1    Nagaraj, S.2    Collazo, M.3    Gabrilovich, D.I.4
  • 33
    • 77956205298 scopus 로고    scopus 로고
    • CD49d is a new marker for distinct myeloid-derived suppressor cell subpopulations in mice
    • Haile LA, Gamrekelashvili J, Manns MP, Korangy F, Greten TF. 2010. CD49d is a new marker for distinct myeloid-derived suppressor cell subpopulations in mice. J Immunol 185:203-210.
    • (2010) J Immunol , vol.185 , pp. 203-210
    • Haile, L.A.1    Gamrekelashvili, J.2    Manns, M.P.3    Korangy, F.4    Greten, T.F.5
  • 37
    • 84858202940 scopus 로고    scopus 로고
    • Aptamer-mediated blockade of IL4Ra triggers apoptosis of MDSCs and limits tumor progression
    • Roth F, De La Fuente AC, Vella JL, Zoso A, Inverardi L, Serafini P. 2012. Aptamer-mediated blockade of IL4Ra triggers apoptosis of MDSCs and limits tumor progression. Cancer Res 72:1373-1383.
    • (2012) Cancer Res , vol.72 , pp. 1373-1383
    • Roth, F.1    De La Fuente, A.C.2    Vella, J.L.3    Zoso, A.4    Inverardi, L.5    Serafini, P.6
  • 38
    • 80054899779 scopus 로고    scopus 로고
    • Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils
    • Galli SJ, Borregaard N, Wynn TA. 2011. Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils. Nat Immunol 12:1035-1044.
    • (2011) Nat Immunol , vol.12 , pp. 1035-1044
    • Galli, S.J.1    Borregaard, N.2    Wynn, T.A.3
  • 40
    • 77956976681 scopus 로고    scopus 로고
    • Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
    • Biswas SK, Mantovani A. 2010. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol 11: 889-896.
    • (2010) Nat Immunol , vol.11 , pp. 889-896
    • Biswas, S.K.1    Mantovani, A.2
  • 44
    • 84876800337 scopus 로고    scopus 로고
    • Macrophage biology in development, homeostasis and disease
    • Wynn TA, Chawla A, Pollard JW. 2013. Macrophage biology in development, homeostasis and disease. Nature 496:445-455.
    • (2013) Nature , vol.496 , pp. 445-455
    • Wynn, T.A.1    Chawla, A.2    Pollard, J.W.3
  • 46
    • 38449112889 scopus 로고    scopus 로고
    • The role of chemokines in neutrophil biology
    • Kobayashi Y. 2008. The role of chemokines in neutrophil biology. Front Biosci 13:2400-2407.
    • (2008) Front Biosci , vol.13 , pp. 2400-2407
    • Kobayashi, Y.1
  • 48
    • 84855301911 scopus 로고    scopus 로고
    • Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice
    • Youn JI, Collazo M, Shalova IN, Biswas SK, Gabrilovich DI. 2012. Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice. J Leukoc Biol 91:167-181.
    • (2012) J Leukoc Biol , vol.91 , pp. 167-181
    • Youn, J.I.1    Collazo, M.2    Shalova, I.N.3    Biswas, S.K.4    Gabrilovich, D.I.5
  • 52
    • 84916908891 scopus 로고    scopus 로고
    • Human fibrocytic myeloid-derived suppressor cells express IDO and promote tolerance via Treg-cell expansion
    • Zoso A, Mazza EM, Bicciato S, Mandruzzato S, Bronte V, Serafini P, Inverardi L. 2014. Human fibrocytic myeloid-derived suppressor cells express IDO and promote tolerance via Treg-cell expansion. Eur J Immunol 44:3307-3319.
    • (2014) Eur J Immunol , vol.44 , pp. 3307-3319
    • Zoso, A.1    Mazza, E.M.2    Bicciato, S.3    Mandruzzato, S.4    Bronte, V.5    Serafini, P.6    Inverardi, L.7
  • 53
    • 84887197816 scopus 로고    scopus 로고
    • Fibrocytes represent a novel MDSC subset circulating in patients with metastatic cancer
    • Zhang H, Maric I, DiPrima MJ, Khan J, Orentas RJ, Kaplan RN, Mackall CL. 2013. Fibrocytes represent a novel MDSC subset circulating in patients with metastatic cancer. Blood 122:1105-1113.
    • (2013) Blood , vol.122 , pp. 1105-1113
    • Zhang, H.1    Maric, I.2    DiPrima, M.J.3    Khan, J.4    Orentas, R.J.5    Kaplan, R.N.6    Mackall, C.L.7
  • 54
    • 84927727444 scopus 로고    scopus 로고
    • Deficiency of Kruppel-like factor KLF4 in myeloidderived suppressor cells inhibits tumor pulmonary metastasis in mice accompanied by decreased fibrocytes
    • Shi Y, Ou L, Han S, Li M, Pena MM, Pena EA, Liu C, Nagarkatti M, Fan D, Ai W. 2014. Deficiency of Kruppel-like factor KLF4 in myeloidderived suppressor cells inhibits tumor pulmonary metastasis in mice accompanied by decreased fibrocytes. Oncogenesis 3:e129. doi:10.1038/oncsis.2014.44.
    • (2014) Oncogenesis , vol.3
    • Shi, Y.1    Ou, L.2    Han, S.3    Li, M.4    Pena, M.M.5    Pena, E.A.6    Liu, C.7    Nagarkatti, M.8    Fan, D.9    Ai, W.10
  • 56
    • 54849440346 scopus 로고    scopus 로고
    • Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
    • Diaz-Montero CM, Salem ML, Nishimura MI, Garrett-Mayer E, Cole DJ, Montero AJ. 2009. Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol Immunother 58:49-59.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 49-59
    • Diaz-Montero, C.M.1    Salem, M.L.2    Nishimura, M.I.3    Garrett-Mayer, E.4    Cole, D.J.5    Montero, A.J.6
  • 58
    • 60549088732 scopus 로고    scopus 로고
    • Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes
    • Rodriguez PC, Ernstoff MS, Hernandez C, Atkins M, Zabaleta J, Sierra R, Ochoa AC. 2009. Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes. Cancer Res 69:1553-1560.
    • (2009) Cancer Res , vol.69 , pp. 1553-1560
    • Rodriguez, P.C.1    Ernstoff, M.S.2    Hernandez, C.3    Atkins, M.4    Zabaleta, J.5    Sierra, R.6    Ochoa, A.C.7
  • 59
    • 80054102628 scopus 로고    scopus 로고
    • Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13
    • Gabitass RF, Annels NE, Stocken DD, Pandha HA, Middleton GW. 2011. Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13. Cancer Immunol Immunother 60:1419-1430.
    • (2011) Cancer Immunol Immunother , vol.60 , pp. 1419-1430
    • Gabitass, R.F.1    Annels, N.E.2    Stocken, D.D.3    Pandha, H.A.4    Middleton, G.W.5
  • 66
    • 84877766429 scopus 로고    scopus 로고
    • Granulocytic myeloid-derived suppressor cells are cryosensitive and their frequency does not correlate with serum concentrations of colonystimulating factors in head and neck cancer
    • Trellakis S, BruderekK, Hutte J, ElianM, Hoffmann TK, Lang S, Brandau S. 2013. Granulocytic myeloid-derived suppressor cells are cryosensitive and their frequency does not correlate with serum concentrations of colonystimulating factors in head and neck cancer. Innate Immun 19:328-336.
    • (2013) Innate Immun , vol.19 , pp. 328-336
    • Trellakis, S.1    Bruderek, K.2    Hutte, J.3    Elian, M.4    Hoffmann, T.K.5    Lang, S.6    Brandau, S.7
  • 68
    • 84924922045 scopus 로고    scopus 로고
    • Correlation between frequencies of blood monocytic myeloid-derived suppressor cells, regulatory T cells and negative prognostic markers in patients with castration-resistant metastatic prostate cancer
    • Idorn M, Kollgaard T, Kongsted P, Sengelov L, Thor Straten P. 2014. Correlation between frequencies of blood monocytic myeloid-derived suppressor cells, regulatory T cells and negative prognostic markers in patients with castration-resistant metastatic prostate cancer. Cancer Immunol Immunother 63:1177-1187.
    • (2014) Cancer Immunol Immunother , vol.63 , pp. 1177-1187
    • Idorn, M.1    Kollgaard, T.2    Kongsted, P.3    Sengelov, L.4    Thor Straten, P.5
  • 69
    • 84929051791 scopus 로고    scopus 로고
    • Infiltration of alternatively activated macrophages in cancer tissue is associated with MDSC and Th2 polarization in patients with esophageal cancer
    • Gao J, Wu Y, Su Z, Amoah Barnie P, Jiao Z, Bie Q, Lu L, Wang S, Xu H. 2014. Infiltration of alternatively activated macrophages in cancer tissue is associated with MDSC and Th2 polarization in patients with esophageal cancer. PLoS One 9:e104453. doi:10.1371/journal.pone.0104453.
    • (2014) PLoS One , vol.9
    • Gao, J.1    Wu, Y.2    Su, Z.3    Amoah Barnie, P.4    Jiao, Z.5    Bie, Q.6    Lu, L.7    Wang, S.8    Xu, H.9
  • 73
    • 71749088821 scopus 로고    scopus 로고
    • CCL2 and interleukin-6 promote survival of human CD11b+ peripheral blood mononuclear cells and induce M2-type macrophage polarization
    • Roca H, Varsos ZS, Sud S, Craig MJ, Ying C, Pienta KJ. 2009. CCL2 and interleukin-6 promote survival of human CD11b+ peripheral blood mononuclear cells and induce M2-type macrophage polarization. J Biol Chem 284:34342-34354.
    • (2009) J Biol Chem , vol.284 , pp. 34342-34354
    • Roca, H.1    Varsos, Z.S.2    Sud, S.3    Craig, M.J.4    Ying, C.5    Pienta, K.J.6
  • 74
    • 42349094504 scopus 로고    scopus 로고
    • Tumor escape mechanism governed by myeloid-derived suppressor cells
    • Nagaraj S, Gabrilovich DI. 2008. Tumor escape mechanism governed by myeloid-derived suppressor cells. Cancer Res 68:2561-2563.
    • (2008) Cancer Res , vol.68 , pp. 2561-2563
    • Nagaraj, S.1    Gabrilovich, D.I.2
  • 76
    • 19344377474 scopus 로고    scopus 로고
    • GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2, 3-dioxygenase
    • Munn DH, Sharma MD, Baban B, Harding HP, Zhang Y, Ron D, Mellor AL. 2005. GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2, 3-dioxygenase. Immunity 22:633-642.
    • (2005) Immunity , vol.22 , pp. 633-642
    • Munn, D.H.1    Sharma, M.D.2    Baban, B.3    Harding, H.P.4    Zhang, Y.5    Ron, D.6    Mellor, A.L.7
  • 77
    • 78650547540 scopus 로고    scopus 로고
    • An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis
    • Quintana FJ, Murugaiyan G, Farez MF, Mitsdoerffer M, Tukpah AM, Burns EJ, Weiner HL. 2010. An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A 107:20768-20773.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 20768-20773
    • Quintana, F.J.1    Murugaiyan, G.2    Farez, M.F.3    Mitsdoerffer, M.4    Tukpah, A.M.5    Burns, E.J.6    Weiner, H.L.7
  • 78
    • 84911470410 scopus 로고    scopus 로고
    • Breaking immunotolerance of tumors: a new perspective for dendritic cell therapy
    • Rolinski J, Hus I. 2014. Breaking immunotolerance of tumors: a new perspective for dendritic cell therapy. J Immunotoxicol 11:311-318.
    • (2014) J Immunotoxicol , vol.11 , pp. 311-318
    • Rolinski, J.1    Hus, I.2
  • 79
    • 81255138408 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase expression in human cancers: clinical and immunologic perspectives
    • Godin-Ethier J, Hanafi LA, Piccirillo CA, Lapointe R. 2011. Indoleamine 2, 3-dioxygenase expression in human cancers: clinical and immunologic perspectives. Clin Cancer Res 17:6985-6991.
    • (2011) Clin Cancer Res , vol.17 , pp. 6985-6991
    • Godin-Ethier, J.1    Hanafi, L.A.2    Piccirillo, C.A.3    Lapointe, R.4
  • 80
    • 23444456772 scopus 로고    scopus 로고
    • Regulation of immune responses by L-arginine metabolism
    • Bronte V, Zanovello P. 2005. Regulation of immune responses by L-arginine metabolism. Nat Rev Immunol 5:641-654.
    • (2005) Nat Rev Immunol , vol.5 , pp. 641-654
    • Bronte, V.1    Zanovello, P.2
  • 82
    • 0142148325 scopus 로고    scopus 로고
    • Nitric oxide regulation of human peripheral blood mononuclear cells: critical time dependence and selectivity for cytokine versus chemokine expression
    • Macphail SE, Gibney CA, Brooks BM, Booth CG, Flanagan BF, Coleman JW. 2003. Nitric oxide regulation of human peripheral blood mononuclear cells: critical time dependence and selectivity for cytokine versus chemokine expression. J Immunol 171:4809-4815.
    • (2003) J Immunol , vol.171 , pp. 4809-4815
    • Macphail, S.E.1    Gibney, C.A.2    Brooks, B.M.3    Booth, C.G.4    Flanagan, B.F.5    Coleman, J.W.6
  • 83
    • 4544309074 scopus 로고    scopus 로고
    • TCR ζ-chain downregulation: curtailing an excessive inflammatory immune response
    • Baniyash M. 2004. TCR ζ-chain downregulation: curtailing an excessive inflammatory immune response. Nat Rev Immunol 4:675-687.
    • (2004) Nat Rev Immunol , vol.4 , pp. 675-687
    • Baniyash, M.1
  • 84
    • 33846933459 scopus 로고    scopus 로고
    • L-Arginine availability regulates T-lymphocyte cell-cycle progression
    • Rodriguez PC, Quiceno DG, Ochoa AC. 2007. L-Arginine availability regulates T-lymphocyte cell-cycle progression. Blood 109:1568-1573.
    • (2007) Blood , vol.109 , pp. 1568-1573
    • Rodriguez, P.C.1    Quiceno, D.G.2    Ochoa, A.C.3
  • 86
    • 84866916560 scopus 로고    scopus 로고
    • Metabolism of L-arginine by myeloid-derived suppressor cells in cancer: mechanisms of T cell suppression and therapeutic perspectives
    • Raber P, Ochoa AC, Rodriguez PC. 2012. Metabolism of L-arginine by myeloid-derived suppressor cells in cancer: mechanisms of T cell suppression and therapeutic perspectives. Immunol Invest 41:614-634.
    • (2012) Immunol Invest , vol.41 , pp. 614-634
    • Raber, P.1    Ochoa, A.C.2    Rodriguez, P.C.3
  • 87
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology
    • Bedard K, Krause KH. 2007. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev 87:245-313.
    • (2007) Physiol Rev , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 89
    • 0035294392 scopus 로고    scopus 로고
    • Suppressed T-cell receptor zeta chain expression and cytokine production in pancreatic cancer patients
    • Schmielau J, Nalesnik MA, Finn OJ. 2001. Suppressed T-cell receptor zeta chain expression and cytokine production in pancreatic cancer patients. Clin Cancer Res 7(3 Suppl):933s-939s.
    • (2001) Clin Cancer Res , vol.7 , Issue.3 , pp. 933s-939s
    • Schmielau, J.1    Nalesnik, M.A.2    Finn, O.J.3
  • 90
    • 0029841427 scopus 로고    scopus 로고
    • Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 ζ chain of T-cell receptor complex and antigen-specific T-cell responses
    • Otsuji M, Kimura Y, Aoe T, Okamoto Y, Saito T. 1996. Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 ζ chain of T-cell receptor complex and antigen-specific T-cell responses. Proc Natl Acad Sci U S A 93:13119-13124.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 13119-13124
    • Otsuji, M.1    Kimura, Y.2    Aoe, T.3    Okamoto, Y.4    Saito, T.5
  • 91
    • 0346100520 scopus 로고    scopus 로고
    • Peroxynitrite reactivity with amino acids and proteins
    • Alvarez B, Radi R. 2003. Peroxynitrite reactivity with amino acids and proteins. Amino Acids 25:295-311.
    • (2003) Amino Acids , vol.25 , pp. 295-311
    • Alvarez, B.1    Radi, R.2
  • 92
    • 44449157285 scopus 로고    scopus 로고
    • Conversion of tyrosine to the inflammation-associated analog 3'-nitrotyrosine at either TCR-or MHCcontact positions can profoundly affect recognition of the MHC class Irestricted epitope of lymphocytic choriomeningitis virus glycoprotein 33 by CD8 T cells
    • Hardy LL, Wick DA, Webb JR. 2008. Conversion of tyrosine to the inflammation-associated analog 3'-nitrotyrosine at either TCR-or MHCcontact positions can profoundly affect recognition of the MHC class Irestricted epitope of lymphocytic choriomeningitis virus glycoprotein 33 by CD8 T cells. J Immunol 180:5956-5962.
    • (2008) J Immunol , vol.180 , pp. 5956-5962
    • Hardy, L.L.1    Wick, D.A.2    Webb, J.R.3
  • 93
    • 77950829023 scopus 로고    scopus 로고
    • Mechanism of T cell tolerance induced by myeloid-derived suppressor cells
    • Nagaraj S, Schrum AG, Cho HI, Celis E, Gabrilovich DI. 2010. Mechanism of T cell tolerance induced by myeloid-derived suppressor cells. J Immunol 184:3106-3116.
    • (2010) J Immunol , vol.184 , pp. 3106-3116
    • Nagaraj, S.1    Schrum, A.G.2    Cho, H.I.3    Celis, E.4    Gabrilovich, D.I.5
  • 94
  • 98
    • 4344622055 scopus 로고    scopus 로고
    • Kip1 act in synergy to alter the sensitivity of naive T cells to TGF-β-mediated G1 arrest through modulation of IL-2 responsiveness
    • Kip1 act in synergy to alter the sensitivity of naive T cells to TGF-β-mediated G1 arrest through modulation of IL-2 responsiveness. J Immunol 173:3093-3102.
    • (2004) J Immunol , vol.173 , pp. 3093-3102
    • Wolfraim, L.A.1    Walz, T.M.2    James, Z.3    Fernandez, T.4    Letterio, J.J.5
  • 99
    • 0027392761 scopus 로고
    • Transforming growth factor β and cyclosporin A inhibit the inducible activity of the interleukin-2 gene in T cells through a noncanonical octamer-binding site
    • Brabletz T, Pfeuffer I, Schorr E, Siebelt F, Wirth T, Serfling E. 1993. Transforming growth factor β and cyclosporin A inhibit the inducible activity of the interleukin-2 gene in T cells through a noncanonical octamer-binding site. Mol Cell Biol 13:1155-1162.
    • (1993) Mol Cell Biol , vol.13 , pp. 1155-1162
    • Brabletz, T.1    Pfeuffer, I.2    Schorr, E.3    Siebelt, F.4    Wirth, T.5    Serfling, E.6
  • 101
    • 48549085973 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells
    • Serafini P, Mgebroff S, Noonan K, Borrello I. 2008. Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells. Cancer Res 68:5439-5449.
    • (2008) Cancer Res , vol.68 , pp. 5439-5449
    • Serafini, P.1    Mgebroff, S.2    Noonan, K.3    Borrello, I.4
  • 102
    • 79959271214 scopus 로고    scopus 로고
    • Plasticity of human Th17 cells and iTregs is orchestrated by different subsets of myeloid cells
    • Hoechst B, Gamrekelashvili J, Manns MP, Greten TF, Korangy F. 2011. Plasticity of human Th17 cells and iTregs is orchestrated by different subsets of myeloid cells. Blood 117:6532-6541.
    • (2011) Blood , vol.117 , pp. 6532-6541
    • Hoechst, B.1    Gamrekelashvili, J.2    Manns, M.P.3    Greten, T.F.4    Korangy, F.5
  • 103
    • 34548805636 scopus 로고    scopus 로고
    • Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response
    • Sinha P, Clements VK, Bunt SK, Albelda SM, Ostrand-Rosenberg S. 2007. Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response. J Immunol 179:977-983.
    • (2007) J Immunol , vol.179 , pp. 977-983
    • Sinha, P.1    Clements, V.K.2    Bunt, S.K.3    Albelda, S.M.4    Ostrand-Rosenberg, S.5
  • 110
    • 65249138393 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: linking inflammation and cancer
    • Ostrand-Rosenberg S, Sinha P. 2009. Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol 182:4499-4506.
    • (2009) J Immunol , vol.182 , pp. 4499-4506
    • Ostrand-Rosenberg, S.1    Sinha, P.2
  • 114
    • 79958052123 scopus 로고    scopus 로고
    • MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy
    • Finke J, Ko J, Rini B, Rayman P, Ireland J, Cohen P. 2011. MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy. Int Immunopharmacol 11:856-861.
    • (2011) Int Immunopharmacol , vol.11 , pp. 856-861
    • Finke, J.1    Ko, J.2    Rini, B.3    Rayman, P.4    Ireland, J.5    Cohen, P.6
  • 117
    • 53349125963 scopus 로고    scopus 로고
    • Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells
    • Sinha P, Okoro C, Foell D, Freeze HH, Ostrand-Rosenberg S, Srikrishna G. 2008. Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells. J Immunol 181:4666-4675.
    • (2008) J Immunol , vol.181 , pp. 4666-4675
    • Sinha, P.1    Okoro, C.2    Foell, D.3    Freeze, H.H.4    Ostrand-Rosenberg, S.5    Srikrishna, G.6
  • 119
    • 84883609975 scopus 로고    scopus 로고
    • A mutual activation loop between breast cancer cells and myeloid-derived suppressor cells facilitates spontaneous metastasis through IL-6 transsignaling in a murine model
    • Oh K, Lee OY, Shon SY, Nam O, Ryu PM, Seo MW, Lee DS. 2013. A mutual activation loop between breast cancer cells and myeloid-derived suppressor cells facilitates spontaneous metastasis through IL-6 transsignaling in a murine model. Breast Cancer Res 15:R79. doi:10.1186/bcr3473.
    • (2013) Breast Cancer Res , vol.15
    • Oh, K.1    Lee, O.Y.2    Shon, S.Y.3    Nam, O.4    Ryu, P.M.5    Seo, M.W.6    Lee, D.S.7
  • 120
    • 33751504690 scopus 로고    scopus 로고
    • Tumourmediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
    • Hiratsuka S, Watanabe A, Aburatani H, Maru Y. 2006. Tumourmediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nat Cell Biol 8:1369-1375.
    • (2006) Nat Cell Biol , vol.8 , pp. 1369-1375
    • Hiratsuka, S.1    Watanabe, A.2    Aburatani, H.3    Maru, Y.4
  • 121
    • 80053336355 scopus 로고    scopus 로고
    • Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cells infiltrating the primary tumor
    • Toh B, Wang X, Keeble J, Sim WJ, Khoo K, Wong WC, Kato M, Prevost-Blondel A, Thiery JP, Abastado JP. 2011. Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cells infiltrating the primary tumor. PLoS Biol 9:e1001162. doi:10.1371/journal.pbio.1001162.
    • (2011) PLoS Biol , vol.9
    • Toh, B.1    Wang, X.2    Keeble, J.3    Sim, W.J.4    Khoo, K.5    Wong, W.C.6    Kato, M.7    Prevost-Blondel, A.8    Thiery, J.P.9    Abastado, J.P.10
  • 122
    • 84920742715 scopus 로고    scopus 로고
    • High-mobility group box 1: a novel inducer of the epithelial-mesenchymal transition in colorectal carcinoma
    • Zhu L, Li X, Chen Y, Fang J, Ge Z. 2015. High-mobility group box 1: a novel inducer of the epithelial-mesenchymal transition in colorectal carcinoma. Cancer Lett 357:527-534.
    • (2015) Cancer Lett , vol.357 , pp. 527-534
    • Zhu, L.1    Li, X.2    Chen, Y.3    Fang, J.4    Ge, Z.5
  • 125
    • 84875738283 scopus 로고    scopus 로고
    • Serum levels of vascular endothelial growth factor are increased and correlate with malnutrition, immunosuppression involving MDSCs and systemic inflammation in patients with cancer of the digestive system
    • Nakamura I, Shibata M, Gonda K, Yazawa T, Shimura T, Anazawa T, Suzuki S, Sakurai K, Koyama Y, Ohto H, Tomita R, Gotoh M, Takenoshita S. 2013. Serum levels of vascular endothelial growth factor are increased and correlate with malnutrition, immunosuppression involving MDSCs and systemic inflammation in patients with cancer of the digestive system. Oncol Lett 5:1682-1686.
    • (2013) Oncol Lett , vol.5 , pp. 1682-1686
    • Nakamura, I.1    Shibata, M.2    Gonda, K.3    Yazawa, T.4    Shimura, T.5    Anazawa, T.6    Suzuki, S.7    Sakurai, K.8    Koyama, Y.9    Ohto, H.10    Tomita, R.11    Gotoh, M.12    Takenoshita, S.13
  • 127
    • 0035511870 scopus 로고    scopus 로고
    • Secretion of GM-CSF and M-CSF by human renal cell carcinomas of different histologic types
    • Gerharz CD, Reinecke P, Schneider EM, Schmitz M, Gabbert HE. 2001. Secretion of GM-CSF and M-CSF by human renal cell carcinomas of different histologic types. Urology 58:821-827.
    • (2001) Urology , vol.58 , pp. 821-827
    • Gerharz, C.D.1    Reinecke, P.2    Schneider, E.M.3    Schmitz, M.4    Gabbert, H.E.5
  • 132
    • 84862150896 scopus 로고    scopus 로고
    • Tumor-derived granulocyte-macrophage colonystimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer
    • Bayne LJ, Beatty GL, Jhala N, Clark CE, Rhim AD, Stanger BZ, Vonderheide RH. 2012. Tumor-derived granulocyte-macrophage colonystimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer. Cancer Cell 21:822-835.
    • (2012) Cancer Cell , vol.21 , pp. 822-835
    • Bayne, L.J.1    Beatty, G.L.2    Jhala, N.3    Clark, C.E.4    Rhim, A.D.5    Stanger, B.Z.6    Vonderheide, R.H.7
  • 134
    • 4344590947 scopus 로고    scopus 로고
    • High-dose granulocyte-macrophage colony-stimulating factorproducing vaccines impair the immune response through the recruitment of myeloid suppressor cells
    • Serafini P, Carbley R, Noonan KA, Tan G, Bronte V, Borrello I. 2004. High-dose granulocyte-macrophage colony-stimulating factorproducing vaccines impair the immune response through the recruitment of myeloid suppressor cells. Cancer Res 64:6337-6343.
    • (2004) Cancer Res , vol.64 , pp. 6337-6343
    • Serafini, P.1    Carbley, R.2    Noonan, K.A.3    Tan, G.4    Bronte, V.5    Borrello, I.6
  • 135
  • 136
    • 0142250392 scopus 로고    scopus 로고
    • Targeted antiinterleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence
    • Trikha M, Corringham R, Klein B, Rossi JF. 2003. Targeted antiinterleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence. Clin Cancer Res 9:4653-4665.
    • (2003) Clin Cancer Res , vol.9 , pp. 4653-4665
    • Trikha, M.1    Corringham, R.2    Klein, B.3    Rossi, J.F.4
  • 140
    • 84908054077 scopus 로고    scopus 로고
    • HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloidderived suppressor cells
    • Parker KH, Sinha P, Horn LA, Clements VK, Yang H, Li J, Tracey KJ, Ostrand-Rosenberg S. 2014. HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloidderived suppressor cells. Cancer Res 74:5723-5733.
    • (2014) Cancer Res , vol.74 , pp. 5723-5733
    • Parker, K.H.1    Sinha, P.2    Horn, L.A.3    Clements, V.K.4    Yang, H.5    Li, J.6    Tracey, K.J.7    Ostrand-Rosenberg, S.8
  • 141
    • 84918573027 scopus 로고    scopus 로고
    • Tumor-derived osteopontin suppresses antitumor immunity by promoting extramedullary myelopoiesis
    • Kim EK, Jeon I, Seo H, Park YJ, Song B, Lee KA, Jang Y, Chung Y, Kang CY. 2014. Tumor-derived osteopontin suppresses antitumor immunity by promoting extramedullary myelopoiesis. Cancer Res 74:6705-6716.
    • (2014) Cancer Res , vol.74 , pp. 6705-6716
    • Kim, E.K.1    Jeon, I.2    Seo, H.3    Park, Y.J.4    Song, B.5    Lee, K.A.6    Jang, Y.7    Chung, Y.8    Kang, C.Y.9
  • 143
    • 33744548730 scopus 로고    scopus 로고
    • Signal transduction of inflammatory cytokines and tumor development
    • Yoshimura A. 2006. Signal transduction of inflammatory cytokines and tumor development. Cancer Sci 97:439-447.
    • (2006) Cancer Sci , vol.97 , pp. 439-447
    • Yoshimura, A.1
  • 144
    • 17044366637 scopus 로고    scopus 로고
    • STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion
    • Kusmartsev S, Gabrilovich DI. 2005. STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion. J Immunol 174: 4880-4891.
    • (2005) J Immunol , vol.174 , pp. 4880-4891
    • Kusmartsev, S.1    Gabrilovich, D.I.2
  • 145
    • 0034669980 scopus 로고    scopus 로고
    • IFN-γ can promote tumor evasion of the immune system in vivo by down-regulating cellular levels of an endogenous tumor antigen
    • Beatty GL, Paterson Y. 2000. IFN-γ can promote tumor evasion of the immune system in vivo by down-regulating cellular levels of an endogenous tumor antigen. J Immunol 165:5502-5508.
    • (2000) J Immunol , vol.165 , pp. 5502-5508
    • Beatty, G.L.1    Paterson, Y.2
  • 146
    • 0036521607 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and target-gene expression during human monocyte/macrophage differentiation
    • Lehtonen A, Matikainen S, Miettinen M, Julkunen I. 2002. Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and target-gene expression during human monocyte/macrophage differentiation. J Leukoc Biol 71:511-519.
    • (2002) J Leukoc Biol , vol.71 , pp. 511-519
    • Lehtonen, A.1    Matikainen, S.2    Miettinen, M.3    Julkunen, I.4
  • 148
    • 65549129226 scopus 로고    scopus 로고
    • Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells
    • Xin H, Zhang C, Herrmann A, Du Y, Figlin R, Yu H. 2009. Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells. Cancer Res 69:2506-2513.
    • (2009) Cancer Res , vol.69 , pp. 2506-2513
    • Xin, H.1    Zhang, C.2    Herrmann, A.3    Du, Y.4    Figlin, R.5    Yu, H.6
  • 150
    • 0037111416 scopus 로고    scopus 로고
    • Resistance to metastatic disease in STAT6-deficient mice requires hemopoietic and nonhemopoietic cells and is IFN-γ dependent
    • Ostrand-Rosenberg S, Clements VK, Terabe M, Park JM, Berzofsky JA, Dissanayake SK. 2002. Resistance to metastatic disease in STAT6-deficient mice requires hemopoietic and nonhemopoietic cells and is IFN-γ dependent. J Immunol 169:5796-5804.
    • (2002) J Immunol , vol.169 , pp. 5796-5804
    • Ostrand-Rosenberg, S.1    Clements, V.K.2    Terabe, M.3    Park, J.M.4    Berzofsky, J.A.5    Dissanayake, S.K.6
  • 151
    • 74049097839 scopus 로고    scopus 로고
    • Stat 6-dependent induction of myeloid derived suppressor cells after physical injury regulates nitric oxide response to endotoxin
    • Munera V, Popovic PJ, Bryk J, Pribis J, Caba D, Matta BM, Zenati M, Ochoa JB. 2010. Stat 6-dependent induction of myeloid derived suppressor cells after physical injury regulates nitric oxide response to endotoxin. Ann Surg 251:120-126.
    • (2010) Ann Surg , vol.251 , pp. 120-126
    • Munera, V.1    Popovic, P.J.2    Bryk, J.3    Pribis, J.4    Caba, D.5    Matta, B.M.6    Zenati, M.7    Ochoa, J.B.8
  • 153
    • 77954399377 scopus 로고    scopus 로고
    • Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloidderived suppressor cell function
    • Sander LE, Sackett SD, Dierssen U, Beraza N, Linke RP, Muller M, Blander JM, Tacke F, Trautwein C. 2010. Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloidderived suppressor cell function. J Exp Med 207:1453-1464.
    • (2010) J Exp Med , vol.207 , pp. 1453-1464
    • Sander, L.E.1    Sackett, S.D.2    Dierssen, U.3    Beraza, N.4    Linke, R.P.5    Muller, M.6    Blander, J.M.7    Tacke, F.8    Trautwein, C.9
  • 156
    • 0026501412 scopus 로고
    • Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6
    • Natsuka S, Akira S, Nishio Y, Hashimoto S, Sugita T, Isshiki H, Kishimoto T. 1992. Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6. Blood 79:460-466.
    • (1992) Blood , vol.79 , pp. 460-466
    • Natsuka, S.1    Akira, S.2    Nishio, Y.3    Hashimoto, S.4    Sugita, T.5    Isshiki, H.6    Kishimoto, T.7
  • 157
    • 0033198185 scopus 로고    scopus 로고
    • A composite C/EBP binding site is essential for the activity of the promoter of the IL-3/IL-5/granulocyte-macrophage colonystimulating factor receptor βc gene
    • van Dijk TB, Baltus B, Raaijmakers JA, Lammers JW, Koenderman L, de Groot RP. 1999. A composite C/EBP binding site is essential for the activity of the promoter of the IL-3/IL-5/granulocyte-macrophage colonystimulating factor receptor βc gene. J Immunol 163:2674-2680.
    • (1999) J Immunol , vol.163 , pp. 2674-2680
    • van Dijk, T.B.1    Baltus, B.2    Raaijmakers, J.A.3    Lammers, J.W.4    Koenderman, L.5    de Groot, R.P.6
  • 158
    • 84873662942 scopus 로고    scopus 로고
    • C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver
    • Chikka MR, McCabe DD, Tyra HM, Rutkowski DT. 2013. C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver. J Biol Chem 288: 4405-4415.
    • (2013) J Biol Chem , vol.288 , pp. 4405-4415
    • Chikka, M.R.1    McCabe, D.D.2    Tyra, H.M.3    Rutkowski, D.T.4
  • 160
    • 67149115417 scopus 로고    scopus 로고
    • Inflammation enhances myeloid-derived suppressor cell crosstalk by signaling through Toll-like receptor 4
    • Bunt SK, Clements VK, Hanson EM, Sinha P, Ostrand-Rosenberg S. 2009. Inflammation enhances myeloid-derived suppressor cell crosstalk by signaling through Toll-like receptor 4. J Leukoc Biol 85:996-1004.
    • (2009) J Leukoc Biol , vol.85 , pp. 996-1004
    • Bunt, S.K.1    Clements, V.K.2    Hanson, E.M.3    Sinha, P.4    Ostrand-Rosenberg, S.5
  • 161
    • 70350536358 scopus 로고    scopus 로고
    • Myeloidderived suppressor cell activation by combined LPS and IFN-γ treatment impairs DC development
    • Greifenberg V, Ribechini E, Rössner S, Lutz MB. 2009. Myeloidderived suppressor cell activation by combined LPS and IFN-γ treatment impairs DC development. Eur J Immunol 39:2865-2876.
    • (2009) Eur J Immunol , vol.39 , pp. 2865-2876
    • Greifenberg, V.1    Ribechini, E.2    Rössner, S.3    Lutz, M.B.4
  • 163
    • 84886812974 scopus 로고    scopus 로고
    • Down-regulation of PLCγ2-β-catenin pathway promotes activation and expansion of myeloid-derived suppressor cells in cancer
    • Capietto AH, Kim S, Sanford DE, Linehan DC, Hikida M, Kumosaki T, Novack DV, Faccio R. 2013. Down-regulation of PLCγ2-β-catenin pathway promotes activation and expansion of myeloid-derived suppressor cells in cancer. J Exp Med 210:2257-2271.
    • (2013) J Exp Med , vol.210 , pp. 2257-2271
    • Capietto, A.H.1    Kim, S.2    Sanford, D.E.3    Linehan, D.C.4    Hikida, M.5    Kumosaki, T.6    Novack, D.V.7    Faccio, R.8
  • 164
    • 81555205674 scopus 로고    scopus 로고
    • Murine pancreatic adenocarcinoma dampens SHIP-1 expression and alters MDSC homeostasis and function
    • Pilon-Thomas S, Nelson N, Vohra N, Jerald M, Pendleton L, Szekeres K, Ghansah T. 2011. Murine pancreatic adenocarcinoma dampens SHIP-1 expression and alters MDSC homeostasis and function. PLoS One 6:e27729. doi:10.1371/journal.pone.0027729.
    • (2011) PLoS One , vol.6
    • Pilon-Thomas, S.1    Nelson, N.2    Vohra, N.3    Jerald, M.4    Pendleton, L.5    Szekeres, K.6    Ghansah, T.7
  • 165
    • 84875459382 scopus 로고    scopus 로고
    • Trp53 inactivation in the tumor microenvironment promotes tumor progression by expanding the immunosuppressive lymphoid-like stromal network
    • Guo G, Marrero L, Rodriguez P, Del Valle L, Ochoa A, Cui Y. 2013. Trp53 inactivation in the tumor microenvironment promotes tumor progression by expanding the immunosuppressive lymphoid-like stromal network. Cancer Res 73:1668-1675.
    • (2013) Cancer Res , vol.73 , pp. 1668-1675
    • Guo, G.1    Marrero, L.2    Rodriguez, P.3    Del Valle, L.4    Ochoa, A.5    Cui, Y.6
  • 166
    • 84893357722 scopus 로고    scopus 로고
    • MicroRNA-155 and MicroRNA-21 promote the expansion of functional myeloid-derived suppressor cells
    • Li L, Zhang J, Diao W, Wang D, Wei Y, Zhang CY, Zen K. 2014. MicroRNA-155 and MicroRNA-21 promote the expansion of functional myeloid-derived suppressor cells. J Immunol 192:1034-1043.
    • (2014) J Immunol , vol.192 , pp. 1034-1043
    • Li, L.1    Zhang, J.2    Diao, W.3    Wang, D.4    Wei, Y.5    Zhang, C.Y.6    Zen, K.7
  • 171
    • 77956680680 scopus 로고    scopus 로고
    • A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers
    • Kodumudi KN, Woan K, Gilvary DL, Sahakian E, Wei S, Djeu JY. 2010. A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers. Clin Cancer Res 16:4583-4594.
    • (2010) Clin Cancer Res , vol.16 , pp. 4583-4594
    • Kodumudi, K.N.1    Woan, K.2    Gilvary, D.L.3    Sahakian, E.4    Wei, S.5    Djeu, J.Y.6
  • 172
  • 176
    • 66149092730 scopus 로고    scopus 로고
    • G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models
    • Shojaei F, Wu X, Qu X, Kowanetz M, Yu L, Tan M, Meng YG, Ferrara N. 2009. G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models. Proc Natl Acad Sci U S A 106:6742-6747.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 6742-6747
    • Shojaei, F.1    Wu, X.2    Qu, X.3    Kowanetz, M.4    Yu, L.5    Tan, M.6    Meng, Y.G.7    Ferrara, N.8
  • 177
  • 178
    • 17144398046 scopus 로고    scopus 로고
    • Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection
    • Guiducci C, Vicari AP, Sangaletti S, Trinchieri G, Colombo MP. 2005. Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection. Cancer Res 65:3437-3446.
    • (2005) Cancer Res , vol.65 , pp. 3437-3446
    • Guiducci, C.1    Vicari, A.P.2    Sangaletti, S.3    Trinchieri, G.4    Colombo, M.P.5
  • 182
    • 77951754469 scopus 로고    scopus 로고
    • Direct and differential suppression of myeloidderived suppressor cell subsets by sunitinib is compartmentally constrained
    • Ko JS, Rayman P, Ireland J, Swaidani S, Li G, Bunting KD, Rini B, Finke JH, Cohen PA. 2010. Direct and differential suppression of myeloidderived suppressor cell subsets by sunitinib is compartmentally constrained. Cancer Res 70:3526-3536.
    • (2010) Cancer Res , vol.70 , pp. 3526-3536
    • Ko, J.S.1    Rayman, P.2    Ireland, J.3    Swaidani, S.4    Li, G.5    Bunting, K.D.6    Rini, B.7    Finke, J.H.8    Cohen, P.A.9
  • 183
    • 65549141834 scopus 로고    scopus 로고
    • The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies
    • Ozao-Choy J, Ma G, Kao J, Wang GX, Meseck M, Sung M, Schwartz M, Divino CM, Pan PY, Chen SH. 2009. The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies. Cancer Res 69:2514-2522.
    • (2009) Cancer Res , vol.69 , pp. 2514-2522
    • Ozao-Choy, J.1    Ma, G.2    Kao, J.3    Wang, G.X.4    Meseck, M.5    Sung, M.6    Schwartz, M.7    Divino, C.M.8    Pan, P.Y.9    Chen, S.H.10
  • 185
    • 34249300128 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes tumor progression by inducing myeloidderived suppressor cells
    • Sinha P, Clements VK, Fulton AM, Ostrand-Rosenberg S. 2007. Prostaglandin E2 promotes tumor progression by inducing myeloidderived suppressor cells. Cancer Res 67:4507-4513.
    • (2007) Cancer Res , vol.67 , pp. 4507-4513
    • Sinha, P.1    Clements, V.K.2    Fulton, A.M.3    Ostrand-Rosenberg, S.4
  • 187
    • 77956473075 scopus 로고    scopus 로고
    • COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloidderived suppressor cells in mesothelioma. Celecoxib influences MDSC function
    • Veltman JD, Lambers ME, van Nimwegen M, Hendriks RW, Hoogsteden HC, Aerts JG, Hegmans JP. 2010. COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloidderived suppressor cells in mesothelioma. Celecoxib influences MDSC function. BMC Cancer 10:464. doi:10.1186/1471-2407-10-464.
    • (2010) BMC Cancer , vol.10 , pp. 464
    • Veltman, J.D.1    Lambers, M.E.2    van Nimwegen, M.3    Hendriks, R.W.4    Hoogsteden, H.C.5    Aerts, J.G.6    Hegmans, J.P.7
  • 188
    • 33751531874 scopus 로고    scopus 로고
    • Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function
    • Serafini P, Meckel K, Kelso M, Noonan K, Califano J, Koch W, Dolcetti L, Bronte V, Borrello I. 2006. Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function. J Exp Med 203:2691-2702.
    • (2006) J Exp Med , vol.203 , pp. 2691-2702
    • Serafini, P.1    Meckel, K.2    Kelso, M.3    Noonan, K.4    Califano, J.5    Koch, W.6    Dolcetti, L.7    Bronte, V.8    Borrello, I.9
  • 189
    • 84910071057 scopus 로고    scopus 로고
    • Targeting immune suppression with PDE5 inhibition in end-stage multiple myeloma
    • Noonan KA, Ghosh N, Rudraraju L, Bui M, Borrello I. 2014. Targeting immune suppression with PDE5 inhibition in end-stage multiple myeloma. Cancer Immunol Res 2:725-731.
    • (2014) Cancer Immunol Res , vol.2 , pp. 725-731
    • Noonan, K.A.1    Ghosh, N.2    Rudraraju, L.3    Bui, M.4    Borrello, I.5
  • 192
    • 36348989162 scopus 로고    scopus 로고
    • Mechanism of all-trans retinoic acid effect on tumor-associated myeloid-derived suppressor cells
    • Nefedova Y, Fishman M, Sherman S, Wang X, Beg AA, Gabrilovich DI. 2007. Mechanism of all-trans retinoic acid effect on tumor-associated myeloid-derived suppressor cells. Cancer Res 67:11021-11028.
    • (2007) Cancer Res , vol.67 , pp. 11021-11028
    • Nefedova, Y.1    Fishman, M.2    Sherman, S.3    Wang, X.4    Beg, A.A.5    Gabrilovich, D.I.6
  • 199
    • 72849116796 scopus 로고    scopus 로고
    • Anti-tumour effects of bisphosphonates-what have we learned from in vivo models?
    • Brown HK, Holen I. 2009. Anti-tumour effects of bisphosphonates-what have we learned from in vivo models? Curr Cancer Drug Targets 9:807-823.
    • (2009) Curr Cancer Drug Targets , vol.9 , pp. 807-823
    • Brown, H.K.1    Holen, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.