메뉴 건너뛰기




Volumn 63, Issue 11, 2014, Pages 1769-1781

Targeted depletion of an MDSC subset unmasks pancreatic ductal adenocarcinoma to adaptive immunity

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

EID: 84894098516     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2013-306271     Document Type: Article
Times cited : (271)

References (55)
  • 2
    • 33751207530 scopus 로고    scopus 로고
    • Tumors of the pancreas
    • Hruban RH, Pitman MB, Klimstra DS, eds., Armed Forces Institute of Pathology
    • Hruban R. Tumors of the pancreas. In: Hruban RH, Pitman MB, Klimstra DS, eds. Atlas of tumor pathology. Armed Forces Institute of Pathology, 2007:111-64.
    • (2007) Atlas of Tumor Pathology. , pp. 111-164
    • Hruban, R.1
  • 3
    • 67149143399 scopus 로고    scopus 로고
    • Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
    • Olive KP, Jacobetz MA, Davidson CJ, et al. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 2009;324:1457-61.
    • (2009) Science , vol.324 , pp. 1457-1461
    • Olive, K.P.1    Jacobetz, M.A.2    Davidson, C.J.3
  • 4
    • 84858602107 scopus 로고    scopus 로고
    • Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma
    • Provenzano PP, Cuevas C, Chang AE, et al. Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma. Cancer Cell 2012;21:418-29.
    • (2012) Cancer Cell , vol.21 , pp. 418-429
    • Provenzano, P.P.1    Cuevas, C.2    Chang, A.E.3
  • 5
    • 84871157346 scopus 로고    scopus 로고
    • Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
    • Jacobetz MA, Chan DS, Neesse A, et al. Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer. Gut 2013;62:112-20.
    • (2013) Gut , vol.62 , pp. 112-120
    • Jacobetz, M.A.1    Chan, D.S.2    Neesse, A.3
  • 6
    • 35148814410 scopus 로고    scopus 로고
    • Dynamics of the immune reaction to pancreatic cancer from inception to invasion
    • Clark CE, Hingorani SR, Mick R, et al. Dynamics of the immune reaction to pancreatic cancer from inception to invasion. Cancer Res 2007;67:9518-27.
    • (2007) Cancer Res , vol.67 , pp. 9518-9527
    • Clark, C.E.1    Hingorani, S.R.2    Mick, R.3
  • 7
    • 78049380554 scopus 로고    scopus 로고
    • The patterns and dynamics of genomic instability in metastatic pancreatic cancer
    • Campbell PJ, Yachida S, Mudie LJ, et al. The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Nature 2010;467:1109-13.
    • (2010) Nature , vol.467 , pp. 1109-1113
    • Campbell, P.J.1    Yachida, S.2    Mudie, L.J.3
  • 8
    • 84869091997 scopus 로고    scopus 로고
    • Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
    • Biankin AV, Waddell N, Kassahn KS, et al. Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature 2012;491:399-405.
    • (2012) Nature , vol.491 , pp. 399-405
    • Biankin, A.V.1    Waddell, N.2    Kassahn, K.S.3
  • 10
    • 84877982642 scopus 로고    scopus 로고
    • Comprehensive genomic characterization of cutaneous malignant melanoma cell lines derived from metastatic lesions by whole-exome sequencing and SNP array profiling
    • Cifola I, Pietrelli A, Consolandi C, et al. Comprehensive genomic characterization of cutaneous malignant melanoma cell lines derived from metastatic lesions by whole-exome sequencing and SNP array profiling. PLoS ONE 2013;8:e63597.
    • (2013) PLoS ONE , vol.8 , pp. e63597
    • Cifola, I.1    Pietrelli, A.2    Consolandi, C.3
  • 11
    • 84866434919 scopus 로고    scopus 로고
    • Genomic landscape of non-small cell lung cancer in smokers and never-smokers
    • Govindan R, Ding L, Griffith M, et al. Genomic landscape of non-small cell lung cancer in smokers and never-smokers. Cell 2012;150:1121-34.
    • (2012) Cell , vol.150 , pp. 1121-1134
    • Govindan, R.1    Ding, L.2    Griffith, M.3
  • 12
    • 81255138488 scopus 로고    scopus 로고
    • Ipilimumab: An anti-CTLA-4 antibody for metastatic melanoma
    • Lipson EJ, Drake CG. Ipilimumab: an anti-CTLA-4 antibody for metastatic melanoma. Clin Cancer Res 2011;17:6958-62.
    • (2011) Clin Cancer Res , vol.17 , pp. 6958-6962
    • Lipson, E.J.1    Drake, C.G.2
  • 13
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity and immune correlates of anti-PD-1 antibody in cancer
    • Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012;366:2443-54.
    • (2012) N Engl J Med , vol.366 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 14
    • 77958050577 scopus 로고    scopus 로고
    • Phase 2 trial of single agent Ipilimumab (anti-CTLA-4) for locally advanced or metastatic pancreatic adenocarcinoma
    • Royal RE, Levy C, Turner K, et al. Phase 2 trial of single agent Ipilimumab (anti-CTLA-4) for locally advanced or metastatic pancreatic adenocarcinoma. J Immunother 2010;33:828-33.
    • (2010) J Immunother , vol.33 , pp. 828-833
    • Royal, R.E.1    Levy, C.2    Turner, K.3
  • 15
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • Brahmer JR, Tykodi SS, Chow LQ, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 2012;366:2455-65.
    • (2012) N Engl J Med , vol.366 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.3
  • 16
    • 84858687882 scopus 로고    scopus 로고
    • Novel agents in early phase clinical studies on refractory pancreatic cancer
    • Strimpakos AS, Syrigos KN, Saif MW. Novel agents in early phase clinical studies on refractory pancreatic cancer. JOP 2012;13:166-8.
    • (2012) JOP , vol.13 , pp. 166-168
    • Strimpakos, A.S.1    Syrigos, K.N.2    Saif, M.W.3
  • 17
    • 84862147254 scopus 로고    scopus 로고
    • Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia
    • Pylayeva-Gupta Y, Lee KE, Hajdu CH, et al. Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia. Cancer Cell 2012;21:836-47.
    • (2012) Cancer Cell , vol.21 , pp. 836-847
    • Pylayeva-Gupta, Y.1    Lee, K.E.2    Hajdu, C.H.3
  • 18
    • 84862150896 scopus 로고    scopus 로고
    • Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer
    • Bayne LJ, Beatty GL, Jhala N, et al. Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer. Cancer Cell 2012;21:822-35.
    • (2012) Cancer Cell , vol.21 , pp. 822-835
    • Bayne, L.J.1    Beatty, G.L.2    Jhala, N.3
  • 19
    • 55949116639 scopus 로고    scopus 로고
    • Human inhibitory receptor immunoglobulin-like transcript 2 amplifies CD11b+Gr1+ myeloid-derived suppressor cells that promote long-term survival of allografts
    • Zhang W, Liang S, Wu J, et al. Human inhibitory receptor immunoglobulin-like transcript 2 amplifies CD11b+Gr1+ myeloid-derived suppressor cells that promote long-term survival of allografts. Transplantation 2008;86:1125-34.
    • (2008) Transplantation , vol.86 , pp. 1125-1134
    • Zhang, W.1    Liang, S.2    Wu, J.3
  • 20
    • 80051777041 scopus 로고    scopus 로고
    • In vivo induction of myeloid suppressor cells and CD4(+)Foxp3(+) T regulatory cells prolongs skin allograft survival in mice
    • Adeegbe D, Serafini P, Bronte V, et al. In vivo induction of myeloid suppressor cells and CD4(+)Foxp3(+) T regulatory cells prolongs skin allograft survival in mice. Cell Transplantation 2011;20:941-54.
    • (2011) Cell Transplantation , vol.20 , pp. 941-954
    • Adeegbe, D.1    Serafini, P.2    Bronte, V.3
  • 21
    • 79952211990 scopus 로고    scopus 로고
    • Hepatic stellate cells regulate immune response by way of induction of myeloid suppressor cells in mice
    • Chou HS, Hsieh CC, Yang HR, et al. Hepatic stellate cells regulate immune response by way of induction of myeloid suppressor cells in mice. Hepatology 2011;53:1007-19.
    • (2011) Hepatology , vol.53 , pp. 1007-1019
    • Chou, H.S.1    Hsieh, C.C.2    Yang, H.R.3
  • 22
    • 84859727200 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells participate in preventing graft rejection
    • Wang Y, Gu X, Xiang J, et al. Myeloid-derived suppressor cells participate in preventing graft rejection. Clin Dev Immunol 2012;2012:731486.
    • (2012) Clin Dev Immunol 2012 , pp. 731486
    • Wang, Y.1    Gu, X.2    Xiang, J.3
  • 23
    • 9144266295 scopus 로고    scopus 로고
    • Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
    • Hingorani SR, Petricoin EF, Maitra A, et al. Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell 2003;4:437-50.
    • (2003) Cancer Cell , vol.4 , pp. 437-450
    • Hingorani, S.R.1    Petricoin, E.F.2    Maitra, A.3
  • 24
    • 19344362405 scopus 로고    scopus 로고
    • Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
    • Hingorani SR, Wang L, Multani AS, et al. Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell 2005;7:469-83.
    • (2005) Cancer Cell , vol.7 , pp. 469-483
    • Hingorani, S.R.1    Wang, L.2    Multani, A.S.3
  • 25
  • 26
    • 0027272534 scopus 로고
    • Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family
    • Fleming TJ, Fleming ML, Malek TR. Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family. J Immunol 1993;151:2399-408.
    • (1993) J Immunol , vol.151 , pp. 2399-2408
    • Fleming, T.J.1    Fleming, M.L.2    Malek, T.R.3
  • 27
    • 0037963473 scopus 로고    scopus 로고
    • Blood monocytes consist of two principal subsets with distinct migratory properties
    • Geissmann F, Jung S, Littman DR. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 2003;19:71-82.
    • (2003) Immunity , vol.19 , pp. 71-82
    • Geissmann, F.1    Jung, S.2    Littman, D.R.3
  • 28
    • 0035887505 scopus 로고    scopus 로고
    • CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells
    • Nakano H, Yanagita M, Gunn MD. CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells. J Exp Med 2001;194:1171-8.
    • (2001) J Exp Med , Issue.194 , pp. 1171-1178
    • Nakano, H.1    Yanagita, M.2    Gunn, M.D.3
  • 29
    • 4344697150 scopus 로고    scopus 로고
    • Identification and characterization of pDC-like cells in normal mouse skin and melanomas treated with imiquimod
    • Palamara F, Meindl S, Holcmann M, et al. Identification and characterization of pDC-like cells in normal mouse skin and melanomas treated with imiquimod. J Immunol 2004;173:3051-61.
    • (2004) J Immunol , vol.173 , pp. 3051-3061
    • Palamara, F.1    Meindl, S.2    Holcmann, M.3
  • 30
    • 0242333943 scopus 로고    scopus 로고
    • Successful elimination of memory-type CD8+ T cell subsets by the administration of anti-Gr-1 monoclonal antibody in vivo
    • Matsuzaki J, Tsuji T, Chamoto K, et al. Successful elimination of memory-type CD8+ T cell subsets by the administration of anti-Gr-1 monoclonal antibody in vivo. Cell Immunol 2003;224:98-105.
    • (2003) Cell Immunol , vol.224 , pp. 98-105
    • Matsuzaki, J.1    Tsuji, T.2    Chamoto, K.3
  • 31
    • 77951258918 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cell heterogeneity and subset definition
    • Peranzoni E, Zilio S, Marigo I, et al. Myeloid-derived suppressor cell heterogeneity and subset definition. Curr Opin Immunol 2010;22:238-44.
    • (2010) Curr Opin Immunol , vol.22 , pp. 238-244
    • Peranzoni, E.1    Zilio, S.2    Marigo, I.3
  • 32
    • 25644441744 scopus 로고    scopus 로고
    • Macrophages in the murine pancreas and their involvement in fetal endocrine development in vitro
    • Geutskens SB, Otonkoski T, Pulkkinen MA, et al. Macrophages in the murine pancreas and their involvement in fetal endocrine development in vitro. J Leukoc Biol 2005;78:845-52.
    • (2005) J Leukoc Biol , vol.78 , pp. 845-852
    • Geutskens, S.B.1    Otonkoski, T.2    Pulkkinen, M.A.3
  • 33
    • 84863116466 scopus 로고    scopus 로고
    • Transcriptomic analysis comparing tumor-associated neutrophils with granulocytic myeloid-derived suppressor cells and normal neutrophils
    • Fridlender ZG, Sun J, Mishalian I, et al. Transcriptomic analysis comparing tumor-associated neutrophils with granulocytic myeloid-derived suppressor cells and normal neutrophils. PLoS ONE 2012;7:e31524.
    • (2012) PLoS ONE , vol.7 , pp. e31524
    • Fridlender, Z.G.1    Sun, J.2    Mishalian, I.3
  • 34
    • 0242514648 scopus 로고    scopus 로고
    • Murine leukocytes with ring-shaped nuclei include granulocytes, monocytes and their precursors
    • Biermann H, Pietz B, Dreier R, et al. Murine leukocytes with ring-shaped nuclei include granulocytes, monocytes and their precursors. J Leukoc Biol 1999;65:217-31.
    • (1999) J Leukoc Biol , vol.65 , pp. 217-231
    • Biermann, H.1    Pietz, B.2    Dreier, R.3
  • 35
    • 46249090513 scopus 로고    scopus 로고
    • Colony-stimulating factors in inflammation and autoimmunity
    • Hamilton JA. Colony-stimulating factors in inflammation and autoimmunity. Nat Rev Immunol 2008;8:533-44.
    • (2008) Nat Rev Immunol , vol.8 , pp. 533-544
    • Hamilton, J.A.1
  • 36
    • 38149005534 scopus 로고    scopus 로고
    • Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice
    • Daley JM, Thomay AA, Connolly MD, et al. Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice. J Leukoc Biol 2008;83:64-70.
    • (2008) J Leukoc Biol , vol.83 , pp. 64-70
    • Daley, J.M.1    Thomay, A.A.2    Connolly, M.D.3
  • 37
    • 73249125588 scopus 로고    scopus 로고
    • Gr-1 antibody induces STAT signaling, macrophage marker expression and abrogation of myeloid-derived suppressor cell activity in BM cells
    • Ribechini E, Leenen PJ, Lutz MB. Gr-1 antibody induces STAT signaling, macrophage marker expression and abrogation of myeloid-derived suppressor cell activity in BM cells. Eur J Immunol 2009;39:3538-51.
    • (2009) Eur J Immunol , vol.39 , pp. 3538-3551
    • Ribechini, E.1    Leenen, P.J.2    Lutz, M.B.3
  • 38
    • 73149092567 scopus 로고    scopus 로고
    • Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
    • Wolchok JD, Hoos A, O'Day S, et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res 2009;15:7412-20.
    • (2009) Clin Cancer Res , vol.15 , pp. 7412-7420
    • Wolchok, J.D.1    Hoos, A.2    O'day, S.3
  • 40
    • 0031563901 scopus 로고    scopus 로고
    • Temporal dynamics of CD69 expression on lymphoid cells
    • Craston R, Koh M, Mc Dermott A, et al. Temporal dynamics of CD69 expression on lymphoid cells. J Immunol Methods 1997;209:37-45.
    • (1997) J Immunol Methods , vol.209 , pp. 37-45
    • Craston, R.1    Koh, M.2    Mc Dermott, A.3
  • 41
  • 42
    • 78651451436 scopus 로고    scopus 로고
    • Endogenous T cell responses to antigens expressed in lung adenocarcinomas delay malignant tumor progression
    • DuPage M, Cheung AF, Mazumdar C, et al. Endogenous T cell responses to antigens expressed in lung adenocarcinomas delay malignant tumor progression. Cancer Cell 2011;19:72-85.
    • (2011) Cancer Cell , vol.19 , pp. 72-85
    • Dupage, M.1    Cheung, A.F.2    Mazumdar, C.3
  • 43
    • 24344436369 scopus 로고    scopus 로고
    • Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance
    • Willimsky G, Blankenstein T. Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance. Nature 2005;437:141-6.
    • (2005) Nature , vol.437 , pp. 141-146
    • Willimsky, G.1    Blankenstein, T.2
  • 44
    • 84866557942 scopus 로고    scopus 로고
    • Causes, consequences and remedies for growth-induced solid stress in murine and human tumors
    • Stylianopoulos T, Martin JD, Chauhan VP, et al. Causes, consequences and remedies for growth-induced solid stress in murine and human tumors. Proc Natl Acad Sci USA 2012;109:15101-8.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 15101-15108
    • Stylianopoulos, T.1    Martin, J.D.2    Chauhan, V.P.3
  • 45
    • 34248141223 scopus 로고    scopus 로고
    • Tumor-stroma interactions in pancreatic ductal adenocarcinoma
    • Mahadevan D, Von Hoff DD. Tumor-stroma interactions in pancreatic ductal adenocarcinoma. Mol Cancer Ther 2007;6:1186-97.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1186-1197
    • Mahadevan, D.1    Von Hoff, D.D.2
  • 46
    • 54849440346 scopus 로고    scopus 로고
    • Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden and doxorubicin-cyclophosphamide chemotherapy
    • Diaz-Montero CM, Salem ML, Nishimura MI, et al. Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol Immunother 2009;58:49-59.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 49-59
    • Diaz-Montero, C.M.1    Salem, M.L.2    Nishimura, M.I.3
  • 47
    • 84856899903 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells in cancer patients: A clinical perspective
    • Montero AJ, Diaz-Montero CM, Kyriakopoulos CE, et al. Myeloid-derived suppressor cells in cancer patients: a clinical perspective. J Immunother 2012;35:107-15.
    • (2012) J Immunother , vol.35 , pp. 107-115
    • Montero, A.J.1    Diaz-Montero, C.M.2    Kyriakopoulos, C.E.3
  • 48
    • 84866537713 scopus 로고    scopus 로고
    • Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth
    • Porembka MR, Mitchem JB, Belt BA, et al. Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth. Cancer Immunol Immunother 2012;61:1373-85.
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 1373-1385
    • Porembka, M.R.1    Mitchem, J.B.2    Belt, B.A.3
  • 49
    • 79951823584 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties
    • Brandau S, Trellakis S, Bruderek K, et al. Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties. J Leukoc Biol 2011;89:311-17.
    • (2011) J Leukoc Biol , vol.89 , pp. 311-317
    • Brandau, S.1    Trellakis, S.2    Bruderek, K.3
  • 50
  • 51
    • 79959966013 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: General characteristics and relevance to clinical management of pancreatic cancer
    • Goedegebuure P, Mitchem JB, Porembka MR, et al. Myeloid-derived suppressor cells: general characteristics and relevance to clinical management of pancreatic cancer. Curr Cancer Drug Targets 2011;11:734-51.
    • (2011) Curr Cancer Drug Targets , vol.11 , pp. 734-751
    • Goedegebuure, P.1    Mitchem, J.B.2    Porembka, M.R.3
  • 52
    • 84879850236 scopus 로고    scopus 로고
    • Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: A role for targeting the CCL2/CC R2 axis
    • Sanford DE, Belt BA, Panni RZ, et al. Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: a role for targeting the CCL2/CC R2 axis. Clin Cancer Res 2013;19:3404-15.
    • (2013) Clin Cancer Res , vol.19 , pp. 3404-3415
    • Sanford, D.E.1    Belt, B.A.2    Panni, R.Z.3
  • 54
    • 84877825407 scopus 로고    scopus 로고
    • Therapeutic regulation of myeloid-derived suppressor cells and immune response to cancer vaccine in patients with extensive stage small cell lung cancer
    • Iclozan C, Antonia S, Chiappori A, et al. Therapeutic regulation of myeloid-derived suppressor cells and immune response to cancer vaccine in patients with extensive stage small cell lung cancer. Cancer Immunol Immunother 2013;62:909-18.
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 909-918
    • Iclozan, C.1    Antonia, S.2    Chiappori, A.3
  • 55
    • 84860445233 scopus 로고    scopus 로고
    • Hematopoietic growth factors: Personalization of risks and benefits
    • Puhalla S, Bhattacharya S, Davidson NE. Hematopoietic growth factors: personalization of risks and benefits. Mol Oncol 2012;6:237-41.
    • (2012) Mol Oncol , vol.6 , pp. 237-241
    • Puhalla, S.1    Bhattacharya, S.2    Davidson, N.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.