메뉴 건너뛰기




Volumn 18, Issue 3, 2003, Pages 194-202

Expression and Functional Characterization of Human ABC Transporter ABCG2 Variants in Insect Cells

Author keywords

ABC transporter; ABCG2; BCRP; pharmacogenomics; single nucleotide polymorphism

Indexed keywords


EID: 85009628144     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.18.194     Document Type: Article
Times cited : (27)

References (39)
  • 3
    • 0030738677 scopus 로고    scopus 로고
    • Multidrug resistance: molecular mechanisms and clinical relevance
    • Ling, V.: Multidrug resistance: molecular mechanisms and clinical relevance. Cancer Chemother. Pharmacol., 40: S3-S8 (1997).
    • (1997) Cancer Chemother. Pharmacol. , vol.40 , pp. S3-S8
    • Ling, V.1
  • 6
    • 0034917716 scopus 로고    scopus 로고
    • The human ATP-binding cassette (ABC) transporter superfamily
    • Dean, M., Rzhetsky, A. and Allikmets, R.: The human ATP-binding cassette (ABC) transporter superfamily. Genome Res., 11: 1156-1166 (2001).
    • (2001) Genome Res. , vol.11 , pp. 1156-1166
    • Dean, M.1    Rzhetsky, A.2    Allikmets, R.3
  • 7
    • 0036074018 scopus 로고    scopus 로고
    • Mammalian ABC transporters in health and disease
    • Borst, P. and Oude Elferink, R.: Mammalian ABC transporters in health and disease. Annu. Rev. Biochem., 71: 537-592 (2002).
    • (2002) Annu. Rev. Biochem. , vol.71 , pp. 537-592
    • Borst, P.1    Oude Elferink, R.2
  • 10
    • 0032404092 scopus 로고    scopus 로고
    • A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance
    • Allikmets, R., Schriml, L. M., Hutchinson, A., Romano-Spica, V. and Dean, M.: A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. Cancer Res., 58: 5337-5339 (1998).
    • (1998) Cancer Res. , vol.58 , pp. 5337-5339
    • Allikmets, R.1    Schriml, L.M.2    Hutchinson, A.3    Romano-Spica, V.4    Dean, M.5
  • 12
    • 0032535004 scopus 로고    scopus 로고
    • Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C
    • Rabindran, S. K., He, H., Singh, M., Brown, E., Collins, K. I., Annable, T. and Greenberger, L. M.: Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C. Cancer Res., 58: 5850-5858 (1998).
    • (1998) Cancer Res. , vol.58 , pp. 5850-5858
    • Rabindran, S.K.1    He, H.2    Singh, M.3    Brown, E.4    Collins, K.I.5    Annable, T.6    Greenberger, L.M.7
  • 16
    • 0033429542 scopus 로고    scopus 로고
    • Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells
    • Brangi, M., Litman, T., Ciotti, M., Nishiyama, K., Kohlhagen, G., Takimoto, C., Robey, R., Pommier, Y., Fojo, T. and Bates, S. E.: Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells. Cancer Res., 59: 5938-5946 (1999).
    • (1999) Cancer Res. , vol.59 , pp. 5938-5946
    • Brangi, M.1    Litman, T.2    Ciotti, M.3    Nishiyama, K.4    Kohlhagen, G.5    Takimoto, C.6    Robey, R.7    Pommier, Y.8    Fojo, T.9    Bates, S.E.10
  • 17
    • 0034081847 scopus 로고    scopus 로고
    • The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)
    • Litman, T., Brangi, M., Hudson, E., Fetsch, P., Abati, A., Ross, D. D., Miyake, K., Resau, J. H. and Bates, S. E.: The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2). J. Cell Sci., 113: 2011-2021 (2000).
    • (2000) J. Cell Sci. , vol.113 , pp. 2011-2021
    • Litman, T.1    Brangi, M.2    Hudson, E.3    Fetsch, P.4    Abati, A.5    Ross, D.D.6    Miyake, K.7    Resau, J.H.8    Bates, S.E.9
  • 22
    • 0037073730 scopus 로고    scopus 로고
    • Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter
    • Özvegy, C., Varadi, A. and Sarkadi, B.: Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. J. Biol. Chem., 277: 47980-47990 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 47980-47990
    • Özvegy, C.1    Varadi, A.2    Sarkadi, B.3
  • 23
    • 0036732010 scopus 로고    scopus 로고
    • Overexpression of wild-type breast cancer resistance protein mediates methotrexate resistance
    • Volk, E. L., Farley, K. M., Wu, Y., Li, F., Robey, R. W. and Schneider, E.: Overexpression of wild-type breast cancer resistance protein mediates methotrexate resistance. Cancer Res., 62: 5035-5040 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 5035-5040
    • Volk, E.L.1    Farley, K.M.2    Wu, Y.3    Li, F.4    Robey, R.W.5    Schneider, E.6
  • 26
    • 0020681165 scopus 로고
    • Inorganic phosphate assay with malachite green: an improvement and evaluation
    • Carter, S. G. and Karl, D. W.: Inorganic phosphate assay with malachite green: an improvement and evaluation. J. Biochem. Biophys. Methods, 7: 7-13 (1982).
    • (1982) J. Biochem. Biophys. Methods , vol.7 , pp. 7-13
    • Carter, S.G.1    Karl, D.W.2
  • 27
    • 0026722467 scopus 로고
    • Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase
    • Sarkadi, B., Price, E. M., Boucher, R. C., Germann, U. A. and Scarborough, G. A.: Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase. J. Biol. Chem., 267: 4854-4858 (1992).
    • (1992) J. Biol. Chem. , vol.267 , pp. 4854-4858
    • Sarkadi, B.1    Price, E.M.2    Boucher, R.C.3    Germann, U.A.4    Scarborough, G.A.5
  • 28
    • 0024472768 scopus 로고
    • ATP/Mg2+-dependent cardiac transport system for glutathione S-conjugates: A study using rat heart sarcolemma vesicles
    • Ishikawa, T.: ATP/Mg2+-dependent cardiac transport system for glutathione S-conjugates: A study using rat heart sarcolemma vesicles. J. Biol. Chem., 264: 17343-17348 (1989).
    • (1989) J. Biol. Chem. , vol.264 , pp. 17343-17348
    • Ishikawa, T.1
  • 30
    • 0037050736 scopus 로고    scopus 로고
    • Dominant-negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S-S dependent homodimerization.
    • Kage, K., Tsukahara, S., Sugiyama, T., Asada, S., Ishikawa, E., Tsuruo, T. and Sugimoto, Y.: Dominant-negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S-S dependent homodimerization. Int. J. Cancer, 97: 626-630 (2002).
    • (2002) Int. J. Cancer , vol.97 , pp. 626-630
    • Kage, K.1    Tsukahara, S.2    Sugiyama, T.3    Asada, S.4    Ishikawa, E.5    Tsuruo, T.6    Sugimoto, Y.7
  • 31
    • 0035300476 scopus 로고    scopus 로고
    • Identification of breast cancer resistant protein/mitoxantrone resistance/placenta-specific, ATP-binding cassette transporter as a transporter of NB-506 and J-107088, topoisomerase I inhibitors with an indolocarbazole structure
    • Komatani, H., Kotani, H., Hara, Y., Nakagawa, R., Matsumoto, M., Arakawa, H. and Nishimura, S.: Identification of breast cancer resistant protein/mitoxantrone resistance/placenta-specific, ATP-binding cassette transporter as a transporter of NB-506 and J-107088, topoisomerase I inhibitors with an indolocarbazole structure. Cancer Res., 61: 2827-2832 (2001).
    • (2001) Cancer Res. , vol.61 , pp. 2827-2832
    • Komatani, H.1    Kotani, H.2    Hara, Y.3    Nakagawa, R.4    Matsumoto, M.5    Arakawa, H.6    Nishimura, S.7
  • 32
    • 0026741788 scopus 로고
    • Energy-dependent efflux of methotrexate in L1210 leukemia cells: Evidence for the role of an ATPase obtained with inside-out plasma membrane vesicles
    • Schlemmer, S. R. and Sirotnak, F. M.: Energy-dependent efflux of methotrexate in L1210 leukemia cells: Evidence for the role of an ATPase obtained with inside-out plasma membrane vesicles. J. Biol. Chem., 267: 14746-14752 (1992).
    • (1992) J. Biol. Chem. , vol.267 , pp. 14746-14752
    • Schlemmer, S.R.1    Sirotnak, F.M.2
  • 33
    • 0030580806 scopus 로고    scopus 로고
    • Identification of efflux systems for large anions and anionic conjugates as the mediators of methotrexate efflux in L1210 cells
    • Saxena, M. and Henderson, G. B.: Identification of efflux systems for large anions and anionic conjugates as the mediators of methotrexate efflux in L1210 cells. Biochem. Pharmacol., 51: 974-982 (1996).
    • (1996) Biochem. Pharmacol. , vol.51 , pp. 974-982
    • Saxena, M.1    Henderson, G.B.2
  • 36
    • 0036606023 scopus 로고    scopus 로고
    • Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system
    • Chen, Z.-S., Lee, K., Walther, S., Raftogianis, R. B., Kuwano, M., Zeng, H. and Kruh, G. D.: Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system. Cancer Res., 62: 3144-3150 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 3144-3150
    • Chen, Z.-S.1    Lee, K.2    Walther, S.3    Raftogianis, R.B.4    Kuwano, M.5    Zeng, H.6    Kruh, G.D.7
  • 37
    • 0042068263 scopus 로고    scopus 로고
    • A functional study on the polymorphism of ATP-binding cassette transporter ABCG2: critical role of Arg482 in methotrexate transport
    • in press
    • Mitomo, H., Kato, R., Ito, A., Kasamatsu, S., Ikegami, Y., Kii, I., Kudo, A., Kobatake, E., Sumino, Y. and Ishikawa, T.: A functional study on the polymorphism of ATP-binding cassette transporter ABCG2: critical role of Arg482 in methotrexate transport. Biochem. J., 373: in press (2003).
    • (2003) Biochem. J. , vol.373
    • Mitomo, H.1    Kato, R.2    Ito, A.3    Kasamatsu, S.4    Ikegami, Y.5    Kii, I.6    Kudo, A.7    Kobatake, E.8    Sumino, Y.9    Ishikawa, T.10
  • 38
    • 0037089528 scopus 로고    scopus 로고
    • A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for doxorubicin resistance
    • Allen, J. D., Jackson, S. C. and Schinkel, A. H.: A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for doxorubicin resistance. Cancer Res., 62: 2294-2299 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 2294-2299
    • Allen, J.D.1    Jackson, S.C.2    Schinkel, A.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.