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Volumn 51, Issue 7, 1996, Pages 975-982

Identification of efflux systems for large anions and anionic conjugates as the mediators of methotrexate efflux in L1210 cells

Author keywords

anion efflux; bilirubin ditaurate; biphenylacetic acid; dinitrophenyl S glutathione; ethacrynic acid; glutathione conjugate efflux; inside out vesicles; methotrexate; methotrexate efflux

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; ADENOSINE TRIPHOSPHATE; BROMSULFOPHTHALEIN; ETACRYNIC ACID; FELBINAC; FLURBIPROFEN; GLUTATHIONE; INDOPROFEN; METHOTREXATE; RADIOISOTOPE; ANION;

EID: 0030580806     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00051-2     Document Type: Article
Times cited : (30)

References (42)
  • 1
    • 0024329881 scopus 로고
    • The biochemistry of P-glycoproteinmediaced multidrug resistance
    • Endicott JA and Ling V, The biochemistry of P-glycoproteinmediaced multidrug resistance. Annu Rev Biochem 58: 137-141, 1989.
    • (1989) Annu Rev Biochem , vol.58 , pp. 137-141
    • Endicott, J.A.1    Ling, V.2
  • 2
    • 0026459859 scopus 로고
    • The ATP-dependent glutathione S-conjugate export pump
    • Ishikawa T, The ATP-dependent glutathione S-conjugate export pump. Trends Biochem Sci 17: 463-468, 1992.
    • (1992) Trends Biochem Sci , vol.17 , pp. 463-468
    • Ishikawa, T.1
  • 3
    • 0027457145 scopus 로고
    • ATP-dependent transport systems for organic anions
    • Zimniak P and Awasthi YC, ATP-dependent transport systems for organic anions. Hepatology 17: 330-339, 1993.
    • (1993) Hepatology , vol.17 , pp. 330-339
    • Zimniak, P.1    Awasthi, Y.C.2
  • 4
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman M and Pastan I, Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 62: 385-427, 1993.
    • (1993) Annu Rev Biochem , vol.62 , pp. 385-427
    • Gottesman, M.1    Pastan, I.2
  • 5
    • 0026621245 scopus 로고
    • ABC transporters: From microorganisms to man
    • Higgins CF, ABC transporters: From microorganisms to man. Annu Rev Cell Biol 8: 67-113, 1992.
    • (1992) Annu Rev Cell Biol , vol.8 , pp. 67-113
    • Higgins, C.F.1
  • 6
    • 0024472768 scopus 로고
    • 2+-dependent cardiac transport system for glutathione S-conjugates: A study using rat heart sarcolemma vesicles
    • 2+-dependent cardiac transport system for glutathione S-conjugates: A study using rat heart sarcolemma vesicles. J Biol Chem 264: 17343-17348, 1989.
    • (1989) J Biol Chem , vol.264 , pp. 17343-17348
    • Ishikawa, T.1
  • 7
    • 0025343017 scopus 로고
    • Mechanisms of glutathione S-conjugate transport in canalicular and basolateral rat liver plasma membranes
    • Kobayashi K, Sogame Y, Hara H and Hayashi K, Mechanisms of glutathione S-conjugate transport in canalicular and basolateral rat liver plasma membranes. J Biol Chem 265: 7737-7741, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 7737-7741
    • Kobayashi, K.1    Sogame, Y.2    Hara, H.3    Hayashi, K.4
  • 8
    • 0027305406 scopus 로고
    • Glutathione-associated cis-diamminedichloroplannum(II) metabolism and ATP-dependent efflux from leukemia cells: Molecular characterization of glutathione-platinum complex and its biological significance
    • Ishikawa T and Ali-Osman F, Glutathione-associated cis-diamminedichloroplannum(II) metabolism and ATP-dependent efflux from leukemia cells: Molecular characterization of glutathione-platinum complex and its biological significance. J Biol Chem 268: 20116-20125, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 20116-20125
    • Ishikawa, T.1    Ali-Osman, F.2
  • 9
    • 0025861580 scopus 로고
    • ATP-dependent S-(2,4-dintrophenyl)glutathione transport in canalicular membrane vesicles from rat liver
    • Akerboom TPM, Narayanaswami V, Kunst M and Sies H, ATP-dependent S-(2,4-dintrophenyl)glutathione transport in canalicular membrane vesicles from rat liver. J Biol Chem 266: 13147-13152, 1991.
    • (1991) J Biol Chem , vol.266 , pp. 13147-13152
    • Akerboom, T.P.M.1    Narayanaswami, V.2    Kunst, M.3    Sies, H.4
  • 10
    • 0027116269 scopus 로고
    • m transport of dinitrophenyl glutathione in inside out vesicles from human erythrocytes
    • m transport of dinitrophenyl glutathione in inside out vesicles from human erythrocytes. Biochim Biophys Acta 1103: 115-119, 1992.
    • (1992) Biochim Biophys Acta , vol.1103 , pp. 115-119
    • Akerboom, T.P.M.1    Bartosz, G.2    Sies, H.3
  • 11
    • 0028939884 scopus 로고
    • ATP-dependent efflux of 2,4-dinitrophenyl-S-glutathione: Properties of two distinct transport systems in inside-out vesicles from L1210 cells and a variant subline with altered efflux of methotrexate and cholate
    • Saxena M and Henderson GB, ATP-dependent efflux of 2,4-dinitrophenyl-S-glutathione: Properties of two distinct transport systems in inside-out vesicles from L1210 cells and a variant subline with altered efflux of methotrexate and cholate. J Biol Chem 270: 5312-5319, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 5312-5319
    • Saxena, M.1    Henderson, G.B.2
  • 12
    • 0017809192 scopus 로고
    • Regulation of adenosine 3′:5′-monophosphate efflux from animal cells
    • Rindler MJ, Bashor MM, Spitzer N and Saier MH, Regulation of adenosine 3′:5′-monophosphate efflux from animal cells. J Biol Chem 253: 5431-5436, 1978.
    • (1978) J Biol Chem , vol.253 , pp. 5431-5436
    • Rindler, M.J.1    Bashor, M.M.2    Spitzer, N.3    Saier, M.H.4
  • 13
    • 0023848921 scopus 로고
    • FURA-2 secretion and sequestration in macrophages: A blocker of organic anion transport reveals that these processes occur via a membrane transport system for organic anions
    • Di Virgilio F, Steinberg TH, Swanson JA and Silverstein SC, FURA-2 secretion and sequestration in macrophages: A blocker of organic anion transport reveals that these processes occur via a membrane transport system for organic anions. J Immunol 140: 915-920, 1988.
    • (1988) J Immunol , vol.140 , pp. 915-920
    • Di Virgilio, F.1    Steinberg, T.H.2    Swanson, J.A.3    Silverstein, S.C.4
  • 14
    • 0025129308 scopus 로고
    • Identification of cholate as a shared substrate for the unidirectional efflux systems for methotrexate in L1210 cells
    • Henderson GB and Tsuji JM, Identification of cholate as a shared substrate for the unidirectional efflux systems for methotrexate in L1210 cells. Biochim Biophys Acta 1051: 60-70, 1990.
    • (1990) Biochim Biophys Acta , vol.1051 , pp. 60-70
    • Henderson, G.B.1    Tsuji, J.M.2
  • 15
    • 0026078482 scopus 로고
    • Evidence for cAMP and cholate extrusion in C6 rat glioma cells by a common anion efflux pump
    • Henderson GB and Strauss BP, Evidence for cAMP and cholate extrusion in C6 rat glioma cells by a common anion efflux pump. J Biol Chem 266: 1641-1645, 1991.
    • (1991) J Biol Chem , vol.266 , pp. 1641-1645
    • Henderson, G.B.1    Strauss, B.P.2
  • 17
    • 0025991571 scopus 로고
    • Rat liver canalicular membrane vesicles contain an ATP-dependent bile acid transport system
    • Nishida T, Gatmaitan Z, Che M and Arias IM, Rat liver canalicular membrane vesicles contain an ATP-dependent bile acid transport system. Proc Natl Acad Sci USA 88: 6590-6594, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 6590-6594
    • Nishida, T.1    Gatmaitan, Z.2    Che, M.3    Arias, I.M.4
  • 18
    • 0026490803 scopus 로고
    • Two distinct mechanisms for bilirubin glucuronide transport by rat bile canalicular membrane vesicles. Demonstration of defective ATP-dependent transport in rats (TR-) with inherited conjugated hyperbilirubinemia
    • Nishida T, Gatmaitan Z, Roy-Chowdhry J and Arias IM, Two distinct mechanisms for bilirubin glucuronide transport by rat bile canalicular membrane vesicles. Demonstration of defective ATP-dependent transport in rats (TR-) with inherited conjugated hyperbilirubinemia. J Clin Invest 90: 2130-2135, 1992.
    • (1992) J Clin Invest , vol.90 , pp. 2130-2135
    • Nishida, T.1    Gatmaitan, Z.2    Roy-Chowdhry, J.3    Arias, I.M.4
  • 20
    • 0027984511 scopus 로고
    • The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates
    • Leier I, Jedlitschky G, Buchholz U, Cole SPC, Deeley RG and Keppler D, The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates. J Biol Chem 269: 27807-27810, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 27807-27810
    • Leier, I.1    Jedlitschky, G.2    Buchholz, U.3    Cole, S.P.C.4    Deeley, R.G.5    Keppler, D.6
  • 22
    • 0028578004 scopus 로고
    • Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport
    • Muller M, Meijer C, Zaman GJR, Borst P, Scheper RJ, Mulder NH, de Vries EGE and Jansen PLM, Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport. Proc Natl Acad Sci USA 91: 13033-13037, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 13033-13037
    • Muller, M.1    Meijer, C.2    Zaman, G.J.R.3    Borst, P.4    Scheper, R.J.5    Mulder, N.H.6    De Vries, E.G.E.7    Jansen, P.L.M.8
  • 23
    • 0014690663 scopus 로고
    • Transport energetics of the folic acid analogue, methotrexate, in L1210 leukemia cells
    • Goldman ID, Transport energetics of the folic acid analogue, methotrexate, in L1210 leukemia cells. J Biol Chem 244: 3779-3785, 1969.
    • (1969) J Biol Chem , vol.244 , pp. 3779-3785
    • Goldman, I.D.1
  • 24
    • 0019423221 scopus 로고
    • Increased accumulation of methotrexate by murine tumor cells in vitro in the presence of probenecid which is mediated by a preferential inhibition of efflux
    • Sirotnak FM, Moccio DM and Young CW, Increased accumulation of methotrexate by murine tumor cells in vitro in the presence of probenecid which is mediated by a preferential inhibition of efflux. Cancer Res 41: 966-970, 1981.
    • (1981) Cancer Res , vol.41 , pp. 966-970
    • Sirotnak, F.M.1    Moccio, D.M.2    Young, C.W.3
  • 25
    • 0021983477 scopus 로고
    • Inhibitory effects of probenecid on the individual transport routes which mediate the influx and efflux of methotrexate in L1210 cells
    • Henderson GB and Zevely EM, Inhibitory effects of probenecid on the individual transport routes which mediate the influx and efflux of methotrexate in L1210 cells. Biochem Pharmacol 34: 1725-1729, 1985.
    • (1985) Biochem Pharmacol , vol.34 , pp. 1725-1729
    • Henderson, G.B.1    Zevely, E.M.2
  • 26
    • 0026761157 scopus 로고
    • Separation and inhibitor specificity of a second unidirectional efflux route for methotrexate in L1210 cells
    • Henderson GB, Separation and inhibitor specificity of a second unidirectional efflux route for methotrexate in L1210 cells. Biochim Biophys Acta 1110: 137-143, 1992.
    • (1992) Biochim Biophys Acta , vol.1110 , pp. 137-143
    • Henderson, G.B.1
  • 27
    • 0027378617 scopus 로고
    • Altered expression of unidirectional extrusion routes for methotrexate and cholate in an efflux variant of L1210 cells
    • Henderson GB and Hughes TR, Altered expression of unidirectional extrusion routes for methotrexate and cholate in an efflux variant of L1210 cells. Biochim Biophys Acta 1152: 91-98, 1993.
    • (1993) Biochim Biophys Acta , vol.1152 , pp. 91-98
    • Henderson, G.B.1    Hughes, T.R.2
  • 28
    • 0028242342 scopus 로고
    • Functional implications from the effects of 1-chloro-2,4-dinitrobenzene and ethacrynic acid on efflux routes for methotrexate and cholate in L1210 cells
    • Henderson GB, Hughes TR and Saxena M, Functional implications from the effects of 1-chloro-2,4-dinitrobenzene and ethacrynic acid on efflux routes for methotrexate and cholate in L1210 cells. J Biol Chem 269: 13382-13389, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 13382-13389
    • Henderson, G.B.1    Hughes, T.R.2    Saxena, M.3
  • 29
    • 0019814592 scopus 로고
    • Characterization of the methotrexate transport defect in a resistant L1210 lymphoma cell line
    • McCormick JI, Susten SS and Freisheim JH, Characterization of the methotrexate transport defect in a resistant L1210 lymphoma cell line. Arch Biochem Biophys 212: 311-318, 1981.
    • (1981) Arch Biochem Biophys , vol.212 , pp. 311-318
    • McCormick, J.I.1    Susten, S.S.2    Freisheim, J.H.3
  • 30
    • 0025275523 scopus 로고
    • Characteristics of a novel transport system for folate compounds in wild-type and methotrexate-resistant L1210 cells
    • Henderson GB and Strauss BP, Characteristics of a novel transport system for folate compounds in wild-type and methotrexate-resistant L1210 cells. Cancer Res 50: 1709-1714, 1990.
    • (1990) Cancer Res , vol.50 , pp. 1709-1714
    • Henderson, G.B.1    Strauss, B.P.2
  • 31
    • 0014221606 scopus 로고
    • Chemical coupling of proteins to agarose
    • Porath J, Axen R and Ernback S, Chemical coupling of proteins to agarose. Nature 215: 1491-1492, 1967.
    • (1967) Nature , vol.215 , pp. 1491-1492
    • Porath, J.1    Axen, R.2    Ernback, S.3
  • 32
    • 0026018768 scopus 로고
    • ATP-dependent leukotriene export from mastocytoma cells
    • Schaub T, Ishikawa T and Keppler D, ATP-dependent leukotriene export from mastocytoma cells. FEBS Lett 279: 83-86, 1991.
    • (1991) FEBS Lett , vol.279 , pp. 83-86
    • Schaub, T.1    Ishikawa, T.2    Keppler, D.3
  • 33
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 35
    • 0016360444 scopus 로고
    • Preparation of impermeable ghosts and inside-out vesicles from human erythrocyte membranes
    • Steck TL and Kant JA, Preparation of impermeable ghosts and inside-out vesicles from human erythrocyte membranes. Methods Enzymol 31A: 172-180, 1974.
    • (1974) Methods Enzymol , vol.31 A , pp. 172-180
    • Steck, T.L.1    Kant, J.A.2
  • 36
    • 0015070989 scopus 로고
    • A model system for the study of heteroexchange diffusion: Methotrexate-folate interactions in L1210 leukemia and Ehrlich ascites tumor cells
    • Goldman ID, A model system for the study of heteroexchange diffusion: Methotrexate-folate interactions in L1210 leukemia and Ehrlich ascites tumor cells. Biochim Biophys Acta 233: 624-634, 1971.
    • (1971) Biochim Biophys Acta , vol.233 , pp. 624-634
    • Goldman, I.D.1
  • 37
    • 0000340505 scopus 로고
    • Transport of folate compounds into cells
    • (Eds. Bkkley RL and Whitehead M), John Wiley, New York
    • Henderson GB, Transport of folate compounds into cells. In: Nutritional, Pharmacological, and Physiological Aspects (Eds. Bkkley RL and Whitehead M), Vol. 3, pp. 207-250. John Wiley, New York, 1986.
    • (1986) Nutritional, Pharmacological, and Physiological Aspects , vol.3 , pp. 207-250
    • Henderson, G.B.1
  • 38
    • 0026741788 scopus 로고
    • Energy-dependent efflux of methotrexate in L1210 leukemia cells: Evidence for a role of an ATPase obtained with inside-out vesicles
    • Schlemmer SR and Sirotnak FM, Energy-dependent efflux of methotrexate in L1210 leukemia cells: Evidence for a role of an ATPase obtained with inside-out vesicles. J Biol Chem 267: 14746-14752, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 14746-14752
    • Schlemmer, S.R.1    Sirotnak, F.M.2
  • 39
    • 8044260030 scopus 로고
    • GS-X pump mediates ATP-dependent export of methotrexate
    • Mansur-Garza EM and Ishikawa T, GS-X pump mediates ATP-dependent export of methotrexate. Proc Am Assoc Cancer Res 35: 376, 1994.
    • (1994) Proc Am Assoc Cancer Res , vol.35 , pp. 376
    • Mansur-Garza, E.M.1    Ishikawa, T.2
  • 40
    • 0023734378 scopus 로고
    • Identification of the bromosulfophthalein-sensitive efflux route for methotrexate as the site of action of vincristine in the vincristine-dependent enhancement of methotrexate uptake in L1210 cells
    • Henderson GB and Tsuji JM, Identification of the bromosulfophthalein-sensitive efflux route for methotrexate as the site of action of vincristine in the vincristine-dependent enhancement of methotrexate uptake in L1210 cells. Cancer Res 48: 5995-6001, 1988.
    • (1988) Cancer Res , vol.48 , pp. 5995-6001
    • Henderson, G.B.1    Tsuji, J.M.2
  • 41
    • 0028889010 scopus 로고
    • Distinct systems mediate the unidirectional efflux of methotrexate and cholate in human CCRF-CEM cells
    • Henderson GB, Hughes TR and Saxena M, Distinct systems mediate the unidirectional efflux of methotrexate and cholate in human CCRF-CEM cells. Arch Biochem Biophys 316: 77-82, 1995.
    • (1995) Arch Biochem Biophys , vol.316 , pp. 77-82
    • Henderson, G.B.1    Hughes, T.R.2    Saxena, M.3


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