Single-Cell-Based Analysis Highlights a Surge in Cell-to-Cell Molecular Variability Preceding Irreversible Commitment in a Differentiation Process

PLoS Biology

Volumn 14, Issue 12, 2016, Pages

  Richard, Angélique ^a   Boullu, Loïs ^b,c,d   Herbach, Ulysse ^a,b,c   Bonnafoux, Arnaud ^a,b,e   Morin, Valérie ^f   Vallin, Elodie ^a   Guillemin, Anissa ^a   Papili Gao, Nan ^g,h   Gunawan, Rudiyanto ^g,h   Cosette, Jérémie ⁱ   Arnaud, Ophélie ^j   Kupiec, Jean Jacques ^k   Espinasse, Thibault ^c   Gonin Giraud, Sandrine ^a   Gandrillon, Olivier ^a,b  

^a UNIVERSITÉ DE LYON   (France)

^b Inria Center Grenoble Rhône Alpes   (France)

^c UNIVERSITÉ LYON 1   (France)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

^e The CoSMo company   (France)

^f UNIVERSITÉ LYON 1   (France)

^g ETH ZURICH   (Switzerland)

^h SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

ⁱ UNIVERSITÉ D EVRY VAL D ESSONNE   (France)

^j RIKEN   (Japan)

^k INSERM   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL POPULATION; CELL SIZE; CELL TO CELL VARIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENTROPY; GENE EXPRESSION PROFILING; LIMIT OF QUANTITATION; NONHUMAN; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE CELL ANALYSIS; UPREGULATION; BIOLOGICAL MODEL; CYTOLOGY; METABOLISM; STEM CELL;

CELL DIFFERENTIATION; ENTROPY; GENE EXPRESSION PROFILING; MODELS, BIOLOGICAL; SINGLE-CELL ANALYSIS; STEM CELLS;

EID: 85009145060     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1002585     Document Type: Article

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