Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors

Cell Stem Cell

Volumn 17, Issue 4, 2015, Pages 422-434

  Haas, Simon ^a,b   Hansson, Jenny ^c   Klimmeck, Daniel ^a,b,c   Loeffler, Dirk ^d   Velten, Lars ^c   Uckelmann, Hannah ^a,b   Wurzer, Stephan ^a,b   Prendergast, Áine M ^a,b   Schnell, Alexandra ^a,b   Hexel, Klaus ^b   Santarella Mellwig, Rachel ^c   Blaszkiewicz, Sandra ^a,b   Kuck, Andrea ^a,b   Geiger, Hartmut ^e,f   Milsom, Michael D ^a,b   Steinmetz, Lars M ^c,g   Schroeder, Timm ^d   Trumpp, Andreas ^a,b   Krijgsveld, Jeroen ^c   Essers, Marieke A G ^a,b  

^a Exp Hematology Group Heidelberg Institute for Stem Cell Technology and Experimental Medicine GGmbH   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d ETH ZURICH   (Switzerland)

^e UNIVERSITY OF ULM   (Germany)

^f UNIVERSITY OF CINCINNATI   (United States)

^g STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA TUBULIN; BETA1 TUBULIN; FIBRINOGEN RECEPTOR; INITIATION FACTOR 4A; LIPOPOLYSACCHARIDE; MAMMALIAN TARGET OF RAPAMYCIN; POLYINOSINIC POLYCYTIDYLIC ACID; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; STAT1 PROTEIN; STEM CELL ANTIGEN 1; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL CYCLE; CELL DIFFERENTIATION; CELL MATURATION; CELL REGENERATION; CELL SELECTION; CYTOKINE PRODUCTION; FLUORESCENCE ACTIVATED CELL SORTING; FLUORESCENCE MICROSCOPY; HEMATOPOIETIC STEM CELL; HOMEOSTASIS; INFLAMMATION; MASS SPECTROMETRY; MEGAKARYOBLAST; MEGAKARYOPOIESIS; MOUSE; NONHUMAN; PHENOTYPE; PLATELET DEPLETION; PLATELET MICROPARTICLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEOMICS; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE COUNT; UPREGULATION; ANIMAL; CELL LINEAGE; CELL PROLIFERATION; PATHOLOGY; PHYSIOLOGY; THROMBOCYTOPOIESIS;

ANIMALS; BLOOD PLATELETS; CELL LINEAGE; CELL PROLIFERATION; HEMATOPOIETIC STEM CELLS; INFLAMMATION; MEGAKARYOCYTE PROGENITOR CELLS; MICE; THROMBOPOIESIS;

EID: 84952628356     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2015.07.007     Document Type: Article

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