Cell signalling regulates dynamics of Nanog distribution in embryonic stem cell populations

Journal of the Royal Society Interface

Volumn 10, Issue 78, 2013, Pages

  Luo, Yang ^a   Lim, Chea Lu ^b,c   Nichols, Jennifer ^b   Martinez Arias, Alfonso ^b   Wernisch, Lorenz ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITI BRUNEI DARUSSALAM   (Brunei Darussalam)

Author keywords

Embryonic stem cell; Nanog regulation; Stochastic system

Indexed keywords

CELL PROLIFERATION; DYNAMICAL SYSTEMS; DYNAMICS; GENE EXPRESSION; SIGNAL TRANSDUCTION; STEM CELLS; STOCHASTIC SYSTEMS;

, INHIBITOR; CELL LINES; CELL POPULATIONS; CELL SIGNALLING; CELLULAR MECHANISMS; COMBINED EFFECT; CULTURE CONDITIONS; DETERMINISTIC COMPONENT; EMBRYONIC STEM CELLS; ES CELLS; INDIVIDUAL CELLS; KEY FEATURE; LARGE SHIFTS; LOW LEVEL; NANOG REGULATION; PLURIPOTENCY; SIGNALLING MECHANISMS; SIGNALLING PATHWAYS; SINGLE CELLS; STABLE STEADY STATE; STATIONARY STATE; STEADY STATE; STOCHASTIC DYNAMICAL SYSTEM; SYNTHETIC INHIBITORS;

CELL CULTURE;

TRANSCRIPTION FACTOR NANOG; GLYCOGEN SYNTHASE KINASE 3; GREEN FLUORESCENT PROTEIN; HOMEODOMAIN PROTEIN; HYBRID PROTEIN; NANOG PROTEIN, MOUSE;

ARTICLE; CELL CULTURE; CELL POPULATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; INTRACELLULAR SIGNALING; PROTEIN LOCALIZATION; STEADY STATE; STOCHASTIC MODEL; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE TECHNIQUE; CELL LINE; CYTOLOGY; GENETICS; METABOLISM; MOUSE; MOUSE EMBRYONIC STEM CELL; PHYSIOLOGY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANIMALS; CELL CULTURE TECHNIQUES; CELL LINE; GLYCOGEN SYNTHASE KINASE 3; GREEN FLUORESCENT PROTEINS; HOMEODOMAIN PROTEINS; MAP KINASE SIGNALING SYSTEM; MICE; MODELS, BIOLOGICAL; MOUSE EMBRYONIC STEM CELLS; NANOG HOMEOBOX PROTEIN; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS;

EID: 84871348952     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2012.0525     Document Type: Article

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