Tunability and noise dependence in differentiation dynamics

Science

Volumn 315, Issue 5819, 2007, Pages 1716-1719

  Süel, Gürol M ^a   Kulkarni, Rajan P ^b   Dworkin, Jonathan ^c   Garcia Ojalvo, Jordi ^d   Elowitz, Michael B ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b California Institute of Technology   (United States)

^c Columbia University ^*  (United States)

^d UNIVERSITAT POLITÈCNICA DE CATALUNYA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM; CORRELATION; EXPERIMENTAL STUDY; NOISE;

ARTICLE; BACILLUS SUBTILIS; BACTERIAL GENETICS; CELL DIFFERENTIATION; CORRELATION ANALYSIS; DYNAMICS; NOISE; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; PROBABILITY;

BACILLUS SUBTILIS; BACTERIAL PROTEINS; GENE EXPRESSION; GENES, BACTERIAL; ISOPROPYL THIOGALACTOSIDE; LUMINESCENT PROTEINS; MATHEMATICS; MODELS, GENETIC; MODELS, STATISTICAL; MUTATION; PROBABILITY; PROMOTER REGIONS, GENETIC; TRANSCRIPTION FACTORS; TRANSFORMATION, BACTERIAL;

BACILLUS SUBTILIS;

EID: 34047118521     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1137455     Document Type: Article

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25. We thank R. Kishony, B. Shraiman, U. Alon, R. Ranganathan, S. Altschuler, L. Wu, and K. Süel, together with members of the Elowitz laboratory, for thoughtful comments and discussions. This work was supported by grants from NIH (R01 GM079771 to M.B.E. and GM068763 to the Center for Modular Biology), the Searle Scholars Program, the Human Frontiers Science Program, and the Packard Foundation. G.M.S. is supported by California Institute of Technology Center for Biological Circuit Design and the University of Texas Southwestern's Endowed Scholars Program. J.G.O. acknowledges financial support from the Ministerio de Educadon y Ciencia (Spain, project FIS2006-11452) and from the Generalitat de Catalunya.