Quantifying the contribution of chromatin dynamics to stochastic gene expression reveals long, locus-dependent periods between transcriptional bursts

BMC Biology

Volumn 11, Issue , 2013, Pages

  Viñuelas, José ^a   Kaneko, Gaël ^a,b   Coulon, Antoine ^c   Vallin, Elodie ^a   Morin, Valérie ^a   Mejia Pous, Camila ^a   Kupiec, Jean Jacques ^d   Beslon, Guillaume ^b   Gandrillon, Olivier ^a  

^a CENTRE DE GÉNÉTIQUE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITÉ DE LYON   (France)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d ECOLE NORMALE SUPÉRIEURE   (France)

Author keywords

Chromatin dynamics; Expression noise; Gene regulation; Stochastic model

Indexed keywords

EUKARYOTA;

HYDROXAMIC ACID; MESSENGER RNA; PHOTOPROTEIN; RED FLUORESCENT PROTEIN; TRICHOSTATIN A;

ALGORITHM; ANIMAL; ARTICLE; BIOLOGICAL MODEL; CELL LINE; CHICKEN; CHROMATIN; COMPUTER SIMULATION; DRUG EFFECT; FLUORESCENCE; GENE EXPRESSION REGULATION; GENE LOCUS; GENETIC TRANSCRIPTION; GENETICS; GENOME; METABOLISM; REPORTER GENE; REPRODUCIBILITY; STATISTICS; TIME;

ALGORITHMS; ANIMALS; CELL LINE; CHICKENS; CHROMATIN; COMPUTER SIMULATION; FLUORESCENCE; GENE EXPRESSION REGULATION; GENES, REPORTER; GENETIC LOCI; GENOME; HYDROXAMIC ACIDS; LUMINESCENT PROTEINS; MODELS, GENETIC; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; STOCHASTIC PROCESSES; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 84874149579     PISSN: None     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/1741-7007-11-15     Document Type: Article

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