-
1
-
-
28944449341
-
Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets
-
Arnould, S., Chames, P., Perez, C., Lacroix, E., Duclert, A., Epinat, J.-C., Stricher, F., Petit, A.-S., Patin, A., Guillier, S. et al. (2006). Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets. J. Mol. Biol. 355, 443-458.
-
(2006)
J. Mol. Biol.
, vol.355
, pp. 443-458
-
-
Arnould, S.1
Chames, P.2
Perez, C.3
Lacroix, E.4
Duclert, A.5
Epinat, J.-C.6
Stricher, F.7
Petit, A.-S.8
Patin, A.9
Guillier, S.10
-
2
-
-
34047118522
-
CRISPR provides acquired resistance against viruses in prokaryotes
-
Barrangou, R., Fremaux, C., Deveau, H., Richards, M., Boyaval, P., Moineau, S., Romero, D. A. and Horvath, P. (2007). CRISPR provides acquired resistance against viruses in prokaryotes. Science 315, 1709-1712.
-
(2007)
Science
, vol.315
, pp. 1709-1712
-
-
Barrangou, R.1
Fremaux, C.2
Deveau, H.3
Richards, M.4
Boyaval, P.5
Moineau, S.6
Romero, D.A.7
Horvath, P.8
-
3
-
-
84928775846
-
A prudent path forward for genomic engineering and germline gene modification
-
Baltimore, D., Berg, P., Botchan, M., Carroll, D., Charo, R. A., Church, G., Corn, J. E., Daley, G. Q., Doudna, J. A., Fenner, M. et al. (2015). A prudent path forward for genomic engineering and germline gene modification. Science 348, 36-38.
-
(2015)
Science
, vol.348
, pp. 36-38
-
-
Baltimore, D.1
Berg, P.2
Botchan, M.3
Carroll, D.4
Charo, R.A.5
Church, G.6
Corn, J.E.7
Daley, G.Q.8
Doudna, J.A.9
Fenner, M.10
-
4
-
-
84942163495
-
Defining the three cell lineages of the human blastocyst by single-cell RNA-seq
-
Blakeley, P., Fogarty, N. M. E., del Valle, I., Wamaitha, S. E., Hu, T. X., Elder, K., Snell, P., Christie, L., Robson, P. and Niakan, K. K. (2015). Defining the three cell lineages of the human blastocyst by single-cell RNA-seq. Development 142, 3151-3165.
-
(2015)
Development
, vol.142
, pp. 3151-3165
-
-
Blakeley, P.1
Fogarty, N.M.E.2
del Valle, I.3
Wamaitha, S.E.4
Hu, T.X.5
Elder, K.6
Snell, P.7
Christie, L.8
Robson, P.9
Niakan, K.K.10
-
5
-
-
84867241738
-
Maternal Cdx2 is dispensable for mouse development
-
Blij, S., Frum, T., Akyol, A., Fearon, E. and Ralston, A. (2012). Maternal Cdx2 is dispensable for mouse development. Development 139, 3969-3972.
-
(2012)
Development
, vol.139
, pp. 3969-3972
-
-
Blij, S.1
Frum, T.2
Akyol, A.3
Fearon, E.4
Ralston, A.5
-
6
-
-
84890805562
-
Biallelic genome modification in F0 Xenopus tropicalis embryos using the CRISPR/Cas system
-
Blitz, I. L., Biesinger, J., Xie, X. and Cho, K. W. Y. (2013). Biallelic genome modification in F0 Xenopus tropicalis embryos using the CRISPR/Cas system. Genesis 51, 827-834.
-
(2013)
Genesis
, vol.51
, pp. 827-834
-
-
Blitz, I.L.1
Biesinger, J.2
Xie, X.3
Cho, K.W.Y.4
-
7
-
-
79960064013
-
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
-
Cermak, T., Doyle, E. L., Christian, M., Wang, L., Zhang, Y., Schmidt, C., Baller, J. A., Somia, N. V., Bogdanove, A. J. and Voytas, D. F. (2011). Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. Nucleic Acids Res. 39, 7879.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 7879
-
-
Cermak, T.1
Doyle, E.L.2
Christian, M.3
Wang, L.4
Zhang, Y.5
Schmidt, C.6
Baller, J.A.7
Somia, N.V.8
Bogdanove, A.J.9
Voytas, D.F.10
-
8
-
-
84894063115
-
Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system
-
Chen, B., Gilbert, L. A., Cimini, B. A., Schnitzbauer, J., Zhang, W., Li, G.-W., Park, J., Blackburn, E. H., Weissman, J. S., Qi, L. S. et al. (2013). Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system. Cell 155, 1479-1491.
-
(2013)
Cell
, vol.155
, pp. 1479-1491
-
-
Chen, B.1
Gilbert, L.A.2
Cimini, B.A.3
Schnitzbauer, J.4
Zhang, W.5
Li, G.-W.6
Park, J.7
Blackburn, E.H.8
Weissman, J.S.9
Qi, L.S.10
-
9
-
-
84891710947
-
Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases
-
Cho, S.W., Kim, S., Kim, Y., Kweon, J., Kim, H. S., Bae, S. and Kim, J.-S. (2014). Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases. Genome Res. 24, 132-141.
-
(2014)
Genome Res.
, vol.24
, pp. 132-141
-
-
Cho, S.W.1
Kim, S.2
Kim, Y.3
Kweon, J.4
Kim, H.S.5
Bae, S.6
Kim, J.-S.7
-
10
-
-
84873729095
-
Multiplex Genome Engineering Using CRISPR/Cas Systems
-
Cong, L., Ran, F. A., Cox, D., Lin, S., Barretto, R., Habib, N., Hsu, P. D., Wu, X., Jiang, W., Marraffini, L. A. et al. (2013). Multiplex Genome Engineering Using CRISPR/Cas Systems. Science 339, 819-823.
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Hsu, P.D.7
Wu, X.8
Jiang, W.9
Marraffini, L.A.10
-
11
-
-
84969256720
-
Self-organization of the in vitro attached human embryo
-
Deglincerti, A., Croft, G. F., Pietila, L. N., Zernicka-Goetz, M., Siggia, E. D. and Brivanlou, A. H. (2016). Self-organization of the in vitro attached human embryo. Nature 533, 251-254.
-
(2016)
Nature
, vol.533
, pp. 251-254
-
-
Deglincerti, A.1
Croft, G.F.2
Pietila, L.N.3
Zernicka-Goetz, M.4
Siggia, E.D.5
Brivanlou, A.H.6
-
12
-
-
84942845731
-
CASFISH:CRISPR/Cas9-mediated in situ labeling of genomic loci in fixed cells
-
Deng, W., Shi, X., Tjian, R., Lionnet, T. and Singer, R. H. (2015). CASFISH:CRISPR/Cas9-mediated in situ labeling of genomic loci in fixed cells. Proc. Natl. Acad. Sci. USA 112, 11870-11875.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. 11870-11875
-
-
Deng, W.1
Shi, X.2
Tjian, R.3
Lionnet, T.4
Singer, R.H.5
-
13
-
-
0031863007
-
Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic doublestrand breaks in mouse embryonic stem cells
-
Donoho, G., Jasin, M. and Berg, P. (1998). Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic doublestrand breaks in mouse embryonic stem cells. Mol. Cell. Biol. 18, 4070-4078.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 4070-4078
-
-
Donoho, G.1
Jasin, M.2
Berg, P.3
-
14
-
-
84947976287
-
The primatespecific noncoding RNA HPAT5 regulates pluripotency during human preimplantation development and nuclear reprogramming
-
Durruthy-Durruthy, J., Sebastiano, V., Wossidlo, M., Cepeda, D., Cui, J., Grow, E. J., Davila, J., Mall, M., Wong, W. H., Wysocka, J. et al. (2016). The primatespecific noncoding RNA HPAT5 regulates pluripotency during human preimplantation development and nuclear reprogramming. Nat. Genet. 48, 44-52.
-
(2016)
Nat. Genet.
, vol.48
, pp. 44-52
-
-
Durruthy-Durruthy, J.1
Sebastiano, V.2
Wossidlo, M.3
Cepeda, D.4
Cui, J.5
Grow, E.J.6
Davila, J.7
Mall, M.8
Wong, W.H.9
Wysocka, J.10
-
15
-
-
84880571335
-
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes
-
Gilbert, L. A., Larson, M. H., Morsut, L., Liu, Z., Brar, G. A., Torres, S. E., Stern-Ginossar, N., Brandman, O., Whitehead, E. H., Doudna, J. A. et al. (2013). CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes. Cell 154, 442-451.
-
(2013)
Cell
, vol.154
, pp. 442-451
-
-
Gilbert, L.A.1
Larson, M.H.2
Morsut, L.3
Liu, Z.4
Brar, G.A.5
Torres, S.E.6
Stern-Ginossar, N.7
Brandman, O.8
Whitehead, E.H.9
Doudna, J.A.10
-
16
-
-
84884165315
-
DNA targeting specificity of RNA-guided Cas9 nucleases
-
Hsu, P. D., Scott, D. A., Weinstein, J. A., Ran, F. A., Konermann, S., Agarwala, V., Li, Y., Fine, E. J., Wu, X., Shalem, O. et al. (2013). DNA targeting specificity of RNA-guided Cas9 nucleases. Nat. Biotechnol. 31, 827-832.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 827-832
-
-
Hsu, P.D.1
Scott, D.A.2
Weinstein, J.A.3
Ran, F.A.4
Konermann, S.5
Agarwala, V.6
Li, Y.7
Fine, E.J.8
Wu, X.9
Shalem, O.10
-
17
-
-
84882788354
-
Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system
-
Jao, L.-E., Wente, S. R. and Chen, W. (2013). Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system. Proc. Natl. Acad. Sci. USA 110, 13904-13909.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 13904-13909
-
-
Jao, L.-E.1
Wente, S.R.2
Chen, W.3
-
18
-
-
84865070369
-
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
-
Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J. A. and Charpentier, E. (2012). A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337, 816-821.
-
(2012)
Science
, vol.337
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.6
-
19
-
-
84962641038
-
Introducing precise genetic modifications into human 3PN embryos by CRISPR/ Cas-mediated genome editing
-
Kang, X., He,W., Huang, Y., Yu, Q., Chen, Y., Gao, X., Sun, X. and Fan, Y. (2016). Introducing precise genetic modifications into human 3PN embryos by CRISPR/ Cas-mediated genome editing. J. Assist. Reprod. Genet. 33, 581-588.
-
(2016)
J. Assist. Reprod. Genet.
, vol.33
, pp. 581-588
-
-
Kang, X.1
He, W.2
Huang, Y.3
Yu, Q.4
Chen, Y.5
Gao, X.6
Sun, X.7
Fan, Y.8
-
20
-
-
0030032063
-
Hybrid restriction enzymes: Zinc finger fusions to Fok I cleavage domain
-
Kim, Y. G., Cha, J. and Chandrasegaran, S. (1996). Hybrid restriction enzymes:zinc finger fusions to Fok I cleavage domain. Proc. Natl. Acad. Sci. USA 93, 1156-1160.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1156-1160
-
-
Kim, Y.G.1
Cha, J.2
Chandrasegaran, S.3
-
21
-
-
84963941043
-
High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects
-
Kleinstiver, B. P., Pattanayak, V., Prew, M. S., Tsai, S. Q., Nguyen, N. T., Zheng, Z. and Joung, J. K. (2016). High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects. Nature 529, 490-495.
-
(2016)
Nature
, vol.529
, pp. 490-495
-
-
Kleinstiver, B.P.1
Pattanayak, V.2
Prew, M.S.3
Tsai, S.Q.4
Nguyen, N.T.5
Zheng, Z.6
Joung, J.K.7
-
22
-
-
84923096541
-
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
-
Konermann, S., Brigham, M. D., Trevino, A. E., Joung, J., Abudayyeh, O. O., Barcena, C., Hsu, P. D., Habib, N., Gootenberg, J. S., Nishimasu, H. et al. (2014). Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. Nature 517, 583-588.
-
(2014)
Nature
, vol.517
, pp. 583-588
-
-
Konermann, S.1
Brigham, M.D.2
Trevino, A.E.3
Joung, J.4
Abudayyeh, O.O.5
Barcena, C.6
Hsu, P.D.7
Habib, N.8
Gootenberg, J.S.9
Nishimasu, H.10
-
23
-
-
84856689924
-
The roles of FGF and MAP kinase signaling in the segregation of the epiblast and hypoblast cell lineages in bovine and human embryos
-
Kuijk, E. W., van Tol, L. T. A., Van de Velde, H., Wubbolts, R., Welling, M., Geijsen, N. and Roelen, B. A. J. (2012). The roles of FGF and MAP kinase signaling in the segregation of the epiblast and hypoblast cell lineages in bovine and human embryos. Development 139, 871-882.
-
(2012)
Development
, vol.139
, pp. 871-882
-
-
Kuijk, E.W.1
van Tol, L.T.A.2
Van de Velde, H.3
Wubbolts, R.4
Welling, M.5
Geijsen, N.6
Roelen, B.A.J.7
-
24
-
-
84928775204
-
Don’t edit the human germ line
-
Lanphier, E., Urnov, F., Haecker, S. E., Werner, M. and Smolenski, J. (2015). Don’t edit the human germ line. Nature 519, 410-411.
-
(2015)
Nature
, vol.519
, pp. 410-411
-
-
Lanphier, E.1
Urnov, F.2
Haecker, S.E.3
Werner, M.4
Smolenski, J.5
-
25
-
-
84886993480
-
CRISPR interference (CRISPRi) for sequence-specific control of gene expression
-
Larson, M. H., Gilbert, L. A., Wang, X., Lim, W. A., Weissman, J. S. and Qi, L. S. (2013). CRISPR interference (CRISPRi) for sequence-specific control of gene expression. Nat. Protoc. 8, 2180-2196.
-
(2013)
Nat. Protoc.
, vol.8
, pp. 2180-2196
-
-
Larson, M.H.1
Gilbert, L.A.2
Wang, X.3
Lim, W.A.4
Weissman, J.S.5
Qi, L.S.6
-
26
-
-
84930618439
-
CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes
-
Liang, P., Xu, Y., Zhang, X., Ding, C., Huang, R., Zhang, Z., Lv, J., Xie, X., Chen, Y., Li, Y. et al. (2015). CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes. Protein Cell 6, 363-372.
-
(2015)
Protein Cell
, vol.6
, pp. 363-372
-
-
Liang, P.1
Xu, Y.2
Zhang, X.3
Ding, C.4
Huang, R.5
Zhang, Z.6
Lv, J.7
Xie, X.8
Chen, Y.9
Li, Y.10
-
27
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali, P., Yang, L., Esvelt, K. M., Aach, J., Guell, M., DiCarlo, J. E., Norville, J. E. and Church, G. M. (2013). RNA-guided human genome engineering via Cas9. Science 339, 823-827.
-
(2013)
Science
, vol.339
, pp. 823-827
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
DiCarlo, J.E.6
Norville, J.E.7
Church, G.M.8
-
28
-
-
0027237167
-
Transcription at different salinities of Haloferax mediterranei sequences adjacent to partially modified PstI sites
-
Mojica, F. J. M., Juez, G. and Rodriguez-Valera, F. (1993). Transcription at different salinities of Haloferax mediterranei sequences adjacent to partially modified PstI sites. Mol. Microbiol. 9, 613-621.
-
(1993)
Mol. Microbiol.
, vol.9
, pp. 613-621
-
-
Mojica, F.J.M.1
Juez, G.2
Rodriguez-Valera, F.3
-
29
-
-
0029166294
-
Long stretches of short tandem repeats are present in the largest replicons of the Archaea Haloferax mediterranei and Haloferax volcanii and could be involved in replicon partitioning
-
Mojica, F. J. M., Ferrer, C., Juez, G. and Rodríguez-Valera, F. (1995). Long stretches of short tandem repeats are present in the largest replicons of the Archaea Haloferax mediterranei and Haloferax volcanii and could be involved in replicon partitioning. Mol. Microbiol. 17, 85-93.
-
(1995)
Mol. Microbiol.
, vol.17
, pp. 85-93
-
-
Mojica, F.J.M.1
Ferrer, C.2
Juez, G.3
Rodríguez-Valera, F.4
-
30
-
-
84873524509
-
Analysis of human embryos from zygote to blastocyst reveals distinct gene expression patterns relative to the mouse
-
Niakan, K. K. and Eggan, K. (2013). Analysis of human embryos from zygote to blastocyst reveals distinct gene expression patterns relative to the mouse. Dev. Biol. 375, 54-64.
-
(2013)
Dev. Biol.
, vol.375
, pp. 54-64
-
-
Niakan, K.K.1
Eggan, K.2
-
31
-
-
84894081986
-
Generation of gene-modified cynomolgus monkey via Cas9/ RNA-mediated gene targeting in one-cell embryos
-
Niu, Y., Shen, B., Cui, Y., Chen, Y.,Wang, J.,Wang, L., Kang, Y., Zhao, X., Si,W., Li, W. et al. (2014). Generation of gene-modified cynomolgus monkey via Cas9/ RNA-mediated gene targeting in one-cell embryos. Cell 156, 836-843.
-
(2014)
Cell
, vol.156
, pp. 836-843
-
-
Niu, Y.1
Shen, B.2
Cui, Y.3
Chen, Y.4
Wang, J.5
Wang, L.6
Kang, Y.7
Zhao, X.8
Si, W.9
Li, W.10
-
32
-
-
84884155038
-
High-throughput profiling of off-target DNA cleavage reveals RNAprogrammed Cas9 nuclease specificity
-
Pattanayak, V., Lin, S., Guilinger, J. P., Ma, E., Doudna, J. A. and Liu, D. R. (2013). High-throughput profiling of off-target DNA cleavage reveals RNAprogrammed Cas9 nuclease specificity. Nat. Biotechnol. 31, 839-843.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 839-843
-
-
Pattanayak, V.1
Lin, S.2
Guilinger, J.P.3
Ma, E.4
Doudna, J.A.5
Liu, D.R.6
-
33
-
-
84962688754
-
Singlecell RNA-seq reveals lineage and X chromosome dynamics in human preimplantation embryos
-
Petropoulos, S., Edsgård, D., Reinius, B., Deng, Q., Panula, S. P., Codeluppi, S., Plaza Reyes, A., Linnarsson, S., Sandberg, R. and Lanner, F. (2015). Singlecell RNA-seq reveals lineage and X chromosome dynamics in human preimplantation embryos. Cell 165, 1012-1026.
-
(2015)
Cell
, vol.165
, pp. 1012-1026
-
-
Petropoulos, S.1
Edsgård, D.2
Reinius, B.3
Deng, Q.4
Panula, S.P.5
Codeluppi, S.6
Plaza Reyes, A.7
Linnarsson, S.8
Sandberg, R.9
Lanner, F.10
-
34
-
-
84874687019
-
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
-
Qi, L. S., Larson, M. H., Gilbert, L. A., Doudna, J. A.,Weissman, J. S., Arkin, A. P. and Lim, W. A. (2013). Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell 152, 1173-1183.
-
(2013)
Cell
, vol.152
, pp. 1173-1183
-
-
Qi, L.S.1
Larson, M.H.2
Gilbert, L.A.3
Doudna, J.A.4
Weissman, J.S.5
Arkin, A.P.6
Lim, W.A.7
-
35
-
-
84884288934
-
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity
-
Ran, F. A., Hsu, P. D., Lin, C. Y., Gootenberg, J. S., Konermann, S., Trevino, A. E., Scott, D. A., Inoue, A., Matoba, S., Zhang, Y. et al. (2013). Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell 154, 1380-1389.
-
(2013)
Cell
, vol.154
, pp. 1380-1389
-
-
Ran, F.A.1
Hsu, P.D.2
Lin, C.Y.3
Gootenberg, J.S.4
Konermann, S.5
Trevino, A.E.6
Scott, D.A.7
Inoue, A.8
Matoba, S.9
Zhang, Y.10
-
36
-
-
84355166507
-
Human hypoblast formation is not dependent on FGF signalling
-
Roode, M., Blair, K., Snell, P., Elder, K., Marchant, S., Smith, A. and Nichols, J. (2012). Human hypoblast formation is not dependent on FGF signalling. Dev. Biol. 361, 358-363.
-
(2012)
Dev. Biol.
, vol.361
, pp. 358-363
-
-
Roode, M.1
Blair, K.2
Snell, P.3
Elder, K.4
Marchant, S.5
Smith, A.6
Nichols, J.7
-
37
-
-
0024693555
-
Genetic and physical analysis of double-strand break repair and recombination in Saccharomyces cerevisiae
-
Rudin, N., Sugarman, E. and Haber, J. E. (1989). Genetic and physical analysis of double-strand break repair and recombination in Saccharomyces cerevisiae. Genetics 122, 519-534.
-
(1989)
Genetics
, vol.122
, pp. 519-534
-
-
Rudin, N.1
Sugarman, E.2
Haber, J.E.3
-
38
-
-
80755145195
-
The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli
-
Sapranauskas, R., Gasiunas, G., Fremaux, C., Barrangou, R., Horvath, P. and Siksnys, V. (2011). The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli. Nucleic Acids Res. 39, 9275-9282.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 9275-9282
-
-
Sapranauskas, R.1
Gasiunas, G.2
Fremaux, C.3
Barrangou, R.4
Horvath, P.5
Siksnys, V.6
-
39
-
-
0031032549
-
Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination
-
Sargent, R. G., Brenneman, M. A. and Wilson, J. H. (1997). Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination. Mol. Cell. Biol. 17, 267-277.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 267-277
-
-
Sargent, R.G.1
Brenneman, M.A.2
Wilson, J.H.3
-
40
-
-
84965074868
-
Selforganization of the human embryo in the absence of maternal tissues
-
Shahbazi, M. N., Jedrusik, A., Vuoristo, S., Recher, G., Hupalowska, A., Bolton, V., Fogarty, N. M. E., Campbell, A., Devito, L. G., Ilic, D. et al. (2016). Selforganization of the human embryo in the absence of maternal tissues. Nat. Cell Biol. 18, 700-708.
-
(2016)
Nat. Cell Biol.
, vol.18
, pp. 700-708
-
-
Shahbazi, M.N.1
Jedrusik, A.2
Vuoristo, S.3
Recher, G.4
Hupalowska, A.5
Bolton, V.6
Fogarty, N.M.E.7
Campbell, A.8
Devito, L.G.9
Ilic, D.10
-
41
-
-
84952943845
-
Rationally engineered Cas9 nucleases with improved specificity
-
Slaymaker, I. M., Gao, L., Zetsche, B., Scott, D. A., Yan, W. X. and Zhang, F. (2015). Rationally engineered Cas9 nucleases with improved specificity. Science 351, 84-88.
-
(2015)
Science
, vol.351
, pp. 84-88
-
-
Slaymaker, I.M.1
Gao, L.2
Zetsche, B.3
Scott, D.A.4
Yan, W.X.5
Zhang, F.6
-
42
-
-
84946511041
-
Asymmetric parental genome engineering by Cas9 during mouse meiotic exit
-
Suzuki, T., Asami, M. and Perry, A. C. F. (2014). Asymmetric parental genome engineering by Cas9 during mouse meiotic exit. Sci. Rep. 4, 7621.
-
(2014)
Sci. Rep.
, vol.4
, pp. 7621
-
-
Suzuki, T.1
Asami, M.2
Perry, A.C.F.3
-
44
-
-
0023043553
-
Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene
-
Thomas, K. R. and Capecchi, M. R. (1986). Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene. Nature 324, 34-38.
-
(1986)
Nature
, vol.324
, pp. 34-38
-
-
Thomas, K.R.1
Capecchi, M.R.2
-
45
-
-
0022542596
-
High frequency targeting of genes to specific sites in the mammalian genome
-
Thomas, K. R., Folger, K. R. and Capecchi, M. R. (1986). High frequency targeting of genes to specific sites in the mammalian genome. Cell 44, 419-428.
-
(1986)
Cell
, vol.44
, pp. 419-428
-
-
Thomas, K.R.1
Folger, K.R.2
Capecchi, M.R.3
-
46
-
-
84941347016
-
Novel PRD-like homeodomain transcription factors and retrotransposon elements in early human development
-
Töhönen, V., Katayama, S., Vesterlund, L., Jouhilahti, E.-M., Sheikhi, M., Madissoon, E., Filippini-Cattaneo, G., Jaconi, M., Johnsson, A., Bürglin, T. R. et al. (2015). Novel PRD-like homeodomain transcription factors and retrotransposon elements in early human development. Nat. Commun. 6, 8207.
-
(2015)
Nat. Commun.
, vol.6
, pp. 8207
-
-
Töhönen, V.1
Katayama, S.2
Vesterlund, L.3
Jouhilahti, E.-M.4
Sheikhi, M.5
Madissoon, E.6
Filippini-Cattaneo, G.7
Jaconi, M.8
Johnsson, A.9
Bürglin, T.R.10
-
47
-
-
18944373328
-
Highly efficient endogenous human gene correction using designed zinc-finger nucleases
-
Urnov, F. D., Miller, J. C., Lee, Y.-L., Beausejour, C. M., Rock, J. M., Augustus, S., Jamieson, A. C., Porteus, M. H., Gregory, P. D. and Holmes, M. C. (2005). Highly efficient endogenous human gene correction using designed zinc-finger nucleases. Nature 435, 646-651.
-
(2005)
Nature
, vol.435
, pp. 646-651
-
-
Urnov, F.D.1
Miller, J.C.2
Lee, Y.-L.3
Beausejour, C.M.4
Rock, J.M.5
Augustus, S.6
Jamieson, A.C.7
Porteus, M.H.8
Gregory, P.D.9
Holmes, M.C.10
-
48
-
-
79961029892
-
XCI in preimplantation mouse and human embryos: First there is remodelling…
-
van den Berg, I. M., Galjaard, R. J., Laven, J. S. E. and van Doorninck, J. H. (2011). XCI in preimplantation mouse and human embryos: first there is remodelling…. Hum. Genet. 130, 203-215.
-
(2011)
Hum. Genet.
, vol.130
, pp. 203-215
-
-
van den Berg, I.M.1
Galjaard, R.J.2
Laven, J.S.E.3
van Doorninck, J.H.4
-
49
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
-
Wang, H., Yang, H., Shivalila, C. S., Dawlaty, M. M., Cheng, A.W., Zhang, F. and Jaenisch, R. (2013). One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153, 910-918.
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
Zhang, F.6
Jaenisch, R.7
-
50
-
-
84920269807
-
Correction of a genetic disease by CRISPRCas9-mediated gene editing in mouse spermatogonial stem cells
-
Wu, Y., Zhou, H., Fan, X., Zhang, Y., Zhang, M.,Wang, Y., Xie, Z., Bai, M., Yin, Q., Liang, D. et al. (2015). Correction of a genetic disease by CRISPRCas9-mediated gene editing in mouse spermatogonial stem cells. Cell Res. 25, 67-79.
-
(2015)
Cell Res.
, vol.25
, pp. 67-79
-
-
Wu, Y.1
Zhou, H.2
Fan, X.3
Zhang, Y.4
Zhang, M.5
Wang, Y.6
Xie, Z.7
Bai, M.8
Yin, Q.9
Liang, D.10
-
51
-
-
84883134780
-
Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing
-
Xue, Z., Huang, K., Cai, C., Cai, L., Jiang, C.-Y., Feng, Y., Liu, Z., Zeng, Q., Cheng, L., Sun, Y. E. et al. (2013). Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing. Nature 500, 593-597.
-
(2013)
Nature
, vol.500
, pp. 593-597
-
-
Xue, Z.1
Huang, K.2
Cai, C.3
Cai, L.4
Jiang, C.-Y.5
Feng, Y.6
Liu, Z.7
Zeng, Q.8
Cheng, L.9
Sun, Y.E.10
-
52
-
-
84883743509
-
Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells
-
Yan, L., Yang, M., Guo, H., Yang, L., Wu, J., Li, R., Liu, P., Lian, Y., Zheng, X., Yan, J. et al. (2013). Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells. Nat. Struct. Mol. Biol. 20, 1131-1139.
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 1131-1139
-
-
Yan, L.1
Yang, M.2
Guo, H.3
Yang, L.4
Wu, J.5
Li, R.6
Liu, P.7
Lian, Y.8
Zheng, X.9
Yan, J.10
-
53
-
-
84905732049
-
Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes
-
Yen, S.-T., Zhang, M., Deng, J. M., Usman, S. J., Smith, C. N., Parker-Thornburg, J., Swinton, P. G., Martin, J. F. and Behringer, R. R. (2014). Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes. Dev. Biol. 393, 3-9.
-
(2014)
Dev. Biol.
, vol.393
, pp. 3-9
-
-
Yen, S.-T.1
Zhang, M.2
Deng, J.M.3
Usman, S.J.4
Smith, C.N.5
Parker-Thornburg, J.6
Swinton, P.G.7
Martin, J.F.8
Behringer, R.R.9
|