Defining the three cell lineages of the human blastocyst by single-cell RNA-seq

Development (Cambridge)

Volumn 142, Issue 18, 2015, Pages 3151-3165

  Blakeley, Paul ^a   Fogarty, Norah M E ^a   Del Valle, Ignacio ^a   Wamaitha, Sissy E ^a   Hu, Tim Xiaoming ^b,c   Elder, Kay ^d   Snell, Philip ^d   Christie, Leila ^d   Robson, Paul ^b,e   Niakan, Kathy K ^a  

^a THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^b GENOME INSTITUTE OF SINGAPORE   (Singapore)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d Bourn Hall Clinic   (United Kingdom)

^e JACKSON LABORATORY   (United States)

Author keywords

Embryonic stem cells; Epiblast; Human; Mouse; RNA sequencing; Trophectoderm

Indexed keywords

GROWTH DIFFERENTIATION FACTOR 3; LEFTY1 PROTEIN; PROTEIN; PROTEIN NODAL; SMAD2 PROTEIN; SMAD4 PROTEIN; TDGF1 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLASTOCYST; CELL LINEAGE; CONTROLLED STUDY; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; ENDODERM; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN DEVELOPMENT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLURIPOTENT EPIBLAST; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; RNA SEQUENCE; VALIDATION STUDY; ANIMAL; CYTOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; PHYSIOLOGY; PRINCIPAL COMPONENT ANALYSIS; PROCEDURES; SEQUENCE ANALYSIS; SINGLE CELL ANALYSIS; SPECIES DIFFERENCE;

ANIMALS; BLASTOCYST; CELL LINEAGE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MICE; PRINCIPAL COMPONENT ANALYSIS; SEQUENCE ANALYSIS, RNA; SINGLE-CELL ANALYSIS; SPECIES SPECIFICITY;

EID: 84942163495     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.123547     Document Type: Article

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