Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination

Journal of Experimental Medicine

Volumn 214, Issue 1, 2017, Pages 245-267

  Fang, Xiaoguang ^a   Zhou, Wenchao ^a   Wu, Qiulian ^a   Huang, Zhi ^a   Shi, Yu ^a,b   Yang, Kailin ^a   Chen, Cong ^a,b   Xie, Qi ^a   Mack, Stephen C ^a   Wang, Xiuxing ^a   Carcaboso, Angel M ^c   Sloan, Andrew E ^d,e   Ouyang, Gaoliang ^f   McLendon, Roger E ^g   Bian, Xiu Wu ^b   Rich, Jeremy N ^a,e   Bao, Shideng ^a,e  

^a LERNER RESEARCH INSTITUTE   (United States)

^b SOUTHWEST HOSPITAL   (China)

^c Preclinical Therapeutics and Drug Delivery Research Program   (Spain)

^d UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^e CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f XIAMEN UNIVERSITY   (China)

^g DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEUBIQUITINASE; DEUBIQUITINASE USPO13; F BOX PROTEIN; FBXL14 PROTEIN; MYC PROTEIN; TUMOR PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; FBXL14 PROTEIN, HUMAN; PROTEINASE; UBIQUITIN PROTEIN LIGASE; USP13 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; ECTOPIC EXPRESSION; GENE OVEREXPRESSION; GLIOBLASTOMA; GLIOMA STEM CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STABILITY; STEM CELL SELF-RENEWAL; TUMOR DIFFERENTIATION; TUMOR GROWTH; UBIQUITINATION; ANTAGONISTS AND INHIBITORS; BRAIN TUMOR; CANCER STEM CELL; CELL PROLIFERATION; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; ENDOPEPTIDASES; F-BOX PROTEINS; GLIOBLASTOMA; HUMANS; NEOPLASTIC STEM CELLS; PROTO-ONCOGENE PROTEINS C-MYC; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 85008426303     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20151673     Document Type: Article

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