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Volumn 13, Issue 2, 2011, Pages 142-152

Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells

Author keywords

[No Author keywords available]

Indexed keywords

BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; HERPES VIRUS ASSOCIATED UBIQUITIN SPECIFIC PROTEASE; REPRESSOR ELEMENT 1 SILENCING TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

EID: 79551600613     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb2153     Document Type: Article
Times cited : (127)

References (34)
  • 1
    • 0028934541 scopus 로고
    • REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons
    • Chong, J. A. et al. REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell 80, 949-957 (1995).
    • (1995) Cell , vol.80 , pp. 949-957
    • Chong, J.A.1
  • 2
    • 0028968802 scopus 로고
    • The neuron-restrictive silencer factor (NRSF): A coordinate repressor of multiple neuron-specific genes
    • Schoenherr, C. J. & Anderson, D. J. The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes. Science 267, 1360-1363 (1995).
    • (1995) Science , vol.267 , pp. 1360-1363
    • Schoenherr, C.J.1    Anderson, D.J.2
  • 3
    • 19344378337 scopus 로고    scopus 로고
    • REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis
    • Ballas, N., Grunseich, C., Lu, D. D., Speh, J. C. & Mandel, G. REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell 121, 645-657 (2005).
    • (2005) Cell , vol.121 , pp. 645-657
    • Ballas, N.1    Grunseich, C.2    Lu, D.D.3    Speh, J.C.4    Mandel, G.5
  • 4
    • 70449578270 scopus 로고    scopus 로고
    • Differential deployment of REST and CoREST promotes glial subtypes specification and oligodendrocyte lineage maturation
    • Abrajano, J. J. et al. Differential deployment of REST and CoREST promotes glial subtypes specification and oligodendrocyte lineage maturation. PLoS One 4, e7665 (2010).
    • (2010) PLoS One , vol.4
    • Abrajano, J.J.1
  • 5
    • 41149119961 scopus 로고    scopus 로고
    • SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation
    • Westbrook, T. F. et al. SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation. Nature 452, 370-374 (2008).
    • (2008) Nature , vol.452 , pp. 370-374
    • Westbrook, T.F.1
  • 6
    • 41149130221 scopus 로고    scopus 로고
    • Control of chromosome stability by the β-TrCP-REST-Mad2 axis
    • Guardavaccaro, D. et al. Control of chromosome stability by the β-TrCP-REST-Mad2 axis. Nature 452, 365-369 (2008).
    • (2008) Nature , vol.452 , pp. 365-369
    • Guardavaccaro, D.1
  • 7
    • 25844518743 scopus 로고    scopus 로고
    • The many faces of REST oversee epigenetic programming of neuronal genes
    • Ballas, N. & Mandel, G. The many faces of REST oversee epigenetic programming of neuronal genes. Curr. Opin. Neurobiol. 15, 500-506 (2005).
    • (2005) Curr. Opin. Neurobiol. , vol.15 , pp. 500-506
    • Ballas, N.1    Mandel, G.2
  • 8
    • 54949103985 scopus 로고    scopus 로고
    • REST regulates distinct transcriptional networks in embryonic and neural stem cells
    • Johnson, R. et al. REST regulates distinct transcriptional networks in embryonic and neural stem cells. PLoS Biol. 6, 2205-2219 (2008).
    • (2008) PLoS Biol. , vol.6 , pp. 2205-2219
    • Johnson, R.1
  • 9
    • 0041353535 scopus 로고    scopus 로고
    • Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
    • Zuccato, C. et al. Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Nat. Genet. 35, 76-83 (2003).
    • (2003) Nat. Genet. , vol.35 , pp. 76-83
    • Zuccato, C.1
  • 10
    • 64549130400 scopus 로고    scopus 로고
    • Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
    • Lepagnol-Bestel, A. M. et al. Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Hum. Mol. Genet. 18, 1405-1414 (2009).
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 1405-1414
    • Lepagnol-Bestel, A.M.1
  • 11
    • 34249900454 scopus 로고    scopus 로고
    • The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation
    • Tahiliani, M. et al. The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature 447, 601-605 (2007).
    • (2007) Nature , vol.447 , pp. 601-605
    • Tahiliani, M.1
  • 12
    • 51149115754 scopus 로고    scopus 로고
    • DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome
    • Canzonetta, C. et al. DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome. Am. J. Hum. Genet. 83, 388-400 (2008).
    • (2008) Am. J. Hum. Genet. , vol.83 , pp. 388-400
    • Canzonetta, C.1
  • 13
    • 0033942317 scopus 로고    scopus 로고
    • The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells
    • Lawinger, P. et al. The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells. Nat. Med. 6, 826-831 (2000).
    • (2000) Nat. Med. , vol.6 , pp. 826-831
    • Lawinger, P.1
  • 14
    • 33644518372 scopus 로고    scopus 로고
    • Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation
    • Su, X. et al. Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation. Mol. Cell Biol. 26, 1666-1678 (2006).
    • (2006) Mol. Cell Biol. , vol.26 , pp. 1666-1678
    • Su, X.1
  • 15
    • 15944374306 scopus 로고    scopus 로고
    • Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16
    • Fuller, G. N. et al. Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16. Mol. Cancer Ther. 4, 343-349 (2005).
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 343-349
    • Fuller, G.N.1
  • 16
    • 20444376939 scopus 로고    scopus 로고
    • A genetic screen for candidate tumor suppressors identifies REST
    • Westbrook, T. et al. A genetic screen for candidate tumor suppressors identifies REST. Cell 121, 837-848 (2005).
    • (2005) Cell , vol.121 , pp. 837-848
    • Westbrook, T.1
  • 17
    • 0041529593 scopus 로고    scopus 로고
    • Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7
    • Holowaty, M. N. et al. Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7. J. Biol. Chem. 278, 29987-29994 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 29987-29994
    • Holowaty, M.N.1
  • 18
    • 25144467949 scopus 로고    scopus 로고
    • Reciprocal activities between herpes simplex virus type 1 regulatory protein ICP0, a ubiquitin E3 ligase, and ubiquitin-specific protease USP7
    • Boutell, C., Canning, M., Orr, A. & Everett, R. D. Reciprocal activities between herpes simplex virus type 1 regulatory protein ICP0, a ubiquitin E3 ligase, and ubiquitin-specific protease USP7. J. Virol. 79, 12342-12354 (2005).
    • (2005) J. Virol. , vol.79 , pp. 12342-12354
    • Boutell, C.1    Canning, M.2    Orr, A.3    Everett, R.D.4
  • 19
    • 0033578299 scopus 로고    scopus 로고
    • CoREST: A functional corepressor required for regulation of neural-specific gene expression
    • Andres, M. E. et al. CoREST: a functional corepressor required for regulation of neural-specific gene expression. Proc. Natl Acad. Sci. USA 96, 9873-9878 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 9873-9878
    • Andres, M.E.1
  • 20
    • 33749188883 scopus 로고    scopus 로고
    • FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP
    • Van der Horst, A. et al. FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP. Nat. Cell Biol. 8, 1064-1073 (2006).
    • (2006) Nat. Cell Biol. , vol.8 , pp. 1064-1073
    • Van Der Horst, A.1
  • 21
    • 33644808087 scopus 로고    scopus 로고
    • Molecular recognition of p53 and MDM2 by USP7/HAUSP
    • Sheng, Y. et al. Molecular recognition of p53 and MDM2 by USP7/HAUSP. Nat. Struct. Mol. Biol. 13, 285-291 (2006).
    • (2006) Nat. Struct. Mol. Biol. , vol.13 , pp. 285-291
    • Sheng, Y.1
  • 22
    • 20144386721 scopus 로고    scopus 로고
    • Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization
    • Saridakis, V. et al. Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization. Mol. Cell 18, 25-36 (2005).
    • (2005) Mol. Cell , vol.18 , pp. 25-36
    • Saridakis, V.1
  • 23
    • 1842421376 scopus 로고    scopus 로고
    • A dynamic role of HAUSP in the p53-Mdm2 pathway
    • Li, M., Brooks, C. L., Kon, N. & Gu, W. A dynamic role of HAUSP in the p53-Mdm2 pathway. Mol. Cell 13, 879-886 (2004).
    • (2004) Mol. Cell , vol.13 , pp. 879-886
    • Li, M.1    Brooks, C.L.2    Kon, N.3    Gu, W.4
  • 24
    • 4644331227 scopus 로고    scopus 로고
    • Tumour suppression: Disruption of HAUSP gene stabilizes p53
    • Cummins, J. M. et al. Tumour suppression: disruption of HAUSP gene stabilizes p53. Nature 428, 6982 (2004).
    • (2004) Nature , vol.428 , pp. 6982
    • Cummins, J.M.1
  • 25
    • 53649106156 scopus 로고    scopus 로고
    • The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network
    • Song, M. S. et al. The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network. Nature 455, 813-817 (2008).
    • (2008) Nature , vol.455 , pp. 813-817
    • Song, M.S.1
  • 26
    • 65549095495 scopus 로고    scopus 로고
    • REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells
    • Jorgensen, H. F. et al. REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells. Development 136, 715-721 (2009).
    • (2009) Development , vol.136 , pp. 715-721
    • Jorgensen, H.F.1
  • 27
    • 0031694917 scopus 로고    scopus 로고
    • NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis
    • Chen, Z. F., Paquette, A. J. & Anderson, D. J. NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis. Nat. Genet. 20, 136-142 (1998).
    • (1998) Nat. Genet. , vol.20 , pp. 136-142
    • Chen, Z.F.1    Paquette, A.J.2    Anderson, D.J.3
  • 28
    • 43449100341 scopus 로고    scopus 로고
    • REST maintains self-renewal and pluripotency of embryonic stem cells
    • Singh, S. K., Kagalwala, M. N., Parker-Thornburg, J., Adams, H. & Majumder, S. REST maintains self-renewal and pluripotency of embryonic stem cells. Nature 453, 223-227 (2008).
    • (2008) Nature , vol.453 , pp. 223-227
    • Singh, S.K.1    Kagalwala, M.N.2    Parker-Thornburg, J.3    Adams, H.4    Majumder, S.5
  • 30
    • 73349091835 scopus 로고    scopus 로고
    • Rest promotes the early differentiation of mouse ESCs but is not required for their maintenance
    • Yamada, Y., Aoki, H., Kunisada, T. & Hara, A. Rest promotes the early differentiation of mouse ESCs but is not required for their maintenance. Cell Stem Cell 6, 10-15 (2010).
    • (2010) Cell Stem Cell , vol.6 , pp. 10-15
    • Yamada, Y.1    Aoki, H.2    Kunisada, T.3    Hara, A.4
  • 31
    • 53249087743 scopus 로고    scopus 로고
    • Nontelomeric TRF2-REST interaction modulates neuronal gene silencing and fate of tumor and stem cells
    • Zhang, P. et al. Nontelomeric TRF2-REST interaction modulates neuronal gene silencing and fate of tumor and stem cells. Curr. Biol. 18, 1489-1494 (2008).
    • (2008) Curr. Biol. , vol.18 , pp. 1489-1494
    • Zhang, P.1
  • 32
    • 33845317573 scopus 로고    scopus 로고
    • Cancer stem cells promote radioresistance of malignant glioma through preferential activation of DNA damage checkpoint and repair
    • Bao, S. et al. Cancer stem cells promote radioresistance of malignant glioma through preferential activation of DNA damage checkpoint and repair. Nature 444, 756-760 (2006).
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1
  • 33
    • 51049101689 scopus 로고    scopus 로고
    • Targeting cancer stem cells through L1CAM suppresses glioma growth
    • Bao, S. et al. Targeting cancer stem cells through L1CAM suppresses glioma growth. Cancer Res. 68, 6043-6048 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 6043-6048
    • Bao, S.1
  • 34
    • 65749106405 scopus 로고    scopus 로고
    • Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
    • Li, Z. et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 15, 501-513 (2009).
    • (2009) Cancer Cell , vol.15 , pp. 501-513
    • Li, Z.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.