-
1
-
-
0028934541
-
REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons
-
Chong, J. A. et al. REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell 80, 949-957 (1995).
-
(1995)
Cell
, vol.80
, pp. 949-957
-
-
Chong, J.A.1
-
2
-
-
0028968802
-
The neuron-restrictive silencer factor (NRSF): A coordinate repressor of multiple neuron-specific genes
-
Schoenherr, C. J. & Anderson, D. J. The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes. Science 267, 1360-1363 (1995).
-
(1995)
Science
, vol.267
, pp. 1360-1363
-
-
Schoenherr, C.J.1
Anderson, D.J.2
-
3
-
-
19344378337
-
REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis
-
Ballas, N., Grunseich, C., Lu, D. D., Speh, J. C. & Mandel, G. REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell 121, 645-657 (2005).
-
(2005)
Cell
, vol.121
, pp. 645-657
-
-
Ballas, N.1
Grunseich, C.2
Lu, D.D.3
Speh, J.C.4
Mandel, G.5
-
4
-
-
70449578270
-
Differential deployment of REST and CoREST promotes glial subtypes specification and oligodendrocyte lineage maturation
-
Abrajano, J. J. et al. Differential deployment of REST and CoREST promotes glial subtypes specification and oligodendrocyte lineage maturation. PLoS One 4, e7665 (2010).
-
(2010)
PLoS One
, vol.4
-
-
Abrajano, J.J.1
-
5
-
-
41149119961
-
SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation
-
Westbrook, T. F. et al. SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation. Nature 452, 370-374 (2008).
-
(2008)
Nature
, vol.452
, pp. 370-374
-
-
Westbrook, T.F.1
-
6
-
-
41149130221
-
Control of chromosome stability by the β-TrCP-REST-Mad2 axis
-
Guardavaccaro, D. et al. Control of chromosome stability by the β-TrCP-REST-Mad2 axis. Nature 452, 365-369 (2008).
-
(2008)
Nature
, vol.452
, pp. 365-369
-
-
Guardavaccaro, D.1
-
7
-
-
25844518743
-
The many faces of REST oversee epigenetic programming of neuronal genes
-
Ballas, N. & Mandel, G. The many faces of REST oversee epigenetic programming of neuronal genes. Curr. Opin. Neurobiol. 15, 500-506 (2005).
-
(2005)
Curr. Opin. Neurobiol.
, vol.15
, pp. 500-506
-
-
Ballas, N.1
Mandel, G.2
-
8
-
-
54949103985
-
REST regulates distinct transcriptional networks in embryonic and neural stem cells
-
Johnson, R. et al. REST regulates distinct transcriptional networks in embryonic and neural stem cells. PLoS Biol. 6, 2205-2219 (2008).
-
(2008)
PLoS Biol.
, vol.6
, pp. 2205-2219
-
-
Johnson, R.1
-
9
-
-
0041353535
-
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
-
Zuccato, C. et al. Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Nat. Genet. 35, 76-83 (2003).
-
(2003)
Nat. Genet.
, vol.35
, pp. 76-83
-
-
Zuccato, C.1
-
10
-
-
64549130400
-
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
-
Lepagnol-Bestel, A. M. et al. Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Hum. Mol. Genet. 18, 1405-1414 (2009).
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 1405-1414
-
-
Lepagnol-Bestel, A.M.1
-
11
-
-
34249900454
-
The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation
-
Tahiliani, M. et al. The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature 447, 601-605 (2007).
-
(2007)
Nature
, vol.447
, pp. 601-605
-
-
Tahiliani, M.1
-
12
-
-
51149115754
-
DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome
-
Canzonetta, C. et al. DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome. Am. J. Hum. Genet. 83, 388-400 (2008).
-
(2008)
Am. J. Hum. Genet.
, vol.83
, pp. 388-400
-
-
Canzonetta, C.1
-
13
-
-
0033942317
-
The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells
-
Lawinger, P. et al. The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells. Nat. Med. 6, 826-831 (2000).
-
(2000)
Nat. Med.
, vol.6
, pp. 826-831
-
-
Lawinger, P.1
-
14
-
-
33644518372
-
Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation
-
Su, X. et al. Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation. Mol. Cell Biol. 26, 1666-1678 (2006).
-
(2006)
Mol. Cell Biol.
, vol.26
, pp. 1666-1678
-
-
Su, X.1
-
15
-
-
15944374306
-
Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16
-
Fuller, G. N. et al. Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16. Mol. Cancer Ther. 4, 343-349 (2005).
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 343-349
-
-
Fuller, G.N.1
-
16
-
-
20444376939
-
A genetic screen for candidate tumor suppressors identifies REST
-
Westbrook, T. et al. A genetic screen for candidate tumor suppressors identifies REST. Cell 121, 837-848 (2005).
-
(2005)
Cell
, vol.121
, pp. 837-848
-
-
Westbrook, T.1
-
17
-
-
0041529593
-
Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7
-
Holowaty, M. N. et al. Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7. J. Biol. Chem. 278, 29987-29994 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 29987-29994
-
-
Holowaty, M.N.1
-
18
-
-
25144467949
-
Reciprocal activities between herpes simplex virus type 1 regulatory protein ICP0, a ubiquitin E3 ligase, and ubiquitin-specific protease USP7
-
Boutell, C., Canning, M., Orr, A. & Everett, R. D. Reciprocal activities between herpes simplex virus type 1 regulatory protein ICP0, a ubiquitin E3 ligase, and ubiquitin-specific protease USP7. J. Virol. 79, 12342-12354 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 12342-12354
-
-
Boutell, C.1
Canning, M.2
Orr, A.3
Everett, R.D.4
-
19
-
-
0033578299
-
CoREST: A functional corepressor required for regulation of neural-specific gene expression
-
Andres, M. E. et al. CoREST: a functional corepressor required for regulation of neural-specific gene expression. Proc. Natl Acad. Sci. USA 96, 9873-9878 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 9873-9878
-
-
Andres, M.E.1
-
20
-
-
33749188883
-
FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP
-
Van der Horst, A. et al. FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP. Nat. Cell Biol. 8, 1064-1073 (2006).
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1064-1073
-
-
Van Der Horst, A.1
-
21
-
-
33644808087
-
Molecular recognition of p53 and MDM2 by USP7/HAUSP
-
Sheng, Y. et al. Molecular recognition of p53 and MDM2 by USP7/HAUSP. Nat. Struct. Mol. Biol. 13, 285-291 (2006).
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 285-291
-
-
Sheng, Y.1
-
22
-
-
20144386721
-
Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization
-
Saridakis, V. et al. Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization. Mol. Cell 18, 25-36 (2005).
-
(2005)
Mol. Cell
, vol.18
, pp. 25-36
-
-
Saridakis, V.1
-
23
-
-
1842421376
-
A dynamic role of HAUSP in the p53-Mdm2 pathway
-
Li, M., Brooks, C. L., Kon, N. & Gu, W. A dynamic role of HAUSP in the p53-Mdm2 pathway. Mol. Cell 13, 879-886 (2004).
-
(2004)
Mol. Cell
, vol.13
, pp. 879-886
-
-
Li, M.1
Brooks, C.L.2
Kon, N.3
Gu, W.4
-
24
-
-
4644331227
-
Tumour suppression: Disruption of HAUSP gene stabilizes p53
-
Cummins, J. M. et al. Tumour suppression: disruption of HAUSP gene stabilizes p53. Nature 428, 6982 (2004).
-
(2004)
Nature
, vol.428
, pp. 6982
-
-
Cummins, J.M.1
-
25
-
-
53649106156
-
The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network
-
Song, M. S. et al. The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network. Nature 455, 813-817 (2008).
-
(2008)
Nature
, vol.455
, pp. 813-817
-
-
Song, M.S.1
-
26
-
-
65549095495
-
REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells
-
Jorgensen, H. F. et al. REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells. Development 136, 715-721 (2009).
-
(2009)
Development
, vol.136
, pp. 715-721
-
-
Jorgensen, H.F.1
-
27
-
-
0031694917
-
NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis
-
Chen, Z. F., Paquette, A. J. & Anderson, D. J. NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis. Nat. Genet. 20, 136-142 (1998).
-
(1998)
Nat. Genet.
, vol.20
, pp. 136-142
-
-
Chen, Z.F.1
Paquette, A.J.2
Anderson, D.J.3
-
28
-
-
43449100341
-
REST maintains self-renewal and pluripotency of embryonic stem cells
-
Singh, S. K., Kagalwala, M. N., Parker-Thornburg, J., Adams, H. & Majumder, S. REST maintains self-renewal and pluripotency of embryonic stem cells. Nature 453, 223-227 (2008).
-
(2008)
Nature
, vol.453
, pp. 223-227
-
-
Singh, S.K.1
Kagalwala, M.N.2
Parker-Thornburg, J.3
Adams, H.4
Majumder, S.5
-
29
-
-
61349137510
-
Is REST a regulator of pluripotency?
-
Buckley, N. J., Johnson, R., Sun, Y. M. & Stanton, L. W. Is REST a regulator of pluripotency? Nature 457, E5-E6 (2009).
-
(2009)
Nature
, vol.457
-
-
Buckley, N.J.1
Johnson, R.2
Sun, Y.M.3
Stanton, L.W.4
-
30
-
-
73349091835
-
Rest promotes the early differentiation of mouse ESCs but is not required for their maintenance
-
Yamada, Y., Aoki, H., Kunisada, T. & Hara, A. Rest promotes the early differentiation of mouse ESCs but is not required for their maintenance. Cell Stem Cell 6, 10-15 (2010).
-
(2010)
Cell Stem Cell
, vol.6
, pp. 10-15
-
-
Yamada, Y.1
Aoki, H.2
Kunisada, T.3
Hara, A.4
-
31
-
-
53249087743
-
Nontelomeric TRF2-REST interaction modulates neuronal gene silencing and fate of tumor and stem cells
-
Zhang, P. et al. Nontelomeric TRF2-REST interaction modulates neuronal gene silencing and fate of tumor and stem cells. Curr. Biol. 18, 1489-1494 (2008).
-
(2008)
Curr. Biol.
, vol.18
, pp. 1489-1494
-
-
Zhang, P.1
-
32
-
-
33845317573
-
Cancer stem cells promote radioresistance of malignant glioma through preferential activation of DNA damage checkpoint and repair
-
Bao, S. et al. Cancer stem cells promote radioresistance of malignant glioma through preferential activation of DNA damage checkpoint and repair. Nature 444, 756-760 (2006).
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
-
33
-
-
51049101689
-
Targeting cancer stem cells through L1CAM suppresses glioma growth
-
Bao, S. et al. Targeting cancer stem cells through L1CAM suppresses glioma growth. Cancer Res. 68, 6043-6048 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 6043-6048
-
-
Bao, S.1
-
34
-
-
65749106405
-
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
-
Li, Z. et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 15, 501-513 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 501-513
-
-
Li, Z.1
|