-
1
-
-
52649138958
-
UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover
-
doi: 10.1016/j.cell.2008.06.048
-
Alexandru G, Graumann J, Smith GT, Kolawa NJ, Fang R, Deshaies RJ. 2008. UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover. Cell 134:804-816. doi: 10.1016/j.cell.2008.06.048.
-
(2008)
Cell
, vol.134
, pp. 804-816
-
-
Alexandru, G.1
Graumann, J.2
Smith, G.T.3
Kolawa, N.J.4
Fang, R.5
Deshaies, R.J.6
-
2
-
-
39349083915
-
Adapting proteostasis for disease intervention
-
doi: 10.1126/science.1141448
-
Balch WE, Morimoto RI, Dillin A, Kelly JW. 2008. Adapting proteostasis for disease intervention. Science 319:916-919. doi: 10.1126/science.1141448.
-
(2008)
Science
, vol.319
, pp. 916-919
-
-
Balch, W.E.1
Morimoto, R.I.2
Dillin, A.3
Kelly, J.W.4
-
3
-
-
33845917801
-
The role of a novel p97/valosin-containing protein-interacting motif of gp78 in endoplasmic reticulum-associated degradation
-
doi: 10.1074/jbc.M603355200
-
Ballar P, Shen Y, Yang H, Fang S. 2006. The role of a novel p97/valosin-containing protein-interacting motif of gp78 in endoplasmic reticulum-associated degradation. Journal of Biological Chemistry 281:35359-35368. doi: 10.1074/jbc.M603355200.
-
(2006)
Journal of Biological Chemistry
, vol.281
, pp. 35359-35368
-
-
Ballar, P.1
Shen, Y.2
Yang, H.3
Fang, S.4
-
4
-
-
0035658442
-
HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins
-
doi: 10.1091/mbc.12.12.4114
-
Bays NW, Wilhovsky SK, Goradia A, Hodgkiss-Harlow K, Hampton RY. 2001. HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins. Molecular Biology of the Cell 12:4114-4128. doi: 10.1091/mbc.12.12.4114.
-
(2001)
Molecular Biology of the Cell
, vol.12
, pp. 4114-4128
-
-
Bays, N.W.1
Wilhovsky, S.K.2
Goradia, A.3
Hodgkiss-Harlow, K.4
Hampton, R.Y.5
-
5
-
-
84860750274
-
Ubiquitin-specific protease 25 functions in Endoplasmic Reticulum-associated degradation
-
doi: 10.1371/journal.pone.0036542
-
Blount JR, Burr AA, Denuc A, Marfany G, Todi SV. 2012. Ubiquitin-specific protease 25 functions in Endoplasmic Reticulum-associated degradation. PLOS ONE 7:e36542. doi: 10.1371/journal.pone.0036542.
-
(2012)
PLOS ONE
, vol.7
-
-
Blount, J.R.1
Burr, A.A.2
Denuc, A.3
Marfany, G.4
Todi, S.V.5
-
6
-
-
78149482323
-
Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p
-
doi: 10.1016/j.cell.2010.10.028
-
Carvalho P, Stanley AM, Rapoport TA. 2010. Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p. Cell 143:579-591. doi: 10.1016/j.cell.2010.10.028.
-
(2010)
Cell
, vol.143
, pp. 579-591
-
-
Carvalho, P.1
Stanley, A.M.2
Rapoport, T.A.3
-
7
-
-
84871680407
-
Structures of the Sgt2/SGTA dimerization domain with the Get5/UBL4A UBL domain reveal an interaction that forms a conserved dynamic interface
-
doi: 10.1016/j.celrep.2012.10.010
-
Chartron JW, Vandervelde DG, Clemons WM Jnr. 2012. Structures of the Sgt2/SGTA dimerization domain with the Get5/UBL4A UBL domain reveal an interaction that forms a conserved dynamic interface. Cell Reports 2:1620-1632. doi: 10.1016/j.celrep.2012.10.010.
-
(2012)
Cell Reports
, vol.2
, pp. 1620-1632
-
-
Chartron, J.W.1
Vandervelde, D.G.2
Clemons Jr., W.M.3
-
8
-
-
31044437051
-
The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site
-
doi: 10.1073/pnas.0506618103
-
Chen B, Mariano J, Tsai YC, Chan AH, Cohen M, Weissman AM. 2006. The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site. Proceedings of the Montana Academy of Sciences of the United States of America 103:341-346. doi: 10.1073/pnas.0506618103.
-
(2006)
Proceedings of the Montana Academy of Sciences of the United States of America
, vol.103
, pp. 341-346
-
-
Chen, B.1
Mariano, J.2
Tsai, Y.C.3
Chan, A.H.4
Cohen, M.5
Weissman, A.M.6
-
9
-
-
84866558646
-
gp78: A multifaceted ubiquitin ligase that integrates a unique protein degradation pathway from the endoplasmic reticulum
-
doi: 10.2174/138920312802430590
-
Chen Z, Du S, Fang S. 2012. gp78: a multifaceted ubiquitin ligase that integrates a unique protein degradation pathway from the endoplasmic reticulum. Current Protein & Peptide Science 13:414-424. doi: 10.2174/138920312802430590.
-
(2012)
Current Protein & Peptide Science
, vol.13
, pp. 414-424
-
-
Chen, Z.1
Du, S.2
Fang, S.3
-
10
-
-
84255169603
-
Defining human ERAD networks through an integrative mapping strategy
-
doi: 10.1038/ncb2383
-
Christianson JC, Olzmann JA, Shaler TA, Sowa ME, Bennett EJ, Richter CM, Tyler RE, Greenblatt EJ, Harper JW, Kopito RR. 2011. Defining human ERAD networks through an integrative mapping strategy. Nature Cell Biology 14:93-105. doi: 10.1038/ncb2383.
-
(2011)
Nature Cell Biology
, vol.14
, pp. 93-105
-
-
Christianson, J.C.1
Olzmann, J.A.2
Shaler, T.A.3
Sowa, M.E.4
Bennett, E.J.5
Richter, C.M.6
Tyler, R.E.7
Greenblatt, E.J.8
Harper, J.W.9
Kopito, R.R.10
-
11
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
doi: 10.1126/science.1231143
-
Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F. 2013. Multiplex genome engineering using CRISPR/Cas systems. Science 339:819-823. doi: 10.1126/science.1231143.
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Hsu, P.D.7
Wu, X.8
Jiang, W.9
Marraffini, L.A.10
Zhang, F.11
-
12
-
-
67649964217
-
RING domain E3 ubiquitin ligases
-
doi: 10.1146/annurev.biochem.78.101807.093809
-
Deshaies RJ, Joazeiro CA. 2009. RING domain E3 ubiquitin ligases. Annual Review of Biochemistry 78:399-434. doi: 10.1146/annurev.biochem.78.101807.093809.
-
(2009)
Annual Review of Biochemistry
, vol.78
, pp. 399-434
-
-
Deshaies, R.J.1
Joazeiro, C.A.2
-
13
-
-
84862770830
-
Regulation of TGF-beta signal transduction by mono-and deubiquitylation of Smads
-
doi: 10.1016/j.febslet.2012.03.037
-
Dupont S, Inui M, Newfeld SJ. 2012. Regulation of TGF-beta signal transduction by mono-and deubiquitylation of Smads. FEBS Letters 586:1913-1920. doi: 10.1016/j.febslet.2012.03.037.
-
(2012)
FEBS Letters
, vol.586
, pp. 1913-1920
-
-
Dupont, S.1
Inui, M.2
Newfeld, S.J.3
-
14
-
-
84858004513
-
USP15 stabilizes TGF-beta receptor I and promotes oncogenesis through the activation of TGF-beta signaling in glioblastoma
-
doi: 10.1038/nm.2619
-
Eichhorn PJ, Rodon L, Gonzalez-Junca A, Dirac A, Gili M, Martinez-Saez E, Aura C, Barba I, Peg V, Prat A, Cuartas I, Jimenez J, Garcia-Dorado D, Sahuquillo J, Bernards R, Baselga J, Seoane J. 2012. USP15 stabilizes TGF-beta receptor I and promotes oncogenesis through the activation of TGF-beta signaling in glioblastoma. Nature Medicine 18:429-435. doi: 10.1038/nm.2619.
-
(2012)
Nature Medicine
, vol.18
, pp. 429-435
-
-
Eichhorn, P.J.1
Rodon, L.2
Gonzalez-Junca, A.3
Dirac, A.4
Gili, M.5
Martinez-Saez, E.6
Aura, C.7
Barba, I.8
Peg, V.9
Prat, A.10
Cuartas, I.11
Jimenez, J.12
Garcia-Dorado, D.13
Sahuquillo, J.14
Bernards, R.15
Baselga, J.16
Seoane, J.17
-
15
-
-
70349778618
-
The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER
-
doi: 10.1016/j.molcel.2009.09.016
-
Ernst R, Mueller B, Ploegh HL, Schlieker C. 2009. The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER. Molecular Cell 36:28-38. doi: 10.1016/j.molcel.2009.09.016.
-
(2009)
Molecular Cell
, vol.36
, pp. 28-38
-
-
Ernst, R.1
Mueller, B.2
Ploegh, H.L.3
Schlieker, C.4
-
16
-
-
0035807839
-
The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum
-
doi: 10.1073/pnas.251401598
-
Fang S, Ferrone M, Yang C, Jensen JP, Tiwari S, Weissman AM. 2001. The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum. Proceedings of the Montana Academy of Sciences of the United States of America 98:14422-14427. doi: 10.1073/pnas.251401598.
-
(2001)
Proceedings of the Montana Academy of Sciences of the United States of America
, vol.98
, pp. 14422-14427
-
-
Fang, S.1
Ferrone, M.2
Yang, C.3
Jensen, J.P.4
Tiwari, S.5
Weissman, A.M.6
-
17
-
-
1642505493
-
Dissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatin
-
doi: 10.1091/mbc.E03-07-0506
-
Fiebiger E, Hirsch C, Vyas JM, Gordon E, Ploegh HL, Tortorella D. 2004. Dissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatin. Molecular Biology of the Cell 15:1635-1646. doi: 10.1091/mbc.E03-07-0506.
-
(2004)
Molecular Biology of the Cell
, vol.15
, pp. 1635-1646
-
-
Fiebiger, E.1
Hirsch, C.2
Vyas, J.M.3
Gordon, E.4
Ploegh, H.L.5
Tortorella, D.6
-
18
-
-
33744967943
-
A ubiquitin-interacting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome
-
doi: 10.1038/ncb1402
-
Flick K, Raasi S, Zhang H, Yen JL, Kaiser P. 2006. A ubiquitin-interacting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome. Nature Cell Biology 8:509-515. doi: 10.1038/ncb1402.
-
(2006)
Nature Cell Biology
, vol.8
, pp. 509-515
-
-
Flick, K.1
Raasi, S.2
Zhang, H.3
Yen, J.L.4
Kaiser, P.5
-
19
-
-
0041315902
-
Polyubiquitin serves as a recognition signal, rather than a ratcheting molecule, during retrotranslocation of proteins across the endoplasmic reticulum membrane
-
doi: 10.1074/jbc.M303360200
-
Flierman D, Ye Y, Dai M, Chau V, Rapoport TA. 2003. Polyubiquitin serves as a recognition signal, rather than a ratcheting molecule, during retrotranslocation of proteins across the endoplasmic reticulum membrane. The Journal of Biological Chemistry 278:34774-34782. doi: 10.1074/jbc.M303360200.
-
(2003)
The Journal of Biological Chemistry
, vol.278
, pp. 34774-34782
-
-
Flierman, D.1
Ye, Y.2
Dai, M.3
Chau, V.4
Rapoport, T.A.5
-
20
-
-
67650087753
-
The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates
-
doi: 10.1038/embor.2009.69
-
Hassink GC, Zhao B, Sompallae R, Altun M, Gastaldello S, Zinin NV, Masucci MG, Lindsten K. 2009. The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates. EMBO Reports 10:755-761. doi: 10.1038/embor.2009.69.
-
(2009)
EMBO Reports
, vol.10
, pp. 755-761
-
-
Hassink, G.C.1
Zhao, B.2
Sompallae, R.3
Altun, M.4
Gastaldello, S.5
Zinin, N.V.6
Masucci, M.G.7
Lindsten, K.8
-
21
-
-
79960637590
-
Protein targeting and degradation are coupled for elimination of mislocalized proteins
-
doi: 10.1038/nature10181
-
Hessa T, Sharma A, Mariappan M, Eshleman HD, Gutierrez E, Hegde RS. 2011. Protein targeting and degradation are coupled for elimination of mislocalized proteins. Nature 475:394-397. doi: 10.1038/nature10181.
-
(2011)
Nature
, vol.475
, pp. 394-397
-
-
Hessa, T.1
Sharma, A.2
Mariappan, M.3
Eshleman, H.D.4
Gutierrez, E.5
Hegde, R.S.6
-
22
-
-
63649161943
-
The ubiquitylation machinery of the endoplasmic reticulum
-
doi: 10.1038/nature07962
-
Hirsch C, Gauss R, Horn SC, Neuber O, Sommer T. 2009. The ubiquitylation machinery of the endoplasmic reticulum. Nature 458:453-460. doi: 10.1038/nature07962.
-
(2009)
Nature
, vol.458
, pp. 453-460
-
-
Hirsch, C.1
Gauss, R.2
Horn, S.C.3
Neuber, O.4
Sommer, T.5
-
23
-
-
0036173013
-
Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48
-
doi: 10.1038/ncb746
-
Jarosch E, Taxis C, Volkwein C, Bordallo J, Finley D, Wolf DH, Sommer T. 2002. Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48. Nature Cell Biology 4:134-139. doi: 10.1038/ncb746.
-
(2002)
Nature Cell Biology
, vol.4
, pp. 134-139
-
-
Jarosch, E.1
Taxis, C.2
Volkwein, C.3
Bordallo, J.4
Finley, D.5
Wolf, D.H.6
Sommer, T.7
-
24
-
-
79955406213
-
Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
-
doi: 10.1074/jbc.M110.211326
-
Jo Y, Sguigna PV, Debose-Boyd RA. 2011. Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. The Journal of Biological Chemistry 286:15022-15031. doi: 10.1074/jbc.M110.211326.
-
(2011)
The Journal of Biological Chemistry
, vol.286
, pp. 15022-15031
-
-
Jo, Y.1
Sguigna, P.V.2
Debose-Boyd, R.A.3
-
25
-
-
84875912087
-
Reversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells
-
doi: 10.1038/ncomms2532
-
Lee JG, Baek K, Soetandyo N, Ye Y. 2013. Reversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells. Nature Communications 4:1568. doi: 10.1038/ncomms2532.
-
(2013)
Nature Communications
, vol.4
, pp. 1568
-
-
Lee, J.G.1
Baek, K.2
Soetandyo, N.3
Ye, Y.4
-
26
-
-
84874976264
-
Bag6/Bat3/Scythe: A novel chaperone activity with diverse regulatory functions in protein biogenesis and degradation
-
doi: 10.1002/bies.201200159
-
Lee JG, Ye Y. 2013. Bag6/Bat3/Scythe: a novel chaperone activity with diverse regulatory functions in protein biogenesis and degradation. Bioessays 35:377-385. doi: 10.1002/bies.201200159.
-
(2013)
Bioessays
, vol.35
, pp. 377-385
-
-
Lee, J.G.1
Ye, Y.2
-
27
-
-
43549094447
-
Localization of A20 to a lysosome-associated compartment and its role in NFkappaB signaling
-
doi: 10.1016/j.bbamcr.2008.01.029
-
Li L, Hailey DW, Soetandyo N, LI W, Lippincott-Schwartz J, Shu HB, Ye Y. 2008. Localization of A20 to a lysosome-associated compartment and its role in NFkappaB signaling. Biochimica et Biophysica Acta 1783:1140-1149. doi: 10.1016/j.bbamcr.2008.01.029.
-
(2008)
Biochimica et Biophysica Acta
, vol.1783
, pp. 1140-1149
-
-
Li, L.1
Hailey, D.W.2
Soetandyo, N.3
Li, W.4
Lippincott-Schwartz, J.5
Shu, H.B.6
Ye, Y.7
-
28
-
-
33947243954
-
A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate
-
doi: 10.1038/nature05542
-
Li W, Tu D, Brunger AT, Ye Y. 2007. A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate. Nature 446:333-337. doi: 10.1038/nature05542.
-
(2007)
Nature
, vol.446
, pp. 333-337
-
-
Li, W.1
Tu, D.2
Brunger, A.T.3
Ye, Y.4
-
29
-
-
62649096662
-
Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2
-
doi: 10.1073/pnas.0808564106
-
Li W, Tu D, Li L, Wollert T, Ghirlando R, Brunger AT, Ye Y. 2009. Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2. Proceedings of the Montana Academy of Sciences of the United States of America 106:3722-3727. doi: 10.1073/pnas.0808564106.
-
(2009)
Proceedings of the Montana Academy of Sciences of the United States of America
, vol.106
, pp. 3722-3727
-
-
Li, W.1
Tu, D.2
Li, L.3
Wollert, T.4
Ghirlando, R.5
Brunger, A.T.6
Ye, Y.7
-
30
-
-
84866527405
-
Roles of p97-associated deubiquitinases in protein quality control at the endoplasmic reticulum
-
doi: 10.2174/138920312802430608
-
Liu Y, Ye Y. 2012. Roles of p97-associated deubiquitinases in protein quality control at the endoplasmic reticulum. Current Protein & Peptide Science 13:436-446. doi: 10.2174/138920312802430608.
-
(2012)
Current Protein & Peptide Science
, vol.13
, pp. 436-446
-
-
Liu, Y.1
Ye, Y.2
-
31
-
-
77955878748
-
BAG-6 is essential for selective elimination of defective proteasomal substrates
-
doi: 10.1083/jcb.200908092
-
Minami R, Hayakawa A, Kagawa H, Yanagi Y, Yokosawa H, Kawahara H. 2010. BAG-6 is essential for selective elimination of defective proteasomal substrates. The Journal of Cell Biology 190:637-650. doi: 10.1083/jcb.200908092.
-
(2010)
The Journal of Cell Biology
, vol.190
, pp. 637-650
-
-
Minami, R.1
Hayakawa, A.2
Kagawa, H.3
Yanagi, Y.4
Yokosawa, H.5
Kawahara, H.6
-
32
-
-
33646066025
-
The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin
-
doi: 10.1016/j.cell.2006.02.038
-
Reyes-Turcu FE, Horton JR, Mullally JE, Heroux A, Cheng X, Wilkinson KD. 2006. The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin. Cell 124:1197-1208. doi: 10.1016/j.cell.2006.02.038.
-
(2006)
Cell
, vol.124
, pp. 1197-1208
-
-
Reyes-Turcu, F.E.1
Horton, J.R.2
Mullally, J.E.3
Heroux, A.4
Cheng, X.5
Wilkinson, K.D.6
-
33
-
-
67650620318
-
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes
-
doi: 10.1146/annurev.biochem.78.082307.091526
-
Reyes-Turcu FE, Ventii KH, Wilkinson KD. 2009. Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes. Annual Review of Biochemistry 78:363-397. doi: 10.1146/annurev.biochem.78.082307.091526.
-
(2009)
Annual Review of Biochemistry
, vol.78
, pp. 363-397
-
-
Reyes-Turcu, F.E.1
Ventii, K.H.2
Wilkinson, K.D.3
-
34
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
doi: 10.1038/nrm2199
-
Ron D, Walter P. 2007. Signal integration in the endoplasmic reticulum unfolded protein response. Nature Reviews Molecular Cell Biology 8:519-529. doi: 10.1038/nrm2199.
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
35
-
-
20344394159
-
Deubiquitinating enzyme purification, assay inhibitors, and characterization
-
doi: 10.1385/1-59259-895-1:207
-
Russell NS, Wilkinson KD. 2005. Deubiquitinating enzyme purification, assay inhibitors, and characterization. Methods in Molecular Biology 301:207-219. doi: 10.1385/1-59259-895-1:207.
-
(2005)
Methods in Molecular Biology
, vol.301
, pp. 207-219
-
-
Russell, N.S.1
Wilkinson, K.D.2
-
36
-
-
82255161944
-
Road to ruin: Targeting proteins for degradation in the endoplasmic reticulum
-
doi: 10.1126/science.1209235
-
Smith MH, Ploegh HL, Weissman JS. 2011. Road to ruin: targeting proteins for degradation in the endoplasmic reticulum. Science 334:1086-1090. doi: 10.1126/science.1209235.
-
(2011)
Science
, vol.334
, pp. 1086-1090
-
-
Smith, M.H.1
Ploegh, H.L.2
Weissman, J.S.3
-
37
-
-
77951199047
-
Role of intramembrane charged residues in the quality control of unassembled T-cell receptor alpha-chains at the endoplasmic reticulum
-
doi: 10.1242/jcs.059758
-
Soetandyo N, Wang Q, Ye Y, Li L. 2010. Role of intramembrane charged residues in the quality control of unassembled T-cell receptor alpha-chains at the endoplasmic reticulum. Journal of Cell Science 123:1031-1038. doi: 10.1242/jcs.059758.
-
(2010)
Journal of Cell Science
, vol.123
, pp. 1031-1038
-
-
Soetandyo, N.1
Wang, Q.2
Ye, Y.3
Li, L.4
-
38
-
-
24944591120
-
Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase
-
doi: 10.1016/j.molcel.2005.08.009
-
Song BL, Sever N, Debose-Boyd RA. 2005. Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase. Molecular Cell 19:829-840. doi: 10.1016/j.molcel.2005.08.009.
-
(2005)
Molecular Cell
, vol.19
, pp. 829-840
-
-
Song, B.L.1
Sever, N.2
Debose-Boyd, R.A.3
-
39
-
-
67649634849
-
Defining the human deubiquitinating enzyme interaction landscape
-
doi: 10.1016/j.cell.2009.04.042
-
Sowa ME, Bennett EJ, Gygi SP, Harper JW. 2009. Defining the human deubiquitinating enzyme interaction landscape. Cell 138:389-403. doi: 10.1016/j.cell.2009.04.042.
-
(2009)
Cell
, vol.138
, pp. 389-403
-
-
Sowa, M.E.1
Bennett, E.J.2
Gygi, S.P.3
Harper, J.W.4
-
40
-
-
56749176947
-
One step at a time: Endoplasmic reticulum-associated degradation
-
doi: 10.1038/nrm2546
-
Vembar SS, Brodsky JL. 2008. One step at a time: endoplasmic reticulum-associated degradation. Nature Reviews Molecular Cell Biology 9:944-957. doi: 10.1038/nrm2546.
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, pp. 944-957
-
-
Vembar, S.S.1
Brodsky, J.L.2
-
41
-
-
77957376226
-
A chaperone cascade sorts proteins for posttranslational membrane insertion into the endoplasmic reticulum
-
doi: 10.1016/j.molcel.2010.08.038
-
Wang F, Brown EC, Mak G, Zhuang J, Denic V. 2010. A chaperone cascade sorts proteins for posttranslational membrane insertion into the endoplasmic reticulum. Molecular Cell 40:159-171. doi: 10.1016/j.molcel.2010.08.038.
-
(2010)
Molecular Cell
, vol.40
, pp. 159-171
-
-
Wang, F.1
Brown, E.C.2
Mak, G.3
Zhuang, J.4
Denic, V.5
-
42
-
-
33748988214
-
Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3
-
doi: 10.1083/jcb.200605100
-
Wang Q, Li L, Ye Y. 2006. Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3. The Journal of Cell Biology 174:963-971. doi: 10.1083/jcb.200605100.
-
(2006)
The Journal of Cell Biology
, vol.174
, pp. 963-971
-
-
Wang, Q.1
Li, L.2
Ye, Y.3
-
43
-
-
79959347089
-
A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation
-
doi: 10.1016/j.molcel.2011.05.010
-
Wang Q, Liu Y, Soetandyo N, Baek K, Hegde R, Ye Y. 2011. A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation. Molecular Cell 42:758-770. doi: 10.1016/j.molcel.2011.05.010.
-
(2011)
Molecular Cell
, vol.42
, pp. 758-770
-
-
Wang, Q.1
Liu, Y.2
Soetandyo, N.3
Baek, K.4
Hegde, R.5
Ye, Y.6
-
44
-
-
60549109872
-
ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells
-
doi: 10.1073/pnas.0807611106
-
Wang Q, Mora-Jensen H, Weniger MA, Perez-Galan P, Wolford C, Hai T, Ron D, Chen W, Trenkle W, Wiestner A, Ye Y. 2009. ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells. Proceedings of the Montana Academy of Sciences of the United States of America 106:2200-2205. doi: 10.1073/pnas.0807611106.
-
(2009)
Proceedings of the Montana Academy of Sciences of the United States of America
, vol.106
, pp. 2200-2205
-
-
Wang, Q.1
Mora-Jensen, H.2
Weniger, M.A.3
Perez-Galan, P.4
Wolford, C.5
Hai, T.6
Ron, D.7
Chen, W.8
Trenkle, W.9
Wiestner, A.10
Ye, Y.11
-
45
-
-
84857097177
-
RNA-guided genetic silencing systems in bacteria and archaea
-
doi: 10.1038/nature10886
-
Wiedenheft B, Sternberg SH, Doudna JA. 2012. RNA-guided genetic silencing systems in bacteria and archaea. Nature 482:331-338. doi: 10.1038/nature10886.
-
(2012)
Nature
, vol.482
, pp. 331-338
-
-
Wiedenheft, B.1
Sternberg, S.H.2
Doudna, J.A.3
-
46
-
-
84871682623
-
SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation
-
doi: 10.1016/j.celrep.2012.11.010
-
Xu Y, Cai M, Yang Y, Huang L, Ye Y. 2012. SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation. Cell Reports 2:1633-1644. doi: 10.1016/j.celrep.2012.11.010.
-
(2012)
Cell Reports
, vol.2
, pp. 1633-1644
-
-
Xu, Y.1
Cai, M.2
Yang, Y.3
Huang, L.4
Ye, Y.5
-
47
-
-
84880048596
-
A ubiquitin-like domain recruits an oligomeric chaperone to a retrotranslocation complex in endoplasmic reticulum-associated degradation
-
doi: 10.1074/jbc.M112.449199
-
Xu Y, Liu Y, Lee JG, Ye Y. 2013. A ubiquitin-like domain recruits an oligomeric chaperone to a retrotranslocation complex in endoplasmic reticulum-associated degradation. The Journal of Biological Chemistry 288:18068-18076. doi: 10.1074/jbc.M112.449199.
-
(2013)
The Journal of Biological Chemistry
, vol.288
, pp. 18068-18076
-
-
Xu, Y.1
Liu, Y.2
Lee, J.G.3
Ye, Y.4
-
48
-
-
0035818999
-
The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol
-
doi: 10.1038/414652a
-
Ye Y, Meyer HH, Rapoport TA. 2001. The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature 414:652-656. doi: 10.1038/414652a.
-
(2001)
Nature
, vol.414
, pp. 652-656
-
-
Ye, Y.1
Meyer, H.H.2
Rapoport, T.A.3
-
49
-
-
0038487228
-
Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: Dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains
-
doi: 10.1083/jcb.200302169
-
Ye Y, Meyer HH, Rapoport TA. 2003. Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains. The Journal of Cell Biology 162:71-84. doi: 10.1083/jcb.200302169.
-
(2003)
The Journal of Cell Biology
, vol.162
, pp. 71-84
-
-
Ye, Y.1
Meyer, H.H.2
Rapoport, T.A.3
-
50
-
-
70350461507
-
Building ubiquitin chains: E2 enzymes at work
-
doi: 10.1038/nrm2780
-
Ye Y, Rape M. 2009. Building ubiquitin chains: E2 enzymes at work. Nature Reviews Molecular Cell Biology 10:755-764. doi: 10.1038/nrm2780.
-
(2009)
Nature Reviews Molecular Cell Biology
, vol.10
, pp. 755-764
-
-
Ye, Y.1
Rape, M.2
-
51
-
-
3042677637
-
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
-
doi: 10.1038/nature02656
-
Ye Y, Shibata Y, Yun C, Ron D, Rapoport TA. 2004. A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature 429:841-847. doi: 10.1038/nature02656.
-
(2004)
Nature
, vol.429
, pp. 841-847
-
-
Ye, Y.1
Shibata, Y.2
Yun, C.3
Ron, D.4
Rapoport, T.A.5
-
52
-
-
0030817978
-
Cytosolic degradation of T-cell receptor alpha chains by the proteasome
-
doi: 10.1074/jbc.272.33.20800
-
Yu H, Kaung G, Kobayashi S, Kopito RR. 1997. Cytosolic degradation of T-cell receptor alpha chains by the proteasome. The Journal of Biological Chemistry 272:20800-20804. doi: 10.1074/jbc.272.33.20800.
-
(1997)
The Journal of Biological Chemistry
, vol.272
, pp. 20800-20804
-
-
Yu, H.1
Kaung, G.2
Kobayashi, S.3
Kopito, R.R.4
-
53
-
-
84881150929
-
Deubiquitinases sharpen substrate discrimination during membrane protein degradation from the ER
-
doi: 10.1016/j.cell.2013.06.038
-
Zhang ZR, Bonifacino JS, Hegde RS. 2013. Deubiquitinases sharpen substrate discrimination during membrane protein degradation from the ER. Cell 154:609-622. doi: 10.1016/j.cell.2013.06.038.
-
(2013)
Cell
, vol.154
, pp. 609-622
-
-
Zhang, Z.R.1
Bonifacino, J.S.2
Hegde, R.S.3
-
54
-
-
33747891213
-
Ataxin-3 binds VCP/p97 and regulates retrotranslocation of ERAD substrates
-
doi: 10.1093/hmg/ddl164
-
Zhong X, Pittman RN. 2006. Ataxin-3 binds VCP/p97 and regulates retrotranslocation of ERAD substrates. Human Molecular Genetics 15:2409-2420. doi: 10.1093/hmg/ddl164.
-
(2006)
Human Molecular Genetics
, vol.15
, pp. 2409-2420
-
-
Zhong, X.1
Pittman, R.N.2
-
55
-
-
8544263881
-
AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation
-
doi: 10.1074/jbc.M409034200
-
Zhong X, Shen Y, Ballar P, Apostolou A, Agami R, Fang S. 2004. AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation. The Journal of Biological Chemistry 279:45676-45684. doi: 10.1074/jbc.M409034200.
-
(2004)
The Journal of Biological Chemistry
, vol.279
, pp. 45676-45684
-
-
Zhong, X.1
Shen, Y.2
Ballar, P.3
Apostolou, A.4
Agami, R.5
Fang, S.6
|