-
1
-
-
0035901090
-
Inflammation and cancer: Back to Virchow
-
Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet 2001;357:539-45.
-
(2001)
Lancet
, vol.357
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
2
-
-
33746069082
-
In memoriam of Rudolf Virchow: A historical retrospective including aspects of inflammation, infection and neoplasia
-
Schmidt A, Weber OF. In memoriam of Rudolf Virchow: a historical retrospective including aspects of inflammation, infection and neoplasia. Contrib Microbiol 2006;13:1-15.
-
(2006)
Contrib Microbiol
, vol.13
, pp. 1-15
-
-
Schmidt, A.1
Weber, O.F.2
-
3
-
-
77953485288
-
Profiling in resolving inflammatory exudates identifies novel anti-inflammatory and pro-resolving mediators and signals for termination
-
Norling LV, Serhan CN. Profiling in resolving inflammatory exudates identifies novel anti-inflammatory and pro-resolving mediators and signals for termination. J Intern Med 2010;268:15-24.
-
(2010)
J Intern Med
, vol.268
, pp. 15-24
-
-
Norling, L.V.1
Serhan, C.N.2
-
4
-
-
84955513503
-
Reparative inflammation takes charge of tissue regeneration
-
Karin M, Clevers H. Reparative inflammation takes charge of tissue regeneration. Nature 2016;529:307-15.
-
(2016)
Nature
, vol.529
, pp. 307-315
-
-
Karin, M.1
Clevers, H.2
-
5
-
-
0032112771
-
Nitric oxide and oxygen radicals in infection, inflammation, and cancer
-
Maeda H, Akaike T. Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistry (Mosc) 1998;63:854-65.
-
(1998)
Biochemistry (Mosc)
, vol.63
, pp. 854-865
-
-
Maeda, H.1
Akaike, T.2
-
6
-
-
84865534083
-
Chronic epithelial NF-kappaB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation
-
Shaked H, Hofseth LJ, Chumanevich A, Chumanevich AA, Wang J, Wang Y, et al. Chronic epithelial NF-kappaB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation. Proc Natl Acad Sci USA 2012;109:14007-12.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 14007-14012
-
-
Shaked, H.1
Hofseth, L.J.2
Chumanevich, A.3
Chumanevich, A.A.4
Wang, J.5
Wang, Y.6
-
8
-
-
77950346282
-
Immunity, inflammation, and cancer
-
Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell 2010;140:883-99.
-
(2010)
Cell
, vol.140
, pp. 883-899
-
-
Grivennikov, S.I.1
Greten, F.R.2
Karin, M.3
-
9
-
-
84868613705
-
Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth
-
Grivennikov SI, Wang K, Mucida D, Stewart CA, Schnabl B, Jauch D, et al. Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature 2012;491:254-8.
-
(2012)
Nature
, vol.491
, pp. 254-258
-
-
Grivennikov, S.I.1
Wang, K.2
Mucida, D.3
Stewart, C.A.4
Schnabl, B.5
Jauch, D.6
-
10
-
-
84918535539
-
Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis
-
Wang K, Kim MK, Di Caro G, Wong J, Shalapour S, Wan J, et al. Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis. Immunity 2014;41:1052-63.
-
(2014)
Immunity
, vol.41
, pp. 1052-1063
-
-
Wang, K.1
Kim, M.K.2
Di Caro, G.3
Wong, J.4
Shalapour, S.5
Wan, J.6
-
11
-
-
0019788502
-
The primary and secondary prevention of cancer
-
Spratt JS. The primary and secondary prevention of cancer. J Surg Oncol 1981;18:219-30.
-
(1981)
J Surg Oncol
, vol.18
, pp. 219-230
-
-
Spratt, J.S.1
-
12
-
-
84887410335
-
Beyond aspirin-cancer prevention with statins, metformin and bisphosphonates
-
Gronich N, Rennert G. Beyond aspirin-cancer prevention with statins, metformin and bisphosphonates. Nat Rev Clin Oncol 2013;10:625-42.
-
(2013)
Nat Rev Clin Oncol
, vol.10
, pp. 625-642
-
-
Gronich, N.1
Rennert, G.2
-
13
-
-
84964740709
-
-
World Health Organization Geneva, Swirzerland: WHO Media Centre Available from
-
World Health Organization. Obesity and overweight. Geneva, Swirzerland: WHO Media Centre; 2015. Available from: http://who. int/mediacentre/factsheets/fs311/en/.
-
(2015)
Obesity and Overweight
-
-
-
14
-
-
84924910144
-
Global burden of cancer attributable to high body-mass index in 2012: A population-based study
-
ArnoldM, Pandeya N, Byrnes G, Renehan AG, Stevens GA, Ezzati M, et al. Global burden of cancer attributable to high body-mass index in 2012: a population-based study. Lancet Oncol 2015;16:36-46.
-
(2015)
Lancet Oncol
, vol.16
, pp. 36-46
-
-
Arnold, M.1
Pandeya, N.2
Byrnes, G.3
Renehan, A.G.4
Stevens, G.A.5
Ezzati, M.6
-
15
-
-
33845866857
-
Inflammation and metabolic disorders
-
Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006; 444:860-7.
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
16
-
-
84955268118
-
Obesity and cancer: The oil that feeds the flame
-
Font-Burgada J, Sun B, Karin M. Obesity and cancer: the oil that feeds the flame. Cell Metab 2016;23:48-62.
-
(2016)
Cell Metab
, vol.23
, pp. 48-62
-
-
Font-Burgada, J.1
Sun, B.2
Karin, M.3
-
17
-
-
84904392112
-
Macrophages, immunity, andmetabolic disease
-
McNelis JC, Olefsky JM. Macrophages, immunity, andmetabolic disease. Immunity 2014;41:36-48.
-
(2014)
Immunity
, vol.41
, pp. 36-48
-
-
McNelis, J.C.1
Olefsky, J.M.2
-
18
-
-
74549167737
-
Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression
-
Park EJ, Lee JH, Yu GY, He G, Ali SR, Holzer RG, et al. Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. Cell 2010;140:197-208.
-
(2010)
Cell
, vol.140
, pp. 197-208
-
-
Park, E.J.1
Lee, J.H.2
Yu, G.Y.3
He, G.4
Ali, S.R.5
Holzer, R.G.6
-
19
-
-
74549217325
-
Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation
-
He G, Yu GY, Temkin V, Ogata H, Kuntzen C, Sakurai T, et al. Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation. Cancer Cell 2010;17: 286-97.
-
(2010)
Cancer Cell
, vol.17
, pp. 286-297
-
-
He, G.1
Yu, G.Y.2
Temkin, V.3
Ogata, H.4
Kuntzen, C.5
Sakurai, T.6
-
20
-
-
56749184290
-
Insulin and insulin-like growth factor signalling in neoplasia
-
Pollak M. Insulin and insulin-like growth factor signalling in neoplasia. Nat Rev Cancer 2008;8:915-28.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 915-928
-
-
Pollak, M.1
-
21
-
-
84926148241
-
Obesity as a cause of hepatocellular carcinoma
-
Kew MC. Obesity as a cause of hepatocellular carcinoma. Ann Hepatol 2015;14:299-303.
-
(2015)
Ann Hepatol
, vol.14
, pp. 299-303
-
-
Kew, M.C.1
-
22
-
-
79251479402
-
Diet-induced weight loss reduces colorectal inflammation: Implications for colorectal carcinogenesis
-
Pendyala S, Neff LM, Suarez-Farinas M, Holt PR. Diet-induced weight loss reduces colorectal inflammation: implications for colorectal carcinogenesis. Am J Clin Nutr 2011;93:234-42.
-
(2011)
Am J Clin Nutr
, vol.93
, pp. 234-242
-
-
Pendyala, S.1
Neff, L.M.2
Suarez-Farinas, M.3
Holt, P.R.4
-
23
-
-
84921467844
-
Macrophage recruitment in obese adipose tissue
-
Bai Y, Sun Q. Macrophage recruitment in obese adipose tissue. Obes Rev 2015;16:127-36.
-
(2015)
Obes Rev
, vol.16
, pp. 127-136
-
-
Bai, Y.1
Sun, Q.2
-
24
-
-
67649344115
-
Effects of bariatric surgery on cancer incidence in obese patients in Sweden (Swedish Obese Subjects Study): A prospective, controlled intervention trial
-
Sjostrom L, Gummesson A, Sjostrom CD, Narbro K, Peltonen M, Wedel H, et al. Effects of bariatric surgery on cancer incidence in obese patients in Sweden (Swedish Obese Subjects Study): a prospective, controlled intervention trial. Lancet Oncol 2009;10:653-62.
-
(2009)
Lancet Oncol
, vol.10
, pp. 653-662
-
-
Sjostrom, L.1
Gummesson, A.2
Sjostrom, C.D.3
Narbro, K.4
Peltonen, M.5
Wedel, H.6
-
25
-
-
33746772121
-
Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids
-
Todoric J, Loffler M, Huber J, Bilban M, Reimers M, Kadl A, et al. Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids. Diabetologia 2006;49: 2109-19.
-
(2006)
Diabetologia
, vol.49
, pp. 2109-2119
-
-
Todoric, J.1
Loffler, M.2
Huber, J.3
Bilban, M.4
Reimers, M.5
Kadl, A.6
-
26
-
-
70349639659
-
12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice
-
Sears DD, Miles PD, Chapman J, Ofrecio JM, Almazan F, Thapar D, et al. 12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice. PLoS One 2009;4:e7250.
-
(2009)
PLoS One
, vol.4
, pp. e7250
-
-
Sears, D.D.1
Miles, P.D.2
Chapman, J.3
Ofrecio, J.M.4
Almazan, F.5
Thapar, D.6
-
27
-
-
85008345820
-
-
March 29 Available from
-
Guidelines JDRCD March 29, 2007. Available from: https://www. joslin. org/docs/Nutrition-Guideline-Graded. pdf.
-
(2007)
Guidelines JDRCD
-
-
-
28
-
-
84929735936
-
Prevention of hepatocellular carcinoma by correction of metabolic abnormalities: Role of statins and metformin
-
Ampuero J, Romero-Gomez M. Prevention of hepatocellular carcinoma by correction of metabolic abnormalities: role of statins and metformin. World J Hepatol 2015;7:1105-11.
-
(2015)
World J Hepatol
, vol.7
, pp. 1105-1111
-
-
Ampuero, J.1
Romero-Gomez, M.2
-
29
-
-
60549117324
-
Interaction between tobacco and alcohol use and the risk of head and neck cancer: Pooled analysis in the International Head and Neck Cancer Epidemiology Consortium
-
HashibeM, Brennan P, Chuang SC, Boccia S, Castellsague X, Chen C, et al. Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. Cancer Epidemiol Biomarkers Prev 2009;18: 541-50.
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 541-550
-
-
Hashibe, M.1
Brennan, P.2
Chuang, S.C.3
Boccia, S.4
Castellsague, X.5
Chen, C.6
-
31
-
-
0037132383
-
Alcohol, tobacco and breast cancer-collaborative reanalysis of individual data from 53 epidemiological studies, including 58, 515 women with breast cancer and 95, 067 women without the disease
-
Hamajima N, Hirose K, Tajima K, Rohan T, Calle EE, Heath CW Jr, et al. Alcohol, tobacco and breast cancer-collaborative reanalysis of individual data from 53 epidemiological studies, including 58, 515 women with breast cancer and 95, 067 women without the disease. Br J Cancer 2002;87:1234-45.
-
(2002)
Br J Cancer
, vol.87
, pp. 1234-1245
-
-
Hamajima, N.1
Hirose, K.2
Tajima, K.3
Rohan, T.4
Calle, E.E.5
Heath, C.W.6
-
32
-
-
79954588598
-
Projections of alcohol deaths-a wake-up call
-
Sheron N, Hawkey C, Gilmore I. Projections of alcohol deaths-a wake-up call. Lancet 2011;377:1297-9.
-
(2011)
Lancet
, vol.377
, pp. 1297-1299
-
-
Sheron, N.1
Hawkey, C.2
Gilmore, I.3
-
33
-
-
84867927510
-
Histologic findings in alcoholic liver disease
-
Crawford JM. Histologic findings in alcoholic liver disease. Clin Liver Dis 2012;16:699-716.
-
(2012)
Clin Liver Dis
, vol.16
, pp. 699-716
-
-
Crawford, J.M.1
-
34
-
-
84929301557
-
Liver fibrosis in alcoholic liver disease
-
Bataller R, Gao B. Liver fibrosis in alcoholic liver disease. Semin Liver Dis 2015;35:146-56.
-
(2015)
Semin Liver Dis
, vol.35
, pp. 146-156
-
-
Bataller, R.1
Gao, B.2
-
35
-
-
0026026639
-
Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients
-
Khoruts A, Stahnke L, McClain CJ, Logan G, Allen JI. Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients. Hepatology 1991;13:267-76.
-
(1991)
Hepatology
, vol.13
, pp. 267-276
-
-
Khoruts, A.1
Stahnke, L.2
McClain, C.J.3
Logan, G.4
Allen, J.I.5
-
36
-
-
79953749145
-
The unholy trinity: Inflammation, cytokines, and STAT3 shape the cancer microenvironment
-
Li N, Grivennikov SI, Karin M. The unholy trinity: inflammation, cytokines, and STAT3 shape the cancer microenvironment. Cancer Cell 2011;19:429-31.
-
(2011)
Cancer Cell
, vol.19
, pp. 429-431
-
-
Li, N.1
Grivennikov, S.I.2
Karin, M.3
-
37
-
-
84908665169
-
ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development
-
Nakagawa H, Umemura A, Taniguchi K, Font-Burgada J, Dhar D, Ogata H, et al. ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development. Cancer Cell 2014;26:331-43.
-
(2014)
Cancer Cell
, vol.26
, pp. 331-343
-
-
Nakagawa, H.1
Umemura, A.2
Taniguchi, K.3
Font-Burgada, J.4
Dhar, D.5
Ogata, H.6
-
38
-
-
84863967084
-
EASL clinical practical guidelines: Management of alcoholic liver disease
-
European Association for the Study of L
-
European Association for the Study of L. EASL clinical practical guidelines: management of alcoholic liver disease. J Hepatol 2012;57:399-420.
-
(2012)
J Hepatol
, vol.57
, pp. 399-420
-
-
-
39
-
-
84898824175
-
Interactions between the intestinal microbiome and liver diseases
-
Schnabl B, Brenner DA. Interactions between the intestinal microbiome and liver diseases. Gastroenterology 2014;146:1513-24.
-
(2014)
Gastroenterology
, vol.146
, pp. 1513-1524
-
-
Schnabl, B.1
Brenner, D.A.2
-
40
-
-
67049108920
-
Inflammasome-mediated regulation of hepatic stellate cells
-
Watanabe A, Sohail MA, Gomes DA, Hashmi A, Nagata J, Sutterwala FS, et al. Inflammasome-mediated regulation of hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol 2009;296:G1248-57.
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.296
, pp. G1248-G1257
-
-
Watanabe, A.1
Sohail, M.A.2
Gomes, D.A.3
Hashmi, A.4
Nagata, J.5
Sutterwala, F.S.6
-
41
-
-
46449126460
-
Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: Summary of a symposium
-
Purohit V, Bode JC, Bode C, Brenner DA, Choudhry MA, Hamilton F, et al. Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium. Alcohol 2008; 42:349-61.
-
(2008)
Alcohol
, vol.42
, pp. 349-361
-
-
Purohit, V.1
Bode, J.C.2
Bode, C.3
Brenner, D.A.4
Choudhry, M.A.5
Hamilton, F.6
-
42
-
-
84974783042
-
Ecophysiological consequences of alcoholism on human gut microbiota: Implications for ethanol-related pathogenesis of colon cancer
-
Tsuruya A, Kuwahara A, Saito Y, Yamaguchi H, Tsubo T, Suga S, et al. Ecophysiological consequences of alcoholism on human gut microbiota: implications for ethanol-related pathogenesis of colon cancer. Sci Rep 2016;6:27923.
-
(2016)
Sci Rep
, vol.6
, pp. 27923
-
-
Tsuruya, A.1
Kuwahara, A.2
Saito, Y.3
Yamaguchi, H.4
Tsubo, T.5
Suga, S.6
-
43
-
-
80053925529
-
How the risk of liver cancer changes after alcohol cessation: A review and meta-analysis of the current literature
-
U GG
-
Heckley GA, Jarl J, Asamoah BO, U GG. How the risk of liver cancer changes after alcohol cessation: a review and meta-analysis of the current literature. BMC Cancer 2011;11:446.
-
(2011)
BMC Cancer
, vol.11
, pp. 446
-
-
Heckley, G.A.1
Jarl, J.2
Asamoah, B.O.3
-
44
-
-
84869221496
-
Management of alcohol use disorders in patients with chronic pancreatitis
-
Lang MB, Segersvard R, Grundsten M, Segerdahl M, Arnelo U, Permert J, et al. Management of alcohol use disorders in patients with chronic pancreatitis. JOP 2012;13:654-9.
-
(2012)
JOP
, vol.13
, pp. 654-659
-
-
Lang, M.B.1
Segersvard, R.2
Grundsten, M.3
Segerdahl, M.4
Arnelo, U.5
Permert, J.6
-
45
-
-
83455176701
-
Epidemiology and potential mechanisms of tobacco smoking and heavy alcohol consumption in pancreatic cancer
-
Duell EJ. Epidemiology and potential mechanisms of tobacco smoking and heavy alcohol consumption in pancreatic cancer. Mol Carcinog 2012;51:40-52.
-
(2012)
Mol Carcinog
, vol.51
, pp. 40-52
-
-
Duell, E.J.1
-
46
-
-
84886704004
-
Alcohol exacerbates LPS-induced fibrosis in subclinical acute pancreatitis
-
Gu H, Fortunato F, Bergmann F, Buchler MW, Whitcomb DC, Werner J. Alcohol exacerbates LPS-induced fibrosis in subclinical acute pancreatitis. Am J Pathol 2013;183:1508-17.
-
(2013)
Am J Pathol
, vol.183
, pp. 1508-1517
-
-
Gu, H.1
Fortunato, F.2
Bergmann, F.3
Buchler, M.W.4
Whitcomb, D.C.5
Werner, J.6
-
47
-
-
0031011411
-
Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells
-
Mio T, Romberger DJ, Thompson AB, Robbins RA, Heires A, Rennard SI. Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells. Am J Respir Crit Care Med 1997;155:1770-6.
-
(1997)
Am J Respir Crit Care Med
, vol.155
, pp. 1770-1776
-
-
Mio, T.1
Romberger, D.J.2
Thompson, A.B.3
Robbins, R.A.4
Heires, A.5
Rennard, S.I.6
-
48
-
-
33750949369
-
Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells
-
Kode A, Yang SR, Rahman I. Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells. Respir Res 2006;7:132.
-
(2006)
Respir Res
, vol.7
, pp. 132
-
-
Kode, A.1
Yang, S.R.2
Rahman, I.3
-
49
-
-
44849090900
-
Cigarette smoke increases Toll-like receptor 4 and modifies lipopolysaccharide-mediated responses in airway epithelial cells
-
Pace E, Ferraro M, Siena L, Melis M, Montalbano AM, Johnson M, et al. Cigarette smoke increases Toll-like receptor 4 and modifies lipopolysaccharide-mediated responses in airway epithelial cells. Immunology 2008;124:401-11.
-
(2008)
Immunology
, vol.124
, pp. 401-411
-
-
Pace, E.1
Ferraro, M.2
Siena, L.3
Melis, M.4
Montalbano, A.M.5
Johnson, M.6
-
50
-
-
84863011263
-
Cigarette smoking and inflammation: Cellular and molecular mechanisms
-
Lee J, Taneja V, Vassallo R. Cigarette smoking and inflammation: cellular and molecular mechanisms. J Dent Res 2012;91:142-9.
-
(2012)
J Dent Res
, vol.91
, pp. 142-149
-
-
Lee, J.1
Taneja, V.2
Vassallo, R.3
-
51
-
-
80051612741
-
Receptor for advanced glycation end-products signals through Ras during tobacco smokeinduced pulmonary inflammation
-
Reynolds PR, Kasteler SD, Schmitt RE, Hoidal JR. Receptor for advanced glycation end-products signals through Ras during tobacco smokeinduced pulmonary inflammation. Am J Respir Cell Mol Biol 2011;45: 411-8.
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 411-418
-
-
Reynolds, P.R.1
Kasteler, S.D.2
Schmitt, R.E.3
Hoidal, J.R.4
-
52
-
-
0024376173
-
Ras oncogenes in human cancer: A review
-
Bos JL. ras oncogenes in human cancer: a review. Cancer Res 1989;49: 4682-9.
-
(1989)
Cancer Res
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
53
-
-
27544494856
-
Cigarette smoke activates human monocytes by an oxidant-AP-1 signaling pathway: Implications for steroid resistance
-
Walters MJ, Paul-Clark MJ, McMaster SK, Ito K, Adcock IM, Mitchell JA. Cigarette smoke activates human monocytes by an oxidant-AP-1 signaling pathway: implications for steroid resistance. Mol Pharmacol 2005;68: 1343-53.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 1343-1353
-
-
Walters, M.J.1
Paul-Clark, M.J.2
McMaster, S.K.3
Ito, K.4
Adcock, I.M.5
Mitchell, J.A.6
-
54
-
-
73649112422
-
Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta-and JNK1-dependent inflammation
-
Takahashi H, Ogata H, Nishigaki R, Broide DH, KarinM. Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta-and JNK1-dependent inflammation. Cancer Cell 2010;17:89-97.
-
(2010)
Cancer Cell
, vol.17
, pp. 89-97
-
-
Takahashi, H.1
Ogata, H.2
Nishigaki, R.3
Broide, D.H.4
Karin, M.5
-
55
-
-
0036370334
-
Helicobacter pylori and gastrointestinal tract adenocarcinomas
-
Peek RM Jr, Blaser MJ. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat Rev Cancer 2002;2:28-37.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 28-37
-
-
Peek, R.M.1
Blaser, M.J.2
-
56
-
-
84859812538
-
Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4
-
Dapito DH, Mencin A, Gwak GY, Pradere JP, Jang MK, Mederacke I, et al. Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4. Cancer Cell 2012;21:504-16.
-
(2012)
Cancer Cell
, vol.21
, pp. 504-516
-
-
Dapito, D.H.1
Mencin, A.2
Gwak, G.Y.3
Pradere, J.P.4
Jang, M.K.5
Mederacke, I.6
-
58
-
-
84866372497
-
MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells
-
Ochi A, Nguyen AH, Bedrosian AS, Mushlin HM, Zarbakhsh S, Barilla R, et al. MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells. J Exp Med 2012;209:1671-87.
-
(2012)
J Exp Med
, vol.209
, pp. 1671-1687
-
-
Ochi, A.1
Nguyen, A.H.2
Bedrosian, A.S.3
Mushlin, H.M.4
Zarbakhsh, S.5
Barilla, R.6
-
59
-
-
36549082403
-
Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors
-
Fukata M, Chen A, Vamadevan AS, Cohen J, Breglio K, Krishnareddy S, et al. Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors. Gastroenterology 2007;133:1869-81.
-
(2007)
Gastroenterology
, vol.133
, pp. 1869-1881
-
-
Fukata, M.1
Chen, A.2
Vamadevan, A.S.3
Cohen, J.4
Breglio, K.5
Krishnareddy, S.6
-
60
-
-
84884741548
-
Immune cells: Plastic players along colorectal cancer progression
-
Di Caro G, Marchesi F, Laghi L, Grizzi F. Immune cells: plastic players along colorectal cancer progression. J Cell Mol Med 2013;17:1088-95.
-
(2013)
J Cell Mol Med
, vol.17
, pp. 1088-1095
-
-
Di Caro, G.1
Marchesi, F.2
Laghi, L.3
Grizzi, F.4
-
61
-
-
84878971321
-
Microbiotainduced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer
-
Hu B, Elinav E, Huber S, Strowig T, Hao L, Hafemann A, et al. Microbiotainduced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer. Proc Natl Acad Sci USA 2013;110:9862-7.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 9862-9867
-
-
Hu, B.1
Elinav, E.2
Huber, S.3
Strowig, T.4
Hao, L.5
Hafemann, A.6
-
62
-
-
84867192879
-
Intestinal inflammation targets cancer-inducing activity of the microbiota
-
Arthur JC, Perez-Chanona E, Muhlbauer M, Tomkovich S, Uronis JM, Fan TJ, et al. Intestinal inflammation targets cancer-inducing activity of the microbiota. Science 2012;338:120-3.
-
(2012)
Science
, vol.338
, pp. 120-123
-
-
Arthur, J.C.1
Perez-Chanona, E.2
Muhlbauer, M.3
Tomkovich, S.4
Uronis, J.M.5
Fan, T.J.6
-
63
-
-
84896078883
-
Microbes, microbiota, and colon cancer
-
Sears CL, Garrett WS. Microbes, microbiota, and colon cancer. Cell Host Microbe 2014;15:317-28.
-
(2014)
Cell Host Microbe
, vol.15
, pp. 317-328
-
-
Sears, C.L.1
Garrett, W.S.2
-
64
-
-
84959460952
-
Probiotics, prebiotics and colorectal cancer prevention
-
Ambalam P, Raman M, Purama RK, Doble M. Probiotics, prebiotics and colorectal cancer prevention. Best Pract Res Clin Gastroenterol 2016;30: 119-31.
-
(2016)
Best Pract Res Clin Gastroenterol
, vol.30
, pp. 119-131
-
-
Ambalam, P.1
Raman, M.2
Purama, R.K.3
Doble, M.4
-
66
-
-
33947136322
-
Prebiotics: The concept revisited
-
Roberfroid M. Prebiotics: the concept revisited. J Nutr 2007;137:830S-7S.
-
(2007)
J Nutr
, vol.137
, pp. 830
-
-
Roberfroid, M.1
-
67
-
-
84879447578
-
The interplay between fiber and the intestinal microbiome in the inflammatory response
-
Kuo SM. The interplay between fiber and the intestinal microbiome in the inflammatory response. Adv Nutr 2013;4:16-28.
-
(2013)
Adv Nutr
, vol.4
, pp. 16-28
-
-
Kuo, S.M.1
-
68
-
-
84973866719
-
Exercise-dependent regulation of NK cells in cancer protection
-
Idorn M, Hojman P. Exercise-dependent regulation of NK cells in cancer protection. Trends Mol Med 2016;22:565-77.
-
(2016)
Trends Mol Med
, vol.22
, pp. 565-577
-
-
Idorn, M.1
Hojman, P.2
-
70
-
-
34248141100
-
A cytokine-mediated link between innate immunity, inflammation, and cancer
-
Lin WW, Karin M. A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 2007;117:1175-83.
-
(2007)
J Clin Invest
, vol.117
, pp. 1175
-
-
Lin, W.W.1
Karin, M.2
-
71
-
-
84960808676
-
Voluntary running suppresses tumor growth through epinephrineand IL-6-dependent NK cell mobilization and redistribution
-
Pedersen L, IdornM, Olofsson GH, Lauenborg B, Nookaew I, Hansen RH, et al. Voluntary running suppresses tumor growth through epinephrineand IL-6-dependent NK cell mobilization and redistribution. Cell Metab 2016;23:554-62.
-
(2016)
Cell Metab
, vol.23
, pp. 554-562
-
-
Pedersen, L.1
Idorn, M.2
Olofsson, G.H.3
Lauenborg, B.4
Nookaew, I.5
Hansen, R.H.6
-
72
-
-
78650825618
-
Effect of daily aspirin on long-term risk of death due to cancer: Analysis of individual patient data from randomised trials
-
Rothwell PM, Fowkes FG, Belch JF, Ogawa H, Warlow CP, Meade TW. Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. Lancet 2011; 377:31-41.
-
(2011)
Lancet
, vol.377
, pp. 31-41
-
-
Rothwell, P.M.1
Fowkes, F.G.2
Belch, J.F.3
Ogawa, H.4
Warlow, C.P.5
Meade, T.W.6
-
73
-
-
84973636834
-
The epigenetic effects of aspirin: The modification of histone H3 lysine 27 acetylation in the prevention of colon carcinogenesis in azoxymethane-and dextran sulfate sodium-treated CF-1 mice
-
Guo Y, Liu Y, Zhang C, Su ZY, Li W, Huang MT, et al. The epigenetic effects of aspirin: the modification of histone H3 lysine 27 acetylation in the prevention of colon carcinogenesis in azoxymethane-and dextran sulfate sodium-treated CF-1 mice. Carcinogenesis 2016;37:616-24.
-
(2016)
Carcinogenesis
, vol.37
, pp. 616-624
-
-
Guo, Y.1
Liu, Y.2
Zhang, C.3
Su, Z.Y.4
Li, W.5
Huang, M.T.6
-
74
-
-
82455188359
-
Pharmacology and cellular/molecular mechanisms of action of aspirin and non-aspirin NSAIDs in colorectal cancer
-
Schror K. Pharmacology and cellular/molecular mechanisms of action of aspirin and non-aspirin NSAIDs in colorectal cancer. Best Pract Res Clin Gastroenterol 2011;25:473-84.
-
(2011)
Best Pract Res Clin Gastroenterol
, vol.25
, pp. 473-484
-
-
Schror, K.1
-
75
-
-
84874853682
-
Non-steroid anti-inflammatory drugs, prostaglandins, and cancer
-
Allaj V, Guo C, Nie D. Non-steroid anti-inflammatory drugs, prostaglandins, and cancer. Cell Biosci 2013;3:8.
-
(2013)
Cell Biosci
, vol.3
, pp. 8
-
-
Allaj, V.1
Guo, C.2
Nie, D.3
-
77
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420: 860-7.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
78
-
-
84961615095
-
Virtual dual inhibition of COX-2/5-LOX enzymes based on binding properties of alpha-amyrins, the anti-inflammatory compound as a promising anticancer drug
-
Ranjbar MM, Assadolahi V, Yazdani M, Nikaein D, Rashidieh B. Virtual dual inhibition of COX-2/5-LOX enzymes based on binding properties of alpha-amyrins, the anti-inflammatory compound as a promising anticancer drug. EXCLI J 2016;15:238-45.
-
(2016)
EXCLI J
, vol.15
, pp. 238-245
-
-
Ranjbar, M.M.1
Assadolahi, V.2
Yazdani, M.3
Nikaein, D.4
Rashidieh, B.5
-
79
-
-
80053307147
-
Cardiovascular risk with non-steroidal antiinflammatory drugs: Systematic review of population-based controlled observational studies
-
McGettigan P, Henry D. Cardiovascular risk with non-steroidal antiinflammatory drugs: systematic review of population-based controlled observational studies. PLoS Med 2011;8:e1001098.
-
(2011)
PLoS Med
, vol.8
, pp. e1001098
-
-
McGettigan, P.1
Henry, D.2
-
80
-
-
33745238704
-
Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors
-
GroschS, MaierTJ, SchiffmannS, GeisslingerG. Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors. J Natl Cancer Inst 2006;98:736-47.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 736-747
-
-
Grosch, S.1
Maier, T.J.2
Schiffmann, S.3
Geisslinger, G.4
-
82
-
-
1842428890
-
Pretreatment with dexamethasone increases antitumor activity of carboplatin and gemcitabine in mice bearing human cancer xenografts: In vivo activity, pharmacokinetics, and clinical implications for cancer chemotherapy
-
Wang H, Li M, Rinehart JJ, Zhang R. Pretreatment with dexamethasone increases antitumor activity of carboplatin and gemcitabine in mice bearing human cancer xenografts: in vivo activity, pharmacokinetics, and clinical implications for cancer chemotherapy. Clin Cancer Res 2004;10:1633-44.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1633-1644
-
-
Wang, H.1
Li, M.2
Rinehart, J.J.3
Zhang, R.4
-
83
-
-
12744253457
-
The chemopreventive effects of orally administered dexamethasone in Strain A/Jmice following cessation of smoke exposure
-
WitschiH, Espiritu I, Ly M, UyeminamiD. The chemopreventive effects of orally administered dexamethasone in Strain A/Jmice following cessation of smoke exposure. Inhal Toxicol 2005;17:119-22.
-
(2005)
Inhal Toxicol
, vol.17
, pp. 119-122
-
-
Witschih Espiritu, I.1
Ly, M.2
Uyeminami, D.3
-
84
-
-
84920599743
-
Carfilzomib, lenalidomide, and dexamethasone for relapsed multiple myeloma
-
Stewart AK, Rajkumar SV, Dimopoulos MA, Masszi T, Spicka I, Oriol A, et al. Carfilzomib, lenalidomide, and dexamethasone for relapsed multiple myeloma. N Engl J Med 2015;372:142-52.
-
(2015)
N Engl J Med
, vol.372
, pp. 142-152
-
-
Stewart, A.K.1
Rajkumar, S.V.2
Dimopoulos, M.A.3
Masszi, T.4
Spicka, I.5
Oriol, A.6
-
85
-
-
84952870763
-
The use of corticosteroids in patients with COPD or asthma does not decrease lung squamous cell carcinoma
-
Jian ZH, Huang JY, Lin FC, Nfor ON, Jhang KM, Ku WY, et al. The use of corticosteroids in patients with COPD or asthma does not decrease lung squamous cell carcinoma. BMC Pulm Med 2015;15:154.
-
(2015)
BMC Pulm Med
, vol.15
, pp. 154
-
-
Zh, J.1
Huang, J.Y.2
Lin, F.C.3
Nfor, O.N.4
Jhang, K.M.5
Ku, W.Y.6
-
86
-
-
0035843962
-
Structural mechanism for statin inhibition of HMG-CoA reductase
-
Istvan ES, Deisenhofer J. Structural mechanism for statin inhibition of HMG-CoA reductase. Science 2001;292:1160-4.
-
(2001)
Science
, vol.292
, pp. 1160-1164
-
-
Istvan, E.S.1
Deisenhofer, J.2
-
87
-
-
31844451010
-
Anti-inflammatory effects of statins: Clinical evidence and basic mechanisms
-
JainMK, Ridker PM. Anti-inflammatory effects of statins: clinical evidence and basic mechanisms. Nat Rev Drug Discov 2005;4:977-87.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 977-987
-
-
Jain, M.K.1
Ridker, P.M.2
-
88
-
-
0016928367
-
Reflections from the Dean's office
-
Massey RU. Reflections from the Dean's office. Conn Med 1976;40:212.
-
(1976)
Conn Med
, vol.40
, pp. 212
-
-
Massey, R.U.1
-
89
-
-
2642536741
-
Inflammation immunity, and HMG-CoA reductase inhibitors: Statins as antiinflammatory agents
-
Schonbeck U, Libby P. Inflammation, immunity, and HMG-CoA reductase inhibitors: statins as antiinflammatory agents? Circulation 2004;109: II18-26.
-
(2004)
Circulation
, vol.109
, pp. 1118-1126
-
-
Schonbeck, U.1
Libby, P.2
-
90
-
-
84876516919
-
Statins and the risk of hepatocellular carcinoma in patients with hepatitis C virus infection
-
Tsan YT, Lee CH, Ho WC, Lin MH, Wang JD, Chen PC. Statins and the risk of hepatocellular carcinoma in patients with hepatitis C virus infection. J Clin Oncol 2013;31:1514-21.
-
(2013)
J Clin Oncol
, vol.31
, pp. 1514-1521
-
-
Tsan, Y.T.1
Lee, C.H.2
Ho, W.C.3
Lin, M.H.4
Wang, J.D.5
Chen, P.C.6
-
91
-
-
19444364509
-
Statins and the risk of colorectal cancer
-
Poynter JN, Gruber SB, Higgins PD, Almog R, Bonner JD, Rennert HS, et al. Statins and the risk of colorectal cancer. NEngl JMed 2005;352:2184-92.
-
(2005)
NEngl JMed
, vol.352
, pp. 2184-2192
-
-
Poynter, J.N.1
Gruber, S.B.2
Higgins, P.D.3
Almog, R.4
Bonner, J.D.5
Rennert, H.S.6
-
92
-
-
33644846806
-
Use of statins and breast cancer: A meta-analysis of seven randomized clinical trials and nine observational studies
-
Bonovas S, Filioussi K, Tsavaris N, Sitaras NM. Use of statins and breast cancer: a meta-analysis of seven randomized clinical trials and nine observational studies. J Clin Oncol 2005;23:8606-12.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8606-8612
-
-
Bonovas, S.1
Filioussi, K.2
Tsavaris, N.3
Sitaras, N.M.4
-
93
-
-
84887121545
-
The impact of antiinflammatory agents on the outcome of patients with colorectal cancer
-
Park JH, McMillan DC, Horgan PG, Roxburgh CS. The impact of antiinflammatory agents on the outcome of patients with colorectal cancer. Cancer Treat Rev 2014;40:68-77.
-
(2014)
Cancer Treat Rev
, vol.40
, pp. 68-77
-
-
Park, J.H.1
McMillan, D.C.2
Horgan, P.G.3
Roxburgh, C.S.4
-
94
-
-
84938081688
-
The role of aspirin, Vitamin D, exercise, diet, statins, andmetformin in the prevention and treatment of colorectal cancer
-
Sehdev A, O'Neil BH. The role of aspirin, vitamin D, exercise, diet, statins, andmetformin in the prevention and treatment of colorectal cancer. Curr Treat Options Oncol 2015;16:43.
-
(2015)
Curr Treat Options Oncol
, vol.16
, pp. 43
-
-
Sehdev, A.1
O'Neil, B.H.2
-
96
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
Qian BZ, Pollard JW. Macrophage diversity enhances tumor progression and metastasis. Cell 2010;141:39-51.
-
(2010)
Cell
, vol.141
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
97
-
-
80355146868
-
Monocyte recruitment during infection and inflammation
-
Shi C, Pamer EG. Monocyte recruitment during infection and inflammation. Nat Rev Immunol 2011;11:762-74.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 762-774
-
-
Shi, C.1
Pamer, E.G.2
-
99
-
-
7644231561
-
The chemokine system in diverse forms of macrophage activation and polarization
-
Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 2004;25:677-86.
-
(2004)
Trends Immunol
, vol.25
, pp. 677-686
-
-
Mantovani, A.1
Sica, A.2
Sozzani, S.3
Allavena, P.4
Vecchi, A.5
Locati, M.6
-
100
-
-
84920943285
-
Tumor-associated macrophages as major players in the tumormicroenvironment
-
Chanmee T, Ontong P, Konno K, Itano N. Tumor-associated macrophages as major players in the tumormicroenvironment. Cancers (Basel) 2014;6:1670-90.
-
(2014)
Cancers (Basel)
, vol.6
, pp. 1670-1690
-
-
Chanmee, T.1
Ontong, P.2
Konno, K.3
Itano, N.4
-
101
-
-
0347123433
-
Tumour-educated macrophages promote tumour progression and metastasis
-
Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 2004;4:71-78.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 71-78
-
-
Pollard, J.W.1
-
102
-
-
84904054241
-
Tumour-educated macrophages display amixed polarisation and enhance pancreatic cancer cell invasion
-
Karnevi E, Andersson R, Rosendahl AH. Tumour-educated macrophages display amixed polarisation and enhance pancreatic cancer cell invasion. Immunol Cell Biol 2014;92:543-52.
-
(2014)
Immunol Cell Biol
, vol.92
, pp. 543-552
-
-
Karnevi, E.1
Andersson, R.2
Rosendahl, A.H.3
-
104
-
-
79960411324
-
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
-
Qian BZ, Li J, Zhang H, Kitamura T, Zhang J, Campion LR, et al. CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature 2011;475:222-5.
-
(2011)
Nature
, vol.475
, pp. 222-225
-
-
Qian, B.Z.1
Li, J.2
Zhang, H.3
Kitamura, T.4
Zhang, J.5
Campion, L.R.6
-
105
-
-
84928226005
-
The interaction of anticancer therapies with tumor-associated macrophages
-
Mantovani A, Allavena P. The interaction of anticancer therapies with tumor-associated macrophages. J Exp Med 2015;212:435-45.
-
(2015)
J Exp Med
, vol.212
, pp. 435-445
-
-
Mantovani, A.1
Allavena, P.2
-
106
-
-
84879850236
-
Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: A role for targeting the CCL2/CCR2 axis
-
Sanford DE, Belt BA, Panni RZ, Mayer A, Deshpande AD, Carpenter D, et al. Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: a role for targeting the CCL2/CCR2 axis. Clin Cancer Res 2013;19:3404-15.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 3404-3415
-
-
Sanford, D.E.1
Belt, B.A.2
Panni, R.Z.3
Mayer, A.4
Deshpande, A.D.5
Carpenter, D.6
-
107
-
-
4944244259
-
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
-
Murdoch C, Giannoudis A, Lewis CE. Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues. Blood 2004;104:2224-34.
-
(2004)
Blood
, vol.104
, pp. 2224-2234
-
-
Murdoch, C.1
Giannoudis, A.2
Lewis, C.E.3
-
109
-
-
84962290319
-
Tasquinimod modulates suppressive myeloid cells and enhances cancer immunotherapies in murine models
-
Shen L, Sundstedt A, Ciesielski M, Miles KM, Celander M, Adelaiye R, et al. Tasquinimod modulates suppressive myeloid cells and enhances cancer immunotherapies in murine models. Cancer Immunol Res 2015;3:136-48.
-
(2015)
Cancer Immunol Res
, vol.3
, pp. 136-148
-
-
Shen, L.1
Sundstedt, A.2
Ciesielski, M.3
Miles, K.M.4
Celander, M.5
Adelaiye, R.6
-
110
-
-
84997171030
-
Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment
-
Olsson A, Nakhle J, Sundstedt A, Plas P, Bauchet AL, Pierron V, et al. Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment. J Immunother Cancer 2015;3:53.
-
(2015)
J Immunother Cancer
, vol.3
, pp. 53
-
-
Olsson, A.1
Nakhle, J.2
Sundstedt, A.3
Plas, P.4
Bauchet, A.L.5
Pierron, V.6
-
111
-
-
80052397157
-
COX-2 inhibition alters the phenotype of tumor-associated macrophages fromM2toM1in ApcMin/\+mouse polyps
-
Nakanishi Y, Nakatsuji M, Seno H, Ishizu S, Akitake-Kawano R, Kanda K, et al. COX-2 inhibition alters the phenotype of tumor-associated macrophages fromM2toM1in ApcMin/\+mouse polyps. Carcinogenesis 2011;32:1333-9.
-
(2011)
Carcinogenesis
, vol.32
, pp. 1333-1339
-
-
Nakanishi, Y.1
Nakatsuji, M.2
Seno, H.3
Ishizu, S.4
Akitake-Kawano, R.5
Kanda, K.6
-
112
-
-
68549104285
-
Targeting tumor-associated macrophages in an experimental glioma model with a recombinant immunotoxin to folate receptor beta
-
Nagai T, TanakaM, Tsuneyoshi Y, Xu B, Michie SA, Hasui K, et al. Targeting tumor-associated macrophages in an experimental glioma model with a recombinant immunotoxin to folate receptor beta. Cancer Immunol Immunother 2009;58:1577-86.
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 1577-1586
-
-
Nagai, T.1
Tanakam Tsuneyoshi, Y.2
Xu, B.3
Michie, S.A.4
Hasui, K.5
-
113
-
-
33947574564
-
Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: Modern target but ancient solution
-
Aggarwal BB, Sethi G, Ahn KS, Sandur SK, Pandey MK, Kunnumakkara AB, et al. Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution. AnnN Y Acad Sci 2006;1091:151-69.
-
(2006)
AnnN y Acad Sci
, vol.1091
, pp. 151-169
-
-
Aggarwal, B.B.1
Sethi, G.2
Ahn, K.S.3
Sandur, S.K.4
Pandey, M.K.5
Kunnumakkara, A.B.6
-
114
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 2006;441:431-6.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
115
-
-
80051733032
-
Inhibiting signal transducer and activator of transcription 3: Rationality and rationale design of inhibitors
-
Mankan AK, Greten FR. Inhibiting signal transducer and activator of transcription 3: rationality and rationale design of inhibitors. Expert Opin Investig Drugs 2011;20:1263-75.
-
(2011)
Expert Opin Investig Drugs
, vol.20
, pp. 1263-1275
-
-
Mankan, A.K.1
Greten, F.R.2
-
116
-
-
84896494013
-
IL-6 and related cytokines as the critical lynchpins between inflammation and cancer
-
Taniguchi K, Karin M. IL-6 and related cytokines as the critical lynchpins between inflammation and cancer. Semin Immunol 2014;26:54-74.
-
(2014)
Semin Immunol
, vol.26
, pp. 54-74
-
-
Taniguchi, K.1
Karin, M.2
-
117
-
-
79960346759
-
Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas
-
Pilati C, Amessou M, Bihl MP, Balabaud C, Nhieu JT, Paradis V, et al. Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas. J Exp Med 2011;208:1359-66.
-
(2011)
J Exp Med
, vol.208
, pp. 1359-1366
-
-
Pilati, C.1
Amessou, M.2
Bihl, M.P.3
Balabaud, C.4
Nhieu, J.T.5
Paradis, V.6
-
118
-
-
58649119388
-
Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment
-
KortylewskiM, Xin H, Kujawski M, LeeH, Liu Y, Harris T, et al. Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment. Cancer Cell 2009;15:114-23.
-
(2009)
Cancer Cell
, vol.15
, pp. 114-123
-
-
Kortylewski, M.1
Xin, H.2
Kujawski, M.3
Lee, H.4
Liu, Y.5
Harris, T.6
-
119
-
-
84890780466
-
STAT3 inhibitors for cancer therapy: Have all roads been explored
-
Fagard R, Metelev V, Souissi I, Baran-Marszak F. STAT3 inhibitors for cancer therapy: Have all roads been explored? JAKSTAT 2013;2:e22882.
-
(2013)
JAKSTAT
, vol.2
, pp. e22882
-
-
Fagard, R.1
Metelev, V.2
Souissi, I.3
Baran-Marszak, F.4
-
121
-
-
84861390265
-
Tofacitinib for the treatment of rheumatoid arthritis
-
Zerbini CA, Lomonte AB. Tofacitinib for the treatment of rheumatoid arthritis. Expert Rev Clin Immunol 2012;8:319-31.
-
(2012)
Expert Rev Clin Immunol
, vol.8
, pp. 319-331
-
-
Zerbini, C.A.1
Lomonte, A.B.2
-
122
-
-
84939570937
-
A phase 1 dosing study of ruxolitinib in children with relapsed or refractory solid tumors, leukemias, or myeloproliferative neoplasms: A Children's Oncology Group phase 1 consortium study (ADVL1011)
-
Loh ML, Tasian SK, Rabin KR, Brown P, Magoon D, Reid JM, et al. A phase 1 dosing study of ruxolitinib in children with relapsed or refractory solid tumors, leukemias, or myeloproliferative neoplasms: A Children's Oncology Group phase 1 consortium study (ADVL1011). Pediatr Blood Cancer 2015;62:1717-24.
-
(2015)
Pediatr Blood Cancer
, vol.62
, pp. 1717-1724
-
-
Loh, M.L.1
Tasian, S.K.2
Rabin, K.R.3
Brown, P.4
Magoon, D.5
Reid, J.M.6
-
123
-
-
84880691700
-
AZD1480: A phase i study of a novel JAK2 inhibitor in solid tumors
-
Plimack ER, Lorusso PM, McCoon P, Tang W, Krebs AD, Curt G, et al. AZD1480: a phase I study of a novel JAK2 inhibitor in solid tumors. Oncologist 2013;18:819-20.
-
(2013)
Oncologist
, vol.18
, pp. 819-820
-
-
Plimack, E.R.1
Lorusso, P.M.2
McCoon, P.3
Tang, W.4
Krebs, A.D.5
Curt, G.6
-
125
-
-
84959420149
-
NF-kappaB restricts inflammasome activation via elimination of damaged mitochondria
-
Zhong Z, Umemura A, Sanchez-Lopez E, Liang S, Shalapour S, Wong J, et al. NF-kappaB restricts inflammasome activation via elimination of damaged mitochondria. Cell 2016;164:896-910.
-
(2016)
Cell
, vol.164
, pp. 896-910
-
-
Zhong, Z.1
Umemura, A.2
Sanchez-Lopez, E.3
Liang, S.4
Shalapour, S.5
Wong, J.6
-
126
-
-
78751628117
-
IL-1beta-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKbeta
-
Hsu LC, Enzler T, Seita J, Timmer AM, Lee CY, Lai TY, et al. IL-1beta-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKbeta. Nat Immunol 2011;12:144-50.
-
(2011)
Nat Immunol
, vol.12
, pp. 144-150
-
-
Hsu, L.C.1
Enzler, T.2
Seita, J.3
Timmer, A.M.4
Lee, C.Y.5
Lai, T.Y.6
-
127
-
-
33947197883
-
Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factorkappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells
-
Bhardwaj A, Sethi G, Vadhan-Raj S, Bueso-Ramos C, Takada Y, Gaur U, et al. Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factorkappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. Blood 2007;109:2293-302.
-
(2007)
Blood
, vol.109
, pp. 2293-2302
-
-
Bhardwaj, A.1
Sethi, G.2
Vadhan-Raj, S.3
Bueso-Ramos, C.4
Takada, Y.5
Gaur, U.6
-
128
-
-
0042090509
-
Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: Correlationwith down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1
-
Shishodia S, Majumdar S, Banerjee S, Aggarwal BB. Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: correlationwith down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1. Cancer Res 2003;63:4375-83.
-
(2003)
Cancer Res
, vol.63
, pp. 4375-4383
-
-
Shishodia, S.1
Majumdar, S.2
Banerjee, S.3
Aggarwal, B.B.4
-
129
-
-
0028867742
-
Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]
-
Singh S, Aggarwal BB. Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J Biol Chem 1995;270:24995-5000.
-
(1995)
J Biol Chem
, vol.270
, pp. 24995-25000
-
-
Singh, S.1
Aggarwal, B.B.2
-
130
-
-
84861603829
-
Silibinin modulates lipid homeostasis and inhibits nuclear factor kappa B activation in experimental nonalcoholic steatohepatitis
-
Salamone F, Galvano F, Cappello F, Mangiameli A, Barbagallo I, Li Volti G. Silibinin modulates lipid homeostasis and inhibits nuclear factor kappa B activation in experimental nonalcoholic steatohepatitis. Transl Res 2012;159:477-86.
-
(2012)
Transl Res
, vol.159
, pp. 477-486
-
-
Salamone, F.1
Galvano, F.2
Cappello, F.3
Mangiameli, A.4
Barbagallo, I.5
Li Volti, G.6
-
131
-
-
84865863345
-
Enhanced antitumor effect of combination therapy with gemcitabine and guggulsterone in pancreatic cancer
-
Ahn DW, Seo JK, Lee SH, Hwang JH, Lee JK, Ryu JK, et al. Enhanced antitumor effect of combination therapy with gemcitabine and guggulsterone in pancreatic cancer. Pancreas 2012;41:1048-57.
-
(2012)
Pancreas
, vol.41
, pp. 1048-1057
-
-
Ahn, D.W.1
Seo, J.K.2
Lee, S.H.3
Hwang, J.H.4
Lee, J.K.5
Ryu, J.K.6
-
132
-
-
59449085264
-
Targeting inflammatory pathways for prevention and therapy of cancer: Short-term friend, long-term foe
-
Aggarwal BB, Vijayalekshmi RV, Sung B. Targeting inflammatory pathways for prevention and therapy of cancer: short-term friend, long-term foe. Clin Cancer Res 2009;15:425-30.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 425-430
-
-
Aggarwal, B.B.1
Vijayalekshmi, R.V.2
Sung, B.3
-
133
-
-
84976516826
-
Inflammasomes: Mechanism of assembly, regulation and signalling
-
Broz P, Dixit VM. Inflammasomes: mechanism of assembly, regulation and signalling. Nat Rev Immunol 2016;16:407-20.
-
(2016)
Nat Rev Immunol
, vol.16
, pp. 407-420
-
-
Broz, P.1
Dixit, V.M.2
-
134
-
-
84903599695
-
Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer
-
Guo W, Sun Y, Liu W, Wu X, Guo L, Cai P, et al. Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer. Autophagy 2014;10:972-85.
-
(2014)
Autophagy
, vol.10
, pp. 972-985
-
-
Guo, W.1
Sun, Y.2
Liu, W.3
Wu, X.4
Guo, L.5
Cai, P.6
-
135
-
-
84862807232
-
TLR-induced NF-kappaB activation regulates NLRP3 expression in murine macrophages
-
Qiao Y, Wang P, Qi J, Zhang L, Gao C. TLR-induced NF-kappaB activation regulates NLRP3 expression in murine macrophages. FEBS Lett 2012; 586:1022-6.
-
(2012)
FEBS Lett
, vol.586
, pp. 1022-1026
-
-
Qiao, Y.1
Wang, P.2
Qi, J.3
Zhang, L.4
Gao, C.5
-
136
-
-
84876465900
-
Inflammasome in intestinal inflammation and cancer
-
Nunes T, de Souza HS. Inflammasome in intestinal inflammation and cancer. Mediators Inflamm 2013;2013:654963.
-
(2013)
Mediators Inflamm
, vol.2013
, pp. 654963
-
-
Nunes, T.1
De Souza, H.S.2
-
137
-
-
84946763293
-
Basal autophagy maintains pancreatic acinar cellhomeostasis and protein synthesis and prevents ER stress
-
Antonucci L, Fagman JB, Kim JY, Todoric J, Gukovsky I, Mackey M, et al. Basal autophagy maintains pancreatic acinar cellhomeostasis and protein synthesis and prevents ER stress. Proc Natl Acad Sci USA 2015;112: E6166-74.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. E6166-E6174
-
-
Antonucci, L.1
Fagman, J.B.2
Kim, J.Y.3
Todoric, J.4
Gukovsky, I.5
MacKey, M.6
-
138
-
-
84876789628
-
Loss of acinar cell IKKalpha triggers spontaneous pancreatitis in mice
-
Li N, Wu X, Holzer RG, Lee JH, Todoric J, Park EJ, et al. Loss of acinar cell IKKalpha triggers spontaneous pancreatitis in mice. J Clin Invest 2013;123:2231-43.
-
(2013)
J Clin Invest
, vol.123
, pp. 2231-2243
-
-
Li, N.1
Wu, X.2
Holzer, R.G.3
Lee, J.H.4
Todoric, J.5
Park, E.J.6
-
139
-
-
84863413028
-
Obesity, autophagy and the pathogenesis of liver and pancreatic cancers
-
Aghajan M, Li N, Karin M. Obesity, autophagy and the pathogenesis of liver and pancreatic cancers. J Gastroenterol Hepatol 27 Suppl 2012;2:10-4.
-
(2012)
J Gastroenterol Hepatol
, vol.27
, pp. 10-14
-
-
Aghajan, M.1
Li, N.2
Karin, M.3
-
140
-
-
0041677606
-
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
-
Heinrich PC, Behrmann I, Haan S, Hermanns HM, Muller-Newen G, Schaper F. Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem J 2003;374:1-20.
-
(2003)
Biochem J
, vol.374
, pp. 1-20
-
-
Heinrich, P.C.1
Behrmann, I.2
Haan, S.3
Hermanns, H.M.4
Muller-Newen, G.5
Schaper, F.6
-
141
-
-
84942292465
-
Inflammation and cancer: Advances and new agents
-
Crusz SM, Balkwill FR. Inflammation and cancer: advances and new agents. Nat Rev Clin Oncol 2015;12:584-96.
-
(2015)
Nat Rev Clin Oncol
, vol.12
, pp. 584-596
-
-
Crusz, S.M.1
Balkwill, F.R.2
-
142
-
-
84953344126
-
The IL-23 to IL-17 cascade inflammation-related cancers
-
Wang K, Karin M. The IL-23 to IL-17 cascade inflammation-related cancers. Clin Exp Rheumatol 2015;33:S87-90.
-
(2015)
Clin Exp Rheumatol
, vol.33
, pp. 587-590
-
-
Wang, K.1
Karin, M.2
-
143
-
-
84936891385
-
IL-12 and IL-23 cytokines: From discovery to targeted therapies for immune-mediated inflammatory diseases
-
Teng MW, Bowman EP, McElwee JJ, Smyth MJ, Casanova JL, Cooper AM, et al. IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases. Nat Med 2015;21:719-29.
-
(2015)
Nat Med
, vol.21
, pp. 719-729
-
-
Teng, M.W.1
Bowman, E.P.2
McElwee, J.J.3
Smyth, M.J.4
Casanova, J.L.5
Cooper, A.M.6
-
144
-
-
84892853405
-
Immune therapeutic strategies in chronic hepatitis B virus infection: Virus or inflammation control
-
Bertoletti A, Gehring AJ. Immune therapeutic strategies in chronic hepatitis B virus infection: virus or inflammation control? PLoS Pathog 2013;9:e1003784.
-
(2013)
PLoS Pathog
, vol.9
, pp. 1003784
-
-
Bertoletti, A.1
Gehring, A.J.2
-
145
-
-
0030965103
-
Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children
-
Taiwan Childhood Hepatoma Study Group
-
Chang MH, Chen CJ, Lai MS, Hsu HM, Wu TC, Kong MS, et al. Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group. N Engl J Med 1997;336:1855-59.
-
(1997)
N Engl J Med
, vol.336
, pp. 1855-1859
-
-
Chang, M.H.1
Chen, C.J.2
Lai, M.S.3
Hsu, H.M.4
Wu, T.C.5
Kong, M.S.6
-
146
-
-
84929746938
-
Current and future antiviral drug therapies of hepatitis B chronic infection
-
Koumbi L. Current and future antiviral drug therapies of hepatitis B chronic infection. World J Hepatol 2015;7:1030-40.
-
(2015)
World J Hepatol
, vol.7
, pp. 1030-1040
-
-
Koumbi, L.1
-
147
-
-
84913592791
-
Natural history of hepatitis C
-
Westbrook RH, Dusheiko G. Natural history of hepatitis C. J Hepatol 2014;61:S58-68.
-
(2014)
J Hepatol
, vol.61
, pp. 558-568
-
-
Westbrook, R.H.1
Dusheiko, G.2
-
148
-
-
33644933659
-
The epidemiology of genital human papillomavirus infection
-
Trottier H, Franco EL. The epidemiology of genital human papillomavirus infection. Vaccine 2006;24 Suppl 1:S1-15.
-
(2006)
Vaccine
, vol.24
, pp. 51
-
-
Trottier, H.1
Franco, E.L.2
|