-
1
-
-
79955479172
-
Preventive therapy for breast cancer: A consensus statement
-
Cuzick, J. et al. Preventive therapy for breast cancer: A consensus statement. Lancet Oncol. 12, 496-503 (2011
-
(2011)
Lancet Oncol
, vol.12
, pp. 496-503
-
-
Cuzick, J.1
-
2
-
-
84860386459
-
The role of aspirin in cancer prevention
-
Thun, M. J., Jacobs, E. J. & Patrono, C. The role of aspirin in cancer prevention. Nat. Rev. Clin. Oncol. 9, 259-267 (2012
-
(2012)
Nat. Rev. Clin. Oncol
, vol.9
, pp. 259-267
-
-
Thun, M.J.1
Jacobs, E.J.2
Patrono, C.3
-
3
-
-
65349152488
-
Aspirin and non-steroidal anti inflammatory drugs for cancer prevention: An international consensus statement
-
Cuzick, J. et al. Aspirin and non-steroidal anti inflammatory drugs for cancer prevention: An international consensus statement. Lancet Oncol. 10, 501-507 (2009
-
(2009)
Lancet Oncol
, vol.10
, pp. 501-507
-
-
Cuzick, J.1
-
4
-
-
77951631921
-
A case-control study of levothyroxine and the risk of colorectal cancer
-
Rennert, G., Rennert, H. S., Pinchev, M. & Gruber, S. B. A case-control study of levothyroxine and the risk of colorectal cancer. J. Natl Cancer Inst. 102, 568-572 (2010
-
(2010)
J. Natl Cancer Inst
, vol.102
, pp. 568-572
-
-
Rennert, G.1
Rennert, H.S.2
Pinchev, M.3
Gruber, S.B.4
-
5
-
-
33750049023
-
Colchicine delays the development of hepatocellular carcinoma in patients with hepatitis virus-related liver cirrhosis
-
Arrieta, O. et al. Colchicine delays the development of hepatocellular carcinoma in patients with hepatitis virus-related liver cirrhosis. Cancer 107, 1852-1858 (2006
-
(2006)
Cancer
, vol.107
, pp. 1852-1858
-
-
Arrieta, O.1
-
6
-
-
57749107578
-
Anti-gout agent allopurinol exerts cytotoxicity to human hormone-refractory prostate cancer cells in combination with tumor necrosis factor-related apoptosis-inducing ligand
-
Yasuda, T. et al. Anti-gout agent allopurinol exerts cytotoxicity to human hormone-refractory prostate cancer cells in combination with tumor necrosis factor-related apoptosis-inducing ligand. Mol. Cancer Res. 6, 1852-1860 (2008
-
(2008)
Mol. Cancer Res
, vol.6
, pp. 1852-1860
-
-
Yasuda, T.1
-
7
-
-
84870255289
-
Future directions in cancer prevention
-
Umar, A., Dunn, B. K. & Greenwald, P. Future directions in cancer prevention. Nat. Rev. Cancer 12, 835-848 (2012
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 835-848
-
-
Umar, A.1
Dunn, B.K.2
Greenwald, P.3
-
8
-
-
84880669599
-
Vitamin D supplementation and breast cancer prevention: A systematic review and meta-analysis of randomized clinical trials
-
Sperati, F. et al. Vitamin D supplementation and breast cancer prevention: A systematic review and meta-analysis of randomized clinical trials. PLoS ONE 8, e69269 (2013
-
(2013)
PLoS ONE
, vol.8
-
-
Sperati, F.1
-
9
-
-
85158965676
-
-
Ch eds Waldman, S. A. & Terzic, A Elsevier, Amsterdam
-
Murphy, M. S. & O'Brien, T. in Pharmacology and Therapeutics: Principles to practice Ch. 23 (eds Waldman, S. A. & Terzic, A.) 303-320 (Elsevier, Amsterdam, 2009
-
(2009)
Pharmacology And Therapeutics: Principles To Practice
, vol.23
, pp. 303-320
-
-
Murphy, M.S.1
O'Brien, T.2
-
10
-
-
33645881669
-
Statin safety: A systematic review
-
Law, M. & Rudnicka, A. R. Statin safety: A systematic review. Am. J. Cardiol. 97, 52C-60C (2006
-
(2006)
Am. J. Cardiol
, vol.97
-
-
Law, M.1
Rudnicka, A.R.2
-
11
-
-
83455163746
-
Pharmacological actions of statins: A critical appraisal in the management of cancer
-
Gazzerro, P. et al. Pharmacological actions of statins: A critical appraisal in the management of cancer. Pharmacol. Rev. 64, 102-146 (2012
-
(2012)
Pharmacol. Rev
, vol.64
, pp. 102-146
-
-
Gazzerro, P.1
-
12
-
-
31844451010
-
Anti-inflammatory effects of statins: Clinical evidence and basic mechanisms
-
Jain, M. K. & Ridker, P. M. Anti-inflammatory effects of statins: Clinical evidence and basic mechanisms. Nat. Rev. Drug Discov. 4, 977-987 (2005
-
(2005)
Nat. Rev. Drug Discov
, vol.4
, pp. 977-987
-
-
Jain, M.K.1
Ridker, P.M.2
-
13
-
-
0034533147
-
Statins as a newly recognized type of immunomodulator
-
Kwak, B., Mulhaupt, F., Myit, S. & Mach, F. Statins as a newly recognized type of immunomodulator. Nat. Med. 6, 1399-1402 (2000
-
(2000)
Nat. Med
, vol.6
, pp. 1399-1402
-
-
Kwak, B.1
Mulhaupt, F.2
Myit, S.3
Mach, F.4
-
15
-
-
77956989082
-
Dysregulation of the mevalonate pathway promotes transformation
-
Clendening, J. W. et al. Dysregulation of the mevalonate pathway promotes transformation. Proc. Natl Acad. Sci. USA 107, 15051-15056 (2010
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 15051-15056
-
-
Clendening, J.W.1
-
16
-
-
0031409639
-
Anti-carcinogenic activity of simvastatin during the promotion phase of radiation-induced mammary tumorigenesis of rats
-
Inano, H., Suzuki, K., Onoda, M. & Wakabayashi, K. Anti-carcinogenic activity of simvastatin during the promotion phase of radiation-induced mammary tumorigenesis of rats. Carcinogenesis 18, 1723-1727 (1997
-
(1997)
Carcinogenesis
, vol.18
, pp. 1723-1727
-
-
Inano, H.1
Suzuki, K.2
Onoda, M.3
Wakabayashi, K.4
-
17
-
-
0031784485
-
Reduction of mouse mammary tumor formation and metastasis by lovastatin, an inhibitor of the mevalonate pathway of cholesterol synthesis
-
Alonso, D. F. et al. Reduction of mouse mammary tumor formation and metastasis by lovastatin, an inhibitor of the mevalonate pathway of cholesterol synthesis. Breast Cancer Res. Treat. 50, 83-93 (1998
-
(1998)
Breast Cancer Res. Treat
, vol.50
, pp. 83-93
-
-
Alonso, D.F.1
-
18
-
-
33749040295
-
Breast cancer growth prevention by statins
-
Campbell, M. J. et al. Breast cancer growth prevention by statins. Cancer Res. 66, 8707-8714 (2006
-
(2006)
Cancer Res
, vol.66
, pp. 8707-8714
-
-
Campbell, M.J.1
-
19
-
-
84866767682
-
Immunohistochemical and histomorphological analysis of rat mammary tumors after simvastatin treatment
-
Kubatka, P. et al. Immunohistochemical and histomorphological analysis of rat mammary tumors after simvastatin treatment. Neoplasma 59, 516-523 (2012
-
(2012)
Neoplasma
, vol.59
, pp. 516-523
-
-
Kubatka, P.1
-
20
-
-
54849187000
-
BRCA1 overexpression sensitizes cancer cells to lovastatin via regulation of cyclin D1 CDK4 p21WAF1/CIP1 pathway: Analyses using a breast cancer cell line and tumoral xenograft model
-
Yu, X. et al. BRCA1 overexpression sensitizes cancer cells to lovastatin via regulation of cyclin D1 CDK4 p21WAF1/CIP1 pathway: Analyses using a breast cancer cell line and tumoral xenograft model. Int. J. Oncol. 33, 555-563 (2008
-
(2008)
Int. J. Oncol
, vol.33
, pp. 555-563
-
-
Yu, X.1
-
21
-
-
0030568077
-
Inhibition of lung tumor cell growth in vitro and mouse lung tumor formation by lovastatin
-
Hawk, M. A., Cesen, K. T., Siglin, J. C., Stoner, G. D. & Ruch, R. J. Inhibition of lung tumor cell growth in vitro and mouse lung tumor formation by lovastatin. Cancer Lett. 109, 217-222 (1996
-
(1996)
Cancer Lett
, vol.109
, pp. 217-222
-
-
Hawk, M.A.1
Cesen, K.T.2
Siglin, J.C.3
Stoner, G.D.4
Ruch, R.J.5
-
22
-
-
33746872856
-
Chemoprevention of familial adenomatous polyposis by low doses of atorvastatin and celecoxib given individually and in combination to APCM in mice
-
Swamy, M. V. et al. Chemoprevention of familial adenomatous polyposis by low doses of atorvastatin and celecoxib given individually and in combination to APCM in mice. Cancer Res. 66, 7370-7377 (2006
-
(2006)
Cancer Res
, vol.66
, pp. 7370-7377
-
-
Swamy, M.V.1
-
23
-
-
81555210871
-
Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/β-catenin/cyclin D1 signaling pathway in rats
-
Suh, N. et al. Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/β-catenin/cyclin D1 signaling pathway in rats. Cancer Prev. Res. (Phila.) 4, 1895-1902 (2011
-
(2011)
Cancer Prev. Res. (Phila
, vol.4
, pp. 1895-1902
-
-
Suh, N.1
-
24
-
-
47049103366
-
Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice
-
Cho, S. J. et al. Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice. Int. J. Cancer 123, 951-957 (2008
-
(2008)
Int. J. Cancer
, vol.123
, pp. 951-957
-
-
Cho, S.J.1
-
25
-
-
34548478602
-
The effect of statins in colorectal cancer is mediated through the bone morphogenetic protein pathway
-
Kodach, L. L. et al. The effect of statins in colorectal cancer is mediated through the bone morphogenetic protein pathway. Gastroenterology 133, 1272-1281 (2007
-
(2007)
Gastroenterology
, vol.133
, pp. 1272-1281
-
-
Kodach, L.L.1
-
26
-
-
84865315753
-
Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice
-
Mohammed, A. et al. Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice. Int. J. Cancer 131, 1951-1962 (2012
-
(2012)
Int. J. Cancer
, vol.131
, pp. 1951-1962
-
-
Mohammed, A.1
-
27
-
-
0026671888
-
Inhibition of pancreatic adenocarcinoma cell growth by lovastatin
-
Sumi, S. et al. Inhibition of pancreatic adenocarcinoma cell growth by lovastatin. Gastroenterology 103, 982-989 (1992
-
(1992)
Gastroenterology
, vol.103
, pp. 982-989
-
-
Sumi, S.1
-
28
-
-
39649110600
-
Differences in antitumor effects of various statins on human pancreatic cancer
-
Gbelcová, H. et al. Differences in antitumor effects of various statins on human pancreatic cancer. Int. J. Cancer 122, 1214-1221 (2008
-
(2008)
Int. J. Cancer
, vol.122
, pp. 1214-1221
-
-
Gbelcová, H.1
-
29
-
-
77953731785
-
Lovastatin prevents carcinogenesis in a rat model for liver cancer effects of ubiquinone supplementation
-
Björkhem-Bergman, L., Acimovic, J., Torndal, U. B., Parini, P. & Eriksson, L. C. Lovastatin prevents carcinogenesis in a rat model for liver cancer. Effects of ubiquinone supplementation. Anticancer Res. 30, 1105-1112 (2010
-
(2010)
Anticancer Res
, vol.30
, pp. 1105-1112
-
-
Björkhem-Bergman, L.1
Acimovic, J.2
Torndal, U.B.3
Parini, P.4
Eriksson, L.C.5
-
30
-
-
84865366343
-
The anti-carcinogenic effect of statins in a rat model correlates with levels and synthesis of ubiquinone
-
Acimovic, J., Lövgren-Sandblom, A., Eriksson, L. C. & Björkhem-Bergman, L. The anti-carcinogenic effect of statins in a rat model correlates with levels and synthesis of ubiquinone. Biochem. Biophys. Res. Commun. 425, 348-352 (2012
-
(2012)
Biochem. Biophys. Res. Commun
, vol.425
, pp. 348-352
-
-
Acimovic, J.1
Lövgren-Sandblom, A.2
Eriksson, L.C.3
Björkhem-Bergman, L.4
-
31
-
-
33751523611
-
Pravastatin reduces lung metastasis of rat hepatocellular carcinoma via a coordinated decrease of MMP expression and activity
-
Taras, D. et al. Pravastatin reduces lung metastasis of rat hepatocellular carcinoma via a coordinated decrease of MMP expression and activity. J. Hepatol. 46, 69-76 (2007
-
(2007)
J. Hepatol
, vol.46
, pp. 69-76
-
-
Taras, D.1
-
32
-
-
79952764351
-
MYC phosphorylation, activation, and tumorigenic potential in hepatocellular carcinoma are regulated by HMG-CoA reductase
-
Cao, Z. et al. MYC phosphorylation, activation, and tumorigenic potential in hepatocellular carcinoma are regulated by HMG-CoA reductase. Cancer Res. 71, 2286-2297 (2011
-
(2011)
Cancer Res
, vol.71
, pp. 2286-2297
-
-
Cao, Z.1
-
33
-
-
78650721441
-
Statin-mediated reduction of osteopontin expression induces apoptosis and cell growth arrest in ovarian clear cell carcinoma
-
Matsuura, M. et al. Statin-mediated reduction of osteopontin expression induces apoptosis and cell growth arrest in ovarian clear cell carcinoma. Oncol. Rep. 25, 41-47 (2011
-
(2011)
Oncol. Rep
, vol.25
, pp. 41-47
-
-
Matsuura, M.1
-
34
-
-
78751484981
-
Anticancer efficacy of simvastatin on prostate cancer cells and tumor xenografts is associated with inhibition of akt and reduced prostate-specific antigen expression
-
Kochuparambil, S. T., Al-Husein, B., Goc, A., Soliman, S. & Somanath, P. R. Anticancer efficacy of simvastatin on prostate cancer cells and tumor xenografts is associated with inhibition of Akt and reduced prostate-specific antigen expression. J. Pharmacol. Exp. Ther. 336, 496-505 (2011
-
(2011)
J. Pharmacol. Exp. Ther
, vol.336
, pp. 496-505
-
-
Kochuparambil, S.T.1
Al-Husein, B.2
Goc, A.3
Soliman, S.4
Somanath, P.R.5
-
35
-
-
84865730529
-
A statin-regulated microRNA represses human c myc expression and function
-
Takwi, A. A. et al. A statin-regulated microRNA represses human c Myc expression and function. EMBO Mol. Med. 4, 896-909 (2012
-
(2012)
EMBO Mol. Med
, vol.4
, pp. 896-909
-
-
Takwi, A.A.1
-
36
-
-
77956565365
-
Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled coil containing protein kinase pathway
-
Kidera, Y. et al. Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled coil containing protein kinase pathway. J. Exp. Clin. Cancer Res. 29, 127 (2010
-
(2010)
J. Exp. Clin. Cancer Res
, vol.29
, pp. 127
-
-
Kidera, Y.1
-
37
-
-
0032487931
-
Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels the long-term intervention with pravastatin in ischaemic disease (lipid) study group
-
No Authors Listed
-
.[No authors listed] Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. N. Engl. J. Med. 339, 1349-1357 (1998
-
(1998)
N. Engl. J. Med
, vol.339
, pp. 1349-1357
-
-
-
38
-
-
0037164314
-
Prospective study of pravastatin in the elderly at risk pravastatin in elderly individuals at risk of vascular disease (prosper): A randomised controlled trial
-
Shepherd, J. et al. PROspective Study of Pravastatin in the Elderly at Risk. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): A randomised controlled trial. Lancet 360, 1623-1630 (2002
-
(2002)
Lancet
, vol.360
, pp. 1623-1630
-
-
Shepherd, J.1
-
39
-
-
0035876762
-
Do statins cause cancer? A meta-analysis of large randomized clinical trials
-
Bjerre, L. M. & LeLorier, J. Do statins cause cancer? A meta-analysis of large randomized clinical trials. Am. J. Med. 110, 716-723 (2001
-
(2001)
Am. J. Med
, vol.110
, pp. 716-723
-
-
Bjerre, L.M.1
LeLorier, J.2
-
40
-
-
79952233121
-
Long-term use of cholesterol-lowering drugs and cancer incidence in a large united states cohort
-
Jacobs, E. J., Newton, C. C., Thun, M. J. & Gapstur, S. M. Long-term use of cholesterol-lowering drugs and cancer incidence in a large United States cohort. Cancer Res. 71, 1763-1771 (2011
-
(2011)
Cancer Res
, vol.71
, pp. 1763-1771
-
-
Jacobs, E.J.1
Newton, C.C.2
Thun, M.J.3
Gapstur, S.M.4
-
41
-
-
14844292583
-
Cancer risk among statin users: A population-based cohort study
-
Friis, S. et al. Cancer risk among statin users: A population-based cohort study. Int. J. Cancer 114, 643-647 (2005
-
(2005)
Int. J. Cancer
, vol.114
, pp. 643-647
-
-
Friis, S.1
-
42
-
-
38449120272
-
The association between statins and cancer incidence in a veterans population
-
Farwell, W. R. et al. The association between statins and cancer incidence in a veterans population. J. Natl Cancer Inst. 100, 134-139 (2008
-
(2008)
J. Natl Cancer Inst
, vol.100
, pp. 134-139
-
-
Farwell, W.R.1
-
43
-
-
73449089467
-
Incidence of cancer and statin usage-record linkage study
-
Haukka, J. et al. Incidence of cancer and statin usage-record linkage study. Int. J. Cancer 126, 279-284 (2010
-
(2010)
Int. J. Cancer
, vol.126
, pp. 279-284
-
-
Haukka, J.1
-
44
-
-
84864281063
-
Statins and the risk of cancer after heart transplantation
-
Fröhlich, G. M. et al. Statins and the risk of cancer after heart transplantation. Circulation 126, 440-447 (2012
-
(2012)
Circulation
, vol.126
, pp. 440-447
-
-
Fröhlich, G.M.1
-
45
-
-
84868550230
-
Statin use and reduced cancer related mortality
-
Nielsen, S. F., Nordestgaard, B. G. & Bojesen, S. E. Statin use and reduced cancer related mortality. N. Engl. J. Med. 367, 1792-1802 (2012
-
(2012)
N. Engl. J. Med
, vol.367
, pp. 1792-1802
-
-
Nielsen, S.F.1
Nordestgaard, B.G.2
Bojesen, S.E.3
-
46
-
-
0034726387
-
3 Hydroxy 3-methylglutaryl coenzyme A reductase inhibitors and the risk of cancer: A nested case-control study
-
Blais, L., Desgagné, A. & LeLorier, J. 3 Hydroxy 3-methylglutaryl coenzyme A reductase inhibitors and the risk of cancer: A nested case-control study. Arch. Intern. Med. 160, 2363-2368 (2000
-
(2000)
Arch. Intern. Med
, vol.160
, pp. 2363-2368
-
-
Blais, L.1
Desgagné, A.2
LeLorier, J.3
-
47
-
-
2942754163
-
The risk of cancer in users of statins
-
Graaf, M. R., Beiderbeck, A. B., Egberts, A. C., Richel, D. J. & Guchelaar, H. J. The risk of cancer in users of statins. J. Clin. Oncol. 22, 2388-2394 (2004
-
(2004)
J. Clin. Oncol
, vol.22
, pp. 2388-2394
-
-
Graaf, M.R.1
Beiderbeck, A.B.2
Egberts, A.C.3
Richel, D.J.4
Guchelaar, H.J.5
-
48
-
-
0242363185
-
Lipid-lowering drug use and breast cancer in older women: A prospective study
-
Cauley, J. A. et al. Lipid-lowering drug use and breast cancer in older women: A prospective study. J. Womens Health (Larchmt) 12, 749-756 (2003
-
(2003)
J. Womens Health (Larchmt
, vol.12
, pp. 749-756
-
-
Cauley, J.A.1
-
49
-
-
33646949251
-
Statin use and breast cancer: Prospective results from the women's health initiative
-
Cauley, J. A. et al. Statin use and breast cancer: Prospective results from the Women's Health Initiative. J. Natl Cancer Inst. 98, 700-707 (2006
-
(2006)
J. Natl Cancer Inst
, vol.98
, pp. 700-707
-
-
Cauley, J.A.1
-
50
-
-
43949103427
-
Post-diagnosis statin use and breast cancer recurrence in a prospective cohort study of early stage breast cancer survivors
-
Kwan, M. L., Habel, L. A., Flick, E. D., Quesenberry, C. P. & Caan, B. Post-diagnosis statin use and breast cancer recurrence in a prospective cohort study of early stage breast cancer survivors. Breast Cancer Res. Treat. 109, 573-579 (2008
-
(2008)
Breast Cancer Res. Treat
, vol.109
, pp. 573-579
-
-
Kwan, M.L.1
Habel, L.A.2
Flick, E.D.3
Quesenberry, C.P.4
Caan, B.5
-
51
-
-
80054078528
-
Statin prescriptions and breast cancer recurrence risk: A danish nationwide prospective cohort study
-
Ahern, T. P. et al. Statin prescriptions and breast cancer recurrence risk: A Danish nationwide prospective cohort study. J. Natl Cancer Inst. 103, 1461-1468 (2011
-
(2011)
J. Natl Cancer Inst
, vol.103
, pp. 1461-1468
-
-
Ahern, T.P.1
-
52
-
-
2442687001
-
The association between 3 hydroxy 3-methylglutaryl conenzyme A inhibitor use and breast carcinoma risk among postmenopausal women: A case-control study
-
Boudreau, D. M. et al. The association between 3 hydroxy 3-methylglutaryl conenzyme A inhibitor use and breast carcinoma risk among postmenopausal women: A case-control study. Cancer 100, 2308-2316 (2004
-
(2004)
Cancer
, vol.100
, pp. 2308-2316
-
-
Boudreau, D.M.1
-
53
-
-
81555195415
-
Statin use and colorectal cancer risk according to molecular subtypes in two large prospective cohort studies
-
Lee, J. E. et al. Statin use and colorectal cancer risk according to molecular subtypes in two large prospective cohort studies. Cancer Prev. Res. (Phila.) 4, 1808-1815 (2011
-
(2011)
Cancer Prev. Res. (Phila
, vol.4
, pp. 1808-1815
-
-
Lee, J.E.1
-
54
-
-
83055186553
-
Prospective analysis of association between use of statins or other lipid-lowering agents and colorectal cancer risk
-
Simon, M. S. et al. Prospective analysis of association between use of statins or other lipid-lowering agents and colorectal cancer risk. Ann. Epidemiol. 22, 17-27 (2012
-
(2012)
Ann. Epidemiol
, vol.22
, pp. 17-27
-
-
Simon, M.S.1
-
55
-
-
19444364509
-
Statins and the risk of colorectal cancer
-
Poynter, J. N. et al. Statins and the risk of colorectal cancer. N. Engl. J. Med. 352, 2184-2192 (2005
-
(2005)
N. Engl. J. Med
, vol.352
, pp. 2184-2192
-
-
Poynter, J.N.1
-
56
-
-
79953793170
-
Risk of colorectal cancer in self-reported inflammatory bowel disease and modification of risk by statin and NSAID use
-
Samadder, N. J. et al. Risk of colorectal cancer in self-reported inflammatory bowel disease and modification of risk by statin and NSAID use. Cancer 117, 1640-1648 (2011
-
(2011)
Cancer
, vol.117
, pp. 1640-1648
-
-
Samadder, N.J.1
-
57
-
-
34547499117
-
Risk of colorectal cancer in patients prescribed statins, nonsteroidal anti-inflammatory drugs, and cyclooxygenase 2 inhibitors: Nested case-control study
-
Vinogradova, Y., Hippisley-Cox, J., Coupland, C. & Logan, R. F. Risk of colorectal cancer in patients prescribed statins, nonsteroidal anti-inflammatory drugs, and cyclooxygenase 2 inhibitors: Nested case-control study. Gastroenterology 133, 393-402 (2007
-
(2007)
Gastroenterology
, vol.133
, pp. 393-402
-
-
Vinogradova, Y.1
Hippisley-Cox, J.2
Coupland, C.3
Logan, R.F.4
-
58
-
-
34548096170
-
Individual and joint use of statins and low-dose aspirin and risk of colorectal cancer: A population-based case-control study
-
Hoffmeister, M., Chang-Claude, J. & Brenner, H. Individual and joint use of statins and low-dose aspirin and risk of colorectal cancer: A population-based case-control study. Int. J. Cancer 121, 1325-1330 (2007
-
(2007)
Int. J. Cancer
, vol.121
, pp. 1325-1330
-
-
Hoffmeister, M.1
Chang-Claude, J.2
Brenner, H.3
-
59
-
-
66949119287
-
Statins and the risk of colorectal carcinoma: A nested case-control study in veterans with diabetes
-
Hachem, C., Morgan, R., Johnson, M., Kuebeler, M. & El-Serag, H. Statins and the risk of colorectal carcinoma: A nested case-control study in veterans with diabetes. Am. J. Gastroenterol. 104, 1241-1248 (2009
-
(2009)
Am. J. Gastroenterol
, vol.104
, pp. 1241-1248
-
-
Hachem, C.1
Morgan, R.2
Johnson, M.3
Kuebeler, M.4
El-Serag, H.5
-
60
-
-
78649708483
-
Neither long-term statin use nor atherosclerotic disease is associated with risk of colorectal cancer
-
Robertson, D. J. et al. Neither long-term statin use nor atherosclerotic disease is associated with risk of colorectal cancer. Clin. Gastroenterol. Hepatol. 8, 1056-1061 (2010
-
(2010)
Clin. Gastroenterol. Hepatol
, vol.8
, pp. 1056-1061
-
-
Robertson, D.J.1
-
61
-
-
84862167255
-
Statin use is associated with a reduced incidence of colorectal cancer: A colonoscopy-controlled case-control study
-
Broughton, T., Sington, J. & Beales, I. L. Statin use is associated with a reduced incidence of colorectal cancer: A colonoscopy-controlled case-control study. BMC Gastroenterol. 12, 36 (2012
-
(2012)
BMC Gastroenterol
, vol.12
, pp. 36
-
-
Broughton, T.1
Sington, J.2
Beales, I.L.3
-
62
-
-
84867641427
-
Statin use and association with colorectal cancer survival and risk: Case control study with prescription data linkage
-
Lakha, F. et al. Statin use and association with colorectal cancer survival and risk: Case control study with prescription data linkage. BMC Cancer 12, 487 (2012
-
(2012)
BMC Cancer
, vol.12
, Issue.487
-
-
Lakha, F.1
-
63
-
-
84877876798
-
Statin use is associated with a reduced incidence of colorectal adenomatous polyps
-
Broughton, T., Sington, J. & Beales, I. L. Statin use is associated with a reduced incidence of colorectal adenomatous polyps. Int. J. Colorectal Dis. 28, 469-476 (2013
-
(2013)
Int. J. Colorectal Dis
, vol.28
, pp. 469-476
-
-
Broughton, T.1
Sington, J.2
Beales, I.L.3
-
64
-
-
17744394863
-
Effect of pravastatin on survival in patients with advanced hepatocellular carcinoma a randomized controlled trial
-
Kawata, S. et al. Effect of pravastatin on survival in patients with advanced hepatocellular carcinoma. A randomized controlled trial. Br. J. Cancer 84, 886-891 (2001
-
(2001)
Br. J. Cancer
, vol.84
, pp. 886-891
-
-
Kawata, S.1
-
65
-
-
81855167480
-
Nonsteroidal anti-inflammatory drugs and statins have chemopreventative effects in patients with barrett's esophagus
-
Kastelein, F. et al. Nonsteroidal anti-inflammatory drugs and statins have chemopreventative effects in patients with Barrett's esophagus. Gastroenterology 141, 2000-2008 (2011
-
(2011)
Gastroenterology
, vol.141
, pp. 2000-2008
-
-
Kastelein, F.1
-
66
-
-
84859386286
-
Use of statin medications and risk of esophageal adenocarcinoma in persons with Barrett's esophagus
-
Kantor, E. D., Onstad, L., Blount, P. L., Reid, B. J. & Vaughan, T. L. Use of statin medications and risk of esophageal adenocarcinoma in persons with Barrett's esophagus. Cancer Epidemiol. Biomarkers Prev. 21, 456-461 (2012
-
(2012)
Cancer Epidemiol. Biomarkers Prev
, vol.21
, pp. 456-461
-
-
Kantor, E.D.1
Onstad, L.2
Blount, P.L.3
Reid, B.J.4
Vaughan, T.L.5
-
67
-
-
84856223908
-
Statin use and the risk of renal cell carcinoma in 2 prospective US cohorts
-
Liu, W., Choueiri, T. K. & Cho, E. Statin use and the risk of renal cell carcinoma in 2 prospective US cohorts. Cancer 118, 797-803 (2012
-
(2012)
Cancer
, vol.118
, pp. 797-803
-
-
Liu, W.1
Choueiri, T.K.2
Cho, E.3
-
68
-
-
84863115964
-
Statins and the risk of hepatocellular carcinoma in patients with hepatitis B virus infection
-
Tsan, Y. T., Lee, C. H., Wang, J. D. & Chen, P. C. Statins and the risk of hepatocellular carcinoma in patients with hepatitis B virus infection. J. Clin. Oncol. 30, 623-630 (2012
-
(2012)
J. Clin. Oncol
, vol.30
, pp. 623-630
-
-
Tsan, Y.T.1
Lee, C.H.2
Wang, J.D.3
Chen, P.C.4
-
69
-
-
34248580619
-
Statins reduce the risk of lung cancer in humans: A large case-control study of US veterans
-
Khurana, V., Bejjanki, H. R., Caldito, G. & Owens, M. W. Statins reduce the risk of lung cancer in humans: A large case-control study of US veterans. Chest 131, 1282-1288 (2007
-
(2007)
Chest
, vol.131
, pp. 1282-1288
-
-
Khurana, V.1
Bejjanki, H.R.2
Caldito, G.3
Owens, M.W.4
-
70
-
-
77952837521
-
Medications (nsaids, statins, proton pump inhibitors) and the risk of esophageal adenocarcinoma in patients with barrett's esophagus
-
Nguyen, D. M., Richardson, P. & El-Serag, H. B. Medications (NSAIDs, statins, proton pump inhibitors) and the risk of esophageal adenocarcinoma in patients with Barrett's esophagus. Gastroenterology 138, 2260-2266 (2010
-
(2010)
Gastroenterology
, vol.138
, pp. 2260-2266
-
-
Nguyen, D.M.1
Richardson, P.2
El-Serag, H.B.3
-
71
-
-
84886542274
-
Statin use is associated with a reduction in the incidence of esophageal adenocarcinoma: A case control study
-
Beales, I. L., Vardi, I., Dearman, L. & Broughton, T. Statin use is associated with a reduction in the incidence of esophageal adenocarcinoma: A case control study. Dis. Esophagus http://dx.doi.org/10.1111/j.1442- 2050201201412x.
-
Dis. Esophagus
-
-
Beales, I.L.1
Vardi, I.2
Dearman, L.3
Broughton, T.4
-
72
-
-
82955195805
-
Statins are associated with a reduced risk of gastric cancer: A population-based case-control study
-
Chiu, H. F., Ho, S. C., Chang, C. C., Wu, T. N. & Yang, C. Y. Statins are associated with a reduced risk of gastric cancer: A population-based case-control study. Am. J. Gastroenterol. 106, 2098-2103 (2011
-
(2011)
Am. J. Gastroenterol
, vol.106
, pp. 2098-2103
-
-
Chiu, H.F.1
Ho, S.C.2
Chang, C.C.3
Wu, T.N.4
Yang, C.Y.5
-
73
-
-
33847128808
-
Statins reduce the risk of pancreatic cancer in humans: A case-control study of half a million veterans
-
Khurana, V., Sheth, A., Caldito, G. & Barkin, J. S. Statins reduce the risk of pancreatic cancer in humans: A case-control study of half a million veterans. Pancreas 34, 260-265 (2007
-
(2007)
Pancreas
, vol.34
, pp. 260-265
-
-
Khurana, V.1
Sheth, A.2
Caldito, G.3
Barkin, J.S.4
-
74
-
-
65249190240
-
Statins are associated with a reduced risk of hepatocellular carcinoma in a large cohort of patients with diabetes
-
El-Serag, H. B., Johnson, M. L., Hachem, C. & Morgana, R. O. Statins are associated with a reduced risk of hepatocellular carcinoma in a large cohort of patients with diabetes. Gastroenterology 136, 1601-1608 (2009
-
(2009)
Gastroenterology
, vol.136
, pp. 1601-1608
-
-
El-Serag, H.B.1
Johnson, M.L.2
Hachem, C.3
Morgana, R.O.4
-
75
-
-
79955595053
-
Statin use and the risk of liver cancer: A population-based case-control study
-
Chiu, H. F., Ho, S. C., Chen, C. C. & Yang, C. Y. Statin use and the risk of liver cancer: A population-based case-control study. Am. J. Gastroenterol. 106, 894-898 (2011
-
(2011)
Am. J. Gastroenterol
, vol.106
, pp. 894-898
-
-
Chiu, H.F.1
Ho, S.C.2
Chen, C.C.3
Yang, C.Y.4
-
76
-
-
1542329169
-
Statin use and cancer risk in the general practice research database
-
Kaye, J. A. & Jick, H. Statin use and cancer risk in the General Practice Research Database. Br. J. Cancer 90, 635-637 (2004
-
(2004)
Br. J. Cancer
, vol.90
, pp. 635-637
-
-
Kaye, J.A.1
Jick, H.2
-
77
-
-
33846111227
-
Schneeweiss S statins and the risk of lung, breast, and colorectal cancer in the elderly
-
Setoguchi, S., Glynn, R. J., Avorn, J., Mogun, H. & Schneeweiss, S. Statins and the risk of lung, breast, and colorectal cancer in the elderly. Circulation 115, 27-33 (2007
-
(2007)
Circulation
, vol.115
, pp. 27-33
-
-
Setoguchi, S.1
Glynn, R.J.2
Avorn, J.3
Mogun, H.4
-
78
-
-
58149123594
-
Effect of statins on a wide range of health outcomes: A cohort study validated by comparison with randomized trials
-
Smeeth, L., Douglas, I., Hall, A. J., Hubbard, R. & Evans, S. Effect of statins on a wide range of health outcomes: A cohort study validated by comparison with randomized trials. Br. J. Clin. Pharmacol. 67, 99-109 (2009
-
(2009)
Br. J. Clin. Pharmacol
, vol.67
, pp. 99-109
-
-
Smeeth, L.1
Douglas, I.2
Hall, A.J.3
Hubbard, R.4
Evans, S.5
-
79
-
-
38649095993
-
Screening statins for possible carcinogenic risk: Up to 9 years of follow-up of 361, 859 recipients
-
Friedman, G. D. et al. Screening statins for possible carcinogenic risk: Up to 9 years of follow-up of 361, 859 recipients. Pharmacoepidemiol. Drug Saf. 17, 27-36 (2008
-
(2008)
Pharmacoepidemiol. Drug Saf
, vol.17
, pp. 27-36
-
-
Friedman, G.D.1
-
80
-
-
79960589702
-
Statins and risk of cancer: A retrospective cohort analysis of 45,857 matched pairs from an electronic medical records database of 11 million adult americans
-
Marelli, C. et al. Statins and risk of cancer: A retrospective cohort analysis of 45,857 matched pairs from an electronic medical records database of 11 million adult Americans. J. Am. Coll. Cardiol. 58, 530-537 (2011
-
(2011)
J. Am. Coll. Cardiol
, vol.58
, pp. 530-537
-
-
Marelli, C.1
-
81
-
-
80053367221
-
Exposure to statins and risk of common cancers: A series of nested case-control studies
-
Vinogradova, Y., Coupland, C. & Hippisley-Cox, J. Exposure to statins and risk of common cancers: A series of nested case-control studies. BMC Cancer 11, 409 (2011
-
(2011)
BMC Cancer
, vol.11
, Issue.409
-
-
Vinogradova, Y.1
Coupland, C.2
Hippisley-Cox, J.3
-
82
-
-
34047253021
-
Statin use and breast cancer risk in a large population-based setting
-
Boudreau, D. M., Yu, O., Miglioretti, D. L., Buist, D. S., Heckbert, S. R. & Daling, J. R. Statin use and breast cancer risk in a large population-based setting. Cancer Epidemiol. Biomarkers Prev. 16, 416-421 (2007
-
(2007)
Cancer Epidemiol. Biomarkers Prev
, vol.16
, pp. 416-421
-
-
Boudreau, D.M.1
Yu, O.2
Miglioretti, D.L.3
Buist, D.S.4
Heckbert, S.R.5
Daling, J.R.6
-
83
-
-
0037029714
-
Statin use, hyperlipidaemia, and the risk of breast cancer
-
Kaye, J. A., Meier, C. R., Walker, A. M. & Jick, H. Statin use, hyperlipidaemia, and the risk of breast cancer. Br. J. Cancer 86, 1436-1439 (2002
-
(2002)
Br. J. Cancer
, vol.86
, pp. 1436-1439
-
-
Kaye, J.A.1
Meier, C.R.2
Walker, A.M.3
Jick, H.4
-
84
-
-
77958048332
-
Lipophilic statin use and risk of breast cancer subtypes
-
Woditschka, S., Habel, L. A., Udaltsova, N., Friedman, G. D. & Sieh, W. Lipophilic statin use and risk of breast cancer subtypes. Cancer Epidemiol. Biomarkers Prev. 19, 2479-2487 (2010
-
(2010)
Cancer Epidemiol. Biomarkers Prev
, vol.19
, pp. 2479-2487
-
-
Woditschka, S.1
Habel, L.A.2
Udaltsova, N.3
Friedman, G.D.4
Sieh, W.5
-
85
-
-
30344441524
-
Cholesterol-lowering drugs and colorectal cancer incidence in a large united states cohort
-
Jacobs, E. J. et al. Cholesterol-lowering drugs and colorectal cancer incidence in a large United States cohort. J. Natl Cancer Inst. 98, 69-72 (2006
-
(2006)
J. Natl Cancer Inst
, vol.98
, pp. 69-72
-
-
Jacobs, E.J.1
-
86
-
-
80052956941
-
Relationship between statin use and colon cancer recurrence and survival: Results from calgb 89803
-
Ng, K. et al. Relationship between statin use and colon cancer recurrence and survival: Results from CALGB 89803. J. Natl Cancer Inst. 103, 1540-1551 (2011
-
(2011)
J. Natl Cancer Inst
, vol.103
, pp. 1540-1551
-
-
Ng, K.1
-
87
-
-
77952071890
-
Statin use and colorectal adenoma risk: Results from the adenoma prevention with celecoxib trial
-
Bertagnolli, M. M. et al. Statin use and colorectal adenoma risk: Results from the adenoma prevention with celecoxib trial. Cancer Prev. Res. (Phila.) 3, 588-596 (2010
-
(2010)
Cancer Prev. Res. (Phila
, vol.3
, pp. 588-596
-
-
Bertagnolli, M.M.1
-
88
-
-
33846973669
-
Statin use and risk of colorectal cancer
-
Coogan, P. F., Smith, J. & Rosenberg, L. Statin use and risk of colorectal cancer. J. Natl Cancer Inst. 99, 32-40 (2007
-
(2007)
J. Natl Cancer Inst
, vol.99
, pp. 32-40
-
-
Coogan, P.F.1
Smith, J.2
Rosenberg, L.3
-
89
-
-
52949112234
-
Chronic statin therapy and the risk of colorectal cancer pharmacoepidemiol
-
Yang, Y. X. et al. Chronic statin therapy and the risk of colorectal cancer. Pharmacoepidemiol. Drug Saf. 17, 869-876 (2008
-
(2008)
Drug Saf
, vol.17
, pp. 869-876
-
-
Yang, Y.X.1
-
90
-
-
83755228779
-
Statin use and the risk of colorectal cancer: A population-based case-control study
-
Cheng, M. H. et al. Statin use and the risk of colorectal cancer: A population-based case-control study. World J. Gastroenterol. 17, 5197-5202 (2011
-
(2011)
World J. Gastroenterol
, vol.17
, pp. 5197-5202
-
-
Cheng, M.H.1
-
91
-
-
78751572934
-
Statins and pancreatic cancer risk: A nested case-control study
-
Bradley, M. C., Hughes, C. M., Cantwell, M. M. & Murray, L. J. Statins and pancreatic cancer risk: A nested case-control study. Cancer Causes Control 21, 2093-2100 (2010
-
(2010)
Cancer Causes Control
, vol.21
, pp. 2093-2100
-
-
Bradley, M.C.1
Hughes, C.M.2
Cantwell, M.M.3
Murray, L.J.4
-
92
-
-
67349221748
-
Statin use and female reproductive organ cancer risk in a large population-based setting
-
Yu, O., Boudreau, D. M., Buist, D. S. & Miglioretti, D. L. Statin use and female reproductive organ cancer risk in a large population-based setting. Cancer Causes Control 20, 609-616 (2009
-
(2009)
Cancer Causes Control
, vol.20
, pp. 609-616
-
-
Yu, O.1
Boudreau, D.M.2
Buist, D.S.3
Miglioretti, D.L.4
-
93
-
-
0342981862
-
The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels cholesterol and recurrent events trial investigators
-
Sacks, F. M. et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators. N. Engl. J. Med. 335, 1001-1009 (1996
-
(1996)
N. Engl. J. Med
, vol.335
, pp. 1001-1009
-
-
Sacks, F.M.1
-
94
-
-
0037132607
-
Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (allhat-llt)
-
ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group
-
ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT). JAMA 288, 2998-3007 (2002
-
(2002)
JAMA
, vol.288
, pp. 2998-3007
-
-
-
95
-
-
0033914187
-
Follow-up study of patients randomized in the Scandinavian simvastatin survival study (4S) of cholesterol lowering
-
Pedersen, T. R. et al. Follow-up study of patients randomized in the Scandinavian simvastatin survival study (4S) of cholesterol lowering. Am. J. Cardiol. 86, 257-262 (2000
-
(2000)
Am. J. Cardiol
, vol.86
, pp. 257-262
-
-
Pedersen, T.R.1
-
96
-
-
4444252160
-
Mortality and incidence of cancer during 10-year follow-up of the scandinavian simvastatin survival study (4s
-
Strandberg, T. E. et al. Mortality and incidence of cancer during 10-year follow-up of the Scandinavian Simvastatin Survival Study (4S). Lancet 364, 771-777 (2004
-
(2004)
Lancet
, vol.364
, pp. 771-777
-
-
Strandberg, T.E.1
-
97
-
-
83255193890
-
Effects on 11-year mortality and morbidity of lowering LDL cholesterol with simvastatin for about 5 years in 20,536 high-risk individuals: A randomised controlled trial
-
Bulbulia, R. et al. Effects on 11-year mortality and morbidity of lowering LDL cholesterol with simvastatin for about 5 years in 20,536 high-risk individuals: A randomised controlled trial. Lancet 378, 2013-2020 (2011
-
(2011)
Lancet
, vol.378
, pp. 2013-2020
-
-
Bulbulia, R.1
-
98
-
-
79951576682
-
Time-window bias in case-control studies: Statins and lung cancer
-
Suissa, S., Dell'aniello, S., Vahey, S. & Renoux, C. Time-window bias in case-control studies: Statins and lung cancer. Epidemiology 22, 228-231 (2011
-
(2011)
Epidemiology
, vol.22
, pp. 228-231
-
-
Suissa, S.1
Dell'aniello, S.2
Vahey, S.3
Renoux, C.4
-
99
-
-
14944372177
-
Up-regulation of 3 hydroxy 3-methylglutaryl coenzyme A reductase activity in left-sided human colon cancer
-
Notarnicola, M. et al. Up-regulation of 3 hydroxy 3-methylglutaryl coenzyme A reductase activity in left-sided human colon cancer. Anticancer Res. 24, 3837-3842 (2004
-
(2004)
Anticancer Res
, vol.24
, pp. 3837-3842
-
-
Notarnicola, M.1
-
100
-
-
79951680463
-
Prostate cancer gene expression signature of patients with high body mass index
-
Sharad, S. et al. Prostate cancer gene expression signature of patients with high body mass index. Prostate Cancer Prostatic Dis. 14, 22-29 (2011
-
(2011)
Prostate Cancer Prostatic Dis
, vol.14
, pp. 22-29
-
-
Sharad, S.1
-
101
-
-
84856235374
-
A short-term biomarker modulation study of simvastatin in women at increased risk of a new breast cancer
-
Higgins, M. J. et al. A short-term biomarker modulation study of simvastatin in women at increased risk of a new breast cancer. Breast Cancer Res. Treat. 131, 915-924 (2012
-
(2012)
Breast Cancer Res. Treat
, vol.131
, pp. 915-924
-
-
Higgins, M.J.1
-
102
-
-
29944446607
-
Statins and cancer risk: A meta-analysis
-
Dale, K. M., Coleman, C. I., Henyan, N. N., Kluger, J. & White, C. M. Statins and cancer risk: A meta-analysis. JAMA 295, 74-80 (2006
-
(2006)
JAMA
, vol.295
, pp. 74-80
-
-
Dale, K.M.1
Coleman, C.I.2
Henyan, N.N.3
Kluger, J.4
White, C.M.5
-
103
-
-
54849131100
-
Statins and cancer: A systematic review and meta-analysis
-
Kuoppala, J., Lamminpää, A. & Pukkala, E. Statins and cancer: A systematic review and meta-analysis. Eur. J. Cancer 44, 2122-2132 (2008
-
(2008)
Eur. J. Cancer
, vol.44
, pp. 2122-2132
-
-
Kuoppala, J.1
Lamminpää, A.2
Pukkala, E.3
-
104
-
-
42249096112
-
Statins and cancer: A meta-analysis of case-control studies
-
Taylor, M. L., Wells, B. J. & Smolak, M. J. Statins and cancer: A meta-analysis of case-control studies. Eur. J. Cancer Prev. 17, 259-268 (2008
-
(2008)
Eur. J. Cancer Prev
, vol.17
, pp. 259-268
-
-
Taylor, M.L.1
Wells, B.J.2
Smolak, M.J.3
-
105
-
-
34548019063
-
Statins and the risk of colorectal cancer: A meta-analysis of 18 studies involving more than 1.5 million patients
-
Bonovas, S., Filioussi, K., Flordellis, C. S. & Sitaras, N. M. Statins and the risk of colorectal cancer: A meta-analysis of 18 studies involving more than 1.5 million patients. J. Clin. Oncol. 25, 3462-3468 (2007
-
(2007)
J. Clin. Oncol
, vol.25
, pp. 3462-3468
-
-
Bonovas, S.1
Filioussi, K.2
Flordellis, C.S.3
Sitaras, N.M.4
-
106
-
-
84862492891
-
Statin use and risk of pancreatic cancer: A meta-analysis
-
Cui, X. et al. Statin use and risk of pancreatic cancer: A meta-analysis. Cancer Causes Control 23, 1099-1111 (2012
-
(2012)
Cancer Causes Control
, vol.23
, pp. 1099-1111
-
-
Cui, X.1
-
107
-
-
84881491358
-
Statins are associated with a reduced risk of hepatocellular cancer: A systematic review and meta-analysis
-
Singh, S., Singh, P. P., Singh, A. G., Murad, M. H. & Sanchez, W. Statins are associated with a reduced risk of hepatocellular cancer: A systematic review and meta-analysis. Gastroenterology 144, 323-332 (2013
-
(2013)
Gastroenterology
, vol.144
, pp. 323-332
-
-
Singh, S.1
Singh, P.P.2
Singh, A.G.3
Murad, M.H.4
Sanchez, W.5
-
108
-
-
84861726854
-
-
ClinicalTrials.gov[online
-
US National Library of Medicine. ClinicalTrials.gov[online], http://clinicaltrials.gov/ct2/show/NCT01011478 (2012
-
(2012)
US National Library Of Medicine
-
-
-
109
-
-
84861726854
-
-
ClinicalTrials.gov[online
-
US National Library of Medicine. ClinicalTrials.gov[online], http://clinicaltrials.gov/ct2/show/NCT00816244 (2012
-
(2012)
US National Library Of Medicine
-
-
-
110
-
-
84861726854
-
-
ClinicalTrials.gov[online
-
US National Library of Medicine. ClinicalTrials.gov[online], http://clinicaltrials.gov/ct2/show/study/NCT00637481 (2013
-
(2013)
US National Library Of Medicine
-
-
-
111
-
-
84881100168
-
Statins in the primary prevention of cardiovascular disease
-
Reiner, Z. Statins in the primary prevention of cardiovascular disease. Nat. Rev. Cardiol. 10, 453-464 (2013
-
(2013)
Nat. Rev. Cardiol
, vol.10
, pp. 453-464
-
-
Reiner, Z.1
-
112
-
-
77950813460
-
Genetic variation in 3 hydroxy 3-methylglutaryl coa reductase modifies the chemopreventive activity of statins for colorectal cancer
-
Lipkin, S. M. et al. Genetic variation in 3 hydroxy 3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer. Cancer Prev. Res. (Phila.) 3, 597-603 (2010
-
(2010)
Cancer Prev. Res. (Phila
, vol.3
, pp. 597-603
-
-
Lipkin, S.M.1
-
113
-
-
77955857999
-
Hepatic metabolism and transporter gene variants enhance response to rosuvastatin in patients with acute myocardial infarction: The geostat 1 study
-
Bailey, K. M. et al. Hepatic metabolism and transporter gene variants enhance response to rosuvastatin in patients with acute myocardial infarction: The GEOSTAT 1 Study. Circ. Cardiovasc. Genet. 3, 276-285 (2010
-
(2010)
Circ. Cardiovasc. Genet
, vol.3
, pp. 276-285
-
-
Bailey, K.M.1
-
114
-
-
82955247614
-
Variants in the APOA5 gene region and the response to combination therapy with statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia
-
Brautbar, A. et al. Variants in the APOA5 gene region and the response to combination therapy with statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia. Atherosclerosis 219, 737-742 (2011
-
(2011)
Atherosclerosis
, vol.219
, pp. 737-742
-
-
Brautbar, A.1
-
115
-
-
77955631252
-
Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction
-
Peters, B. J. et al. Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction. Pharmacogenomics 11, 1065-1076 (2010
-
(2010)
Pharmacogenomics
, vol.11
, pp. 1065-1076
-
-
Peters, B.J.1
-
116
-
-
84860798384
-
Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: The justification for the use of statins in prevention: An intervention trial evaluating rosuvastatin (jupiter) trial
-
Chasman, D. I. et al. Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: The Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) trial. Circ. Cardiovasc. Genet. 5, 257-264 (2012
-
(2012)
Circ. Cardiovasc. Genet
, vol.5
, pp. 257-264
-
-
Chasman, D.I.1
-
117
-
-
84862908644
-
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway
-
Freed-Pastor, W. A. et al. Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. Cell 148, 244-258 (2012
-
(2012)
Cell
, vol.148
, pp. 244-258
-
-
Freed-Pastor, W.A.1
-
118
-
-
77956306344
-
Clinical genetics of hereditary colorectal cancer
-
Power, D. G., Gloglowski, E. & Lipkin, S. M. Clinical genetics of hereditary colorectal cancer. Hematol. Oncol. Clin. North Am. 24, 837-859 (2010
-
(2010)
Hematol. Oncol. Clin. North Am.
, vol.24
, pp. 837-859
-
-
Power, D.G.1
Gloglowski, E.2
Lipkin, S.M.3
-
119
-
-
84887408025
-
-
Ch eds Waldman, S. A. & Terzic, A Elsevier, Amsterdam
-
Rizza, R. A. & Vella, A. in Pharmacology and Therapeutics: Principles to practice Ch. 37 (eds Waldman, S. A. & Terzic, A.) 557-570 (Elsevier, Amsterdam, 2009
-
(2009)
Pharmacology And Therapeutics: Principles To Practice
, vol.37
, pp. 557-570
-
-
Rizza, R.A.1
Vella, A.2
-
120
-
-
33644864125
-
Insulin enhances growth hormone induction of the MEK/ERK signaling pathway
-
Xu, J. et al. Insulin enhances growth hormone induction of the MEK/ERK signaling pathway. J. Biol. Chem. 281, 982-992 (2006
-
(2006)
J. Biol. Chem
, vol.281
, pp. 982-992
-
-
Xu, J.1
-
121
-
-
40349098110
-
Insulin regulation of growth hormone receptor gene expression: Involvement of both the PI 3 kinase and MEK/ERK signaling pathways
-
Bennett, W. L., Keeton, A. B., Ji, S., Xu, J. & Messina, J. L. Insulin regulation of growth hormone receptor gene expression: Involvement of both the PI 3 kinase and MEK/ERK signaling pathways. Endocrine 32, 219-226 (2007
-
(2007)
Endocrine
, vol.32
, pp. 219-226
-
-
Bennett, W.L.1
Keeton, A.B.2
Ji, S.3
Xu, J.4
Messina, J.L.5
-
122
-
-
84867177612
-
Plasma proneurotensin and incidence of diabetes, cardiovascular disease, breast cancer, and mortality
-
Melander, O. et al. Plasma proneurotensin and incidence of diabetes, cardiovascular disease, breast cancer, and mortality. JAMA 308, 1469-1475 (2012
-
(2012)
JAMA
, vol.308
, pp. 1469-1475
-
-
Melander, O.1
-
123
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou, G. et al. Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest. 108, 1167-1174 (2001
-
(2001)
J. Clin. Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
-
124
-
-
28844433635
-
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
-
Shaw, R. J. et al. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 310, 1642-1646 (2005
-
(2005)
Science
, vol.310
, pp. 1642-1646
-
-
Shaw, R.J.1
-
125
-
-
0032495530
-
A serine/threonine kinase gene defective in peutz-jeghers syndrome
-
Hemminki, A. et al. A serine/threonine kinase gene defective in Peutz-Jeghers syndrome. Nature 391, 184-187 (1998
-
(1998)
Nature
, vol.391
, pp. 184-187
-
-
Hemminki, A.1
-
126
-
-
33751284806
-
Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells
-
Zakikhani, M., Dowling, R., Fantus, I. G., Sonenberg, N. & Pollak, M. Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells. Cancer Res. 66, 10269-10273 (2006
-
(2006)
Cancer Res
, vol.66
, pp. 10269-10273
-
-
Zakikhani, M.1
Dowling, R.2
Fantus, I.G.3
Sonenberg, N.4
Pollak, M.5
-
127
-
-
61449113987
-
The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase
-
Zakikhani, M., Dowling, R. J., Sonenberg, N. & Pollak, M. N. The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase. Cancer Prev. Res. (Phila.) 1, 369-375 (2008
-
(2008)
Cancer Prev. Res. (Phila
, vol.1
, pp. 369-375
-
-
Zakikhani, M.1
Dowling, R.J.2
Sonenberg, N.3
Pollak, M.N.4
-
128
-
-
79959764729
-
Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1
-
Ben Sahra, I. et al. Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1. Cancer Res. 71, 4366-4372 (2011
-
(2011)
Cancer Res
, vol.71
, pp. 4366-4372
-
-
Ben Sahra, I.1
-
129
-
-
84862908866
-
Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple-negative breast cancers
-
Deng, X. S. et al. Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple-negative breast cancers. Cell Cycle 11, 367-376 (2012
-
(2012)
Cell Cycle
, vol.11
, pp. 367-376
-
-
Deng, X.S.1
-
130
-
-
66849093704
-
Genome-wide inhibitory impact of the AMPK activator metformin on[kinesins, tubulins, histones, auroras and polo-like kinases M phase cell cycle genes in human breast cancer cells
-
Oliveras-Ferraros, C., Vazquez-Martin, A. & Menendez, J. A. Genome-wide inhibitory impact of the AMPK activator metformin on[kinesins, tubulins, histones, auroras and polo-like kinases] M phase cell cycle genes in human breast cancer cells. Cell Cycle 8, 1633-1636 (2009
-
(2009)
Cell Cycle
, vol.8
, pp. 1633-1636
-
-
Oliveras-Ferraros, C.1
Vazquez-Martin, A.2
Menendez, J.A.3
-
131
-
-
84858729494
-
Metformin lowers the threshold for stress-induced senescence: A role for the microRNA 200 family and miR 205
-
Cufí, S. et al. Metformin lowers the threshold for stress-induced senescence: A role for the microRNA 200 family and miR 205. Cell Cycle 11, 1235-1246 (2012
-
(2012)
Cell Cycle
, vol.11
, pp. 1235-1246
-
-
Cufí, S.1
-
132
-
-
79955980904
-
Metformin induces both caspase-dependent and poly(ADP-ribose) polymerase-dependent cell death in breast cancer cells
-
Zhuang, Y. & Miskimins, W. K. Metformin induces both caspase-dependent and poly(ADP-ribose) polymerase-dependent cell death in breast cancer cells. Mol. Cancer Res. 9, 603-615 (2011
-
(2011)
Mol. Cancer Res
, vol.9
, pp. 603-615
-
-
Zhuang, Y.1
Miskimins, W.K.2
-
133
-
-
70350236538
-
Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission
-
Hirsch, H. A., Iliopoulos, D., Tsichlis, P. N. & Struhl, K. Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Res. 69, 7507-7511 (2009
-
(2009)
Cancer Res
, vol.69
, pp. 7507-7511
-
-
Hirsch, H.A.1
Iliopoulos, D.2
Tsichlis, P.N.3
Struhl, K.4
-
134
-
-
79953645921
-
Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: Induction of the tumor suppressor miRNA let-7a and suppression of the TGFβ-induced oncomiR miRNA 181a
-
Oliveras-Ferraros, C. et al. Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: Induction of the tumor suppressor miRNA let-7a and suppression of the TGFβ-induced oncomiR miRNA 181a. Cell Cycle 10, 1144-1151 (2011
-
(2011)
Cell Cycle
, vol.10
, pp. 1144-1151
-
-
Oliveras-Ferraros, C.1
-
135
-
-
34547114031
-
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth
-
Buzzai, M. et al. Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth. Cancer Res. 67, 6745-6752 (2007
-
(2007)
Cancer Res
, vol.67
, pp. 6745-6752
-
-
Buzzai, M.1
-
136
-
-
77956415337
-
Metformin prevents tobacco carcinogen-induced lung tumorigenesis
-
Memmott, R. M. et al. Metformin prevents tobacco carcinogen-induced lung tumorigenesis. Cancer Prev. Res. (Phila.) 3, 1066-1076 (2010
-
(2010)
Cancer Prev. Res. (Phila
, vol.3
, pp. 1066-1076
-
-
Memmott, R.M.1
-
137
-
-
53849118108
-
Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth
-
Algire, C., Zakikhani, M., Blouin, M. J., Shuai, J. H. & Pollak, M. Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth. Endocr. Relat. Cancer 15, 833-839 (2008
-
(2008)
Endocr. Relat. Cancer
, vol.15
, pp. 833-839
-
-
Algire, C.1
Zakikhani, M.2
Blouin, M.J.3
Shuai, J.H.4
Pollak, M.5
-
138
-
-
0035082644
-
Prevention of pancreatic cancer induction in hamsters by metformin
-
Schneider, M. B. et al. Prevention of pancreatic cancer induction in hamsters by metformin. Gastroenterology 120, 1263-1270 (2001
-
(2001)
Gastroenterology
, vol.120
, pp. 1263-1270
-
-
Schneider, M.B.1
-
139
-
-
84865798995
-
Metformin elicits anticancer effects through the sequential modulation of DICER and c MYC
-
Blandino, G. et al. Metformin elicits anticancer effects through the sequential modulation of DICER and c MYC. Nat. Commun. 3, 865 (2012
-
(2012)
Nat. Commun
, vol.3
, Issue.865
-
-
Blandino, G.1
-
140
-
-
79955834631
-
Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in vivo
-
Rattan, R., Graham, R. P., Maguire, J. L., Giri, S. & Shridhar, V. Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in vivo. Neoplasia 13, 483-491 (2011
-
(2011)
Neoplasia
, vol.13
, pp. 483-491
-
-
Rattan, R.1
Graham, R.P.2
Maguire, J.L.3
Giri, S.4
Shridhar, V.5
-
141
-
-
84867405520
-
Metformin targets ovarian cancer stem cells in vitro and in vivo
-
Shank, J. J. et al. Metformin targets ovarian cancer stem cells in vitro and in vivo. Gynecol. Oncol. 127, 390-397 (2012
-
(2012)
Gynecol. Oncol
, vol.127
, pp. 390-397
-
-
Shank, J.J.1
-
142
-
-
58149156184
-
Therapeutic metformin/ampk activation promotes the angiogenic phenotype in the erα negative mda mb 435 breast cancer model
-
Phoenix, K. N., Vumbaca, F. & Claffey, K. P. Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERα negative MDA MB 435 breast cancer model. Breast Cancer Res. Treat. 113, 101-111 (2009
-
(2009)
Breast Cancer Res. Treat
, vol.113
, pp. 101-111
-
-
Phoenix, K.N.1
Vumbaca, F.2
Claffey, K.P.3
-
143
-
-
84864059240
-
Metformin accelerates the growth of BRAFV600E-driven melanoma by upregulating VEGF-A
-
Martin, M. J., Hayward, R., Viros, A. & Marais, R. Metformin accelerates the growth of BRAFV600E-driven melanoma by upregulating VEGF-A. Cancer Discov. 2, 344-355 (2012
-
(2012)
Cancer Discov
, vol.2
, pp. 344-355
-
-
Martin, M.J.1
Hayward, R.2
Viros, A.3
Marais, R.4
-
144
-
-
27944450832
-
Diabetes mellitus and risk of colorectal cancer: A meta-analysis
-
Larsson, S. C., Orsini, N. & Wolk, A. Diabetes mellitus and risk of colorectal cancer: A meta-analysis. J. Natl Cancer Inst. 97, 1679-1687 (2005
-
(2005)
J. Natl Cancer Inst
, vol.97
, pp. 1679-1687
-
-
Larsson, S.C.1
Orsini, N.2
Wolk, A.3
-
145
-
-
0041668140
-
Type 2 diabetes and subsequent incidence of breast cancer in the nurses' health study
-
Michels, K. B. et al. Type 2 diabetes and subsequent incidence of breast cancer in the Nurses' Health Study. Diabetes Care 26, 1752-1758 (2003
-
(2003)
Diabetes Care
, vol.26
, pp. 1752-1758
-
-
Michels, K.B.1
-
146
-
-
84867998462
-
Associations of type 2 diabetes and diabetes treatment with breast cancer risk and mortality: A population-based cohort study among british women
-
Redaniel, M. T., Jeffreys, M., May, M. T., Ben Shlomo, Y. & Martin, R. M. Associations of type 2 diabetes and diabetes treatment with breast cancer risk and mortality: A population-based cohort study among British women. Cancer Causes Control 23, 1785-1795 (2012
-
(2012)
Cancer Causes Control
, vol.23
, pp. 1785-1795
-
-
Redaniel, M.T.1
Jeffreys, M.2
May, M.T.3
Ben Shlomo, Y.4
Martin, R.M.5
-
147
-
-
84867899884
-
Diabetes and breast cancer risk: A meta-analysis
-
Boyle, P. et al. Diabetes and breast cancer risk: A meta-analysis. Br. J. Cancer 107, 1608-1617 (2012
-
(2012)
Br. J. Cancer
, vol.107
, pp. 1608-1617
-
-
Boyle, P.1
-
148
-
-
84862870270
-
Diabetes and lung cancer among postmenopausal women
-
Luo, J. et al. Diabetes and lung cancer among postmenopausal women. Diabetes Care 35, 1485-1491 (2012
-
(2012)
Diabetes Care
, vol.35
, pp. 1485-1491
-
-
Luo, J.1
-
149
-
-
84874109943
-
Type 2 diabetes mellitus, insulin use, and risk of bladder cancer in a large cohort study
-
Newton, C. C., Gapstur, S. M., Campbell, P. T. & Jacobs, E. J. Type 2 diabetes mellitus, insulin use, and risk of bladder cancer in a large cohort study. Int. J. Cancer 132, 2186-2191 (2013
-
(2013)
Int. J. Cancer
, vol.132
, pp. 2186-2191
-
-
Newton, C.C.1
Gapstur, S.M.2
Campbell, P.T.3
Jacobs, E.J.4
-
150
-
-
33845328853
-
A meta-analysis of diabetes mellitus and the risk of prostate cancer
-
Kasper, J. S. & Giovannucci, E. A meta-analysis of diabetes mellitus and the risk of prostate cancer. Cancer Epidemiol. Biomarkers Prev. 15, 2056-2062 (2006
-
(2006)
Cancer Epidemiol. Biomarkers Prev
, vol.15
, pp. 2056-2062
-
-
Kasper, J.S.1
Giovannucci, E.2
-
151
-
-
84865414136
-
Diabetes and cancer (1): Evaluating the temporal relationship between type 2 diabetes and cancer incidence
-
Johnson, J. A. et al. Diabetes and cancer (1): Evaluating the temporal relationship between type 2 diabetes and cancer incidence. Diabetologia 55, 1607-1618 (2012
-
(2012)
Diabetologia
, vol.55
, pp. 1607-1618
-
-
Johnson, J.A.1
-
152
-
-
78649302320
-
Metformin and cancer risk in diabetic patients: A systematic review and meta-analysis
-
Decensi, A. et al. Metformin and cancer risk in diabetic patients: A systematic review and meta-analysis. Cancer Prev. Res. (Phila.) 3, 1451-1461 (2010
-
(2010)
Cancer Prev. Res. (Phila
, vol.3
, pp. 1451-1461
-
-
Decensi, A.1
-
153
-
-
84858695046
-
Cancer risk in diabetic patients treated with metformin: A systematic review and meta-analysis
-
Noto, H., Goto, A., Tsujimoto, T. & Noda, M. Cancer risk in diabetic patients treated with metformin: A systematic review and meta-analysis. PLoS ONE 7, e33411 (2012
-
(2012)
PLoS ONE
, vol.7
-
-
Noto, H.1
Goto, A.2
Tsujimoto, T.3
Noda, M.4
-
154
-
-
84858693012
-
Reduced risk of colorectal cancer with metformin therapy in patients with type 2 diabetes: A meta-analysis
-
Zhang, Z. J. et al. Reduced risk of colorectal cancer with metformin therapy in patients with type 2 diabetes: A meta-analysis. Diabetes Care 34, 2323-2328 (2011
-
(2011)
Diabetes Care
, vol.34
, pp. 2323-2328
-
-
Zhang, Z.J.1
-
155
-
-
84866548333
-
Metformin and breast cancer risk: A meta-analysis and critical literature review
-
Col, N. F., Ochs, L., Springmann, V., Aragaki, A. K. & Chlebowski, R. T. Metformin and breast cancer risk: A meta-analysis and critical literature review. Breast Cancer Res. Treat. 135, 639-646 (2012
-
(2012)
Breast Cancer Res. Treat
, vol.135
, pp. 639-646
-
-
Col, N.F.1
Ochs, L.2
Springmann, V.3
Aragaki, A.K.4
Chlebowski, R.T.5
-
156
-
-
84869788946
-
Metformin and the risk of cancer: Time-related biases in observational studies
-
Suissa, S. & Azoulay, L. Metformin and the risk of cancer: Time-related biases in observational studies. Diabetes Care 35, 2665-2673 (2012
-
(2012)
Diabetes Care
, vol.35
, pp. 2665-2673
-
-
Suissa, S.1
Azoulay, L.2
-
157
-
-
77955558076
-
Experience of malignancies with oral glucose-lowering drugs in the randomised controlled adopt (a diabetes outcome progression trial) and record (rosiglitazone evaluated for cardiovascular outcomes and regulation of glycaemia in diabetes) clinical trials
-
Home, P. D. et al. Experience of malignancies with oral glucose-lowering drugs in the randomised controlled ADOPT (A Diabetes Outcome Progression Trial) and RECORD (Rosiglitazone Evaluated for Cardiovascular Outcomes and Regulation of Glycaemia in Diabetes) clinical trials. Diabetologia 53, 1838-1845 (2010
-
(2010)
Diabetologia
, vol.53
, pp. 1838-1845
-
-
Home, P.D.1
-
158
-
-
84864075329
-
Dual effect of metformin on breast cancer proliferation in a randomized presurgical trial
-
Bonanni, B. et al. Dual effect of metformin on breast cancer proliferation in a randomized presurgical trial. J. Clin. Oncol. 30, 2593-2600 (2012
-
(2012)
J. Clin. Oncol
, vol.30
, pp. 2593-2600
-
-
Bonanni, B.1
-
159
-
-
84866538325
-
Metformin in early breast cancer: A prospective window of opportunity neoadjuvant study
-
Niraula, S. et al. Metformin in early breast cancer: A prospective window of opportunity neoadjuvant study. Breast Cancer Res. Treat. 135, 821-830 (2012
-
(2012)
Breast Cancer Res. Treat
, vol.135
, pp. 821-830
-
-
Niraula, S.1
-
160
-
-
79960845901
-
Evidence for biological effects of metformin in operable breast cancer: A pre-operative, window of opportunity, randomized trial
-
Hadad, S. et al. Evidence for biological effects of metformin in operable breast cancer: A pre-operative, window of opportunity, randomized trial. Breast Cancer Res. Treat. 128, 783-794 (2011
-
(2011)
Breast Cancer Res. Treat
, vol.128
, pp. 783-794
-
-
Hadad, S.1
-
161
-
-
77956411030
-
Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial
-
Hosono, K. et al. Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial. Cancer Prev. Res. (Phila.) 3, 1077-1083 (2010
-
(2010)
Cancer Prev. Res. (Phila
, vol.3
, pp. 1077-1083
-
-
Hosono, K.1
-
162
-
-
84861726854
-
-
ClinicalTrials.gov[online
-
US National Library of Medicine. ClinicalTrials.gov[online], http://clinicaltrials.gov/ct2/show/NCT01312467 (2013
-
(2013)
US National Library Of Medicine
-
-
-
163
-
-
84861726854
-
-
ClinicalTrials.gov[online
-
US National Library of Medicine. ClinicalTrials.gov[online], http://clinicaltrials.gov/ct2/show/NCT01793948 (2013
-
(2013)
US National Library Of Medicine
-
-
-
164
-
-
84861726854
-
-
ClinicalTrials.gov[online
-
US National Library of Medicine. ClinicalTrials.gov[online], http://clinicaltrials.gov/ct2/show/NCT01447927 (2013
-
(2013)
US National Library Of Medicine
-
-
-
165
-
-
84861726854
-
-
ClinicalTrials.gov[online
-
US National Library of Medicine. ClinicalTrials.gov[online], http://clinicaltrials.gov/ct2/show/NCT01905046 (2013
-
(2013)
US National Library Of Medicine
-
-
-
166
-
-
84858729797
-
Metformin efficacy and safety for colorectal polyps: A double-blind randomized controlled trial
-
Higurashi, T. et al. Metformin efficacy and safety for colorectal polyps: A double-blind randomized controlled trial. BMC Cancer 12, 118 (2012
-
(2012)
BMC Cancer
, vol.12
, Issue.118
-
-
Higurashi, T.1
-
167
-
-
0036070666
-
Involvement of organic cation transporter 1 in the hepatic and intestinal distribution of metformin
-
Wang, D. S. et al. Involvement of organic cation transporter 1 in the hepatic and intestinal distribution of metformin. J. Pharmacol. Exp. Ther. 302, 510-515 (2002
-
(2002)
J. Pharmacol. Exp. Ther
, vol.302
, pp. 510-515
-
-
Wang, D.S.1
-
168
-
-
34248156160
-
Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action
-
Shu, Y. et al. Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action. J. Clin. Invest. 117, 1422-1431 (2007
-
(2007)
J. Clin. Invest
, vol.117
, pp. 1422-1431
-
-
Shu, Y.1
-
169
-
-
79251612707
-
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes
-
Zhou, K. et al. Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat. Genet. 43, 117-120 (2011
-
(2011)
Nat. Genet
, vol.43
, pp. 117-120
-
-
Zhou, K.1
-
170
-
-
84887404800
-
-
Ch. 39 (eds Waldman, S. A. & Terzic, A Elsevier, Amsterdam
-
Clarke, L. C. & Khosla, S. in Pharmacology and Therapeutics: Principles to practice Ch. 39 (eds Waldman, S. A. & Terzic, A.) 587-610 (Elsevier, Amsterdam, 2009
-
(2009)
Pharmacology And Therapeutics: Principles To Practice
, pp. 587-610
-
-
Clarke, L.C.1
Khosla, S.2
-
171
-
-
33744762777
-
Bisphosphonates: From bench to bedside
-
Russell, R. G. Bisphosphonates: From bench to bedside. Ann. N. Y. Acad. Sci. 1068, 367-401 (2006
-
(2006)
Ann. N. Y. Acad. Sci
, vol.1068
, pp. 367-401
-
-
Russell, R.G.1
-
172
-
-
73449089472
-
Bisphosphonates suppress insulin-like growth factor 1 induced angiogenesis via the HIF-1α/VEGF signaling pathways in human breast cancer cells
-
Tang, X. et al. Bisphosphonates suppress insulin-like growth factor 1 induced angiogenesis via the HIF-1α/VEGF signaling pathways in human breast cancer cells. Int. J. Cancer 126, 90-103 (2010
-
(2010)
Int. J. Cancer
, vol.126
, pp. 90-103
-
-
Tang, X.1
-
173
-
-
0037029682
-
The bisphosphonate zoledronic acid impairs Ras membrane[correction of impairs membrane] localisation and induces cytochrome c release in breast cancer cells
-
Senaratne, S. G., Mansi, J. L. & Colston, K. W. The bisphosphonate zoledronic acid impairs Ras membrane[correction of impairs membrane] localisation and induces cytochrome c release in breast cancer cells. Br. J. Cancer 86, 1479-1486 (2002
-
(2002)
Br. J. Cancer
, vol.86
, pp. 1479-1486
-
-
Senaratne, S.G.1
Mansi, J.L.2
Colston, K.W.3
-
174
-
-
3042729728
-
Zoledronic acid inhibits visceral metastases in the 4T1/luc mouse breast cancer model
-
Hiraga, T., Williams, P. J., Ueda, A., Tamura, D. & Yoneda, T. Zoledronic acid inhibits visceral metastases in the 4T1/luc mouse breast cancer model. Clin. Cancer Res. 10, 4559-4567 (2004
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 4559-4567
-
-
Hiraga, T.1
Williams, P.J.2
Ueda, A.3
Tamura, D.4
Yoneda, T.5
-
175
-
-
0034107048
-
Bisphosphonates induce apoptosis in human breast cancer cell lines
-
Senaratne, S. G., Pirianov, G., Mansi, J. L., Arnett, T. R. & Colston, K. W. Bisphosphonates induce apoptosis in human breast cancer cell lines. Br. J. Cancer 82, 1459-1468 (2000
-
(2000)
Br. J. Cancer
, vol.82
, pp. 1459-1468
-
-
Senaratne, S.G.1
Pirianov, G.2
Mansi, J.L.3
Arnett, T.R.4
Colston, K.W.5
-
176
-
-
38749122501
-
Zoledronic acid is unable to induce apoptosis, but slows tumor growth and prolongs survival for non small cell lung cancers
-
Li, Y. Y. et al. Zoledronic acid is unable to induce apoptosis, but slows tumor growth and prolongs survival for non small cell lung cancers. Lung Cancer 59, 180-191 (2008
-
(2008)
Lung Cancer
, vol.59
, pp. 180-191
-
-
Li, Y.Y.1
-
177
-
-
78650303812
-
The kinetochore protein Cenp F is a potential novel target for zoledronic acid in breast cancer cells
-
Brown, H. K., Ottewell, P. D., Coleman, R. E. & Holen, I. The kinetochore protein Cenp F is a potential novel target for zoledronic acid in breast cancer cells. J. Cell. Mol. Med. 15, 501-513 (2011
-
(2011)
J. Cell. Mol. Med
, vol.15
, pp. 501-513
-
-
Brown, H.K.1
Ottewell, P.D.2
Coleman, R.E.3
Holen, I.4
-
178
-
-
78650051896
-
Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway
-
Coscia, M. et al. Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway. J. Cell. Mol. Med. 14, 2803-2815 (2010
-
(2010)
J. Cell. Mol. Med
, vol.14
, pp. 2803-2815
-
-
Coscia, M.1
-
179
-
-
37049006066
-
Amino biphosphonate mediated MMP 9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma
-
Melani, C., Sangaletti, S., Barazzetta, F. M., Werb, Z. & Colombo, M. P. Amino biphosphonate mediated MMP 9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma. Cancer Res. 67, 11438-11446 (2007
-
(2007)
Cancer Res
, vol.67
, pp. 11438-11446
-
-
Melani, C.1
Sangaletti, S.2
Barazzetta, F.M.3
Werb, Z.4
Colombo, M.P.5
-
180
-
-
33847771427
-
Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis
-
Daubiné, F., Le Gall, C., Gasser, J., Green, J. & Clézardin, P. Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis. J. Natl Cancer Inst. 99, 322-330 (2007
-
(2007)
J. Natl Cancer Inst
, vol.99
, pp. 322-330
-
-
Daubiné, F.1
Le Gall, C.2
Gasser, J.3
Green, J.4
Clézardin, P.5
-
181
-
-
33846483160
-
Alendronate suppresses tumor angiogenesis by inhibiting Rho activation of endothelial cells
-
Hashimoto, K. et al. Alendronate suppresses tumor angiogenesis by inhibiting Rho activation of endothelial cells. Biochem. Biophys. Res. Commun. 354, 478-484 (2007
-
(2007)
Biochem. Biophys. Res. Commun
, vol.354
, pp. 478-484
-
-
Hashimoto, K.1
-
182
-
-
34547653957
-
Repeated intermittent low-dose therapy with zoledronic acid induces an early, sustained, and long-lasting decrease of peripheral vascular endothelial growth factor levels in cancer patients
-
Santini, D. et al. Repeated intermittent low-dose therapy with zoledronic acid induces an early, sustained, and long-lasting decrease of peripheral vascular endothelial growth factor levels in cancer patients. Clin. Cancer Res. 13 (15 Pt 1), 4482-4486 (2007
-
(2007)
Clin. Cancer Res
, vol.13
, Issue.15 PART1
, pp. 4482-4486
-
-
Santini, D.1
-
183
-
-
54849441655
-
In vivo effects of zoledronic acid on peripheral gammadelta T lymphocytes in early breast cancer patients
-
Santini, D. et al. In vivo effects of zoledronic acid on peripheral gammadelta T lymphocytes in early breast cancer patients. Cancer Immunol. Immunother. 58, 31-38 (2009
-
(2009)
Cancer Immunol. Immunother
, vol.58
, pp. 31-38
-
-
Santini, D.1
-
184
-
-
0032491037
-
Reduction in new metastases in breast cancer with adjuvant clodronate treatment
-
Diel, I. J. et al. Reduction in new metastases in breast cancer with adjuvant clodronate treatment. N. Engl. J. Med. 339, 357-363 (1998
-
(1998)
N. Engl. J. Med
, vol.339
, pp. 357-363
-
-
Diel, I.J.1
-
185
-
-
0036682211
-
Randomized, placebo-controlled trial of clodronate in patients with primary operable breast cancer
-
Powles, T. et al. Randomized, placebo-controlled trial of clodronate in
-
(2002)
J. Clin. Oncol
, vol.20
, pp. 3219-3224
-
-
Powles, T.1
-
186
-
-
9444254706
-
Ten-year follow-up of a randomized controlled trial of adjuvant clodronate treatment in node-positive breast cancer patients
-
Saarto, T., Vehmanen, L., Virkkunen, P. & Blomqvist, C. Ten-year follow-up of a randomized controlled trial of adjuvant clodronate treatment in node-positive breast cancer patients. Acta Oncol. 43, 650-656 (2004
-
(2004)
Acta Oncol
, vol.43
, pp. 650-656
-
-
Saarto, T.1
Vehmanen, L.2
Virkkunen, P.3
Blomqvist, C.4
-
187
-
-
45149083364
-
Bisphosphonate treatment in primary breast cancer: Results from a randomised comparison of oral pamidronate versus no pamidronate in patients with primary breast cancer
-
Kristensen, B. et al. Bisphosphonate treatment in primary breast cancer: Results from a randomised comparison of oral pamidronate versus no pamidronate in patients with primary breast cancer. Acta Oncol. 47, 740-746 (2008
-
(2008)
Acta Oncol
, vol.47
, pp. 740-746
-
-
Kristensen, B.1
-
188
-
-
60549097419
-
Endocrine therapy plus zoledronic acid in premenopausal breast cancer
-
Gnant, M. et al. Endocrine therapy plus zoledronic acid in premenopausal breast cancer. N. Engl. J. Med. 360, 679-691 (2009
-
(2009)
N. Engl. J. Med
, vol.360
, pp. 679-691
-
-
Gnant, M.1
-
189
-
-
79959565208
-
Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 62-month follow-up from the ABCSG 12 randomised trial
-
Gnant, M. et al. Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 62-month follow-up from the ABCSG 12 randomised trial. Lancet Oncol. 12, 631-641 (2011
-
(2011)
Lancet Oncol
, vol.12
, pp. 631-641
-
-
Gnant, M.1
-
190
-
-
77952305169
-
Effect of zoledronic acid on disseminated tumour cells in women with locally advanced breast cancer: An open label, randomised, phase 2 trial
-
Aft, R. et al. Effect of zoledronic acid on disseminated tumour cells in women with locally advanced breast cancer: An open label, randomised, phase 2 trial. Lancet Oncol. 11, 421-428 (2010
-
(2010)
Lancet Oncol
, vol.11
, pp. 421-428
-
-
Aft, R.1
-
191
-
-
80054035939
-
Breast-cancer adjuvant therapy with zoledronic acid
-
Coleman, R. E. et al. Breast-cancer adjuvant therapy with zoledronic acid. N. Engl. J. Med. 365, 1396-1405 (2011
-
(2011)
N. Engl. J. Med
, vol.365
, pp. 1396-1405
-
-
Coleman, R.E.1
-
192
-
-
77950370156
-
The effects of adding zoledronic acid to neoadjuvant chemotherapy on tumour response: Exploratory evidence for direct anti-tumour activity in breast cancer
-
Coleman, R. E. et al. The effects of adding zoledronic acid to neoadjuvant chemotherapy on tumour response: Exploratory evidence for direct anti-tumour activity in breast cancer. Br. J. Cancer 102, 1099-1105 (2010
-
(2010)
Br. J. Cancer
, vol.102
, pp. 1099-1105
-
-
Coleman, R.E.1
-
193
-
-
84862986485
-
Effect of (Neo)adjuvant zoledronic acid on disease-free and overall survival in clinical stage II/III breast cancer
-
Aft, R. L., Naughton, M., Trinkaus, K. & Weilbaecher, K. Effect of (Neo)adjuvant zoledronic acid on disease-free and overall survival in clinical stage II/III breast cancer. Br. J. Cancer 107, 7-11 (2012
-
(2012)
Br. J. Cancer
, vol.107
, pp. 7-11
-
-
Aft, R.L.1
Naughton, M.2
Trinkaus, K.3
Weilbaecher, K.4
-
194
-
-
84873825231
-
Zoledronic acid (zoledronate) for postmenopausal women with early breast cancer receiving adjuvant letrozole (ZO-FAST study): Final 60-month results
-
Coleman, R. et al. Zoledronic acid (zoledronate) for postmenopausal women with early breast cancer receiving adjuvant letrozole (ZO-FAST study): Final 60-month results. Ann. Oncol. 24, 398-405 (2013
-
(2013)
Ann. Oncol
, vol.24
, pp. 398-405
-
-
Coleman, R.1
-
195
-
-
84863109831
-
Oral clodronate for adjuvant treatment of operable breast cancer (national surgical adjuvant breast and bowel project protocol b 34): A multicentre, placebo-controlled, randomised trial
-
Paterson, A. H. et al. Oral clodronate for adjuvant treatment of operable breast cancer (National Surgical Adjuvant Breast and Bowel Project protocol B 34): A multicentre, placebo-controlled, randomised trial. Lancet Oncol. 13, 734-742 (2012
-
(2012)
Lancet Oncol
, vol.13
, pp. 734-742
-
-
Paterson, A.H.1
-
196
-
-
77649269901
-
Bisphosphonates for osteoporosis treatment are associated with reduced breast cancer risk
-
Newcomb, P. A., Trentham-Dietz, A. & Hampton, J. M. Bisphosphonates for osteoporosis treatment are associated with reduced breast cancer risk. Br. J. Cancer 102, 799-802 (2010
-
(2010)
Br. J. Cancer
, vol.102
, pp. 799-802
-
-
Newcomb, P.A.1
Trentham-Dietz, A.2
Hampton, J.M.3
-
197
-
-
77955875028
-
Oral bisphosphonate use and breast cancer incidence in postmenopausal women
-
Chlebowski, R. T. et al. Oral bisphosphonate use and breast cancer incidence in postmenopausal women. J. Clin. Oncol. 28, 3582-3590 (2010
-
(2010)
J. Clin. Oncol
, vol.28
, pp. 3582-3590
-
-
Chlebowski, R.T.1
-
198
-
-
77955870208
-
Use of bisphosphonates and risk of postmenopausal breast cancer
-
Rennert, G., Pinchev, M. & Rennert, H. S. Use of bisphosphonates and risk of postmenopausal breast cancer. J. Clin. Oncol. 28, 3577-3581 (2010
-
(2010)
J. Clin. Oncol
, vol.28
, pp. 3577-3581
-
-
Rennert, G.1
Pinchev, M.2
Rennert, H.S.3
-
199
-
-
83255173945
-
Bisphosphonate use after estrogen receptor-positive breast cancer and risk of contralateral breast cancer
-
Monsees, G. M., Malone, K. E., Tang, M. T., Newcomb, P. A. & Li, C. I. Bisphosphonate use after estrogen receptor-positive breast cancer and risk of contralateral breast cancer. J. Natl Cancer Inst. 103, 1752-1760 (2011
-
(2011)
J. Natl Cancer Inst
, vol.103
, pp. 1752-1760
-
-
Monsees, G.M.1
Malone, K.E.2
Tang, M.T.3
Newcomb, P.A.4
Li, C.I.5
-
200
-
-
79952757671
-
Use of bisphosphonates and reduced risk of colorectal cancer
-
Rennert, G., Pinchev, M., Rennert, H. S. & Gruber, S. B. Use of bisphosphonates and reduced risk of colorectal cancer. J. Clin. Oncol. 29, 1146-1150 (2011
-
(2011)
J. Clin. Oncol
, vol.29
, pp. 1146-1150
-
-
Rennert, G.1
Pinchev, M.2
Rennert, H.S.3
Gruber, S.B.4
-
201
-
-
84868302116
-
Reduced colon cancer incidence and mortality in postmenopausal women treated with an oral bisphosphonate-danish national register based cohort study
-
Pazianas, M., Abrahamsen, B., Eiken, P. A., Eastell, R. & Russell, R. G. Reduced colon cancer incidence and mortality in postmenopausal women treated with an oral bisphosphonate-Danish National Register Based Cohort Study. Osteoporos. Int. 23, 2693-2701 (2012
-
(2012)
Osteoporos. Int
, vol.23
, pp. 2693-2701
-
-
Pazianas, M.1
Abrahamsen, B.2
Eiken, P.A.3
Eastell, R.4
Russell, R.G.5
-
202
-
-
83255191619
-
Exposure to bisphosphonates and risk of colorectal cancer: A population-based nested case-control study
-
Singh, H., Nugent, Z., Demers, A., Mahmud, S. & Bernstein, C. Exposure to bisphosphonates and risk of colorectal cancer: A population-based nested case-control study. Cancer 118, 1236-1243 (2012
-
(2012)
Cancer
, vol.118
, pp. 1236-1243
-
-
Singh, H.1
Nugent, Z.2
Demers, A.3
Mahmud, S.4
Bernstein, C.5
-
203
-
-
84866555641
-
A prospective study of bisphosphonate use and risk of colorectal cancer
-
Khalili, H., Huang, E. S., Ogino, S., Fuchs, C. S. & Chan, A. T. A prospective study of bisphosphonate use and risk of colorectal cancer. J. Clin. Oncol. 30, 3229-3233 (2012
-
(2012)
J. Clin. Oncol
, vol.30
, pp. 3229-3233
-
-
Khalili, H.1
Huang, E.S.2
Ogino, S.3
Fuchs, C.S.4
Chan, A.T.5
-
204
-
-
84882580219
-
Oral bisphosphonate use and colorectal cancer incidence in the women's health initiative
-
Passarelli, M. N. et al. Oral bisphosphonate use and colorectal cancer incidence in the Women's Health Initiative. J. Bone Miner. Res. http://dx.doi.org/10.1002/jbmr.1930
-
J. Bone Miner. Res
-
-
Passarelli, M.N.1
-
205
-
-
34447273333
-
Oral sodium clodronate for nonmetastatic prostate cancer-results of a randomized double-blind placebo-controlled trial: Medical research council pr04 (isrctn61384873
-
Mason, M. D. et al. Oral sodium clodronate for nonmetastatic prostate cancer-results of a randomized double-blind placebo-controlled trial: Medical Research Council PR04 (ISRCTN61384873). J. Natl Cancer Inst. 99, 765-776 (2007
-
(2007)
J. Natl Cancer Inst
, vol.99
, pp. 765-776
-
-
Mason, M.D.1
-
206
-
-
77956542068
-
Oral bisphosphonates and risk of cancer of oesophagus, stomach, and colorectum: Case-control analysis within a UK primary care cohort
-
Green, J. et al. Oral bisphosphonates and risk of cancer of oesophagus, stomach, and colorectum: Case-control analysis within a UK primary care cohort. BMJ 341, c4444 (2010
-
(2010)
BMJ
, vol.341
-
-
Green, J.1
-
207
-
-
77955369368
-
Exposure to oral bisphosphonates and risk of esophageal cancer
-
Cardwell, C. R., Abnet, C. C., Cantwell, M. M. & Murray, L. J. Exposure to oral bisphosphonates and risk of esophageal cancer. JAMA 304, 657-663 (2010
-
(2010)
JAMA
, vol.304
, pp. 657-663
-
-
Cardwell, C.R.1
Abnet, C.C.2
Cantwell, M.M.3
Murray, L.J.4
-
208
-
-
84865268918
-
Oral alendronate use and risk of cancer in postmenopausal women with osteoporosis: A nationwide study
-
Chiang, C. H. et al. Oral alendronate use and risk of cancer in postmenopausal women with osteoporosis: A nationwide study. J. Bone Miner. Res. 27, 1951-1958 (2012
-
(2012)
J. Bone Miner. Res
, vol.27
, pp. 1951-1958
-
-
Chiang, C.H.1
-
209
-
-
84863195997
-
Exposure to oral bisphosphonates and risk of cancer
-
Cardwell, C. R. et al. Exposure to oral bisphosphonates and risk of cancer. Int. J. Cancer 131, E717-E725 (2012
-
(2012)
Int. J. Cancer
, vol.131
-
-
Cardwell, C.R.1
-
210
-
-
84864776057
-
Bisphosphonate use and the risk of breast cancer: A meta-analysis of published literature
-
Liu, Y. et al. Bisphosphonate use and the risk of breast cancer: A meta-analysis of published literature. Clin. Breast Cancer 12, 276-281 (2012
-
(2012)
Clin. Breast Cancer
, vol.12
, pp. 276-281
-
-
Liu, Y.1
-
211
-
-
84875466027
-
Reduced risk of colorectal cancer with use of oral bisphosphonates: A systematic review and meta-analysis
-
Thosani, N. et al. Reduced risk of colorectal cancer with use of oral bisphosphonates: A systematic review and meta-analysis. J. Clin. Oncol. 31, 623-630 (2013
-
(2013)
J. Clin. Oncol
, vol.31
, pp. 623-630
-
-
Thosani, N.1
-
212
-
-
84861726854
-
-
ClinicalTrials.gov[online
-
US National Library of Medicine. ClinicalTrials.gov[online], http://clinicaltrials.gov/ct2/show/NCT00127205 (2013
-
(2013)
US National Library Of Medicine
-
-
-
213
-
-
84861726854
-
-
ClinicalTrials.gov[online
-
US National Library of Medicine. ClinicalTrials.gov[online], http://clinicaltrials.gov/ct2/show/NCT00295646 (2013
-
(2013)
US National Library Of Medicine
-
-
-
214
-
-
84861726854
-
-
ClinicalTrials.gov[online
-
US National Library of Medicine. ClinicalTrials.gov[online], http://clinicaltrials.gov/ct2/show/record/NCT00295867 (2012
-
(2012)
US National Library Of Medicine
-
-
-
215
-
-
84861726854
-
-
ClinicalTrials.gov[online
-
US National Library of Medicine. ClinicalTrials.gov[online], http://clinicaltrials.gov/ct2/show/NCT00892242 (2013
-
(2013)
US National Library Of Medicine
-
-
-
216
-
-
78649350233
-
Pharmacogenetics of osteoporosis
-
Marini, F. & Brandi, M. L. Pharmacogenetics of osteoporosis. F1000 Biol. Rep. 2, 63 (2010
-
(2010)
F1000 Biol. Rep
, vol.2
, Issue.63
-
-
Marini, F.1
Brandi, M.L.2
-
217
-
-
84860331458
-
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
-
Estrada, K. et al. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat. Genet. 44, 491-501 (2012
-
(2012)
Nat. Genet
, vol.44
, pp. 491-501
-
-
Estrada, K.1
-
218
-
-
69549097703
-
New users of metformin are at low risk of incident cancer: A cohort study among people with type 2 diabetes
-
Libby, G. et al. New users of metformin are at low risk of incident cancer: A cohort study among people with type 2 diabetes. Diabetes Care 32, 1620-1625 (2009
-
(2009)
Diabetes Care
, vol.32
, pp. 1620-1625
-
-
Libby, G.1
-
219
-
-
68449094325
-
The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
-
Currie, C. J., Poole, C. D. & Gale, E. A. The influence of glucose-lowering therapies on cancer risk in type 2 diabetes. Diabetologia 52, 1766-1777 (2009
-
(2009)
Diabetologia
, vol.52
, pp. 1766-1777
-
-
Currie, C.J.1
Poole, C.D.2
Gale, E.A.3
-
220
-
-
84865084381
-
Diabetes, metformin, and breast cancer in postmenopausal women
-
Chlebowski, R. T. et al. Diabetes, metformin, and breast cancer in postmenopausal women. J. Clin. Oncol. 30, 2844-2852 (2012
-
(2012)
J. Clin. Oncol
, vol.30
, pp. 2844-2852
-
-
Chlebowski, R.T.1
-
221
-
-
67749144226
-
Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer
-
Jiralerspong, S. et al. Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer. J. Clin. Oncol. 27, 3297-3302 (2009
-
(2009)
J. Clin. Oncol
, vol.27
, pp. 3297-3302
-
-
Jiralerspong, S.1
-
222
-
-
77953539812
-
Long-term metformin use is associated with decreased risk of breast cancer
-
Bodmer, M., Meier, C., Krähenbühl, S., Jick, S. S. & Meier, C. R. Long-term metformin use is associated with decreased risk of breast cancer. Diabetes Care 33, 1304-1308 (2010
-
(2010)
Diabetes Care
, vol.33
, pp. 1304-1308
-
-
Bodmer, M.1
Meier, C.2
Krähenbühl, S.3
Jick, S.S.4
Meier, C.R.5
-
223
-
-
78651415908
-
Metformin and incident breast cancer among diabetic women: A population-based case-control study in denmark
-
Bosco, J. L., Antonsen, S., Sørensen, H. T., Pedersen, L. & Lash, T. L. Metformin and incident breast cancer among diabetic women: A population-based case-control study in Denmark. Cancer Epidemiol. Biomarkers Prev. 20, 101-111 (2011
-
(2011)
Cancer Epidemiol. Biomarkers Prev
, vol.20
, pp. 101-111
-
-
Bosco, J.L.1
Antonsen, S.2
Sørensen, H.T.3
Pedersen, L.4
Lash, T.L.5
-
224
-
-
84857073798
-
Use of metformin is not associated with a decreased risk of colorectal cancer: A case-control analysis
-
Bodmer, M., Becker, C., Meier, C., Jick, S. S. & Meier, C. R. Use of metformin is not associated with a decreased risk of colorectal cancer: A case-control analysis. Cancer Epidemiol. Biomarkers Prev. 21, 280-286 (2012
-
(2012)
Cancer Epidemiol. Biomarkers Prev
, vol.21
, pp. 280-286
-
-
Bodmer, M.1
Becker, C.2
Meier, C.3
Jick, S.S.4
Meier, C.R.5
-
225
-
-
84867404716
-
Metformin does not alter the risk of lung cancer: A case-control analysis
-
Bodmer, M., Becker, C., Jick, S. S. & Meier, C. R. Metformin does not alter the risk of lung cancer: A case-control analysis. Lung Cancer 78, 133-137 (2012
-
(2012)
Lung Cancer
, vol.78
, pp. 133-137
-
-
Bodmer, M.1
Becker, C.2
Jick, S.S.3
Meier, C.R.4
-
226
-
-
84872019209
-
The use of metformin and the incidence of lung cancer in patients with type 2 diabetes
-
Smiechowski, B. B., Azoulay, L., Yin, H., Pollak, M. N. & Suissa, S. The use of metformin and the incidence of lung cancer in patients with type 2 diabetes. Diabetes Care 36, 124-129 (2013
-
(2013)
Diabetes Care
, vol.36
, pp. 124-129
-
-
Smiechowski, B.B.1
Azoulay, L.2
Yin, H.3
Pollak, M.N.4
Suissa, S.5
-
227
-
-
67650945180
-
Antidiabetic therapies affect risk of pancreatic cancer
-
Li, D., Yeung, S. C., Hassan, M. M., Konopleva, M. & Abbruzzese, J. L. Antidiabetic therapies affect risk of pancreatic cancer. Gastroenterology 137, 482-488 (2009
-
(2009)
Gastroenterology
, vol.137
, pp. 482-488
-
-
Li, D.1
Yeung, S.C.2
Hassan, M.M.3
Konopleva, M.4
Abbruzzese, J.L.5
-
228
-
-
84859605287
-
Use of antidiabetic agents and the risk of pancreatic cancer: A case-control analysis
-
Bodmer, M., Becker, C., Meier, C., Jick, S. S. & Meier, C. R. Use of antidiabetic agents and the risk of pancreatic cancer: A case-control analysis. Am. J. Gastroenterol. 107, 620-626 (2012
-
(2012)
Am. J. Gastroenterol
, vol.107
, pp. 620-626
-
-
Bodmer, M.1
Becker, C.2
Meier, C.3
Jick, S.S.4
Meier, C.R.5
-
229
-
-
77951006620
-
Association of diabetes duration and diabetes treatment with the risk of epatocellular carcinoma
-
Hassan, M. M. et al. Association of diabetes duration and diabetes treatment with the risk of epatocellular carcinoma. Cancer 116, 1938-1946 (2010
-
(2010)
Cancer
, vol.116
, pp. 1938-1946
-
-
Hassan, M.M.1
-
230
-
-
56749165071
-
Adjuvant oral clodronate improves the overall survival of primary breast cancer patients with micrometastases to the bone marrow: A long-term follow-up
-
Diel, I. J. et al. Adjuvant oral clodronate improves the overall survival of primary breast cancer patients with micrometastases to the bone marrow: A long-term follow-up. Ann. Oncol. 19, 2007-2011 (2008
-
(2008)
Ann. Oncol
, vol.19
, pp. 2007-2011
-
-
Diel, I.J.1
-
231
-
-
77649269901
-
Bisphosphonates for osteoporosis treatment are associated with reduced breast cancer risk
-
Newcomb, P. A., Trentham-Dietz, A. & Hampton, J. M. Bisphosphonates for osteoporosis treatment are associated with reduced breast cancer risk. Br. J. Cancer 102, 799-802 (2010
-
(2010)
Br. J. Cancer
, vol.102
, pp. 799-802
-
-
Newcomb, P.A.1
Trentham-Dietz, A.2
Hampton, J.M.3
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