-
1
-
-
0017965207
-
Synthesis intracellular transport and discharge of exportable proteins in the pancreatic acinar cell and other cells
-
Case RM (1978) Synthesis, intracellular transport and discharge of exportable proteins in the pancreatic acinar cell and other cells. Biol Rev Camb Philos Soc 53(2):211-354.
-
(1978)
Biol Rev Camb Philos Soc
, vol.53
, Issue.2
, pp. 211-354
-
-
Case, R.M.1
-
2
-
-
84878953735
-
The role of protein synthesis and digestive enzymes in acinar cell injury
-
Logsdon CD, Ji B (2013) The role of protein synthesis and digestive enzymes in acinar cell injury. Nat Rev Gastroenterol Hepatol 10(6):362-370.
-
(2013)
Nat Rev Gastroenterol Hepatol
, vol.10
, Issue.6
, pp. 362-370
-
-
Logsdon, C.D.1
Ji, B.2
-
3
-
-
84906712846
-
The impact of the endoplasmic reticulum protein-folding environment on cancer development
-
WangM, Kaufman RJ (2014) The impact of the endoplasmic reticulum protein-folding environment on cancer development. Nat Rev Cancer 14(9):581-597.
-
(2014)
Nat Rev Cancer
, vol.14
, Issue.9
, pp. 581-597
-
-
WangM Kaufman, R.J.1
-
4
-
-
84907553770
-
Endoplasmic reticulum stress is chronically activated in chronic pancreatitis
-
Sah RP, et al. (2014) Endoplasmic reticulum stress is chronically activated in chronic pancreatitis. J Biol Chem 289(40):27551-27561.
-
(2014)
J Biol Chem
, vol.289
, Issue.40
, pp. 27551-27561
-
-
Sah, R.P.1
-
5
-
-
84946708563
-
-
eds Pagon RA, et al GeneReviews, University of Washington, Seattle
-
LaRusch J, Solomon S, Whitcomb DC (1993) Pancreatitis Overview, eds Pagon RA, et al. (GeneReviews, University of Washington, Seattle).
-
(1993)
Pancreatitis Overview
-
-
LaRusch, J.1
Solomon, S.2
Whitcomb, D.C.3
-
6
-
-
84934441610
-
The role of inflammation in pancreatic cancer
-
Hausmann S, Kong B, Michalski C, Erkan M, Friess H (2014) The role of inflammation in pancreatic cancer. Adv Exp Med Biol 816:129-151.
-
(2014)
Adv Exp Med Biol
, vol.816
, pp. 129-151
-
-
Hausmann, S.1
Kong, B.2
Michalski, C.3
Erkan, M.4
Friess, H.5
-
7
-
-
84876796439
-
Inflammation, autophagy, and obesity: Common features in the pathogenesis of pancreatitis and pancreatic cancer
-
Gukovsky I, Li N, Todoric J, Gukovskaya A, Karin M (2013) Inflammation, autophagy, and obesity: Common features in the pathogenesis of pancreatitis and pancreatic cancer. Gastroenterology 144(6):1199-1209
-
(2013)
Gastroenterology
, vol.144
, Issue.6
, pp. 1199-1209
-
-
Gukovsky, I.1
Li, N.2
Todoric, J.3
Gukovskaya, A.4
Karin, M.5
-
9
-
-
79955631150
-
Autophagy in the cellular energetic balance
-
Singh R, Cuervo AM (2011) Autophagy in the cellular energetic balance. Cell Metab 13(5):495-504.
-
(2011)
Cell Metab
, vol.13
, Issue.5
, pp. 495-504
-
-
Singh, R.1
Cuervo, A.M.2
-
10
-
-
78650448754
-
Chemical modulators of autophagy as biological probes and potential therapeutics
-
Fleming A, Noda T, Yoshimori T, Rubinsztein DC (2011) Chemical modulators of autophagy as biological probes and potential therapeutics. Nat Chem Biol 7(1):9-17.
-
(2011)
Nat Chem Biol
, vol.7
, Issue.1
, pp. 9-17
-
-
Fleming, A.1
Noda, T.2
Yoshimori, T.3
Rubinsztein, D.C.4
-
11
-
-
41049087959
-
Autophagy-physiology and pathophysiology
-
Uchiyama Y, Shibata M, Koike M, Yoshimura K, Sasaki M (2008) Autophagy-physiology and pathophysiology. Histochem Cell Biol 129(4):407-420.
-
(2008)
Histochem Cell Biol
, vol.129
, Issue.4
, pp. 407-420
-
-
Uchiyama, Y.1
Shibata, M.2
Koike, M.3
Yoshimura, K.4
Sasaki, M.5
-
13
-
-
46249114022
-
Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells
-
Hashimoto D, et al. (2008) Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells. J Cell Biol 181(7):1065-1072.
-
(2008)
J Cell Biol
, vol.181
, Issue.7
, pp. 1065-1072
-
-
Hashimoto, D.1
-
14
-
-
79953144994
-
Zymophagy, a novel selective autophagy pathway mediated by VMP1-USP9x-p62, prevents pancreatic cell death
-
Grasso D, et al. (2011) Zymophagy, a novel selective autophagy pathway mediated by VMP1-USP9x-p62, prevents pancreatic cell death. J Biol Chem 286(10):8308-8324.
-
(2011)
J Biol Chem
, vol.286
, Issue.10
, pp. 8308-8324
-
-
Grasso, D.1
-
15
-
-
84876789628
-
Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice
-
Li N, et al. (2013) Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice. J Clin Invest 123(5):2231-2243.
-
(2013)
J Clin Invest
, vol.123
, Issue.5
, pp. 2231-2243
-
-
Li, N.1
-
16
-
-
84923923847
-
Impaired autophagy induces chronic atrophic pancreatitis in mice via sex-And nutrition-dependent processes
-
Diakopoulos KN, et al. (2015) Impaired autophagy induces chronic atrophic pancreatitis in mice via sex-And nutrition-dependent processes. Gastroenterology 148(3): 626-638
-
(2015)
Gastroenterology
, vol.148
, Issue.3
, pp. 626-638
-
-
Diakopoulos, K.N.1
-
17
-
-
84923870567
-
Impaired autophagy triggers chronic pancreatitis: Lessons from pancreas-specific atg5 knockout mice
-
Gukovsky I, Gukovskaya AS (2015) Impaired autophagy triggers chronic pancreatitis: Lessons from pancreas-specific atg5 knockout mice. Gastroenterology 148(3):501-505.
-
(2015)
Gastroenterology
, vol.148
, Issue.3
, pp. 501-505
-
-
Gukovsky, I.1
Gukovskaya, A.S.2
-
18
-
-
70449426665
-
Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis
-
Mareninova OA, et al. (2009) Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis. J Clin Invest 119(11):3340-3355.
-
(2009)
J Clin Invest
, vol.119
, Issue.11
, pp. 3340-3355
-
-
Mareninova, O.A.1
-
19
-
-
84890432985
-
P53 status determines the role of autophagy in pancreatic tumour development
-
Rosenfeldt MT, et al. (2013) p53 status determines the role of autophagy in pancreatic tumour development. Nature 504(7479):296-300.
-
(2013)
Nature
, vol.504
, Issue.7479
, pp. 296-300
-
-
Rosenfeldt, M.T.1
-
20
-
-
84905499163
-
Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations
-
Yang A, et al. (2014) Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations. Cancer Discov 4(8):905-913.
-
(2014)
Cancer Discov
, vol.4
, Issue.8
, pp. 905-913
-
-
Yang, A.1
-
21
-
-
84897528091
-
Autophagy, p53, and pancreatic cancer
-
Iacobuzio-Donahue CA, Herman JM (2014) Autophagy, p53, and pancreatic cancer. N Engl J Med 370(14):1352-1353.
-
(2014)
N Engl J Med
, vol.370
, Issue.14
, pp. 1352-1353
-
-
Iacobuzio-Donahue, C.A.1
Herman, J.M.2
-
22
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
-
Komatsu M, et al. (2005) Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol 169(3):425-434.
-
(2005)
J Cell Biol
, vol.169
, Issue.3
, pp. 425-434
-
-
Komatsu, M.1
-
23
-
-
0035910423
-
The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-Activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3
-
Tanida I, Tanida-Miyake E, Ueno T, Kominami E (2001) The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-Activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3. J Biol Chem 276(3): 1701-1706.
-
(2001)
J Biol Chem
, vol.276
, Issue.3
, pp. 1701-1706
-
-
Tanida, I.1
Tanida-Miyake, E.2
Ueno, T.3
Kominami, E.4
-
24
-
-
84355162283
-
Canonical and non-canonical autophagy: Variations on a common theme of self-eating?
-
Codogno P, Mehrpour M, Proikas-Cezanne T (2012) Canonical and non-canonical autophagy: Variations on a common theme of self-eating? Nat Rev Mol Cell Biol 13(1):7-12.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, Issue.1
, pp. 7-12
-
-
Codogno, P.1
Mehrpour, M.2
Proikas-Cezanne, T.3
-
25
-
-
84868567192
-
When autophagy meets cancer through p62/SQSTM1
-
Puissant A, Fenouille N, Auberger P (2012) When autophagy meets cancer through p62/SQSTM1. Am J Cancer Res 2(4):397-413.
-
(2012)
Am J Cancer Res
, vol.2
, Issue.4
, pp. 397-413
-
-
Puissant, A.1
Fenouille, N.2
Auberger, P.3
-
26
-
-
84922561074
-
Myeloid malignancies with chromosome 5q deletions acquire a dependency on an intrachromosomal NF-κB gene network
-
Fang J, et al. (2014) Myeloid malignancies with chromosome 5q deletions acquire a dependency on an intrachromosomal NF-κB gene network. Cell Reports 8(5): 1328-1338.
-
(2014)
Cell Reports
, vol.8
, Issue.5
, pp. 1328-1338
-
-
Fang, J.1
-
27
-
-
77649265091
-
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
-
Komatsu M, et al. (2010) The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. Nat Cell Biol 12(3): 213-223.
-
(2011)
Nat Cell Biol
, vol.12
, Issue.3
, pp. 213-223
-
-
Komatsu, M.1
-
28
-
-
36248949141
-
The endoplasmic reticulum and the unfolded protein response
-
Malhotra JD, Kaufman RJ (2007) The endoplasmic reticulum and the unfolded protein response. Semin Cell Dev Biol 18(6):716-731.
-
(2007)
Semin Cell Dev Biol
, vol.18
, Issue.6
, pp. 716-731
-
-
Malhotra, J.D.1
Kaufman, R.J.2
-
29
-
-
84872192695
-
An involvement of oxidative stress in endoplasmic reticulum stress and its associated diseases
-
Bhandary B, Marahatta A, Kim HR, Chae HJ (2012) An involvement of oxidative stress in endoplasmic reticulum stress and its associated diseases. Int J Mol Sci 14(1):434-456.
-
(2012)
Int J Mol Sci
, vol.14
, Issue.1
, pp. 434-456
-
-
Bhandary, B.1
Marahatta, A.2
Kim, H.R.3
Chae, H.J.4
-
30
-
-
84867773087
-
Mitophagy: Mechanisms, pathophysiological roles, and analysis
-
Ding WX, Yin XM (2012) Mitophagy: Mechanisms, pathophysiological roles, and analysis. Biol Chem 393(7):547-564.
-
(2012)
Biol Chem
, vol.393
, Issue.7
, pp. 547-564
-
-
Ding, W.X.1
Yin, X.M.2
-
31
-
-
77649275621
-
ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function
-
Pi J, et al. (2010) ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function. Toxicol Appl Pharmacol 244(1):77-83.
-
(2011)
Toxicol Appl Pharmacol
, vol.244
, Issue.1
, pp. 77-83
-
-
Pi, J.1
-
32
-
-
1942455887
-
Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles
-
Itoh K, Tong KI, Yamamoto M (2004) Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles. Free Radic Biol Med 36(10):1208-1213.
-
(2004)
Free Radic Biol Med
, vol.36
, Issue.10
, pp. 1208-1213
-
-
Itoh, K.1
Tong, K.I.2
Yamamoto, M.3
-
33
-
-
84922489435
-
Oxidative stress and autophagy: The clash between damage and metabolic needs
-
Filomeni G, De Zio D, Cecconi F (2015) Oxidative stress and autophagy: the clash between damage and metabolic needs. Cell Death Differ 22(3):377-388.
-
(2015)
Cell Death Differ
, vol.22
, Issue.3
, pp. 377-388
-
-
Filomeni, G.1
De Zio, D.2
Cecconi, F.3
-
35
-
-
84922801415
-
Regeneration and repair of the exocrine pancreas
-
Murtaugh LC, Keefe MD (2015) Regeneration and repair of the exocrine pancreas. Annu Rev Physiol 77:229-249.
-
(2015)
Annu Rev Physiol
, vol.77
, pp. 229-249
-
-
Murtaugh, L.C.1
Keefe, M.D.2
-
36
-
-
84880436692
-
The plastic pancreas
-
Ziv O, Glaser B, Dor Y (2013) The plastic pancreas. Dev Cell 26(1):3-7.
-
(2013)
Dev Cell
, vol.26
, Issue.1
, pp. 3-7
-
-
Ziv, O.1
Glaser, B.2
Dor, Y.3
-
37
-
-
37649023286
-
Matrix metalloproteinase 7 controls pancreatic acinar cell transdifferentiation by activating the Notch signaling pathway
-
Sawey ET, Johnson JA, Crawford HC (2007) Matrix metalloproteinase 7 controls pancreatic acinar cell transdifferentiation by activating the Notch signaling pathway. Proc Natl Acad Sci USA 104(49):19327-19332.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.49
, pp. 19327-19332
-
-
Sawey, E.T.1
Johnson, J.A.2
Crawford, H.C.3
-
38
-
-
0037058574
-
Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK
-
Yan W, et al. (2002) Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK. Proc Natl Acad Sci USA 99(25): 15920-15925.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.25
, pp. 15920-15925
-
-
Yan, W.1
-
39
-
-
84905049169
-
Calcium trafficking integrates endoplasmic reticulum function with mitochondrial bioenergetics
-
Kaufman RJ, Malhotra JD (2014) Calcium trafficking integrates endoplasmic reticulum function with mitochondrial bioenergetics. Biochim Biophys Acta 1843(10): 2233-2239.
-
(2014)
Biochim Biophys Acta
, vol.1843
, Issue.10
, pp. 2233-2239
-
-
Kaufman, R.J.1
Malhotra, J.D.2
-
40
-
-
24944487996
-
Pancreas-specific deletion of beta-catenin reveals Wnt-dependent and Wnt-independent functions during development
-
Dessimoz J, Bonnard C, Huelsken J, Grapin-Botton A (2005) Pancreas-specific deletion of beta-catenin reveals Wnt-dependent and Wnt-independent functions during development. Curr Biol 15(18):1677-1683.
-
(2005)
Curr Biol
, vol.15
, Issue.18
, pp. 1677-1683
-
-
Dessimoz, J.1
Bonnard, C.2
Huelsken, J.3
Grapin-Botton, A.4
-
41
-
-
84873842067
-
P62 links β-Adrenergic input to mitochondrial function and thermogenesis
-
Muller TD, et al. (2013) p62 links β-Adrenergic input to mitochondrial function and thermogenesis. J Clin Invest 123(1):469-478.
-
(2013)
J Clin Invest
, vol.123
, Issue.1
, pp. 469-478
-
-
Muller, T.D.1
-
42
-
-
9144266295
-
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
-
Hingorani SR, et al. (2003) Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell 4(6):437-450.
-
(2003)
Cancer Cell
, vol.4
, Issue.6
, pp. 437-450
-
-
Hingorani, S.R.1
-
43
-
-
77951737783
-
Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations
-
Chen H, et al. (2010) Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations. Cell 141(2):280-289.
-
(2011)
Cell
, vol.141
, Issue.2
, pp. 280-289
-
-
Chen, H.1
-
44
-
-
0035710746
-
Analysis of relative gene expression data using realtime quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using realtime quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25(4):402-408.
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
|