메뉴 건너뛰기




Volumn 39, Issue , 2017, Pages 220-227

Literature mining supports a next-generation modeling approach to predict cellular byproduct secretion

Author keywords

Constraint based modeling; Escherichia coli; Genome scale model; Literature mining; ME model

Indexed keywords

BYPRODUCTS; ESCHERICHIA COLI; FORECASTING; GENE EXPRESSION; GENES; METABOLISM;

EID: 85007574032     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2016.12.004     Document Type: Article
Times cited : (30)

References (64)
  • 1
    • 38049001166 scopus 로고    scopus 로고
    • Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels
    • Atsumi, S., Hanai, T., Liao, J.C., Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels. Nature 451 (2008), 86–89.
    • (2008) Nature , vol.451 , pp. 86-89
    • Atsumi, S.1    Hanai, T.2    Liao, J.C.3
  • 2
    • 74149094503 scopus 로고    scopus 로고
    • Engineering the isobutanol biosynthetic pathway in Escherichia coli by comparison of three aldehyde reductase/alcohol dehydrogenase genes
    • Atsumi, S., Wu, T.Y., Eckl, E.M., Hawkins, S.D., Buelter, T., Liao, J.C., Engineering the isobutanol biosynthetic pathway in Escherichia coli by comparison of three aldehyde reductase/alcohol dehydrogenase genes. Appl. Microbiol. Biotechnol. 85 (2010), 651–657.
    • (2010) Appl. Microbiol. Biotechnol. , vol.85 , pp. 651-657
    • Atsumi, S.1    Wu, T.Y.2    Eckl, E.M.3    Hawkins, S.D.4    Buelter, T.5    Liao, J.C.6
  • 3
    • 79958097953 scopus 로고    scopus 로고
    • The moderately efficient enzyme: evolutionary and physicochemical trends shaping enzyme parameters
    • Bar-Even, A., Noor, E., Savir, Y., The moderately efficient enzyme: evolutionary and physicochemical trends shaping enzyme parameters. Biochemistry, 2011, 4402–4410.
    • (2011) Biochemistry , pp. 4402-4410
    • Bar-Even, A.1    Noor, E.2    Savir, Y.3
  • 4
    • 84963638638 scopus 로고    scopus 로고
    • Overflow metabolism in bacteria results from efficient proteome allocation for energy biogenesis
    • Basan, M., Hui, S., Zhang, Z., Shen, Y., Williamson, J.R., Hwa, T., Overflow metabolism in bacteria results from efficient proteome allocation for energy biogenesis. Nature, 2015.
    • (2015) Nature
    • Basan, M.1    Hui, S.2    Zhang, Z.3    Shen, Y.4    Williamson, J.R.5    Hwa, T.6
  • 5
    • 77955716950 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli for the production of succinate from glycerol
    • Blankschien, M.D., Clomburg, J.M., Gonzalez, R., Metabolic engineering of Escherichia coli for the production of succinate from glycerol. Metab. Eng. 12 (2010), 409–419.
    • (2010) Metab. Eng. , vol.12 , pp. 409-419
    • Blankschien, M.D.1    Clomburg, J.M.2    Gonzalez, R.3
  • 6
    • 84892788440 scopus 로고    scopus 로고
    • Constraint-based models predict metabolic and associated cellular functions
    • Bordbar, A., Monk, J.M., King, Z.A., Palsson, B.O., Constraint-based models predict metabolic and associated cellular functions. Nat. Rev. Genet. 15 (2014), 107–120.
    • (2014) Nat. Rev. Genet. , vol.15 , pp. 107-120
    • Bordbar, A.1    Monk, J.M.2    King, Z.A.3    Palsson, B.O.4
  • 7
    • 0242487787 scopus 로고    scopus 로고
    • Optknock: a bilevel programming framework for identifying gene knockout strategies for microbial strain optimization
    • Burgard, A.P., Pharkya, P., Maranas, C.D., Optknock: a bilevel programming framework for identifying gene knockout strategies for microbial strain optimization. Biotechnol. Bioeng. 84 (2003), 647–657.
    • (2003) Biotechnol. Bioeng. , vol.84 , pp. 647-657
    • Burgard, A.P.1    Pharkya, P.2    Maranas, C.D.3
  • 8
    • 84896444385 scopus 로고    scopus 로고
    • Stringent response of Escherichia coli: revisiting the bibliome using literature mining
    • Carneiro, S., Lourenço, A., Ferreira, E.C., Rocha, I., Stringent response of Escherichia coli: revisiting the bibliome using literature mining. Microb. Inform. Exp., 1, 2011, 14.
    • (2011) Microb. Inform. Exp. , vol.1 , pp. 14
    • Carneiro, S.1    Lourenço, A.2    Ferreira, E.C.3    Rocha, I.4
  • 9
    • 84927537676 scopus 로고    scopus 로고
    • Synthetic biologists seek standards for nascent field
    • Check Hayden, E., Synthetic biologists seek standards for nascent field. Nat. News, 520, 2015, 141.
    • (2015) Nat. News , vol.520 , pp. 141
    • Check Hayden, E.1
  • 11
    • 0024723183 scopus 로고
    • The fermentation pathways of Escherichia coli
    • Clark, David P., The fermentation pathways of Escherichia coli. FEMS Microbiol. Rev. 63 (1989), 223–234.
    • (1989) FEMS Microbiol. Rev. , vol.63 , pp. 223-234
    • Clark, D.P.1
  • 12
    • 80051941601 scopus 로고    scopus 로고
    • Engineered reversal of the β-oxidation cycle for the synthesis of fuels and chemicals
    • Dellomonaco, C., Clomburg, J.M., Miller, E.N., Gonzalez, R., Engineered reversal of the β-oxidation cycle for the synthesis of fuels and chemicals. Nature 476 (2011), 355–359.
    • (2011) Nature , vol.476 , pp. 355-359
    • Dellomonaco, C.1    Clomburg, J.M.2    Miller, E.N.3    Gonzalez, R.4
  • 13
    • 0031856455 scopus 로고    scopus 로고
    • A novel fermentation pathway in an Escherichia coli mutant producing succinic acid, acetic acid, and ethanol
    • Donnelly, M.I., Millard, C.S., Clark, D.P., Chen, M.J., Rathke, J.W., A novel fermentation pathway in an Escherichia coli mutant producing succinic acid, acetic acid, and ethanol. Appl. Biochem. Biotechnol. 70 (1998), 187–198.
    • (1998) Appl. Biochem. Biotechnol. , vol.70 , pp. 187-198
    • Donnelly, M.I.1    Millard, C.S.2    Clark, D.P.3    Chen, M.J.4    Rathke, J.W.5
  • 15
    • 84881152495 scopus 로고    scopus 로고
    • COBRApy: constraints-based reconstruction and analysis for python
    • Ebrahim, A., Lerman, J.A., Palsson, B.O., Hyduke, D.R., COBRApy: constraints-based reconstruction and analysis for python. BMC Syst. Biol., 7, 2013, 74.
    • (2013) BMC Syst. Biol. , vol.7 , pp. 74
    • Ebrahim, A.1    Lerman, J.A.2    Palsson, B.O.3    Hyduke, D.R.4
  • 16
    • 0035125986 scopus 로고    scopus 로고
    • In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data
    • Edwards, J.S., Ibarra, R.U., Palsson, B.O., In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data. Nat. Biotechnol. 19 (2001), 125–130.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 125-130
    • Edwards, J.S.1    Ibarra, R.U.2    Palsson, B.O.3
  • 18
    • 77950863401 scopus 로고    scopus 로고
    • Model-driven evaluation of the production potential for growth-coupled products of Escherichia coli
    • Feist, A.M., Zielinski, D.C., Orth, J.D., Schellenberger, J., Herrgård, M.J., Palsson, B.O., Model-driven evaluation of the production potential for growth-coupled products of Escherichia coli. Metab. Eng. 12 (2010), 173–186.
    • (2010) Metab. Eng. , vol.12 , pp. 173-186
    • Feist, A.M.1    Zielinski, D.C.2    Orth, J.D.3    Schellenberger, J.4    Herrgård, M.J.5    Palsson, B.O.6
  • 20
    • 84961140736 scopus 로고    scopus 로고
    • Quantitative feature extraction from the chinese hamster ovary bioprocess bibliome using a novel meta-analysis workflow
    • Golabgir, A., Gutierrez, J.M., Hefzi, H., Li, S., Palsson, B.O., Herwig, C., Lewis, N.E., Quantitative feature extraction from the chinese hamster ovary bioprocess bibliome using a novel meta-analysis workflow. Biotechnol. Adv. 34 (2016), 621–633.
    • (2016) Biotechnol. Adv. , vol.34 , pp. 621-633
    • Golabgir, A.1    Gutierrez, J.M.2    Hefzi, H.3    Li, S.4    Palsson, B.O.5    Herwig, C.6    Lewis, N.E.7
  • 22
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan, D., Weinberg, R.A., Hallmarks of cancer: the next generation. Cell 144 (2011), 646–674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 23
    • 0037079023 scopus 로고    scopus 로고
    • Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth
    • Ibarra, R.U., Edwards, J.S., Palsson, B.O., Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth. Nature 420 (2002), 20–23.
    • (2002) Nature , vol.420 , pp. 20-23
    • Ibarra, R.U.1    Edwards, J.S.2    Palsson, B.O.3
  • 25
    • 80155212672 scopus 로고    scopus 로고
    • Carbohydrate-active enzymes exemplify entropic principles in metabolism
    • Kartal, O., Mahlow, S., Skupin, A., Ebenhöh, O., Carbohydrate-active enzymes exemplify entropic principles in metabolism. Mol. Syst. Biol., 7, 2011, 542.
    • (2011) Mol. Syst. Biol. , vol.7 , pp. 542
    • Kartal, O.1    Mahlow, S.2    Skupin, A.3    Ebenhöh, O.4
  • 26
    • 84940751701 scopus 로고    scopus 로고
    • Escher: a web application for building, sharing, and embedding data-rich visualizations of biological pathways
    • King, Z.A., Dräger, A., Ebrahim, A., Sonnenschein, N., Lewis, N.E., Palsson, B.O., Escher: a web application for building, sharing, and embedding data-rich visualizations of biological pathways. PLoS Comput. Biol., 11, 2015, e1004321.
    • (2015) PLoS Comput. Biol. , vol.11 , pp. e1004321
    • King, Z.A.1    Dräger, A.2    Ebrahim, A.3    Sonnenschein, N.4    Lewis, N.E.5    Palsson, B.O.6
  • 30
    • 29144484729 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli for enhanced production of succinic acid, based on genome comparison and in silico gene knockout simulation
    • Lee, S.J., Lee, D.Y., Kim, T.Y., Kim, B.H., Lee, J., Lee, S.Y., Metabolic engineering of Escherichia coli for enhanced production of succinic acid, based on genome comparison and in silico gene knockout simulation. Appl. Environ. Microbiol., 71, 2005, 7880.
    • (2005) Appl. Environ. Microbiol. , vol.71 , pp. 7880
    • Lee, S.J.1    Lee, D.Y.2    Kim, T.Y.3    Kim, B.H.4    Lee, J.5    Lee, S.Y.6
  • 31
    • 0010407860 scopus 로고    scopus 로고
    • Bacterial polyhydroxyalkanoates
    • Lee, S.Y., Bacterial polyhydroxyalkanoates. Biotechnol. Bioeng. 49 (1996), 1–14.
    • (1996) Biotechnol. Bioeng. , vol.49 , pp. 1-14
    • Lee, S.Y.1
  • 32
    • 84943604629 scopus 로고    scopus 로고
    • Systems strategies for developing industrial microbial strains
    • Lee, S.Y., Kim, H.U., Systems strategies for developing industrial microbial strains. Nat. Biotechnol. 33 (2015), 1061–1072.
    • (2015) Nat. Biotechnol. , vol.33 , pp. 1061-1072
    • Lee, S.Y.1    Kim, H.U.2
  • 35
    • 84858439602 scopus 로고    scopus 로고
    • Constraining the metabolic genotype-phenotype relationship using a phylogeny of in silico methods
    • Lewis, N.E., Nagarajan, H., Palsson, B.Ø., Constraining the metabolic genotype-phenotype relationship using a phylogeny of in silico methods. Nat. Rev. Microbiol. 10 (2012), 291–305.
    • (2012) Nat. Rev. Microbiol. , vol.10 , pp. 291-305
    • Lewis, N.E.1    Nagarajan, H.2    Palsson, B.Ø.3
  • 36
    • 84880514779 scopus 로고    scopus 로고
    • Enhancement of succinate production by metabolically engineered Escherichia coli with co-expression of nicotinic acid phosphoribosyltransferase and pyruvate carboxylase
    • Ma, J., Gou, D., Liang, L., Liu, R., Chen, X., Zhang, C., Zhang, J., Chen, K., Jiang, M., Enhancement of succinate production by metabolically engineered Escherichia coli with co-expression of nicotinic acid phosphoribosyltransferase and pyruvate carboxylase. Appl. Microbiol. Biotechnol., 2013.
    • (2013) Appl. Microbiol. Biotechnol.
    • Ma, J.1    Gou, D.2    Liang, L.3    Liu, R.4    Chen, X.5    Zhang, C.6    Zhang, J.7    Chen, K.8    Jiang, M.9
  • 37
    • 0031766842 scopus 로고    scopus 로고
    • Anaerobic expression of Escherichia coli succinate dehydrogenase: functional replacement of fumarate reductase in the respiratory chain during anaerobic growth
    • Maklashina, E., Berthold, D.a., Cecchini, G., Anaerobic expression of Escherichia coli succinate dehydrogenase: functional replacement of fumarate reductase in the respiratory chain during anaerobic growth. J. Bacteriol. 180 (1998), 5989–5996.
    • (1998) J. Bacteriol. , vol.180 , pp. 5989-5996
    • Maklashina, E.1    Berthold, D.A.2    Cecchini, G.3
  • 39
    • 73149109962 scopus 로고    scopus 로고
    • Shifts in growth strategies reflect tradeoffs in cellular economics
    • Molenaar, D., van Berlo, R., de Ridder, D., Teusink, B., Shifts in growth strategies reflect tradeoffs in cellular economics. Mol. Syst. Biol., 5, 2009, 323.
    • (2009) Mol. Syst. Biol. , vol.5 , pp. 323
    • Molenaar, D.1    van Berlo, R.2    de Ridder, D.3    Teusink, B.4
  • 41
    • 84885367114 scopus 로고    scopus 로고
    • Genome-scale models of metabolism and gene expression extend and refine growth phenotype prediction
    • O'Brien, E.J., Lerman, J.A., Chang, R.L., Hyduke, D.R., Palsson, B.Ø., Genome-scale models of metabolism and gene expression extend and refine growth phenotype prediction. Mol. Syst. Biol., 9, 2013, 693.
    • (2013) Mol. Syst. Biol. , vol.9 , pp. 693
    • O'Brien, E.J.1    Lerman, J.A.2    Chang, R.L.3    Hyduke, D.R.4    Palsson, B.Ø.5
  • 42
    • 84920923824 scopus 로고    scopus 로고
    • Computing the functional proteome: recent progress and future prospects for genome-scale models
    • O'Brien, E.J., Palsson, B.O., Computing the functional proteome: recent progress and future prospects for genome-scale models. Curr. Opin. Biotechnol. 34 (2015), 125–134.
    • (2015) Curr. Opin. Biotechnol. , vol.34 , pp. 125-134
    • O'Brien, E.J.1    Palsson, B.O.2
  • 45
    • 84923570019 scopus 로고    scopus 로고
    • Systems Biology: Properties of Reconstructed Networks
    • Cambridge University Press Cambridge, UK
    • Palsson, B.Ø., Systems Biology: Properties of Reconstructed Networks. 2006, Cambridge University Press, Cambridge, UK.
    • (2006)
    • Palsson, B.Ø.1
  • 47
    • 0344328817 scopus 로고    scopus 로고
    • An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR)
    • Reed, J.L., Vo, T.D., Schilling, C.H., Palsson, B.Ø., An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR). Genome Biol., 4, 2003, R54.
    • (2003) Genome Biol. , vol.4 , pp. R54
    • Reed, J.L.1    Vo, T.D.2    Schilling, C.H.3    Palsson, B.Ø.4
  • 48
    • 16444375254 scopus 로고    scopus 로고
    • Efficient succinic acid production from glucose through overexpression of pyruvate carboxylase in an Escherichia coli alcohol dehydrogenase and lactate dehydrogenase mutant
    • Sánchez, A.M., Bennett, G.N., San, K.Y., Efficient succinic acid production from glucose through overexpression of pyruvate carboxylase in an Escherichia coli alcohol dehydrogenase and lactate dehydrogenase mutant. Biotechnol. Prog. 21 (2005), 358–365.
    • (2005) Biotechnol. Prog. , vol.21 , pp. 358-365
    • Sánchez, A.M.1    Bennett, G.N.2    San, K.Y.3
  • 49
    • 18944378749 scopus 로고    scopus 로고
    • Novel pathway engineering design of the anaerobic central metabolic pathway in Escherichia coli to increase succinate yield and productivity
    • Sánchez, A.M., Bennett, G.N., San, K.Y., Novel pathway engineering design of the anaerobic central metabolic pathway in Escherichia coli to increase succinate yield and productivity. Metab. Eng. 7 (2005), 229–239.
    • (2005) Metab. Eng. , vol.7 , pp. 229-239
    • Sánchez, A.M.1    Bennett, G.N.2    San, K.Y.3
  • 50
    • 34447523907 scopus 로고    scopus 로고
    • Systematic evaluation of objective functions for predicting intracellular fluxes in Escherichia coli
    • Schuetz, R., Kuepfer, L., Sauer, U., Systematic evaluation of objective functions for predicting intracellular fluxes in Escherichia coli. Mol. Syst. Biol., 3, 2007, 119.
    • (2007) Mol. Syst. Biol. , vol.3 , pp. 119
    • Schuetz, R.1    Kuepfer, L.2    Sauer, U.3
  • 51
    • 78650595035 scopus 로고    scopus 로고
    • Manipulating redox and ATP balancing for improved production of succinate in E. coli
    • Singh, A., Cher Soh, K., Hatzimanikatis, V., Gill, R.T., Manipulating redox and ATP balancing for improved production of succinate in E. coli. Metab. Eng. 13 (2011), 76–81.
    • (2011) Metab. Eng. , vol.13 , pp. 76-81
    • Singh, A.1    Cher Soh, K.2    Hatzimanikatis, V.3    Gill, R.T.4
  • 52
    • 0030752053 scopus 로고    scopus 로고
    • +-dependent malic enzyme in an Escherichia coli mutant
    • +-dependent malic enzyme in an Escherichia coli mutant. Appl. Environ. Microbiol. 63 (1997), 2695–2701.
    • (1997) Appl. Environ. Microbiol. , vol.63 , pp. 2695-2701
    • Stols, L.1    Donnelly, M.I.2
  • 53
    • 0031085246 scopus 로고    scopus 로고
    • Expression of ascaris suum malic enzyme in a mutant Escherichia coli allows production of succinic acid from glucose
    • Stols, L., Kulkarni, G., Harris, B.G., Donnelly, M.I., Expression of ascaris suum malic enzyme in a mutant Escherichia coli allows production of succinic acid from glucose. Appl. Biochem. Biotechnol. 63–65 (1997), 153–158.
    • (1997) Appl. Biochem. Biotechnol. , vol.63-65 , pp. 153-158
    • Stols, L.1    Kulkarni, G.2    Harris, B.G.3    Donnelly, M.I.4
  • 54
    • 79961084093 scopus 로고    scopus 로고
    • Redesigning Escherichia coli metabolism for anaerobic production of isobutanol
    • Trinh, C.T., Li, J., Blanch, H.W., Clark, D.S., Redesigning Escherichia coli metabolism for anaerobic production of isobutanol. Appl. Environ. Microbiol. 77 (2011), 4894–4904.
    • (2011) Appl. Environ. Microbiol. , vol.77 , pp. 4894-4904
    • Trinh, C.T.1    Li, J.2    Blanch, H.W.3    Clark, D.S.4
  • 55
    • 0027223982 scopus 로고
    • Stoichiometric interpretation of Escherichia coli glucose catabolism under various oxygenation rates
    • Varma, A., Boesch, B.W., Palsson, B.O., Stoichiometric interpretation of Escherichia coli glucose catabolism under various oxygenation rates. Appl. Environ. Microbiol. 59 (1993), 2465–2473.
    • (1993) Appl. Environ. Microbiol. , vol.59 , pp. 2465-2473
    • Varma, A.1    Boesch, B.W.2    Palsson, B.O.3
  • 56
    • 0036210809 scopus 로고    scopus 로고
    • Effects of growth mode and pyruvate carboxylase on succinic acid production by metabolically engineered strains of Escherichia coli
    • Vemuri, G.N., Eiteman, M.A., Altman, E., Effects of growth mode and pyruvate carboxylase on succinic acid production by metabolically engineered strains of Escherichia coli. Appl. Environ. Microbiol. 68 (2002), 1715–1727.
    • (2002) Appl. Environ. Microbiol. , vol.68 , pp. 1715-1727
    • Vemuri, G.N.1    Eiteman, M.A.2    Altman, E.3
  • 57
    • 84934927409 scopus 로고    scopus 로고
    • The LASER database: formalizing design rules for metabolic engineering
    • Winkler, J.D., Halweg-Edwards, A.L., Gill, R.T., The LASER database: formalizing design rules for metabolic engineering. Metab. Eng. Commun. 2 (2015), 30–38.
    • (2015) Metab. Eng. Commun. , vol.2 , pp. 30-38
    • Winkler, J.D.1    Halweg-Edwards, A.L.2    Gill, R.T.3
  • 58
    • 84964774521 scopus 로고    scopus 로고
    • Rapid prediction of bacterial heterotrophic fluxomics using machine learning and constraint programming
    • Wu, S.G., Wang, Y., Jiang, W., Oyetunde, T., Yao, R., Zhang, X., Shimizu, K., Tang, Y.J., Bao, F.S., Rapid prediction of bacterial heterotrophic fluxomics using machine learning and constraint programming. PLoS Comput. Biol., 12, 2016, e1004838.
    • (2016) PLoS Comput. Biol. , vol.12 , pp. e1004838
    • Wu, S.G.1    Wang, Y.2    Jiang, W.3    Oyetunde, T.4    Yao, R.5    Zhang, X.6    Shimizu, K.7    Tang, Y.J.8    Bao, F.S.9
  • 60
    • 80052647009 scopus 로고    scopus 로고
    • Metabolic engineering of microbial pathways for advanced biofuels production
    • Zhang, F., Rodriguez, S., Keasling, J.D., Metabolic engineering of microbial pathways for advanced biofuels production. Curr. Opin. Biotechnol. 22 (2011), 775–783.
    • (2011) Curr. Opin. Biotechnol. , vol.22 , pp. 775-783
    • Zhang, F.1    Rodriguez, S.2    Keasling, J.D.3
  • 62
    • 77950580812 scopus 로고    scopus 로고
    • Fermentation of glycerol to succinate by metabolically engineered strains of Escherichia coli
    • Zhang, X., Shanmugam, K.T., Ingram, L.O., Fermentation of glycerol to succinate by metabolically engineered strains of Escherichia coli. Appl. Environ. Microbiol. 76 (2010), 2397–2401.
    • (2010) Appl. Environ. Microbiol. , vol.76 , pp. 2397-2401
    • Zhang, X.1    Shanmugam, K.T.2    Ingram, L.O.3
  • 64
    • 0037394933 scopus 로고    scopus 로고
    • Functional replacement of the Escherichia coli d-(-)-lactate dehydrogenase gene (ldha) with the l-(+)-lactate dehydrogenase gene (ldhl) from pediococcus acidilactici
    • Zhou, S., Shanmugam, K.T., Ingram, L.O., Functional replacement of the Escherichia coli d-(-)-lactate dehydrogenase gene (ldha) with the l-(+)-lactate dehydrogenase gene (ldhl) from pediococcus acidilactici. Appl. Environ. Microbiol., 69, 2003, 2237.
    • (2003) Appl. Environ. Microbiol. , vol.69 , pp. 2237
    • Zhou, S.1    Shanmugam, K.T.2    Ingram, L.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.