Next-generation genome-scale models for metabolic engineering

Current Opinion in Biotechnology

Volumn 35, Issue , 2015, Pages 23-29

  King, Zachary A ^a   Lloyd, Colton J ^a   Feist, Adam M ^a,b   Palsson, Bernhard O ^a,b,c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b Chalmers University of Technology   (Denmark)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOINFORMATICS; CHEMICAL MODIFICATION; FORECASTING; GENES; METABOLISM;

BIOLOGICAL PROCESS; CHEMICAL PRODUCTION; GENETIC MODIFICATIONS; GENOME-SCALE MODEL; METABOLIC NETWORK; SIMULATION STRATEGIES; STRAIN OPTIMIZATION; SYSTEMS METABOLIC ENGINEERINGS;

METABOLIC ENGINEERING;

GLUCOSE; PALMITIC ACID; PENTOSE PHOSPHATE; PROPANOL; XYLOSE;

ALGORITHM; ALLOSTERISM; ANALYTICAL PARAMETERS; BIOMASS PRODUCTION; CELLULAR DISTRIBUTION; COMPUTER MODEL; COMPUTER SIMULATION; CONSTRAINT BASED RECONSTRUCTION AND ANALYSIS MODEL; DNA MODIFICATION; DOWN REGULATION; ESCHERICHIA COLI; FATTY ACID SYNTHESIS; GEM PRO MODEL; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC STRAIN; METABOLIC ENGINEERING; METABOLISM MODEL; METABOLISM WITH GENE EXPRESSION MODEL; MICROBIAL PRODUCTION STRAIN; MODULAR SIMULATION; NONHUMAN; PREDICTIVE VALUE; PROBABILISTIC REGULATION OF METABOLISM MODEL; PROCESS DESIGN; PROCESS OPTIMIZATION; PROTEIN LOCALIZATION; REVIEW; SIMUP ALGORITHM; STOICHIOMETRY; STRAIN IDENTIFICATION; SYSTEMS BIOLOGY; THEORETICAL YIELD; THERMOTOGA MARITIMA; TRANSCRIPTION REGULATION; UPREGULATION; WHOLE CELL MODEL; BIOLOGICAL MODEL; BIOMASS; GENOME; HUMAN; METABOLISM;

BIOMASS; GENE DELETION; GENOME; HUMANS; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; MODELS, BIOLOGICAL;

EID: 84920896587     PISSN: 09581669     EISSN: 18790429     Source Type: Journal    
DOI: 10.1016/j.copbio.2014.12.016     Document Type: Review

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