Model-driven discovery of underground metabolic functions in Escherichia coli

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 3, 2015, Pages 929-934

  Guzmán, Gabriela I ^a   Utrilla, José ^a   Nurk, Sergey ^b   Brunk, Elizabeth ^c   Monk, Jonathan M ^d   Ebrahim, Ali ^a   Palsson, Bernhard O ^a,e,f   Feist, Adam M ^a,e  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b ST PETERSBURG ACADEMIC UNIVERSITY   (Russian Federation)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e Chalmers University of Technology   (Denmark)

^f UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Genome scale modeling; Isozyme discovery; Substrate promiscuity; Systems biology; Underground metabolism

Indexed keywords

AMINOTRANSFERASE; BACTERIAL ENZYME; CITRATE SYNTHASE; ISOENZYME;

AMINO ACID SEQUENCE; AMINO ACID SYNTHESIS; ARGD GENE; ARTICLE; ASPC GENE; ASTC GENE; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL METABOLISM; BACTERIAL STRAIN; CROSS REACTION; DNA BINDING; ENZYME SUBSTRATE; ESCHERICHIA COLI; GABT GENE; GLTA GENE; ISOENZYME ANALYSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PRPC GENE; PUUE GENE; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; SEQUENCE HOMOLOGY; TYRB GENE; UPREGULATION; BIOLOGICAL MODEL; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM;

ESCHERICHIA COLI;

ESCHERICHIA COLI; GENOME, BACTERIAL; MODELS, BIOLOGICAL;

EID: 84921340441     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1414218112     Document Type: Article

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