Model-driven evaluation of the production potential for growth-coupled products of Escherichia coli

Metabolic Engineering

Volumn 12, Issue 3, 2010, Pages 173-186

  Feist, Adam M ^a   Zielinski, Daniel C ^a   Orth, Jeffrey D ^a   Schellenberger, Jan ^b   Herrgard, Markus J ^a   Palsson, Bernhard Ø ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Escherichia coli; Metabolism; OptGene; OptKnock; Systems biology

Indexed keywords

AEROBIC AND ANAEROBIC CONDITIONS; BACTERIAL PRODUCTION; DIFFERENT SUBSTRATES; E. COLI; IN-SILICO; INTEGRATED APPROACH; METABOLIC ENGINEERING; METABOLITE PRODUCTION; MODEL-DRIVEN; NEW CONCEPT; OBJECTIVE FUNCTIONS; OPTGENE; PRODUCTION STRAIN; REACTION ELIMINATION; SPECIFIC PRODUCTIVITY; SYSTEMATIC MODELS; SYSTEMS BIOLOGY;

AMINO ACIDS; DESIGN; ESCHERICHIA COLI; INTEGRATED CONTROL; METABOLISM; ORGANIC ACIDS;

SUBSTRATES;

2 OXOGLUTARIC ACID; ALANINE; ALCOHOL; FUMARIC ACID; GLUCOSE; GLUTAMIC ACID; GLYCEROL; LACTIC ACID; MALIC ACID; PYRUVIC ACID; SERINE; SUCCINIC ACID; XYLOSE;

AEROBIC METABOLISM; ANAEROBIC METABOLISM; ARTICLE; BACTERIAL METABOLISM; BACTERIAL STRAIN; CONTROLLED STUDY; ESCHERICHIA COLI; GROWTH RATE; METABOLIC ENGINEERING; METABOLITE; NONHUMAN; PRIORITY JOURNAL; SYSTEMS BIOLOGY;

BACTERIA; BIOLOGICAL PROCESSES; ESCHERICHIA COLI; GROWTH; MODELS, BIOLOGICAL; RISK FACTORS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 77950863401     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2009.10.003     Document Type: Article

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