Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice

BMC Genomics

Volumn 17, Issue 1, 2016, Pages

  Leist, Sarah R ^a   Pilzner, Carolin ^a   van den Brand, Judith M A ^b   Dengler, Leonie ^a   Geffers, Robert ^c   Kuiken, Thijs ^b   Balling, Rudi ^d   Kollmus, Heike ^a   Schughart, Klaus ^a,e  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^d UNIVERSITY OF LUXEMBOURG   (Luxembourg)

^e UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Collaborative cross; Immune response; Influenza susceptibility; Mouse model; Phenotyping

Indexed keywords

A J MOUSE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; COLLABORATIVE CROSS FOUNDER MOUSE; CONTROLLED STUDY; DEATH; DISEASE SEVERITY; EIJ MOUSE; FEMALE; GENDER; GENETIC ASSOCIATION; GENETIC BACKGROUND; GRANULOCYTE; HERITABILITY; HISTOPATHOLOGY; IMMUNE RESPONSE; INFECTION SENSITIVITY; INFLUENZA A (H3N2); LEUKOCYTE COUNT; LEUKOCYTE MIGRATION; LUNG ALVEOLUS MACROPHAGE; LUNG WEIGHT; LYMPHOCYTE COUNT; MONOCYTE; MOUSE; MOUSE STRAIN; NONHUMAN; NONOBESE DIABETIC MOUSE; NZO MOUSE; PHENOTYPE; PWK MOUSE; STRAIN DIFFERENCE; SURVIVAL RATE; SVIMJ MOUSE; TRANSCRIPTOMICS; VIRUS LOAD; WEIGHT REDUCTION; 129 MOUSE; ANIMAL; BODY WEIGHT; C57BL MOUSE; DISEASE RESISTANCE; GENETICS; INBRED MOUSE STRAIN; INFLUENZA A VIRUS (H3N2); LUNG; MALE; ORTHOMYXOVIRUS INFECTION; PATHOLOGY; VIROLOGY;

TRANSCRIPTOME;

ANIMALS; BODY WEIGHT; DISEASE RESISTANCE; FEMALE; INFLUENZA A VIRUS, H3N2 SUBTYPE; LUNG; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, INBRED STRAINS; ORTHOMYXOVIRIDAE INFECTIONS; PHENOTYPE; TRANSCRIPTOME; VIRAL LOAD;

EID: 85007554499     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-016-2483-y     Document Type: Article

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