Structural requirements for the antiviral activity of the human MxA protein against Thogoto and influenza A virus

Journal of Biological Chemistry

Volumn 289, Issue 9, 2014, Pages 6020-6027

  Patzina, Corinna ^a   Haller, Otto ^a   Kochs, Georg ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRAL ACTIVITIES; INFLUENZA A VIRUS; KEY DETERMINANTS; MUTATIONAL ANALYSIS; STRUCTURAL ELEMENTS; STRUCTURAL FUNCTION; STRUCTURAL REQUIREMENTS; TARGET RECOGNITION;

AMINO ACIDS; PROTEINS;

VIRUSES;

ALANINE; GLUTAMIC ACID; MYXOVIRUS RESISTANCE PROTEIN A; PROTEIN L4; UNCLASSIFIED DRUG; VIRUS NUCLEOPROTEIN; VIRUS PROTEIN;

ALPHA HELIX; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANTIVIRAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; INFLUENZA VIRUS A; LA CROSSE VIRUS; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOMYXOVIRUS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; VIRUS REPLICATION;

ANTIVIRAL AGENTS; DYNAMIN; GTPASE; INFLUENZA VIRUS; INNATE IMMUNITY; INTERFERON; MXA; MYXOVIRUS RESISTANCE;

AMINO ACID MOTIFS; ANIMALS; CERCOPITHECUS AETHIOPS; HUMANS; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA, HUMAN; MUTATION; MYXOVIRUS RESISTANCE PROTEINS; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; THOGOTOVIRUS;

EID: 84896877632     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.543892     Document Type: Article

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