Induction of interleukin-1 beta (IL-1β) is a critical component of lung inflammation during influenza A (H1N1) virus infection

Journal of Medical Virology

Volumn 87, Issue 7, 2015, Pages 1104-1112

  Kim, Kwang Seok ^a   Jung, Hyemin ^a   Shin, In Kyung ^a   Choi, Bo Ra ^a   Kim, Dong Ho ^a  

^a Korea Cancer Center Hospital   (South Korea)

Author keywords

Cytokine; Endothelial cells; IL 1 ; Inflammation; Influenza

Indexed keywords

CYCLOOXYGENASE 2; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12P35; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; INTERLEUKIN 8; PROSTAGLANDIN E SYNTHASE; RANTES; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; CYTOKINE; INTERLEUKIN 1 RECEPTOR TYPE I;

ACUTE LUNG INJURY; ANIMAL CELL; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CELL ACTIVATION; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; HOST RESISTANCE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN PULMONARY MICROVASCULAR ENDOTHELIAL CELL; IN VITRO STUDY; INFLUENZA A (H1N1); INFLUENZA VIRUS A H1N1; LUNG ALVEOLUS EPITHELIUM CELL; LUNG FIBROBLAST; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; VIRUS PNEUMONIA; VIRUS REPLICATION; VIRUS STRAIN; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL CULTURE; CELL LINE; ENDOTHELIUM CELL; FIBROBLAST; INFLUENZA; INFLUENZA A VIRUS (H1N1); METABOLISM; PHYSIOLOGY; VIROLOGY;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE;

CELL LINE; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOKINES; ENDOTHELIAL CELLS; FIBROBLASTS; HUMANS; INFLAMMATION MEDIATORS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; INTERLEUKIN-1BETA; PNEUMONIA, VIRAL; RECEPTORS, INTERLEUKIN-1 TYPE I; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

EID: 84928754166     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.24138     Document Type: Article

References (43)

1. Aksentijevich I, Masters SL, Ferguson PJ, Dancey P, Frenkel J, van Royen-Kerkhoff A, Laxer R, Tedgard U, Cowen EW, Pham TH, Booty M, Estes JD, Sandler NG, Plass N, Stone DL, Turner ML, Hill S, Butman JA, Schneider R, Babyn P, El-Shanti HI, Pope E, Barron K, Bing X, Laurence A, Lee CC, Chapelle D, Clarke GI, Ohson K, Nicholson M, Gadina M, Yang B, Korman BD, Gregersen PK, van Hagen PM, Hak AE, Huizing M, Rahman P, Douek DC, Remmers EF, Kastner DL, Goldbach-Mansky R. 2009. An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N Engl J Med 360:2426-2437.
2. Allen IC, Scull MA, Moore CB, Holl EK, McElvania-TeKippe E, Taxman DJ, Guthrie EH, Pickles RJ, Ting JP. 2009. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity 30:556-565.
3. Arend WP, Gabay C. 2000. Physiologic role of interleukin-1 receptor antagonist. Arthritis Res 2:245-248.
4. Arend WP, Malyak M, Guthridge CJ, Gabay C. 1998. Interleukin-1 receptor antagonist: Role in biology. Annu Rev Immunol 16:27-55.
5. Bermejo-Martin JF, Ortiz de Lejarazu, Pumarola R, Rello T, Almansa J, Ramirez R, Martin-Loeches P, Varillas I, Gallegos D, Seron MC, Micheloud C, Gomez D, Tenorio-Abreu JM, Ramos A, Molina MJ, Huidobro ML, Sanchez S, Gordon E, Fernandez M, Del Castillo V, Marcos A, Villanueva MA, Lopez B, Rodriguez-Dominguez CJ, Galan M, Canton JC, Lietor R, Rojo A, Eiros S, Hinojosa JM, Gonzalez C, Torner I, Banner N, Leon D, Cuesta A, Rowe P, Kelvin T. 2009. Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza. Crit Care 13:R201.
6. Besirli CG, Johnson EM, Jr. 2003. JNK-independent activation of c-Jun during neuronal apoptosis induced by multiple DNA-damaging agents. J Biol Chem 278:22357-22366.
7. Bry K, Lappalainen U. 2006. Pathogenesis of bronchopulmonary dysplasia: The role of interleukin 1beta in the regulation of inflammation-mediated pulmonary retinoic acid pathways in transgenic mice. Semin Perinatol 30:121-128.
8. Dinarello CA. 1984. Interleukin-1 and the pathogenesis of the acute-phase response. N Engl J Med 311:1413-1418.
9. Dinarello CA. 2009. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 27:519-550.
10. Dinarello CA. 2011. Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood 117:3720-3732.
11. Dranoff G. 2004. Cytokines in cancer pathogenesis and cancer therapy. Nat Rev Cancer 4:11-22.
12. Fantuzzi G, Dinarello CA. 1996. The inflammatory response in interleukin-1 beta-deficient mice: Comparison with other cytokine-related knock-out mice. J Leukoc Biol 59:489-493.
13. Gabay C. 2002. Cytokine inhibitors in the treatment of rheumatoid arthritis. Expert Opin Biol Ther 2:135-149.
14. Gasse P, Mary C, Guenon I, Noulin N, Charron S, Schnyder-Candrian S, Schnyder B, Akira S, Quesniaux VF, Lagente V, Ryffel B, Couillin I. 2007. IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice. J Clin Invest 117:3786-3799.
15. Glinsky GV. 2010. Genomic analysis of pandemic (H1N1) 2009 reveals association of increasing disease severity with emergence of novel hemagglutinin mutations. Cell Cycle 9:958-970.
16. Hoffman HM, Patel DD. 2004. Genomic-based therapy: Targeting interleukin-1 for autoinflammatory diseases. Arthritis Rheum 50:345-349.
17. Ichinohe T, Lee HK, Ogura Y, Flavell R, Iwasaki A. 2009. Inflammasome recognition of influenza virus is essential for adaptive immune responses. J Exp Med 206:79-87.
18. Julkunen I, Sareneva T, Pirhonen J, Ronni T, Melen K, Matikainen S. 2001. Molecular pathogenesis of influenza A virus infection and virus-induced regulation of cytokine gene expression. Cytokine Growth Factor Rev 12:171-180.
19. Kanneganti TD. 2010. Central roles of NLRs and inflammasomes in viral infection. Nat Rev Immunol 10:688-698.
20. Locksley RM, Killeen N, Lenardo MJ. 2001. The TNF and TNF receptor superfamilies: Integrating mammalian biology. Cell 104:487-501.
21. Marcelin G, Aldridge JR, Duan S, Ghoneim HE, Rehg J, Marjuki H, Boon AC, McCullers JA, Webby RJ. 2011. Fatal outcome of pandemic H1N1 2009 influenza virus infection is associated with immunopathology and impaired lung repair, not enhanced viral burden, in pregnant mice. J Virol 85:11208-11219.
22. Masters SL, Simon A, Aksentijevich I, Kastner DL. 2009. Horror autoinflammaticus: The molecular pathophysiology of autoinflammatory disease (*). Annu Rev Immunol 27:621-668.
23. McCall RD, Haskill S, Zimmermann EM, Lund PK, Thompson RC, Sartor RB. 1994. Tissue interleukin 1 and interleukin-1 receptor antagonist expression in enterocolitis in resistant and susceptible rats. Gastroenterology 106:960-972.
24. McDermott MF, Tschopp J. 2007. From inflammasomes to fevers, crystals and hypertension: How basic research explains inflammatory diseases. Trends Mol Med 13:381-388.
25. McDermott MM, Ferrucci L, Guralnik JM, Tian L, Green D, Liu K, Tan J, Liao Y, Pearce WH, Schneider JR, Ridker P, Rifai N, Hoff F, Criqui MH. 2007. Elevated levels of inflammation, d-dimer, and homocysteine are associated with adverse calf muscle characteristics and reduced calf strength in peripheral arterial disease. J Am Coll Cardiol 50:897-905.
26. Message SD, Johnston SL. 2004. Host defense function of the airway epithelium in health and disease: Clinical background. J Leukoc Biol 75:5-17.
27. Michaelis M, Doerr HW, Cinatl J, Jr. 2009. Of chickens and men: Avian influenza in humans. Curr Mol Med 9:131-151.
28. Netea MG, Simon A, van de Veerdonk F, Kullberg BJ, Van der Meer JW, Joosten LA. 2010. IL-1beta processing in host defense: Beyond the inflammasomes. PLoS Pathog 6: e 1000661.
29. Orfanos SE, Mavrommati I, Korovesi I, Roussos C. 2004. Pulmonary endothelium in acute lung injury: From basic science to the critically ill. Intensive Care Med 30:1702-1714.
30. Schroder K, Tschopp J. 2010. The inflammasomes. Cell 140:821-832.
31. Sedgwick JB, Menon I, Gern JE, Busse WW. 2002. Effects of inflammatory cytokines on the permeability of human lung microvascular endothelial cell monolayers and differential eosinophil transmigration. J Allergy Clin Immunol 110:752-756.
32. Simon A, van der Meer JW. 2007. Pathogenesis of familial periodic fever syndromes or hereditary autoinflammatory syndromes. Am J Physiol Regul Integr Comp Physiol 292:R86-98.
33. Sullivan JL, Mayner RE, Barry DW, Ennis FA. 1976. Influenza virus infection in nude mice. J Infect Dis 133:91-94.
34. Sumikoshi M, Hashimoto K, Kawasaki Y, Sakuma H, Suzutani T, Suzuki H, Hosoya M. 2008. Human influenza virus infection and apoptosis induction in human vascular endothelial cells. J Med Virol 80:1072-1078.
35. Swardfager W, Lanctot K, Rothenburg L, Wong A, Cappell J, Herrmann N. 2010. A meta-analysis of cytokines in Alzheimer's disease. Biol Psychiatry 68:930-941.
36. Teijaro JR, Walsh KB, Cahalan S, Fremgen DM, Roberts E, Scott F, Martinborough E, Peach R, Oldstone MB, Rosen H. 2011. Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection. Cell 146:980-991.
37. Thomas PG, Dash P, Aldridge JR, Jr., Ellebedy AH, Reynolds C, Funk AJ, Martin WJ, Lamkanfi M, Webby RJ, Boyd KL, Doherty PC, Kanneganti TD. 2009. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity 30:566-575.
38. To KK, Hung IF, Li IW, Lee KL, Koo CK, Yan WW, Liu R, Ho KY, Chu KH, Watt CL, Luk WK, Lai KY, Chow FL, Mok T, Buckley T, Chan JF, Wong SS, Zheng B, Chen H, Lau CC, Tse H, Cheng VC, Chan KH, Yuen KY. 2010. Delayed clearance of viral load and marked cytokine activation in severe cases of pandemic H1N1 2009 influenza virus infection. Clin Infect Dis 50:850-859.
39. Van Reeth K. 2000. Cytokines in the pathogenesis of influenza. Vet Microbiol 74:109-116.
40. Vareille M, Kieninger E, Edwards MR, Regamey N. 2011. The airway epithelium: Soldier in the fight against respiratory viruses. Clin Microbiol Rev 24:210-229.
41. Yang N, Hong X, Yang P, Ju X, Wang Y, Tang J, Li C, Fan Q, Zhang F, Chen Z, Xing L, Zhao Z, Gao X, Liao G, Li Q, Wang X, Li D, Jiang C. 2011. The 2009 pandemic A/Wenshan/01/2009 H1N1 induces apoptotic cell death in human airway epithelial cells. J Mol Cell Biol 3:221-229.
42. Zeng H, Pappas C, Belser JA, Houser KV, Zhong W, Wadford DA, Stevens T, Balczon R, Katz JM, Tumpey TM. 2012. Human pulmonary microvascular endothelial cells support productive replication of highly pathogenic avian influenza viruses: Possible involvement in the pathogenesis of human H5N1 virus infection. J Virol 86:667-678.
43. Zheng B, Chan KH, Zhang AJ, Zhou J, Chan CC, Poon VK, Zhang K, Leung VH, Jin DY, Woo PC, Chan JF, To KK, Chen H, Yuen KY. 2010. D225G mutation in hemagglutinin of pandemic influenza H1N1 (2009) virus enhances virulence in mice. Exp Biol Med (Maywood) 235:981-988.