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Volumn 17, Issue 2, 2017, Pages 181-192

The effect of L-dopa in Parkinson’s disease as revealed by neurophysiological studies of motor and sensory functions

Author keywords

kinematic; Levodopa; motor cortex excitability; motor cortex plasticity; Parkinson disease; sequence effect; somatosensory temporal discrimination threshold

Indexed keywords

LEVODOPA; ANTIPARKINSON AGENT; DOPAMINE;

EID: 85007470949     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1080/14737175.2016.1219251     Document Type: Review
Times cited : (30)

References (159)
  • 1
    • 0037333666 scopus 로고    scopus 로고
    • Staging of brain pathology related to sporadic Parkinson’s disease
    • Braak H, Del Tredici K, Rüb U, et al. Staging of brain pathology related to sporadic Parkinson’s disease. Neurobiol Aging. 2003;24(2):197–211.
    • (2003) Neurobiol Aging , vol.24 , Issue.2 , pp. 197-211
    • Braak, H.1    Del Tredici, K.2    Rüb, U.3
  • 2
    • 71849092190 scopus 로고    scopus 로고
    • Neuropathological assessment of Parkinson’s disease: refining the diagnostic criteria
    • Dickson DW, Braak H, Duda JE, et al. Neuropathological assessment of Parkinson’s disease:refining the diagnostic criteria. Lancet Neurol. 2009;8(12):1150–1157.
    • (2009) Lancet Neurol , vol.8 , Issue.12 , pp. 1150-1157
    • Dickson, D.W.1    Braak, H.2    Duda, J.E.3
  • 3
    • 66949152096 scopus 로고    scopus 로고
    • Parkinson’s disease
    • Jun
    • Lees AJ, Hardy J, Revesz T., Parkinson’s disease. Lancet. 2009 Jun 13;373(9680):2055–2066.
    • (2009) Lancet , vol.373 , Issue.9680 , pp. 2055-2066
    • Lees, A.J.1    Hardy, J.2    Revesz, T.3
  • 4
    • 33846077467 scopus 로고    scopus 로고
    • Circuits and circuit disorders of the basal ganglia
    • DeLong MR, Wichmann T. Circuits and circuit disorders of the basal ganglia. Arch Neurol. 2007;64:20–24.
    • (2007) Arch Neurol , vol.64 , pp. 20-24
    • DeLong, M.R.1    Wichmann, T.2
  • 5
    • 0019482818 scopus 로고
    • Dopamine receptors: subtypes, localization and regulation
    • Creese I, Sibley DR, Leff S, et al. Dopamine receptors:subtypes, localization and regulation. Fed Proc. 1981;40(2):147–152.
    • (1981) Fed Proc , vol.40 , Issue.2 , pp. 147-152
    • Creese, I.1    Sibley, D.R.2    Leff, S.3
  • 6
    • 77958465056 scopus 로고    scopus 로고
    • Goal-directed and habitual control in the basal ganglia: implications for Parkinson’s disease
    • Redgrave P, Rodriguez M, Smith Y, et al. Goal-directed and habitual control in the basal ganglia:implications for Parkinson’s disease. Nat Rev Neurosci. 2010;11(11):760–772.
    • (2010) Nat Rev Neurosci , vol.11 , Issue.11 , pp. 760-772
    • Redgrave, P.1    Rodriguez, M.2    Smith, Y.3
  • 7
    • 84930982564 scopus 로고    scopus 로고
    • Levodopa-induced plasticity: a double-edged sword in Parkinson’s disease?
    • Calabresi P, Ghiglieri V, Mazzocchetti P, et al. Levodopa-induced plasticity:a double-edged sword in Parkinson’s disease?. Philos Trans R Soc Lond B Biol Sci. 2015;370(1672). pii:20140184.
    • (2015) Philos Trans R Soc Lond B Biol Sci , vol.370 , Issue.1672
    • Calabresi, P.1    Ghiglieri, V.2    Mazzocchetti, P.3
  • 8
    • 84904961722 scopus 로고    scopus 로고
    • Direct and indirect pathways of basal ganglia: a critical reappraisal
    • Calabresi P, Picconi B, Tozzi A, et al. Direct and indirect pathways of basal ganglia:a critical reappraisal. Nat Neurosci. 2014;17(8):1022–1030.
    • (2014) Nat Neurosci , vol.17 , Issue.8 , pp. 1022-1030
    • Calabresi, P.1    Picconi, B.2    Tozzi, A.3
  • 9
    • 19744378296 scopus 로고    scopus 로고
    • Levodopa and the progression of Parkinson’s disease
    • Fahn S, Oakes D, Shoulson I, et al. Levodopa and the progression of Parkinson’s disease. New Engl J Med. 2004;351(24):2498–2508.
    • (2004) New Engl J Med , vol.351 , Issue.24 , pp. 2498-2508
    • Fahn, S.1    Oakes, D.2    Shoulson, I.3
  • 10
    • 39149122867 scopus 로고    scopus 로고
    • The clinical diagnostic utility of transcranial magnetic stimulation: report of an IFCN committee
    • Chen R, Cros D, Currà A, et al. The clinical diagnostic utility of transcranial magnetic stimulation:report of an IFCN committee. Clin Neurophysiol. 2008;119:504–532.
    • (2008) Clin Neurophysiol , vol.119 , pp. 504-532
    • Chen, R.1    Cros, D.2    Currà, A.3
  • 11
    • 49649127191 scopus 로고    scopus 로고
    • Consensus paper on short-interval intracortical inhibition and other transcranial magnetic stimulation intracortical paradigms in movement disorders
    • Berardelli A, Abbruzzese G, Chen R, et al. Consensus paper on short-interval intracortical inhibition and other transcranial magnetic stimulation intracortical paradigms in movement disorders. Brain Stim. 2008;1:183–191.
    • (2008) Brain Stim , vol.1 , pp. 183-191
    • Berardelli, A.1    Abbruzzese, G.2    Chen, R.3
  • 12
    • 84959441327 scopus 로고    scopus 로고
    • Ten years of theta burst stimulation in humans: established knowledge, unknown and prospects
    • Suppa S, Huang YZ, Funke K, et al. Ten years of theta burst stimulation in humans:established knowledge, unknown and prospects. Brain Stimul. 2016;9:323–335.
    • (2016) Brain Stimul , vol.9 , pp. 323-335
    • Suppa, S.1    Huang, Y.Z.2    Funke, K.3
  • 13
    • 0037168796 scopus 로고    scopus 로고
    • Transcranial magnetic stimulation techniques in clinical investigation
    • Currà A, Modugno N, Inghilleri M, et al. Transcranial magnetic stimulation techniques in clinical investigation. Neurology. 2002 24;59(12):1851–1859.
    • (2002) Neurology , vol.59 , Issue.12 , pp. 1851-1859
    • Currà, A.1    Modugno, N.2    Inghilleri, M.3
  • 14
    • 84890115389 scopus 로고    scopus 로고
    • Pathophysiology of somatosensory abnormalities in Parkinson disease
    • Conte A, Khan N, Defazio G, et al. Pathophysiology of somatosensory abnormalities in Parkinson disease. Nat Rev Neurol. 2013;9:687–697.•• This review summarizes studies investigating sensory abnormalities in Parkinson disease.
    • (2013) Nat Rev Neurol , vol.9 , pp. 687-697
    • Conte, A.1    Khan, N.2    Defazio, G.3
  • 15
    • 0035170381 scopus 로고    scopus 로고
    • Pathophysiology of bradykinesia in Parkinson’s disease
    • Berardelli A, Rothwell JC, Thompson PD, et al. Pathophysiology of bradykinesia in Parkinson’s disease. Brain. 2001;124:2131–2146.•• This review encompasses several experiments investigating the pathophysiology of bradykinesia in Parkinson disease.
    • (2001) Brain , vol.124 , pp. 2131-2146
    • Berardelli, A.1    Rothwell, J.C.2    Thompson, P.D.3
  • 16
    • 0029922211 scopus 로고    scopus 로고
    • Single-joint rapid arm movements in normal subjects and in patients with motor disorders
    • Berardelli A, Hallett M, Rothwell JC, et al. Single-joint rapid arm movements in normal subjects and in patients with motor disorders. Brain. 1996;119(Pt 2):661–674.
    • (1996) Brain , vol.119 , pp. 661-674
    • Berardelli, A.1    Hallett, M.2    Rothwell, J.C.3
  • 17
    • 1542376000 scopus 로고    scopus 로고
    • Effects of deep brain stimulation and medication on bradykinesia and muscle activation in Parkinson’s disease
    • Vaillancourt DE, Prodoehl J, VerhagenMetman L, et al. Effects of deep brain stimulation and medication on bradykinesia and muscle activation in Parkinson’s disease. Brain. 2004;127(Pt 3):491–504.
    • (2004) Brain , vol.127 , pp. 491-504
    • Vaillancourt, D.E.1    Prodoehl, J.2    VerhagenMetman, L.3
  • 19
    • 0034042174 scopus 로고    scopus 로고
    • The control of bimanual reach-to-grasp movements in hemiparkinsonian patients
    • Jackson GM, Jackson SR, Hindle JV. The control of bimanual reach-to-grasp movements in hemiparkinsonian patients. Exp Brain Res. 2000;132:390–398.
    • (2000) Exp Brain Res , vol.132 , pp. 390-398
    • Jackson, G.M.1    Jackson, S.R.2    Hindle, J.V.3
  • 20
    • 0033991277 scopus 로고    scopus 로고
    • The reach-to-grasp movement in Parkinson’s disease before and after dopaminergic medication
    • Castiello U, Bennett KM, Bonfiglioli C, et al. The reach-to-grasp movement in Parkinson’s disease before and after dopaminergic medication. Neuropsychologia. 2000;38(1):46–59.
    • (2000) Neuropsychologia , vol.38 , Issue.1 , pp. 46-59
    • Castiello, U.1    Bennett, K.M.2    Bonfiglioli, C.3
  • 21
    • 50549095400 scopus 로고    scopus 로고
    • Bilateral impairments of skilled reach-to-eat in early Parkinson’s disease patients presenting with unilateral or asymmetrical symptoms
    • Doana JB, Melvinc KG, Whishaw IQ, et al. Bilateral impairments of skilled reach-to-eat in early Parkinson’s disease patients presenting with unilateral or asymmetrical symptoms. Behavioural Brain Research. 2008;194:207–213.
    • (2008) Behavioural Brain Research , vol.194 , pp. 207-213
    • Doana, J.B.1    Melvinc, K.G.2    Whishaw, I.Q.3
  • 22
    • 0141836915 scopus 로고    scopus 로고
    • Effects of pallidotomy and levodopa on walking and reaching movements in Parkinson’s disease
    • Bastian AJ, Kelly VE, Perlmutter JS, et al. Effects of pallidotomy and levodopa on walking and reaching movements in Parkinson’s disease. Mov Disord. 2003;18(9):1008–1017.
    • (2003) Mov Disord , vol.18 , Issue.9 , pp. 1008-1017
    • Bastian, A.J.1    Kelly, V.E.2    Perlmutter, J.S.3
  • 23
    • 0023105583 scopus 로고
    • Disturbance of sequential movements in patients with Parkinson’s disease
    • Benecke R, Rothwell JC, Dick JP, et al. Disturbance of sequential movements in patients with Parkinson’s disease. Brain. 1987;110:361–379.
    • (1987) Brain , vol.110 , pp. 361-379
    • Benecke, R.1    Rothwell, J.C.2    Dick, J.P.3
  • 24
    • 0023829633 scopus 로고
    • The control of bimanual aiming movements in Parkinson’s disease
    • Stelmach GE, Worringham CJ. The control of bimanual aiming movements in Parkinson’s disease. J Neurol Neurosurg Psychiatry. 1988;51(2):223–231.
    • (1988) J Neurol Neurosurg Psychiatry , vol.51 , Issue.2 , pp. 223-231
    • Stelmach, G.E.1    Worringham, C.J.2
  • 25
    • 0030946778 scopus 로고    scopus 로고
    • The bilateral reach-to-grasp movement of Parkinson’s disease subjects
    • Castiello U, Bennett KM. The bilateral reach-to-grasp movement of Parkinson’s disease subjects. Brain. 1997;120(Pt 4):593–604.
    • (1997) Brain , vol.120 , pp. 593-604
    • Castiello, U.1    Bennett, K.M.2
  • 26
    • 0026498470 scopus 로고
    • Sequential arm movements in patients with Parkinson’s disease, Huntington’s disease and dystonia
    • Agostino R, Berardelli A, Formica A, et al. Sequential arm movements in patients with Parkinson’s disease, Huntington’s disease and dystonia. Brain. 1992;115:1481–1495.
    • (1992) Brain , vol.115 , pp. 1481-1495
    • Agostino, R.1    Berardelli, A.2    Formica, A.3
  • 27
    • 0028213985 scopus 로고
    • Analysis of repetitive and nonrepetitive sequential arm movements in patients with Parkinson’s disease
    • Agostino R, Berardelli A, Formica A, et al. Analysis of repetitive and nonrepetitive sequential arm movements in patients with Parkinson’s disease. Mov Disord. 1994;9(3):311–314.
    • (1994) Mov Disord , vol.9 , Issue.3 , pp. 311-314
    • Agostino, R.1    Berardelli, A.2    Formica, A.3
  • 28
    • 78649369420 scopus 로고    scopus 로고
    • Characteristics of the sequence effect in Parkinson’s disease
    • Kang SY, Wasaka T, Shamim EA. Characteristics of the sequence effect in Parkinson’s disease. Mov Disord. 2010;25(13):2148–2155.
    • (2010) Mov Disord , vol.25 , Issue.13 , pp. 2148-2155
    • Kang, S.Y.1    Wasaka, T.2    Shamim, E.A.3
  • 29
    • 84915771046 scopus 로고    scopus 로고
    • Neural correlates of progressive reduction of bradykinesia in de novo Parkinson’s disease
    • Lee E, Lee JE, Yoo K, et al. Neural correlates of progressive reduction of bradykinesia in de novo Parkinson’s disease. Parkinsonism Relat Disord. 2014;20:1376–1381.
    • (2014) Parkinsonism Relat Disord , vol.20 , pp. 1376-1381
    • Lee, E.1    Lee, J.E.2    Yoo, K.3
  • 30
    • 84964608661 scopus 로고    scopus 로고
    • Neural correlates underlying micrographia in Parkinson’s disease
    • Wu T, Zhang J, Hallett M, et al. Neural correlates underlying micrographia in Parkinson’s disease. Brain. 2016;139:144–160.•• The paper clearly shows how the combination of kinematic techniques and neuroimaging provides insight into the pathophysiological mechanisms of motor disturbance in patients with Parkinson’s disease.
    • (2016) Brain , vol.139 , pp. 144-160
    • Wu, T.1    Zhang, J.2    Hallett, M.3
  • 31
    • 22844437952 scopus 로고    scopus 로고
    • Antiparkinson medications improve agonist activation but not antagonist inhibition during sequential reaching movements
    • Kelly VE, Bastian AJ. Antiparkinson medications improve agonist activation but not antagonist inhibition during sequential reaching movements. Mov Disord. 2005;20:694–704.
    • (2005) Mov Disord , vol.20 , pp. 694-704
    • Kelly, V.E.1    Bastian, A.J.2
  • 32
    • 0031947246 scopus 로고    scopus 로고
    • Clinical impairment of sequential finger movements in Parkinson’s disease
    • Agostino R, Berardelli A, Currà A, et al. Clinical impairment of sequential finger movements in Parkinson’s disease. Mov Disord. 1998;13(3):418–421.
    • (1998) Mov Disord , vol.13 , Issue.3 , pp. 418-421
    • Agostino, R.1    Berardelli, A.2    Currà, A.3
  • 33
    • 33847757448 scopus 로고    scopus 로고
    • Movement disorder society-sponsored revision of the unified Parkinson’s disease rating scale (MDS-UPDRS): process, format, and clinimetric testing plan
    • Goetz CG, Fahn S, Martinez-Martin P, et al. Movement disorder society-sponsored revision of the unified Parkinson’s disease rating scale (MDS-UPDRS):process, format, and clinimetric testing plan. Mov Disord. 2007;22:41–47.
    • (2007) Mov Disord , vol.22 , pp. 41-47
    • Goetz, C.G.1    Fahn, S.2    Martinez-Martin, P.3
  • 34
    • 61449165975 scopus 로고    scopus 로고
    • Movement disorder society-sponsored revision of the unified Parkinson’s disease rating scale (MDS-UPDRS): scale presentation and clinimetric testing results
    • Goetz CG, Tilley BC, Shaftman SR, et al. Movement disorder society-sponsored revision of the unified Parkinson’s disease rating scale (MDS-UPDRS):scale presentation and clinimetric testing results. Mov Disord. 2008;23:2129–2170.
    • (2008) Mov Disord , vol.23 , pp. 2129-2170
    • Goetz, C.G.1    Tilley, B.C.2    Shaftman, S.R.3
  • 35
    • 0037809607 scopus 로고    scopus 로고
    • Impairment of individual finger movements in Parkinson’s disease
    • Agostino R, Currà A, Giovannelli M, et al. Impairment of individual finger movements in Parkinson’s disease. Mov Disord. 2003;18(5):560–565.
    • (2003) Mov Disord , vol.18 , Issue.5 , pp. 560-565
    • Agostino, R.1    Currà, A.2    Giovannelli, M.3
  • 36
    • 67651162185 scopus 로고    scopus 로고
    • Impairments of speed and amplitude of movement in Parkinson’s disease: a pilot study
    • Espay AJ, Beaton DE, Morgante F, et al. Impairments of speed and amplitude of movement in Parkinson’s disease:a pilot study. Mov Disord. 2009;24(7):1001–1008.
    • (2009) Mov Disord , vol.24 , Issue.7 , pp. 1001-1008
    • Espay, A.J.1    Beaton, D.E.2    Morgante, F.3
  • 37
    • 81555206409 scopus 로고    scopus 로고
    • Differential response of speed, amplitude, and rhythm to dopaminergic medications in Parkinson’s disease
    • Espay AJ, Giuffrida JP, Chen R, et al. Differential response of speed, amplitude, and rhythm to dopaminergic medications in Parkinson’s disease. Mov Disord. 2011;26(14):2504–2508.•• The paper clearly shows how kinematic techniques provide objective assessment of specific movement disturbance in patients with Parkinson’s disease possibly useful in quantifying both the severity of the disease and the effect of medication.
    • (2011) Mov Disord , vol.26 , Issue.14 , pp. 2504-2508
    • Espay, A.J.1    Giuffrida, J.P.2    Chen, R.3
  • 38
    • 84878785950 scopus 로고    scopus 로고
    • Comparing kinematic changes between a finger-tapping task and unconstrained finger flexion-extension task in patients with Parkinson’s disease
    • Teo WP, Rodrigues JP, Mastaglia FL, et al. Comparing kinematic changes between a finger-tapping task and unconstrained finger flexion-extension task in patients with Parkinson’s disease. Exp Brain Res. 2013;227(3):323–331.
    • (2013) Exp Brain Res , vol.227 , Issue.3 , pp. 323-331
    • Teo, W.P.1    Rodrigues, J.P.2    Mastaglia, F.L.3
  • 40
    • 0020618592 scopus 로고
    • Spontaneous eye-blink rates and dopaminergic systems
    • Karson CN. Spontaneous eye-blink rates and dopaminergic systems. Brain. 1983;106:643–653.
    • (1983) Brain , vol.106 , pp. 643-653
    • Karson, C.N.1
  • 41
    • 0031923369 scopus 로고    scopus 로고
    • Spontaneous and reflex activity of facial muscles in dystonia, Parkinson’s disease, and in normal subjects
    • Deuschl G, Goddemeier C. Spontaneous and reflex activity of facial muscles in dystonia, Parkinson’s disease, and in normal subjects. J NeurolNeurosurgPsychiatry. 1998;64:320–324.
    • (1998) J NeurolNeurosurgPsychiatry , vol.64 , pp. 320-324
    • Deuschl, G.1    Goddemeier, C.2
  • 42
    • 33846103346 scopus 로고    scopus 로고
    • The ratio of square wave jerk rates to blink rates distinguishes progressive supranuclear palsy from Parkinson disease
    • Altiparmak UE, Eggenberger E, Coleman A, et al. The ratio of square wave jerk rates to blink rates distinguishes progressive supranuclear palsy from Parkinson disease. J Neuroophthalmol. 2006;26:257–259.
    • (2006) J Neuroophthalmol , vol.26 , pp. 257-259
    • Altiparmak, U.E.1    Eggenberger, E.2    Coleman, A.3
  • 43
    • 33748370119 scopus 로고    scopus 로고
    • Eyelid movements during blinking in patients with Parkinson’s disease
    • Korosec M, Zidar I, Reits D, et al. Eyelid movements during blinking in patients with Parkinson’s disease. Mov Disord. 2006;21:1248–1251.
    • (2006) Mov Disord , vol.21 , pp. 1248-1251
    • Korosec, M.1    Zidar, I.2    Reits, D.3
  • 44
    • 0033814187 scopus 로고    scopus 로고
    • Increased blink rate in advanced Parkinson’s disease: a form of ‘off’-period dystonia?
    • Kimber TE, Thompson PD. Increased blink rate in advanced Parkinson’s disease:a form of ‘off’-period dystonia? Mov Disord. 2000;15(5):982–985.
    • (2000) Mov Disord , vol.15 , Issue.5 , pp. 982-985
    • Kimber, T.E.1    Thompson, P.D.2
  • 45
    • 44449169066 scopus 로고    scopus 로고
    • Voluntary, spontaneous, and reflex blinking in Parkinson’s disease
    • Agostino R, Bologna M, Dinapoli L, et al. Voluntary, spontaneous, and reflex blinking in Parkinson’s disease. Mov Disord. 2008;15:669–675.
    • (2008) Mov Disord , vol.15 , pp. 669-675
    • Agostino, R.1    Bologna, M.2    Dinapoli, L.3
  • 46
    • 84859914540 scopus 로고    scopus 로고
    • Effects of subthalamic nucleus deep brain stimulation and L-DOPA on blinking in Parkinson’s disease
    • Bologna M, Fasano A, Modugno N, et al. Effects of subthalamic nucleus deep brain stimulation and L-DOPA on blinking in Parkinson’s disease. Exp Neurol. 2012;235(1):265–272.
    • (2012) Exp Neurol , vol.235 , Issue.1 , pp. 265-272
    • Bologna, M.1    Fasano, A.2    Modugno, N.3
  • 47
    • 84897963080 scopus 로고    scopus 로고
    • Bradykinesia of posed smiling and voluntary movement of the lower face in Parkinson’s disease
    • Marsili L, Agostino R, Bologna M, et al. Bradykinesia of posed smiling and voluntary movement of the lower face in Parkinson’s disease. Parkinsonism Relat Disord. 2014;20(4):370–375.
    • (2014) Parkinsonism Relat Disord , vol.20 , Issue.4 , pp. 370-375
    • Marsili, L.1    Agostino, R.2    Bologna, M.3
  • 48
    • 0023194476 scopus 로고
    • Labial kinematics during speech in patients with parkinsonian rigidity
    • Caligiuri MP. Labial kinematics during speech in patients with parkinsonian rigidity. Brain. 1987;110:1033–1044.
    • (1987) Brain , vol.110 , pp. 1033-1044
    • Caligiuri, M.P.1
  • 49
    • 0024411593 scopus 로고
    • Parkinsonian deficits in serial multiarticulate movements for speech
    • Connor NP, Abbs JH, Cole KJ, et al. Parkinsonian deficits in serial multiarticulate movements for speech. Brain. 1989;112:997–1009.
    • (1989) Brain , vol.112 , pp. 997-1009
    • Connor, N.P.1    Abbs, J.H.2    Cole, K.J.3
  • 50
    • 0034006214 scopus 로고    scopus 로고
    • The clinical use of brainstem reflexes and hand-muscle reflexes
    • Cruccu G, Deuschl G. The clinical use of brainstem reflexes and hand-muscle reflexes. Clin Neurophysiol. 2000;111:371–387.
    • (2000) Clin Neurophysiol , vol.111 , pp. 371-387
    • Cruccu, G.1    Deuschl, G.2
  • 51
    • 84655165051 scopus 로고    scopus 로고
    • Assessment of excitability in brainstem circuits mediating the blink reflex and the startle reaction
    • Jan
    • Valls-Sole J. Assessment of excitability in brainstem circuits mediating the blink reflex and the startle reaction. Clin Neurophysiol. 2012 Jan;123(1):13–20.
    • (2012) Clin Neurophysiol , vol.123 , Issue.1 , pp. 13-20
    • Valls-Sole, J.1
  • 52
    • 0014801827 scopus 로고
    • Electrodiagnostic study of trigeminal nerve. Orbicularis oculi reflex and masseter reflex in trigeminal neuralgia, paratrigeminal syndrome, and other lesions of the trigeminal nerve
    • Kimura J, Rodnitzky RL, Van Allen MW. Electrodiagnostic study of trigeminal nerve. Orbicularis oculi reflex and masseter reflex in trigeminal neuralgia, paratrigeminal syndrome, and other lesions of the trigeminal nerve. Neurology. 1970;20(6):574–583.
    • (1970) Neurology , vol.20 , Issue.6 , pp. 574-583
    • Kimura, J.1    Rodnitzky, R.L.2    Van Allen, M.W.3
  • 54
    • 0036307937 scopus 로고    scopus 로고
    • Brainstem reflexes: electrodiagnostic techniques, physiology, normative data, and clinical applications
    • Jul
    • Aramideh M, Ongerboer de Visser BW. Brainstem reflexes:electrodiagnostic techniques, physiology, normative data, and clinical applications. Muscle Nerve. 2002 Jul;26(1):14–30.
    • (2002) Muscle Nerve , vol.26 , Issue.1 , pp. 14-30
    • Aramideh, M.1    Ongerboer de Visser, B.W.2
  • 55
    • 13544265326 scopus 로고    scopus 로고
    • Brainstem reflex circuits revisited
    • Cruccu G, Iannetti GD, Marx JJ, et al. Brainstem reflex circuits revisited. Brain. 2005;128(Pt 2):386–394.
    • (2005) Brain , vol.128 , pp. 386-394
    • Cruccu, G.1    Iannetti, G.D.2    Marx, J.J.3
  • 56
    • 0029803456 scopus 로고    scopus 로고
    • An explanation for reflex blink hyperexcitability in Parkinson’s disease. II. Nucleus raphe magnus
    • Basso MA, Evinger C. An explanation for reflex blink hyperexcitability in Parkinson’s disease. II. Nucleus raphe magnus. J Neurosci. 1996;16(22):7318–7330.
    • (1996) J Neurosci , vol.16 , Issue.22 , pp. 7318-7330
    • Basso, M.A.1    Evinger, C.2
  • 57
    • 0029850519 scopus 로고    scopus 로고
    • An explanation for reflex blink hyperexcitability in Parkinson’s disease. I. Superior colliculus
    • Basso MA, Powers AS, Evinger C. An explanation for reflex blink hyperexcitability in Parkinson’s disease. I. Superior colliculus. J Neurosci. 1996;16(22):7308–7317.
    • (1996) J Neurosci , vol.16 , Issue.22 , pp. 7308-7317
    • Basso, M.A.1    Powers, A.S.2    Evinger, C.3
  • 58
    • 44449169066 scopus 로고    scopus 로고
    • Voluntary, spontaneous, and reflex blinking in Parkinson’s disease
    • Apr
    • Agostino R, Bologna M, Dinapoli L, et al. Voluntary, spontaneous, and reflex blinking in Parkinson’s disease. Mov Disord. 2008 Apr 15;23(5):669–675.
    • (2008) Mov Disord , vol.23 , Issue.5 , pp. 669-675
    • Agostino, R.1    Bologna, M.2    Dinapoli, L.3
  • 59
    • 0036724027 scopus 로고    scopus 로고
    • Effects of deep brain stimulation and levodopa on postural sway in Parkinson’s disease
    • Rocchi L, Chiari L, Horak FB. Effects of deep brain stimulation and levodopa on postural sway in Parkinson’s disease. J Neurol Neurosurg Psychiatry. 2002;73(3):267–274.
    • (2002) J Neurol Neurosurg Psychiatry , vol.73 , Issue.3 , pp. 267-274
    • Rocchi, L.1    Chiari, L.2    Horak, F.B.3
  • 60
    • 84933519636 scopus 로고    scopus 로고
    • The effect of levodopa on postural stability evaluated by wearable inertial measurement units for idiopathic and vascular Parkinson’s disease
    • Gago MF, Fernandes V, Ferreira J, et al. The effect of levodopa on postural stability evaluated by wearable inertial measurement units for idiopathic and vascular Parkinson’s disease. Gait Posture. 2015;41(2):459–464.
    • (2015) Gait Posture , vol.41 , Issue.2 , pp. 459-464
    • Gago, M.F.1    Fernandes, V.2    Ferreira, J.3
  • 61
    • 84942296438 scopus 로고    scopus 로고
    • Beneficial effect of levodopa therapy on stooped posture in Parkinson’s disease
    • Benninger F, Khlebtovsky A, Roditi Y, et al. Beneficial effect of levodopa therapy on stooped posture in Parkinson’s disease. Gait Posture. 2015;42(3):263–268.
    • (2015) Gait Posture , vol.42 , Issue.3 , pp. 263-268
    • Benninger, F.1    Khlebtovsky, A.2    Roditi, Y.3
  • 62
    • 14044249545 scopus 로고    scopus 로고
    • Three-dimensional gait biomechanics in Parkinson’s disease: evidence for a centrally mediated amplitude regulation disorder
    • Morris M, Iansek R, McGinley J, et al. Three-dimensional gait biomechanics in Parkinson’s disease:evidence for a centrally mediated amplitude regulation disorder. Mov Disord. 2005;20(1):40–50.
    • (2005) Mov Disord , vol.20 , Issue.1 , pp. 40-50
    • Morris, M.1    Iansek, R.2    McGinley, J.3
  • 63
    • 33750292573 scopus 로고    scopus 로고
    • The sequence effect and gait festination in Parkinson disease: contributors to freezing of gait?
    • Iansek R, Huxham F, McGinley J. The sequence effect and gait festination in Parkinson disease:contributors to freezing of gait? Mov Disord. 2006;21(9):1419–1424.
    • (2006) Mov Disord , vol.21 , Issue.9 , pp. 1419-1424
    • Iansek, R.1    Huxham, F.2    McGinley, J.3
  • 64
    • 84933510404 scopus 로고    scopus 로고
    • Gait in drug naïve patients with de novo Parkinson’s disease–altered but symmetric
    • Grajić M, Stanković I, Radovanović S, et al. Gait in drug naïve patients with de novo Parkinson’s disease–altered but symmetric. Neurol Res. 2015;37(8):712–716.
    • (2015) Neurol Res , vol.37 , Issue.8 , pp. 712-716
    • Grajić, M.1    Stanković, I.2    Radovanović, S.3
  • 65
    • 79960348433 scopus 로고    scopus 로고
    • Freezing of gait: moving forward on a mysterious clinical phenomenon
    • Nutt JG, Bloem BR, Giladi N, et al. Freezing of gait:moving forward on a mysterious clinical phenomenon. Lancet Neurol. 2011;10:734–744.
    • (2011) Lancet Neurol , vol.10 , pp. 734-744
    • Nutt, J.G.1    Bloem, B.R.2    Giladi, N.3
  • 66
    • 0026523808 scopus 로고
    • Motor blocks in Parkinson’s disease
    • Giladi N, McMahon D, Przedborski S, et al. Motor blocks in Parkinson’s disease. Neurology. 1992;42(2):333–339.
    • (1992) Neurology , vol.42 , Issue.2 , pp. 333-339
    • Giladi, N.1    McMahon, D.2    Przedborski, S.3
  • 67
    • 77954753603 scopus 로고    scopus 로고
    • Predictors of future falls in Parkinson disease
    • Kerr GK, Worringham CJ, Cole MH, et al. Predictors of future falls in Parkinson disease. Neurology. 2010;75:116–124.
    • (2010) Neurology , vol.75 , pp. 116-124
    • Kerr, G.K.1    Worringham, C.J.2    Cole, M.H.3
  • 68
    • 1542328198 scopus 로고    scopus 로고
    • Effects of subthalamic nucleus stimulation and L-dopa in trunk kinematics of patients with Parkinson’s disease
    • Ferrarin M, Rizzone M, Lopiano L, et al. Effects of subthalamic nucleus stimulation and L-dopa in trunk kinematics of patients with Parkinson’s disease. Gait Posture. 2004;19(2):164–171.
    • (2004) Gait Posture , vol.19 , Issue.2 , pp. 164-171
    • Ferrarin, M.1    Rizzone, M.2    Lopiano, L.3
  • 69
    • 0029981855 scopus 로고    scopus 로고
    • Stride length regulation in Parkinson’s disease. Normalization strategies and underlying mechanism
    • Morris ME, Iansek R, Matyas TA, et al. Stride length regulation in Parkinson’s disease. Normalization strategies and underlying mechanism. Brain. 1996;119:551–568.
    • (1996) Brain , vol.119 , pp. 551-568
    • Morris, M.E.1    Iansek, R.2    Matyas, T.A.3
  • 70
    • 0028859785 scopus 로고
    • Changes in excitability of motor cortical circuitry in patients with Parkinson’s disease
    • Ridding MC, Inzelberg R, Rothwell JC. Changes in excitability of motor cortical circuitry in patients with Parkinson’s disease. Ann Neurol. 1995;37(2):181–188.
    • (1995) Ann Neurol , vol.37 , Issue.2 , pp. 181-188
    • Ridding, M.C.1    Inzelberg, R.2    Rothwell, J.C.3
  • 71
    • 0034237299 scopus 로고    scopus 로고
    • Effects of chronic levodopa and pergolide treatment on cortical excitability in patients with Parkinson’s disease: a transcranial magnetic stimulation study
    • Strafella AP, Valzania F, Nassetti SA, et al. Effects of chronic levodopa and pergolide treatment on cortical excitability in patients with Parkinson’s disease:a transcranial magnetic stimulation study. Clin Neurophysiol. 2000;111(7):1198–1202.
    • (2000) Clin Neurophysiol , vol.111 , Issue.7 , pp. 1198-1202
    • Strafella, A.P.1    Valzania, F.2    Nassetti, S.A.3
  • 72
    • 0043288020 scopus 로고    scopus 로고
    • Intracortical inhibition and facilitation are impaired in patients with early Parkinson’s disease: a paired TMS study
    • Bares M, Kanovský P, Klajblová H, et al. Intracortical inhibition and facilitation are impaired in patients with early Parkinson’s disease:a paired TMS study. Eur J Neurol. 2003;10(4):385–389.
    • (2003) Eur J Neurol , vol.10 , Issue.4 , pp. 385-389
    • Bares, M.1    Kanovský, P.2    Klajblová, H.3
  • 73
    • 25444504793 scopus 로고    scopus 로고
    • Pathways mediating abnormal intracortical inhibition in Parkinson’s disease
    • MacKinnon CD, Gilley EA, Weis-McNulty A, et al. Pathways mediating abnormal intracortical inhibition in Parkinson’s disease. Ann Neurol. 2005;58:516–524.
    • (2005) Ann Neurol , vol.58 , pp. 516-524
    • MacKinnon, C.D.1    Gilley, E.A.2    Weis-McNulty, A.3
  • 74
    • 84879113338 scopus 로고    scopus 로고
    • Increased motor cortical facilitation and decreased inhibition in Parkinson disease
    • Ni Z, Bahl N, Gunraj CA, et al. Increased motor cortical facilitation and decreased inhibition in Parkinson disease. Neurology. 2013;80:1746–1753.
    • (2013) Neurology , vol.80 , pp. 1746-1753
    • Ni, Z.1    Bahl, N.2    Gunraj, C.A.3
  • 75
    • 0029960871 scopus 로고    scopus 로고
    • Cortical inhibition in Parkinson’s disease. A study with paired magnetic stimulation
    • Berardelli A, Rona S, Inghilleri M, et al. Cortical inhibition in Parkinson’s disease. A study with paired magnetic stimulation. Brain. 1996;119(Pt 1):71–77.
    • (1996) Brain , vol.119 , pp. 71-77
    • Berardelli, A.1    Rona, S.2    Inghilleri, M.3
  • 76
    • 0035208735 scopus 로고    scopus 로고
    • Transcranial magnetic stimulation can be used to test connections to primary motor areas from frontal and medial cortex in humans
    • Civardi C, Cantello R, Asselman P, et al. Transcranial magnetic stimulation can be used to test connections to primary motor areas from frontal and medial cortex in humans. Neuroimage. 2001;14:1444–1453.
    • (2001) Neuroimage , vol.14 , pp. 1444-1453
    • Civardi, C.1    Cantello, R.2    Asselman, P.3
  • 77
    • 34250866762 scopus 로고    scopus 로고
    • Focal stimulation of the posterior parietal cortex increases the excitability of the ipsilateral motor cortex
    • Koch G, Fernandez Del Olmo M, Cheeran B, et al. Focal stimulation of the posterior parietal cortex increases the excitability of the ipsilateral motor cortex. J Neurosci. 2007;27:6815–6822.
    • (2007) J Neurosci , vol.27 , pp. 6815-6822
    • Koch, G.1    Fernandez Del Olmo, M.2    Cheeran, B.3
  • 78
    • 33846242102 scopus 로고    scopus 로고
    • Interactions between pairs of transcranial magnetic stimuli over the human left dorsal premotor cortex differ from those seen in primary motor cortex
    • Koch G, Franca M, Mochizuki H, et al. Interactions between pairs of transcranial magnetic stimuli over the human left dorsal premotor cortex differ from those seen in primary motor cortex. J Physiol. 2007;578:551–562.
    • (2007) J Physiol , vol.578 , pp. 551-562
    • Koch, G.1    Franca, M.2    Mochizuki, H.3
  • 79
    • 10344257567 scopus 로고    scopus 로고
    • Abnormal excitability of premotor-motor connections in de novo Parkinson’s disease
    • Buhmann C, Gorsler A, Bäumer T, et al. Abnormal excitability of premotor-motor connections in de novo Parkinson’s disease. Brain. 2004;127:2732–2746.
    • (2004) Brain , vol.127 , pp. 2732-2746
    • Buhmann, C.1    Gorsler, A.2    Bäumer, T.3
  • 80
    • 20444422135 scopus 로고    scopus 로고
    • Dopaminergic drugs restore facilitatory premotor–motor interactions in Parkinson’s disease
    • Mir P, Matsunaga K, Gilio F, et al. Dopaminergic drugs restore facilitatory premotor–motor interactions in Parkinson’s disease. Neurology. 2005;64:1906–1912.
    • (2005) Neurology , vol.64 , pp. 1906-1912
    • Mir, P.1    Matsunaga, K.2    Gilio, F.3
  • 81
    • 84922080408 scopus 로고    scopus 로고
    • Effects of dopaminergic treatment on functional cortico-cortical connectivity in Parkinson’s disease
    • Zittel S, Heinbokel C, van der Vegt JP, et al. Effects of dopaminergic treatment on functional cortico-cortical connectivity in Parkinson’s disease. Exp Brain Res. 2015;233:329–337.
    • (2015) Exp Brain Res , vol.233 , pp. 329-337
    • Zittel, S.1    Heinbokel, C.2    van der Vegt, J.P.3
  • 82
    • 84879894153 scopus 로고    scopus 로고
    • Study of cerebello-thalamocortical pathway by transcranial magnetic stimulation in Parkinson’s disease
    • Carrillo F, Palomar FJ, Conde V, et al. Study of cerebello-thalamocortical pathway by transcranial magnetic stimulation in Parkinson’s disease. Brain Stimul. 2013;6:582–589.
    • (2013) Brain Stimul , vol.6 , pp. 582-589
    • Carrillo, F.1    Palomar, F.J.2    Conde, V.3
  • 83
    • 0027989493 scopus 로고
    • Responses to rapid-rate transcranial magnetic stimulation of the human motor cortex
    • Pascual-Leone A, Valls-Solé J, Wassermann EM, et al. Responses to rapid-rate transcranial magnetic stimulation of the human motor cortex. Brain. 1994;117:847–858.
    • (1994) Brain , vol.117 , pp. 847-858
    • Pascual-Leone, A.1    Valls-Solé, J.2    Wassermann, E.M.3
  • 85
    • 39149110893 scopus 로고    scopus 로고
    • Preconditioning rTMS of premotor cortex can reduce but not enhance short-term facilitation of primary motor cortex
    • Suppa A, Bologna M, Gilio F, et al. Preconditioning rTMS of premotor cortex can reduce but not enhance short-term facilitation of primary motor cortex. J Neurophysiol. 2008;99:564–570.
    • (2008) J Neurophysiol , vol.99 , pp. 564-570
    • Suppa, A.1    Bologna, M.2    Gilio, F.3
  • 86
    • 0036589838 scopus 로고    scopus 로고
    • Repetitive magnetic stimulation of cortical motor areas in Parkinson’s disease: implications for the pathophysiology of cortical function
    • Gilio F, Curra A, Inghilleri M, et al. Repetitive magnetic stimulation of cortical motor areas in Parkinson’s disease:implications for the pathophysiology of cortical function. Mov Disord. 2002;17:467–473.
    • (2002) Mov Disord , vol.17 , pp. 467-473
    • Gilio, F.1    Curra, A.2    Inghilleri, M.3
  • 87
    • 77955977417 scopus 로고    scopus 로고
    • Dopamine influences primary motor cortex plasticity and dorsal premotor-to-motor connectivity in Parkinson’s disease
    • Suppa A, Iezzi E, Conte A, et al. Dopamine influences primary motor cortex plasticity and dorsal premotor-to-motor connectivity in Parkinson’s disease. Cereb Cortex. 2010;20:2224–2233.
    • (2010) Cereb Cortex , vol.20 , pp. 2224-2233
    • Suppa, A.1    Iezzi, E.2    Conte, A.3
  • 88
    • 29944433214 scopus 로고    scopus 로고
    • Altered plasticity of the human motor cortex in Parkinson’s disease
    • Ueki Y, Mima T, Ali Kotb M, et al. Altered plasticity of the human motor cortex in Parkinson’s disease. Ann Neurol. 2006;59:60–71.
    • (2006) Ann Neurol , vol.59 , pp. 60-71
    • Ueki, Y.1    Mima, T.2    Ali Kotb, M.3
  • 89
    • 33645062930 scopus 로고    scopus 로고
    • Motor cortex plasticity in Parkinson’s disease and levodopa-induced dyskinesias
    • Morgante F, Espay AJ, Gunraj C, et al. Motor cortex plasticity in Parkinson’s disease and levodopa-induced dyskinesias. Brain. 2006;129:1059–1069.• This paper is important to understand the role played by changes in motor cortex plasticity in the development of motor symptoms and dyskinesias in Parkison’s disease.
    • (2006) Brain , vol.129 , pp. 1059-1069
    • Morgante, F.1    Espay, A.J.2    Gunraj, C.3
  • 90
    • 84877040092 scopus 로고    scopus 로고
    • Differences in dopaminergic modulation to motor cortical plasticity between Parkinson’s disease and multiple system atrophy
    • Kawashima S, Ueki Y, Mima T, et al. Differences in dopaminergic modulation to motor cortical plasticity between Parkinson’s disease and multiple system atrophy. PLoS ONE. 2013;8:e62515.
    • (2013) PLoS ONE , vol.8 , pp. 62515
    • Kawashima, S.1    Ueki, Y.2    Mima, T.3
  • 91
    • 33646920860 scopus 로고    scopus 로고
    • Plasticity of the motor cortex in Parkinson’s disease patients on and off therapy
    • Bagnato S, Agostino R, Modugno N, et al. Plasticity of the motor cortex in Parkinson’s disease patients on and off therapy. Mov Disord. 2006;21:639–645.
    • (2006) Mov Disord , vol.21 , pp. 639-645
    • Bagnato, S.1    Agostino, R.2    Modugno, N.3
  • 92
    • 84860720112 scopus 로고    scopus 로고
    • Functional reorganization of sensorimotor cortex in early Parkinson disease
    • Kojovic M, Bologna M, Kassavetis P, et al. Functional reorganization of sensorimotor cortex in early Parkinson disease. Neurology. 2012;78:1441–1448.
    • (2012) Neurology , vol.78 , pp. 1441-1448
    • Kojovic, M.1    Bologna, M.2    Kassavetis, P.3
  • 93
    • 84924038947 scopus 로고    scopus 로고
    • Transcranial magnetic stimulation follow-up study in early Parkinson’s disease: a decline in compensation with disease progression?
    • Kojovic M, Kassavetis P, Bologna M, et al. Transcranial magnetic stimulation follow-up study in early Parkinson’s disease:a decline in compensation with disease progression? Mov Disord. 2015;30:1098–1106.
    • (2015) Mov Disord , vol.30 , pp. 1098-1106
    • Kojovic, M.1    Kassavetis, P.2    Bologna, M.3
  • 94
    • 12344287391 scopus 로고    scopus 로고
    • Theta burst stimulation of the human motor cortex
    • Huang YZ, Edwards MJ, Rounis E, et al. Theta burst stimulation of the human motor cortex. Neuron. 2005;45:201–206.
    • (2005) Neuron , vol.45 , pp. 201-206
    • Huang, Y.Z.1    Edwards, M.J.2    Rounis, E.3
  • 95
    • 78650958515 scopus 로고    scopus 로고
    • Theta burst stimulation over the primary motor cortex does not induce cortical plasticity in Parkinson’s disease
    • Eggers C, Fink GR, Nowak DA. Theta burst stimulation over the primary motor cortex does not induce cortical plasticity in Parkinson’s disease. J Neurol. 2010;257:1669–1674.
    • (2010) J Neurol , vol.257 , pp. 1669-1674
    • Eggers, C.1    Fink, G.R.2    Nowak, D.A.3
  • 96
    • 78651434926 scopus 로고    scopus 로고
    • Lack of LTP-like plasticity in primary motor cortex in Parkinson’s disease
    • Suppa A, Marsili L, Belvisi D, et al. Lack of LTP-like plasticity in primary motor cortex in Parkinson’s disease. Exp Neurol. 2011;227:296–301.
    • (2011) Exp Neurol , vol.227 , pp. 296-301
    • Suppa, A.1    Marsili, L.2    Belvisi, D.3
  • 97
    • 84857790746 scopus 로고    scopus 로고
    • Early, severe and bilateral loss of LTP and LTD-like plasticity in motor cortex (M1) in de novo Parkinson’s disease
    • Kishore A, Joseph T, Velayudhan B, et al. Early, severe and bilateral loss of LTP and LTD-like plasticity in motor cortex (M1) in de novo Parkinson’s disease. Clin Neurophysiol. 2012;123:822–828.
    • (2012) Clin Neurophysiol , vol.123 , pp. 822-828
    • Kishore, A.1    Joseph, T.2    Velayudhan, B.3
  • 98
    • 84857790015 scopus 로고    scopus 로고
    • Effects of theta burst stimulation on motor cortex excitability in Parkinson’s disease
    • Zamir O, Gunraj C, Ni Z, et al. Effects of theta burst stimulation on motor cortex excitability in Parkinson’s disease. Clin Neurophysiol. 2012;123:815–821.
    • (2012) Clin Neurophysiol , vol.123 , pp. 815-821
    • Zamir, O.1    Gunraj, C.2    Ni, Z.3
  • 99
    • 80052009184 scopus 로고    scopus 로고
    • Abnormal bidirectional plasticity-like effects in Parkinson’s disease
    • Huang YZ, Rothwell JC, Lu CS, et al. Abnormal bidirectional plasticity-like effects in Parkinson’s disease. Brain. 2011;134:2312–2320.
    • (2011) Brain , vol.134 , pp. 2312-2320
    • Huang, Y.Z.1    Rothwell, J.C.2    Lu, C.S.3
  • 100
    • 39549087461 scopus 로고    scopus 로고
    • Paradoxes of functional neurosurgery: clues from basal ganglia recordings
    • Brown P, Eusebio A. Paradoxes of functional neurosurgery:clues from basal ganglia recordings. Mov Disord. 2008;23(1):12–20.
    • (2008) Mov Disord , vol.23 , Issue.1 , pp. 12-20
    • Brown, P.1    Eusebio, A.2
  • 101
    • 84887952852 scopus 로고    scopus 로고
    • The functional role of beta oscillations in Parkinson’s disease
    • Little S, Brown P. The functional role of beta oscillations in Parkinson’s disease. Parkinsonism Relat Disord. 2014;20(Suppl 1):S44–S48.
    • (2014) Parkinsonism Relat Disord , vol.20 , pp. S44-S48
    • Little, S.1    Brown, P.2
  • 102
    • 84880150978 scopus 로고    scopus 로고
    • What basal ganglia changes underlie the parkinsonian state? The significance of neuronal oscillatory activity
    • Quiroga-Varela A, Walters JR, Brazhnik E, et al. What basal ganglia changes underlie the parkinsonian state? The significance of neuronal oscillatory activity. Neurobiol Dis. 2013;58:242–248.
    • (2013) Neurobiol Dis , vol.58 , pp. 242-248
    • Quiroga-Varela, A.1    Walters, J.R.2    Brazhnik, E.3
  • 103
    • 0028021805 scopus 로고
    • The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism
    • Bergman H, Wichmann T, Karmon B, et al. The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism. J Neurophysiol. 1994;72:507–520.
    • (1994) J Neurophysiol , vol.72 , pp. 507-520
    • Bergman, H.1    Wichmann, T.2    Karmon, B.3
  • 104
    • 0028843806 scopus 로고
    • Neurons in the globus pallidus do not show correlated activity in the normal monkey, but phase-locked oscillations appearin the MPTP model of parkinsonism
    • Nini A, Feingold A, Slovin H, et al. Neurons in the globus pallidus do not show correlated activity in the normal monkey, but phase-locked oscillations appearin the MPTP model of parkinsonism. J Neurophysiol. 1995;74:1800–1805.
    • (1995) J Neurophysiol , vol.74 , pp. 1800-1805
    • Nini, A.1    Feingold, A.2    Slovin, H.3
  • 105
    • 0035115941 scopus 로고    scopus 로고
    • Dopaminedependency of oscillations between subthalamic nucleus and pallidum inParkinson’s disease
    • Brown P, Oliviero A, Mazzone P, et al. Dopaminedependency of oscillations between subthalamic nucleus and pallidum inParkinson’s disease. J Neurosci. 2001;21:1033–1038.
    • (2001) J Neurosci , vol.21 , pp. 1033-1038
    • Brown, P.1    Oliviero, A.2    Mazzone, P.3
  • 106
    • 4544264161 scopus 로고    scopus 로고
    • Rhythm-specific pharmacological modulation of subthalamic activity in Parkinson’s disease
    • Priori A, Foffani G, Pesenti A, et al. Rhythm-specific pharmacological modulation of subthalamic activity in Parkinson’s disease. Exp Neurol. 2004;189:369–379.
    • (2004) Exp Neurol , vol.189 , pp. 369-379
    • Priori, A.1    Foffani, G.2    Pesenti, A.3
  • 107
    • 33751508139 scopus 로고    scopus 로고
    • Beta oscillatory activity in the subthalamic nucleus and its relation todopaminergic response in Parkinson’s disease
    • Weinberger MMN, Hutchison WD, Lozano AM, et al. Beta oscillatory activity in the subthalamic nucleus and its relation todopaminergic response in Parkinson’s disease. J Neurophysiol. 2006;96:3248–3256.
    • (2006) J Neurophysiol , vol.96 , pp. 3248-3256
    • Weinberger, M.M.N.1    Hutchison, W.D.2    Lozano, A.M.3
  • 108
    • 58249106127 scopus 로고    scopus 로고
    • Pathological synchronisation in the subthalamic nucleus of patients with Parkinson’s disease relates to both bradykinesia and rigidity
    • Kuhn AA, Tsui A, Aziz T, et al. Pathological synchronisation in the subthalamic nucleus of patients with Parkinson’s disease relates to both bradykinesia and rigidity. Exp Neurol. 2009;215:380–387.
    • (2009) Exp Neurol , vol.215 , pp. 380-387
    • Kuhn, A.A.1    Tsui, A.2    Aziz, T.3
  • 109
    • 33645459845 scopus 로고    scopus 로고
    • Reduction in subthalamic 8–35 Hzoscillatory activity correlates with clinical improvement in Parkinson’s disease
    • Kuhn AA, Kupsch A, Schneider GH, et al. Reduction in subthalamic 8–35 Hzoscillatory activity correlates with clinical improvement in Parkinson’s disease. Eur JNeurosci. 2006;23:1956–1960.
    • (2006) Eur JNeurosci , vol.23 , pp. 1956-1960
    • Kuhn, A.A.1    Kupsch, A.2    Schneider, G.H.3
  • 110
    • 34247241683 scopus 로고    scopus 로고
    • Excessive synchronization of basal ganglianeurons at 20 Hz slows movement in Parkinson’s disease
    • Chen CC, Litvak V, Gilbertson T, et al. Excessive synchronization of basal ganglianeurons at 20 Hz slows movement in Parkinson’s disease. Exp Neurol. 2007;205:214–221.
    • (2007) Exp Neurol , vol.205 , pp. 214-221
    • Chen, C.C.1    Litvak, V.2    Gilbertson, T.3
  • 111
    • 37549034710 scopus 로고    scopus 로고
    • Effects of low-frequency stimulation of the subthalamic nucleus on movement inParkinson’s disease
    • Eusebio A, Chen CC, Lu CS, et al. Effects of low-frequency stimulation of the subthalamic nucleus on movement inParkinson’s disease. Exp Neurol. 2008;209(1):125–130.
    • (2008) Exp Neurol , vol.209 , Issue.1 , pp. 125-130
    • Eusebio, A.1    Chen, C.C.2    Lu, C.S.3
  • 112
    • 0026517853 scopus 로고
    • Temporal discrimination is abnormal in Parkinson’s disease
    • Artieda J, Pastor MA, Lacruz F, et al. Temporal discrimination is abnormal in Parkinson’s disease. Brain. 1992;115:199–210.
    • (1992) Brain , vol.115 , pp. 199-210
    • Artieda, J.1    Pastor, M.A.2    Lacruz, F.3
  • 113
    • 77956380183 scopus 로고    scopus 로고
    • Subthalamic nucleus stimulation and somatosensory temporal discrimination in Parkinson’s disease
    • Conte A, Modugno N, Lena F, et al. Subthalamic nucleus stimulation and somatosensory temporal discrimination in Parkinson’s disease. Brain. 2010;133(9):2656–2663.
    • (2010) Brain , vol.133 , Issue.9 , pp. 2656-2663
    • Conte, A.1    Modugno, N.2    Lena, F.3
  • 114
    • 84875050399 scopus 로고    scopus 로고
    • Somatosensory temporal discrimination threshold may help to differentiate patients with multiple system atrophy from patients with Parkinson’s disease
    • Rocchi L, Conte A, Nardella A, et al. Somatosensory temporal discrimination threshold may help to differentiate patients with multiple system atrophy from patients with Parkinson’s disease. Eur J Neurol. 2013;20(4):714–719.
    • (2013) Eur J Neurol , vol.20 , Issue.4 , pp. 714-719
    • Rocchi, L.1    Conte, A.2    Nardella, A.3
  • 115
    • 34247238736 scopus 로고    scopus 로고
    • Abnormal temporal discrimination threshold in patients with multiple system atrophy
    • Mar
    • Lyoo CH, Lee SY, Song TJ, et al. Abnormal temporal discrimination threshold in patients with multiple system atrophy. Mov Disord. 2007 Mar 15;22(4):556–559.
    • (2007) Mov Disord , vol.22 , Issue.4 , pp. 556-559
    • Lyoo, C.H.1    Lee, S.Y.2    Song, T.J.3
  • 116
    • 84867103052 scopus 로고    scopus 로고
    • Striatal dopamine loss and discriminative sensory dysfunction in Parkinson’s disease
    • Lyoo CH, Ryu YH, Lee MJ, et al. Striatal dopamine loss and discriminative sensory dysfunction in Parkinson’s disease. Acta Neurol Scand. 2012;126:344–349.
    • (2012) Acta Neurol Scand , vol.126 , pp. 344-349
    • Lyoo, C.H.1    Ryu, Y.H.2    Lee, M.J.3
  • 117
    • 78349249737 scopus 로고    scopus 로고
    • Impaired finger dexterity in patients with Parkinson’s disease correlates with discriminative cutaneous sensory dysfunction
    • Lee MS, Lyoo CH, Lee MJ, et al. Impaired finger dexterity in patients with Parkinson’s disease correlates with discriminative cutaneous sensory dysfunction. Mov Disord. 2010;25:2531–2535.
    • (2010) Mov Disord , vol.25 , pp. 2531-2535
    • Lee, M.S.1    Lyoo, C.H.2    Lee, M.J.3
  • 118
    • 84892187093 scopus 로고    scopus 로고
    • Sensory aspects of movement disorders
    • Jan
    • Patel N, Jankovic J, Hallett M. Sensory aspects of movement disorders. Lancet Neurol. 2014 Jan;13(1):100–112.
    • (2014) Lancet Neurol , vol.13 , Issue.1 , pp. 100-112
    • Patel, N.1    Jankovic, J.2    Hallett, M.3
  • 119
    • 13844319729 scopus 로고    scopus 로고
    • Off” gait freezing and temporal discrimination threshold in patients with Parkinson disease
    • Lee MS, Kim HS, Lyoo CH. “Off” gait freezing and temporal discrimination threshold in patients with Parkinson disease. Neurology. 2005 22;64(4):670–674.
    • (2005) Neurology , vol.64 , Issue.4 , pp. 670-674
    • Lee, M.S.1    Kim, H.S.2    Lyoo, C.H.3
  • 120
    • 2942711637 scopus 로고    scopus 로고
    • Quantitative measurement of pain sensation in patients with Parkinson disease
    • Djaldetti R, Shifrin A, Rogowski Z, et al. Quantitative measurement of pain sensation in patients with Parkinson disease. Neurology. 2004;62:2171–2175.
    • (2004) Neurology , vol.62 , pp. 2171-2175
    • Djaldetti, R.1    Shifrin, A.2    Rogowski, Z.3
  • 121
    • 33644966535 scopus 로고    scopus 로고
    • Effect of levodopa on pain threshold in Parkinson’s disease: a clinical and positron emission tomography study
    • Brefel-Courbon C, Payoux P, Thalamas C, et al. Effect of levodopa on pain threshold in Parkinson’s disease:a clinical and positron emission tomography study. Mov Disord. 2005;20:1557–1563.
    • (2005) Mov Disord , vol.20 , pp. 1557-1563
    • Brefel-Courbon, C.1    Payoux, P.2    Thalamas, C.3
  • 122
    • 46849086581 scopus 로고    scopus 로고
    • Sensory deficit in Parkinson’s disease: evidence of a cutaneous denervation
    • Nolano M, Provitera V, Estraneo A, et al. Sensory deficit in Parkinson’s disease:evidence of a cutaneous denervation. Brain. 2008;131:1903–1911.
    • (2008) Brain , vol.131 , pp. 1903-1911
    • Nolano, M.1    Provitera, V.2    Estraneo, A.3
  • 123
    • 57049113204 scopus 로고    scopus 로고
    • Do dyskinesia and pain share common pathophysiological mechanisms in Parkinson’s disease?
    • Lim SY, Farrell MJ, Gibson SJ, et al. Do dyskinesia and pain share common pathophysiological mechanisms in Parkinson’s disease? Mov Disord. 2008(23):1689–1695.
    • (2008) Mov Disord , Issue.23 , pp. 1689-1695
    • Lim, S.Y.1    Farrell, M.J.2    Gibson, S.J.3
  • 124
    • 0020477318 scopus 로고
    • Dopaminergic effects on tail-flick response in spinal rats
    • Jensen TS, Smith DF. Dopaminergic effects on tail-flick response in spinal rats. Eur J Pharmacol. 1982;79:129–133.
    • (1982) Eur J Pharmacol , vol.79 , pp. 129-133
    • Jensen, T.S.1    Smith, D.F.2
  • 125
    • 0021359810 scopus 로고
    • Effects of an intrathecal dopamine agonist, apomorphine, on thermal and chemical evoked noxious responses in rats
    • Jensen TS, Yaksh TL. Effects of an intrathecal dopamine agonist, apomorphine, on thermal and chemical evoked noxious responses in rats. Brain Res. 1984;296:285–293.
    • (1984) Brain Res , vol.296 , pp. 285-293
    • Jensen, T.S.1    Yaksh, T.L.2
  • 126
    • 0023877854 scopus 로고    scopus 로고
    • Antinociceptive actions of descending dopaminergic tracts on cat and rat dorsal horn somatosensory neurones
    • Fleetwood-Walker SM, Hope PJ, Mitchell R. Antinociceptive actions of descending dopaminergic tracts on cat and rat dorsal horn somatosensory neurones. J Physiol. 1998;399:335–348.
    • (1998) J Physiol , vol.399 , pp. 335-348
    • Fleetwood-Walker, S.M.1    Hope, P.J.2    Mitchell, R.3
  • 127
    • 0026616865 scopus 로고
    • D2 dopamine receptor involvement in spinal dopamine-produced antinociception
    • Liu QS, Qiao JT, Dafny N. D2 dopamine receptor involvement in spinal dopamine-produced antinociception. Life Sci. 1992;51:1485–1492.
    • (1992) Life Sci , vol.51 , pp. 1485-1492
    • Liu, Q.S.1    Qiao, J.T.2    Dafny, N.3
  • 128
    • 0021012825 scopus 로고
    • Differential effects of SKF 38393 and LY 141865 on nociception and morphine analgesia
    • Ben-Sreti MM, Gonzalez JP, Sewell RD. Differential effects of SKF 38393 and LY 141865 on nociception and morphine analgesia. Life Sci. 1983;33(Suppl 1):665–668.
    • (1983) Life Sci , vol.33 , pp. 665-668
    • Ben-Sreti, M.M.1    Gonzalez, J.P.2    Sewell, R.D.3
  • 129
    • 0031978937 scopus 로고    scopus 로고
    • Dopamine receptor antagonists in the nucleus accumbens attenuate analgesia induced by ventral tegmental area substance P or morphine and by nucleus accumbens amphetamine
    • Altier N, Stewart J. Dopamine receptor antagonists in the nucleus accumbens attenuate analgesia induced by ventral tegmental area substance P or morphine and by nucleus accumbens amphetamine. J Pharmaco Lexpther. 1998;285:208–215.
    • (1998) J Pharmaco Lexpther , vol.285 , pp. 208-215
    • Altier, N.1    Stewart, J.2
  • 130
    • 0034645904 scopus 로고    scopus 로고
    • The involvement of dopamine in nociception: the role of D(1) and D(2) receptors in the dorsolateral striatum
    • Magnusson JE, Fisher K. The involvement of dopamine in nociception:the role of D(1) and D(2) receptors in the dorsolateral striatum. Brain Res. 2000;855:260–266.
    • (2000) Brain Res , vol.855 , pp. 260-266
    • Magnusson, J.E.1    Fisher, K.2
  • 131
    • 0036711077 scopus 로고    scopus 로고
    • Dopamine D2 receptor binding in the human brain is associated with the response to painful stimulation and pain modulatory capacity
    • Hagelberg N, Martikainen IK, Mansikka H, et al. Dopamine D2 receptor binding in the human brain is associated with the response to painful stimulation and pain modulatory capacity. Pain. 2002;99:273–279.
    • (2002) Pain , vol.99 , pp. 273-279
    • Hagelberg, N.1    Martikainen, I.K.2    Mansikka, H.3
  • 132
    • 4644242446 scopus 로고    scopus 로고
    • Striatal dopamine D2/D3 receptor availability correlates with individual response characteristics to pain
    • Pertovaara A, Martikainen IK, Hagelberg N, et al. Striatal dopamine D2/D3 receptor availability correlates with individual response characteristics to pain. Eur J Neurosci. 2004;20:1587–1592.
    • (2004) Eur J Neurosci , vol.20 , pp. 1587-1592
    • Pertovaara, A.1    Martikainen, I.K.2    Hagelberg, N.3
  • 133
    • 13844253844 scopus 로고    scopus 로고
    • Association of striatal dopamine D2/D3 receptor binding potential with pain but not tactile sensitivity or placebo analgesia
    • Martikainen IK, Hagelberg N, Mansikka H, et al. Association of striatal dopamine D2/D3 receptor binding potential with pain but not tactile sensitivity or placebo analgesia. Neurosci Lett. 2005;376:149–153.
    • (2005) Neurosci Lett , vol.376 , pp. 149-153
    • Martikainen, I.K.1    Hagelberg, N.2    Mansikka, H.3
  • 134
    • 33750965981 scopus 로고    scopus 로고
    • Variations in the human pain stress experience mediated by ventral and dorsal basal ganglia dopamine activity
    • Scott DJ, Heitzeg MM, Koeppe RA, et al. Variations in the human pain stress experience mediated by ventral and dorsal basal ganglia dopamine activity. J Neurosci. 2006;26:10789–10795.
    • (2006) J Neurosci , vol.26 , pp. 10789-10795
    • Scott, D.J.1    Heitzeg, M.M.2    Koeppe, R.A.3
  • 135
    • 34547156155 scopus 로고    scopus 로고
    • Timecourse of change in [11C]carfentanil and [11C]raclopride binding potential after a nonpharmacological challenge
    • Scott DJ, Stohler CS, Koeppe RA, et al. Timecourse of change in [11C]carfentanil and [11C]raclopride binding potential after a nonpharmacological challenge. Synapse. 2007;61:707–714.
    • (2007) Synapse , vol.61 , pp. 707-714
    • Scott, D.J.1    Stohler, C.S.2    Koeppe, R.A.3
  • 136
    • 41749089836 scopus 로고    scopus 로고
    • Abnormal processing of the nociceptive input in Parkinson’s disease: a study with CO2 laser evoked potentials
    • Tinazzi M, Del Vesco C, Defazio G, et al. Abnormal processing of the nociceptive input in Parkinson’s disease:a study with CO2 laser evoked potentials. Pain. 2008;136:117–124.
    • (2008) Pain , vol.136 , pp. 117-124
    • Tinazzi, M.1    Del Vesco, C.2    Defazio, G.3
  • 137
    • 0037356246 scopus 로고    scopus 로고
    • Sensorimotorintegration in movementdisorders
    • Mar
    • Abbruzzese G, Berardelli A. Sensorimotorintegration in movementdisorders. Mov Disord. 2003 Mar;18(3):231–240.
    • (2003) Mov Disord , vol.18 , Issue.3 , pp. 231-240
    • Abbruzzese, G.1    Berardelli, A.2
  • 138
    • 20244367440 scopus 로고    scopus 로고
    • Effects of lorazepam on short latency afferent inhibition and short latency intracortical inhibition in humans
    • Di Lazzaro V, Oliviero A, Saturno E, et al. Effects of lorazepam on short latency afferent inhibition and short latency intracortical inhibition in humans. J Physiol. 2005;564:661–668.
    • (2005) J Physiol , vol.564 , pp. 661-668
    • Di Lazzaro, V.1    Oliviero, A.2    Saturno, E.3
  • 139
    • 0043268768 scopus 로고    scopus 로고
    • Short and long latency afferent inhibition in Parkinson’s disease
    • Sailer A, Molnar GF, Paradiso G, et al. Short and long latency afferent inhibition in Parkinson’s disease. Brain. 2003;126:1883–1894.
    • (2003) Brain , vol.126 , pp. 1883-1894
    • Sailer, A.1    Molnar, G.F.2    Paradiso, G.3
  • 140
    • 0022967012 scopus 로고
    • Scaling of the size of the first agonist EMG burst during rapid wrist movements in patients with Parkinson’s disease
    • Berardelli A, Dick JP, Rothwell JC, et al. Scaling of the size of the first agonist EMG burst during rapid wrist movements in patients with Parkinson’s disease. J Neurol Neurosurg Psychiatry. 1986;49:1273–1279.
    • (1986) J Neurol Neurosurg Psychiatry , vol.49 , pp. 1273-1279
    • Berardelli, A.1    Dick, J.P.2    Rothwell, J.C.3
  • 141
    • 84927976255 scopus 로고    scopus 로고
    • Dopaminergic modulation of motor network dynamics in Parkinson’s disease
    • Michely J, Volz LJ, Barbe MT, et al. Dopaminergic modulation of motor network dynamics in Parkinson’s disease. Brain. 2015;138(Pt 3):664–678.
    • (2015) Brain , vol.138 , pp. 664-678
    • Michely, J.1    Volz, L.J.2    Barbe, M.T.3
  • 142
    • 56749186799 scopus 로고    scopus 로고
    • Functional role of the supplementary and pre-supplementary motor areas
    • Nachev P, Kennard C, Husain M. Functional role of the supplementary and pre-supplementary motor areas. Nat Rev Neurosci. 2008;9:856–869.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 856-869
    • Nachev, P.1    Kennard, C.2    Husain, M.3
  • 143
    • 80053392366 scopus 로고    scopus 로고
    • Neural circuits of the cerebellum: hypothesis for function
    • D’Angelo E. Neural circuits of the cerebellum:hypothesis for function. J Integr Neurosci. 2011;10:317–52.31.
    • (2011) J Integr Neurosci , vol.10 , pp. 317-352
    • D’Angelo, E.1
  • 144
    • 84924794997 scopus 로고    scopus 로고
    • Are studies of motor cortex plasticity relevant in human patients with Parkinson’s disease?
    • Bologna M, Suppa A, Conte A, et al. Are studies of motor cortex plasticity relevant in human patients with Parkinson’s disease?. Clin Neurophysiol. 2016;127(1):50–59.•• This review focuses on the effect of drugs including L-Dopa on various TMS paradigms testing primary motor cortex excitability in humans.
    • (2016) Clin Neurophysiol , vol.127 , Issue.1 , pp. 50-59
    • Bologna, M.1    Suppa, A.2    Conte, A.3
  • 145
    • 0035005945 scopus 로고    scopus 로고
    • D1 dopamine receptors potentiate NMDA-mediated excitability increase in layer V prefrontal cortical pyramidal neurons
    • Wang J, O’Donnell P. D1 dopamine receptors potentiate NMDA-mediated excitability increase in layer V prefrontal cortical pyramidal neurons. Cereb Cortex. 2001;11:452–462.
    • (2001) Cereb Cortex , vol.11 , pp. 452-462
    • Wang, J.1    O’Donnell, P.2
  • 146
    • 70349400360 scopus 로고    scopus 로고
    • Dopamine in motor cortex is necessary for skill learning and synaptic plasticity
    • Molina-Luna K, Pekanovic A, Röhrich S, et al. Dopamine in motor cortex is necessary for skill learning and synaptic plasticity. PLoS One. 2009;4:e7082.
    • (2009) PLoS One , vol.4 , pp. 7082
    • Molina-Luna, K.1    Pekanovic, A.2    Röhrich, S.3
  • 147
    • 84885335102 scopus 로고    scopus 로고
    • Dopaminergic meso-cortical projections to M1: role in motor learning and motor cortex plasticity
    • Hosp JA, Luft AR. Dopaminergic meso-cortical projections to M1:role in motor learning and motor cortex plasticity. Front Neurol. 2013;4:145.
    • (2013) Front Neurol , vol.4 , pp. 145
    • Hosp, J.A.1    Luft, A.R.2
  • 149
    • 0031892817 scopus 로고    scopus 로고
    • Cortical networks underlying mechanisms of time perception
    • Harrington DL, Haaland KY, Knight RT. Cortical networks underlying mechanisms of time perception. J Neurosci. 1998 1;18(3):1085–1095.
    • (1998) J Neurosci , vol.18 , Issue.3 , pp. 1085-1095
    • Harrington, D.L.1    Haaland, K.Y.2    Knight, R.T.3
  • 150
    • 0030464024 scopus 로고    scopus 로고
    • The representation of temporal information in perception and motor control
    • Ivry RB. The representation of temporal information in perception and motor control. Curr Opin Neurobiol. 1996;6(6):851–857.
    • (1996) Curr Opin Neurobiol , vol.6 , Issue.6 , pp. 851-857
    • Ivry, R.B.1
  • 152
    • 9144249598 scopus 로고    scopus 로고
    • The origin of motor fluctuations in Parkinson’s disease: importance of dopaminergic innervation and basal ganglia circuits
    • Obeso JA, Rodriguez-Oroz M, Marin C, et al. The origin of motor fluctuations in Parkinson’s disease:importance of dopaminergic innervation and basal ganglia circuits. Neurology. 2004 13;62(1 Suppl 1):S17–S30.
    • (2004) Neurology , vol.62 , Issue.1 , pp. S17-S30
    • Obeso, J.A.1    Rodriguez-Oroz, M.2    Marin, C.3
  • 153
    • 0033967459 scopus 로고    scopus 로고
    • Cortical motor reorganization in akinetic patients with Parkinson’s disease: a functional MRI study
    • Sabatini U, Boulanouar K, Fabre N, et al. Cortical motor reorganization in akinetic patients with Parkinson’s disease:a functional MRI study. Brain. 2000;123(Pt 2):394–403.
    • (2000) Brain , vol.123 , pp. 394-403
    • Sabatini, U.1    Boulanouar, K.2    Fabre, N.3
  • 154
    • 72849153163 scopus 로고    scopus 로고
    • Mapping preclinical compensation in Parkinson’s disease: an imaging genomics approach
    • van Nuenen BF, van Eimeren T, van der Vegt JP, et al. Mapping preclinical compensation in Parkinson’s disease:an imaging genomics approach. Mov Disord. 2009;24(Suppl 2):S703–S710.
    • (2009) Mov Disord , vol.24 , pp. S703-S710
    • van Nuenen, B.F.1    van Eimeren, T.2    van der Vegt, J.P.3
  • 155
    • 0030687682 scopus 로고    scopus 로고
    • Do compensatory processes underlie the preclinical phase of neurodegenerative disease? Insights from an animal model of parkinsonism
    • Zigmond MJ. Do compensatory processes underlie the preclinical phase of neurodegenerative disease? Insights from an animal model of parkinsonism. Neurobiol Dis. 1997;4(3–4):247–253.
    • (1997) Neurobiol Dis , vol.4 , Issue.3-4 , pp. 247-253
    • Zigmond, M.J.1
  • 156
    • 84887404219 scopus 로고    scopus 로고
    • How pain arises in Parkinson’s disease?
    • Dec
    • Defazio G, Tinazzi M, Berardelli A. How pain arises in Parkinson’s disease? Eur J Neurol. 2013 Dec;20(12):1517–1523.
    • (2013) Eur J Neurol , vol.20 , Issue.12 , pp. 1517-1523
    • Defazio, G.1    Tinazzi, M.2    Berardelli, A.3
  • 157
    • 84873737898 scopus 로고    scopus 로고
    • Fatigue in Parkinson’s disease: motor or non-motor symptom?
    • Fabbrini G, Latorre A, Suppa A, et al. Fatigue in Parkinson’s disease:motor or non-motor symptom? Parkinsonism Relat Disord. 2013;19:148–152.
    • (2013) Parkinsonism Relat Disord , vol.19 , pp. 148-152
    • Fabbrini, G.1    Latorre, A.2    Suppa, A.3
  • 158
    • 84957842197 scopus 로고    scopus 로고
    • Sensory abnormalities and pain in Parkinson disease and its modulation by treatment of motor symptoms
    • Cury RG, Galhardoni R, Fonoff ET, et al. Sensory abnormalities and pain in Parkinson disease and its modulation by treatment of motor symptoms. Eur J Pain. 2016;20(2):151–165.
    • (2016) Eur J Pain , vol.20 , Issue.2 , pp. 151-165
    • Cury, R.G.1    Galhardoni, R.2    Fonoff, E.T.3
  • 159
    • 84885410674 scopus 로고    scopus 로고
    • The role of dopamine in the perceptual modulation of nociceptive stimuli by monetary wins or losses
    • Becker S, Gandhi W, Elfassy NM, et al. The role of dopamine in the perceptual modulation of nociceptive stimuli by monetary wins or losses. Eur J Neurosci. 2013;38:3080–3088.
    • (2013) Eur J Neurosci , vol.38 , pp. 3080-3088
    • Becker, S.1    Gandhi, W.2    Elfassy, N.M.3


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