Dopamine D2 receptor binding in the human brain is associated with the response to painful stimulation and pain modulatory capacity

Pain

Volumn 99, Issue 1-2, 2002, Pages 273-279

  Hagelberg, Nora ^a   Martikainen, Ilkka K ^a   Mansikka, Heikki ^a   Hinkka, Susanna ^a   Någren, Kjell ^a   Hietala, Jarmo ^a   Scheinin, Harry ^a   Pertovaara, Antti ^a  

^a UNIVERSITY OF TURKU   (Finland)

Author keywords

Cold pressor pain; Dopamine D2 receptor; Pain modulation; Positron emission tomography

Indexed keywords

CARBON 11; DOPAMINE 2 RECEPTOR; ICE; ISOREMOXIPRIDE; RACLOPRIDE; RADIOLIGAND; WATER;

ADULT; ARTICLE; BINDING AFFINITY; BRAIN REGION; CLINICAL TRIAL; COLD; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DOPAMINERGIC SYSTEM; HAND; HEALTH STATUS; HEAT; HUMAN; LATENT PERIOD; MALE; NORMAL HUMAN; PAIN; PAIN THRESHOLD; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PSYCHOPHYSIOLOGY; RECEPTOR BINDING; VOLUNTEER;

ADULT; BRAIN; CARBON RADIOISOTOPES; COLD; CONDITIONING (PSYCHOLOGY); DOPAMINE ANTAGONISTS; HUMANS; MALE; PAIN; PAIN THRESHOLD; PSYCHOPHYSICS; RACLOPRIDE; RECEPTORS, DOPAMINE D2; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0036711077     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(02)00121-5     Document Type: Article

References (53)

1. Akil H., Liebeskind J.C. Monoaminergic mechanisms of stimulation-produced analgesia. Brain Res. 94:1975;279-296.
2. Altier N., Stewart J. Dopamine receptor antagonists in the nucleus accumbens attenuate analgesia induced by ventral tegmental area substance P or morphine and by nucleus accumbens amphetamine. J Pharmacol Exp Ther. 285:1998;208-215.
3. Altier N., Stewart J. The role of dopamine in the nucleus accumbens in analgesia. Life Sci. 65:1999;2269-2287.
4. Barasi S., Ben-Sreti M.M., Clatworthy A.L., Duggal K.N., Gonzalez J.P., Robertson J., Rooney K.F., Sewell R.D. Dopamine receptor-mediated spinal antinociception in the normal and haloperidol pretreated rat: effects of sulpiride and SCH 23390. Br J Pharmacol. 90:1987;15-22.
5. Ben-Sreti M.M., Gonzalez J.P., Sewell R.D. Differential effects of SKF 38393 and LY 141865 on nociception and morphine analgesia. Life Sci. 33:(Suppl 1):1983;665-668.
6. Breier A., Kestler L., Adler C., Elman I., Wiesenfeld N., Malhotra A., Pickar D. Dopamine D2 receptor density and personal detachment in healthy subjects. Am J Psychiatry. 155:1998;1440-1442.
7. Chudler E.H. Response properties of neurons in the caudate-putamen and globus pallidus to noxious and non-noxious thermal stimulation in anesthetized rats. Brain Res. 812:1998;283-288.
8. Chudler E.H., Dong W.K. The role of the basal ganglia in nociception and pain. Pain. 60:1995;3-38.
9. Coghill R.C., Sang C.N., Maisog J.M., Iadarola M.J. Pain intensity processing within the human brain: a bilateral, distributed mechanism. J Neurophysiol. 82:1999;1934-1943.
10. Dennis S.G., Melzack R. Effects of cholinergic and dopaminergic agents on pain and morphine analgesia measured by three pain tests. Exp Neurol. 81:1983;167-176.
11. 11C-raclopride is altered by drugs that modify synaptic dopamine levels. Synapse. 13:1993;350-356.
12. Ertas M., Sagduyu A., Arac N., Uludag B., Ertekin C. Use of levodopa to relieve pain from painful symmetrical diabetic polyneuropathy. Pain. 75:1995;257-259.
13. 11C]raclopride in man. Synapse. 20:1995;200-208.
14. Farde L., Gustavsson J.P., Jonsson E. D2 dopamine receptors and personality traits. Nature. 385:1997;590.
15. Fleetwood-Walker S.M., Hope P.J., Mitchell R. Antinociceptive actions of descending dopaminergic tracts on cat and rat dorsal horn somatosensory neurones. J Physiol (Lond). 399:1988;335-348.
16. Gear R.W., Aley K.O., Levine J.D. Pain-induced analgesia mediated by mesolimbic reward circuits. J Neurosci. 19:1999;7175-7181.
17. Goetz C.G., Tanner C.M., Levy M., Wilson R.S., Garron D.C. Pain in Parkinson's disease. Mov Disord. 1:1986;45-49.
18. Hall H., Sedvall G., Magnusson O., Kopp J., Halldin C., Farde L. Distribution of D1- and D2-dopamine receptors, and dopamine and its metabolites in the human brain. Neuropsychopharmacology. 11:1994;245-256.
19. Hietala J., Syvälahti E., Vuorio K., Någren K., Lehikoinen P., Ruotsalainen U., Räkköläinen V., Lehtinen V., Wegelius U. Striatal D2 dopamine receptor characteristics in neuroleptic-naive schizophrenic patients studied with positron emission tomography. Arch Gen Psychiatry. 51:1994;116-123.
20. 11C]-raclopride in vivo: a test-retest analysis. J Cereb Blood Flow Metab. 19:1999;210-217.
21. Jääskeläinen S., Rinne J.O., Forssell H., Tenovuo O., Kaasinen V., Sonninen P., Bergman J. Role of the dopaminergic system in chronic pain - a fluorodopa-PET-study. Pain. 90:2001;257-260.
22. Jensen T.S., Smith D.F. Dopaminergic effects on tail-flick responses in spinal rats. Eur J Pharmacol. 79:1982;129-133.
23. Jensen T.S., Yaksh T.L. Effects of an intrathecal dopamine agonist, apomorphine, on thermal and chemical evoked noxious responses in rats. Brain Res. 296:1984;285-293.
24. Jones A.K.P., Brown W.D., Friston K.J., Qi L.Y., Frackowiak R.S.J. Cortical and subcortical localization of response to pain in man using positron emission tomography. Proc R Soc Lond. 244:1991;39-44.
25. Kaasinen V., Någren K., Hietala J., Farde L., Rinne J.O. Sex differences in extrastriatal dopamine D2-like receptors in the human brain. Am J Psychiatry. 158:2001;308-311.
26. Kernbaum S., Hauchecorne J. Administration of levodopa for relief of herpes zoster pain. J Am Med Assoc. 246:1981;132-134.
27. Khan Z.U., Gutierrez A., Martin R., Penafiel A., Rivera A., de la Calle A. Differential regional and cellular distribution of dopamine D2-like receptors: an immunocytochemical study of subtype-specific antibodies in rat and human brain. J Comp Neurol. 402:1998;353-371.
28. Koller W.C. Sensory symptoms in Parkinson's disease. Neurology. 34:1984;957-959.
29. Lammertsma A.A., Hume S.P. Simplified reference tissue model for PET studies. Neuroimage. 4:1996;153-158.
30. Laruelle M. Imaging synaptic neurotransmission with in vivo binding competition techniques: a critical review. J Cereb Blood Flow Metab. 20:2000;423-451.
31. Lin M.T., Wu J.J., Chandra A., Tsay B.L. Activation of striatal dopamine receptors induces pain inhibition in rats. J Neural Transm. 51:1981;213-222.
32. Lin M.T., Wu J.J., Tsay B.L. Effects of kainic acid injections in the striatum on physiologic and behavioural functions in conscious rats. Exp Neurol. 83:1984;71-83.
33. Lin Y., Morrow T.J., Kiritsy-Roy J.A., Terry L.C., Casey K.L. Cocaine: evidence for supraspinal, dopamine-mediated non-opiate analgesia. Brain Res. 479:1989;306-312.
34. Liu Q.S., Qiao J.T., Dafny N. D2 dopamine receptor involvement in spinal dopamine-produced antinociception. Life Sci. 51:1992;1485-1492.
35. 11C]methyl triflate. J Label Compd Radiopharm. 41:1998;545-556.
36. 2 receptors in the dorsolateral striatum. Brain Res. 855:2000;260-266.
37. Michael-Titus A., Bousselmame R., Costentin J. Stimulation of dopamine D2 receptors induces analgesia involving an opioidergic but not enkephalinergic link. Eur J Pharmacol. 187:1990;201-207.
38. Morgan M.J., Franklin K.B. Dopamine receptor subtypes and formalin test analgesia. Pharmacol Biochem Behav. 40:1991;317-322.
39. 11C]raclopride binding in healthy-young adults and schizophrenic - patients-Reliability and age effects. Hum Psychopharmacol. 7:1992;157-165.
40. 11C]FLB 457 binding to extrastriatal dopamine receptors in the human brain. J Cereb Blood Flow Metab. 19:1999;1164-1173.
41. Paalzow G.H., Paalzow L.K. Opposing effects of apomorphine on pain in rats. Evaluation of the dose-response curve. Eur J Pharmacol. 88:1983;27-35.
42. Peckerman A., Saab P.G., McCabe P.M., Skyler J.S., Winters R.W., Llabre M.M., Schneiderman N. Blood pressure reactivity and perception of pain during the forehead cold pressor test. Psychophysiology. 28:1991;485-495.
43. Pertovaara A., Kemppainen P., Johansson G., Karonen S.L. Ischemic pain nonsegmentally produces a predominant reduction of pain and thermal sensitivity in man: a selective role for endogenous opioids. Brain Res. 251:1982;83-92.
44. Pohjalainen T., Rinne J.O., Någren K., Syvälahti E., Hietala J. Sex differences in the striatal dyopamine D2 receptor binding characteristics in vivo. Am J Psychiatry. 155:1998;768-773.
45. Pohjalainen T., Rinne J.O., Någren K., Lehikoinen P., Anttila K., Syvälahti E., Hietala J. The A1 allele of the human D2 dopamine receptor gene predicts low striatal D2 receptor availability in healthy volunteers. Mol Psychiatry. 3:1998;256-260.
46. Rainville P., Feine J.S., Bushnell M.C., Duncan G.H. A psychophysical comparison of sensory and affective responses to four modalities of experimental pain. Somatosens Mot Res. 9:1992;265-277.
47. Saade N.E., Atweh S.F., Bahuth N.B., Jabbur S.J. Augmentation of nociceptive reflexes and chronic differentiation pain by chemical lesions of either dopaminergic terminals or midbrain dopaminergic neurons. Brain Res. 751:1997;1-12.
48. Schott G.D. Pain in Parkinson's disease. Pain. 22:1985;407-411.
49. Suhara T., Yasuno F., Sudo Y., Yamamoto M., Inoue M., Okubo Y., Suzuki K. Dopamine D2 receptors in the insular cortex and the personality trait of novelty seeking. Neuroimage. 13:2001;891-895.
50. 11C]FLB 457 binding in extrastriatal regions. Nuclear Med Commun. 22:2001;1215-1221.
51. Talbot J.D., Duncan G.H., Bushnell M.C., Boyer M. Diffuse noxious inhibitory controls (DNICs): psychophysical evidence in man for intersegmental suppression of noxious heat perception by cold pressure pain. Pain. 30:1987;221-232.
52. 11C]FLB 457 - a test-retest analysis. Eur J Nucl Med. 27:2000;1666-1673.
53. Willer J.C., Roby A., Le Bars D. Psychophysical and electrophysiological approaches to the pain-relieving effects of heterotopic nociceptive stimuli. Brain. 107:1984;1095-1112.