Dopamine receptor antagonists in the nucleus accumbens attenuate analgesia induced by ventral tegmental area substance P or morphine and by nucleus accumbens amphetamine

Journal of Pharmacology and Experimental Therapeutics

Volumn 285, Issue 1, 1998, Pages 208-215

  Altier, Nadège ^a   Stewart, Jane ^a  

^a and Applied Physiology   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; AMPHETAMINE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; FLUPENTIXOL; FORMALDEHYDE; MORPHINE; OPIATE; RACLOPRIDE; SUBSTANCE P; SUBSTANCE P DERIVATIVE;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; DRUG MECHANISM; LOCOMOTION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; VENTRAL TEGMENTUM;

(R)-2,3,4,5-TETRAHYDRO-8-CHLORO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL; ADRENERGIC ANTAGONISTS; AMPHETAMINE; ANALGESIA; ANALGESICS, OPIOID; ANIMALS; DOPAMINE ANTAGONISTS; FLUPENTHIXOL; MALE; MORPHINE; NUCLEUS ACCUMBENS; PEPTIDE FRAGMENTS; PYRROLIDONECARBOXYLIC ACID; RACLOPRIDE; RATS; RATS, WISTAR; SALICYLAMIDES; SUBSTANCE P; VENTRAL TEGMENTAL AREA;

EID: 0031978937     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Altier N (1993) The Role of Midbrain Substance P in Stress-Induced Analgesia using the Formalin Test for Tonic Pain. Master's Thesis, Concordia University, Montreal, Québec, Canada.
2. Altier N and Stewart J (1993) Intra-VTA infusions of the substance P analogue, DiMe-C7, and intra-accumbens infusions of amphetamine induce analgesia in the formalin test for tonic pain. Brain Res 628:279-285.
3. Altier N and Stewart J (1996) Opioid receptors in the ventral tegmental area contribute to stress-induced analgesia in the formalin test for tonic pain. Brain Res 718:203-206.
4. Altier N and Stewart J (1997) Tachykinin NK-1 and NK-3 selective agonists induce analgesia in the formalin test for tonic pain following intra-VTA or intra-accumbens microinfusions. Behav Brain Res 89:151-165.
5. Anderson RM and Rompré PP (1996) Rewarding electrical stimulation of the ventral tegmental area attenuates pain during the formalin test. Soc Neurosci Abstr 22:686.
6. Bals-Kubik R, Ableitner A, Herz A and Shippenberg TS (1993) Neuroanatomical sites mediating the motivational effects of opioids as mapped by the conditioned place preference paradigm in rats. J Pharmacol Exp Ther 264:489-495.
7. Boix F, Huston JP and Schwarting RKW (1992b) Effects of C-and N-terminal sequences of substance P on in vivo dopamine release in the neostriatum and nucleus accumbens. Brain Res 592:181-597.
8. Boix F, Mattioli R, Adams F, Huston JP and Schwarting RKW (1992a) Effects of substance P on extracellular dopamine in neostriatum and nucleus accumbens. Eur J Pharmacol 216:103-107.
9. Cador M, Rivet J-M, Kelley AE, Le Moal M and Stinus L (1989) Substance P, neurotensin and enkephalin injections into the ventral tegmental area: Comparative study on dopamine turnover in several forebrain structures. Brain Res 486:357-363.
10. Carr GD and White NM (1983) Conditioned place preference from intra-accumbens but not intra-caudate amphetamine injections. Life Sci 33:2551-2557.
11. Carr KD (1984) Dopaminergic mechanisms in the supraspinal modulation of pain, Pain (Suppl.) 2:S223.
12. Castaneda E, Whishaw IQ and Robinson TE (1990) Changes in striatal dopamine neurotransmission assessed with microdialysis following recovery from a bilateral 6-OHDA lesion: Variation as a function of lesion size. J Neurosci 10:1847-1854.
13. Clarke PBS and Franklin KBJ (1992) Infusions of 6-hydroxydopamine into the nucleus accumbens abolish the analgesic effect of amphetamine but not of morphine in the formalin test. Brain Res 580:106-110.
14. Coderre TJ, Fundytus ME, McKenna JF, Dalai S and Melzack R (1993) The formalin test: A validation of the weighted-scores method of behavioral pain rating. Pain 54:43-50.
15. Cohen RS and Melzack R (1985) Morphine injected into the habenula and dorsal posteromedial thalamus produces analgesia in the formalin test. Brain Res 359: 131-139.
16. Di Chiara G and Imperato A (1988) Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci USA 85:5274-5278.
17. Eison AS, Eison MS and Iversen SD (1982) The behavioral effects of a novel substance P analogue following infusion into the ventral tegmental area or substantia nigra of rat brain. Brain Res 238:137-152
18. Elliott PJ, Alpert JE, Bannon MJ and Iversen SD (1986) Selective activation of mesolimbic and mesocortical dopamine metabolism in rat brain by infusion of a stable substance P analogue into the ventral tegmental area. Brain Res 363:145-147.
19. Elliott PJ and Iversen SD (1986) Behavioral effects of tachykinins and related peptides. Brain Res 381:68-76.
20. Elliott PJ, Mason GS, Stephens-Smith M and Hagan RM (1991) Behavioral and biochemical responses following activation of midbrain dopamine pathways by receptor selective neurokinin agonists. Neuropeptides 19:119-126.
21. Franklin KBJ (1989) Analgesia and the neural substrate of reward, Neurosci Biohehav Rev 13:149-154.
22. Hoebel BG, Monaco AP, Hernandez L. Aulisi EF, Stanley BG and Lenard L (1983) Self-injection of amphetamine directly into the brain. Psychopharmacology 81: 158-163.
23. Joyce EM, Koob GF, Strecker R, Iversen SD and Bloom FE (1981) The behavioral effects of enkephalin analogues injected into the ventral tegmental area and globus pallidus. Brain Res 221:359-370.
24. Kalivas PW (1985) Interactions between neuropeptides and dopamine neurons in the ventromedial mesencephalon. Neurosci Biobehav Rev 9:573-587.
25. Kalivas PW and Richardson-Carlson R (1986) Endogeneous enkephalin modulation of dopamine neurons in the ventral tegmental area. Am J Physiol 258:243-249.
26. Kalivas PW, Widerlov E, Stanley D, Breese G and Prange AJ Jr (1983) Enkephalin action on the mesolimbic dopamine system: A dopamine-dependent and a dopamine-independent increase in locomotor activity. J Pharmacol Exp Ther 227:229-237.
27. Kelly PH and Iversen SD (1976) Selective 6OHDA-induced destruction of mesolimbic dopamine neurons: Abolition of psychostimulant-induced locomotor activity in rats. Ear J Pharmacol 40:45-56.
28. Kelly PH, Seviour PW and Iversen SD (1975) Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum. Brain Res 94:507-522.
29. Kelley AE, Stinus L and Iversen SD (1979) Behavioral activation induced in the rat by substance P infusion into the ventral tegmental area: Implication of dopaminergic A10 neurons. Neurosci Lett 11:335-339.
30. Kelsey JE, Carlezon WA Jr and Falls WA (1989) Lesions of the nucleus accumbens in rats reduce opiate reward but do not alter context-specific opiate tolerance. Behav Neurosci 103:1327-1334.
31. Kiyatkin EA, Wise RA and Gratton A (1993) Drug-and behavior-associated changes in dopamine-related electrochemical signals during intravenous heroin self-administration in rats. Synapse 14:60-72.
32. Latimer LG, Duffy P and Kalivas PW (1987) Mu opioid receptor involvement in enkephalin activation of dopamine neurons in the ventral tegmental area. J Pharmacol Exp Ther 241:328-337.
33. Lin Y, Morrow TJ, Kiritsy-Roy JA, Cass Terry L and Casey KL (1989) Cocaine: Evidence for supraspinal, dopamine-mediated, non-opiate analgesia. Brain Res 479:306-312.
34. Lyness WH, Friedle NM and Moore KE (1979) Destruction of dopaminergic nerve terminals in nucleus accumbens: effect on d-amphetamine self-administration. Pharmacol Biochem Behav 11:553-556.
35. Malmberg AB and Yaksh TL (1993) Pharmacology of the spinal action of ketorolac, morphine, ST-91, U50 488H, and L-PIA on the formalin test and an isobolographic analysis of the NSAID interaction. Anesthesiology 79:270-281.
36. Manning BH, Morgan MJ and Franklin KBJ (1994) Morphine analgesia in the formalin test: Evidence for forebrain and midbrain sites of action. Neuroscience 63:289-294.
37. Matthies BK and Franklin KBJ (1992) Formalin pain is expressed in decerebrate rats but not attenuated by morphine. Pain 51:199-206.
38. Morgan MJ and Franklin KBJ (1990) 6-Hydroxydopamine lesions of the ventral tegmentum abolish (+)-amphetamine and morphine analgesia in the formalin test but not the tail flick test. Brain Res 519:144-149.
39. Morgan MJ and Franklin KBJ (1991) Dopamine receptor subtypes and formalin test analgesia. Pharmacol Biochem Behav 40:317-322.
40. Nakajima S and Wise RA (1987) Heroin self-administration in the rat suppressed by SCH 23390. Soc Neurosci Abstr 13:1545.
41. Paalzow G and Paalzow L (1975) Morphine-induced inhibition of different pain responses in relation to the regional turnover of rat brain noradrenaline and dopamine. Psychopharmacology 45:9-20.
42. Paxinos G and Watson C (1986) The Rat Brain in Stereotaxic Coordinates. Academic Press, Orlando, Florida.
43. Pellegrino LJ, Pellegrino AS and Cushman AJ (1967) A Stereotaxic Atlas of the Rat Brain, Plenum Press, New York.
44. Phillips AG and LePiane FG (1980) Reinforcing effect of morphine microinjection into the ventral tegmental area. Pharmacol Biochem Behav 12:965-968.
45. Phillips GD, Robbins TW and Everitt BJ (1994) Bilateral intra-accumbens self-administration of d-amphetamine: Antagonism with intra-accumbens SCH-23390 and sulpiride. Psychopharmacology 114:477-485.
46. Pijnenburg AJJ, Honig WMM and Van Rossum JM (1975) Inhibition of d-amphetamine-induced locomotor activity by injection of haloperidol into the nucleus accumbens of the rat. Psychopharmacology 41:87-95.
47. Pijnenburg AJJ, Honig WMM, Van Der Heyden JAM and Van Rossum JM (1976) Effects of chemical stimulation of the mesolimbic dopamine system upon locomotor activity. Ear J Pharmacol 35:45-58.
48. Sharp T, Zetterstrom T, Ljungberg T and Ungerstedt U (1987) A direct comparison of amphetamine-induced behaviours and regional brain dopamine release in the rat using intracerebral dialysis. Brain Res 401:322-330.
49. Shippenberg TS, Bals-Kubik R and Herz A (1993) Examination of the neurochemical substrates mediating the motivational effects of opioids: Role of the mesolimbic dopamine system and D-1 vs. D-2 dopamine receptors. J Pharmacol Exp Ther 265:53-59.
50. Spanagle R, Herz A and Shippenberg TS (1990) The effects of opioid peptides on dopamine release in the nucleus accumbens: An in vivo microdialysis study. J Neurochem 55:1734-1740.
51. Stinus L, Kelley AE and Iversen SD (1978) Increased spontaneous activity following substance P infusion into A10 dopaminergic area. Nature 276:616-618.
52. Stinus L, Koob GF, Ling N, Bloom FE and LeMoal M (1980) Locomotor activation induced by infusion of endorphins into the ventral tegmental area: Evidence for opiate-dopamaine interactions. Proc Natl Acad Sci USA 4:2323-2327.
53. Vaccarino AL and Chorney DA (1994) Descending modulation of central neural plasticity in the formalin pain test. Brain Res 666:104-108.
54. van den Boss R, Cools AR and Ogren S-O (1988) Differential effects of the selective D2-antagonist raclopride in the nucleus accumbens of the rat on spontaneous and d-amphetamine-induced activity. Psychopharmacology 95:447-451.