Evaluation of the Tobacco Heating System 2.2. Part 2: Chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol

Regulatory Toxicology and Pharmacology

Volumn 81, Issue , 2016, Pages S27-S47

  Schaller, Jean Pierre ^a   Keller, Daniela ^a   Poget, Laurent ^a   Pratte, Pascal ^a   Kaelin, Etienne ^a   McHugh, Damian ^a   Cudazzo, Gianluca ^a   Smart, Daniel ^a   Tricker, Anthony R ^a   Gautier, Lydia ^a   Yerly, Michel ^a   Reis Pires, Roger ^a   Le Bouhellec, Soazig ^a   Ghosh, David ^a   Hofer, Iris ^a   Garcia, Eva ^a   Vanscheeuwijck, Patrick ^a   Maeder, Serge ^a  

^a PHILIP MORRIS PRODUCTS S A   (Switzerland)

Author keywords

Aerosol chemistry; Cytotoxicity; Harmful and potentially harmful constituents; Heat not burn; HPHC; Modified risk tobacco product; Mutagenicity; THS2.2; Tobacco heating system

Indexed keywords

CARBON MONOXIDE; HARMFUL AND POTENTIALLY HARMFUL CONSTITUENT; NITROGEN OXIDE; TOXIC SUBSTANCE; UNCLASSIFIED DRUG; AEROSOL; SMOKE;

AEROSOL; ANALYTICAL PARAMETERS; ANIMAL CELL; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; CHEMICAL MODIFICATION; CHEMICAL REACTION; CONTROLLED STUDY; CYTOTOXICITY; EVALUATION STUDY; FLAME IONIZATION DETECTION; GAS CHROMATOGRAPHY; GENERAL DEVICE; GENOTOXICITY; HUMIDITY; IN VITRO STUDY; LIMIT OF QUANTITATION; MACHINE SMOKING; MALE; MASS MEDIAN AERODYNAMIC DIAMETER; MOUSE; MUTAGENICITY; MUTATION RATE; NONHUMAN; OBSERVATIONAL STUDY; PARTICULATE MATTER; PRIORITY JOURNAL; RAT; SEASONAL VARIATION; SMOKING; TEMPERATURE; TOBACCO HEATING SYSTEM; TOBACCO PLUG; 3T3 CELL LINE; ADVERSE EFFECTS; ANALYSIS; ANIMAL; BIOLOGY; CELL SURVIVAL; COMPARATIVE STUDY; DRUG EFFECTS; ELECTRONIC CIGARETTE; EQUIPMENT DESIGN; EXPOSURE; GENETICS; GENOMICS; HARM REDUCTION; HEAT; HUMAN; MUTAGEN TESTING; MUTAGENESIS; PARTICLE SIZE; PROCEDURES; PRODUCT SAFETY; RISK ASSESSMENT; SMOKE; TOBACCO; TOBACCO INDUSTRY; TOXICITY;

AEROSOLS; ANIMALS; BALB 3T3 CELLS; CELL SURVIVAL; COMPUTATIONAL BIOLOGY; CONSUMER PRODUCT SAFETY; ELECTRONIC CIGARETTES; EQUIPMENT DESIGN; GENOMICS; HARM REDUCTION; HOT TEMPERATURE; HUMANS; INHALATION EXPOSURE; MICE; MUTAGENESIS; MUTAGENICITY TESTS; PARTICLE SIZE; RISK ASSESSMENT; SMOKE; SMOKING; TOBACCO INDUSTRY; TOBACCO PRODUCTS;

EID: 85006942693     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2016.10.001     Document Type: Article

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