Evaluation of the tobacco heating system 2.2. Part 9: Application of systems pharmacology to identify exposure response markers in peripheral blood of smokers switching to THS2.2

Regulatory Toxicology and Pharmacology

Volumn 81, Issue , 2016, Pages S151-S157

  Martin, Florian ^a   Talikka, Marja ^a   Ivanov, Nikolai V ^a   Haziza, Christelle ^a   Hoeng, Julia ^a   Peitsch, Manuel C ^a  

^a Philip Morris Products SA   (Switzerland)

Author keywords

Blood; Exposure response; Gene expression signature; MRTP; Novel tobacco heating system; Smoking

Indexed keywords

BIOLOGICAL MARKER; MENTHOL; TRANSCRIPTOME; AEROSOL; GENETIC MARKER; SMOKE;

ARTICLE; CHEMICAL COMPOSITION; CONTROLLED STUDY; GENE IDENTIFICATION; HEALTH HAZARD; HEATING; HUMAN; MARKER GENE; MEASUREMENT; OPEN STUDY; PARALLEL DESIGN; PHARMACOLOGY; POPULATION RESEARCH; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; RISK REDUCTION; SENSITIVITY AND SPECIFICITY; SMOKING; SMOKING CESSATION; ADVERSE EFFECTS; AEROSOL; BLOOD; COMPARATIVE STUDY; DRUG EFFECTS; ELECTRONIC CIGARETTE; EQUIPMENT DESIGN; EXPOSURE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC MARKER; GENETICS; GENOMICS; HARM REDUCTION; HEAT; POLAND; PREVENTION AND CONTROL; PROCEDURES; PRODUCT SAFETY; RISK ASSESSMENT; SMOKE; SYSTEMS BIOLOGY; TOBACCO; TOBACCO INDUSTRY; TOXICITY; TOXICITY TESTING;

AEROSOLS; BIOMARKERS; CONSUMER PRODUCT SAFETY; ELECTRONIC CIGARETTES; EQUIPMENT DESIGN; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC MARKERS; GENOMICS; HARM REDUCTION; HOT TEMPERATURE; HUMANS; INHALATION EXPOSURE; POLAND; RISK ASSESSMENT; SMOKE; SMOKING; SMOKING CESSATION; SYSTEMS BIOLOGY; TOBACCO INDUSTRY; TOBACCO PRODUCTS; TOXICITY TESTS; TRANSCRIPTOME;

EID: 85006802531     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2016.11.011     Document Type: Article

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