-
1
-
-
84855645313
-
Mechanisms of autophagosome biogenesis
-
Rubinsztein DC, Shpilka T, Elazar Z. Mechanisms of autophagosome biogenesis. Curr Biol (2012) 22:R29. doi:10.1016/j.cub.2011.11.034
-
(2012)
Curr Biol
, vol.22
, pp. R29
-
-
Rubinsztein, D.C.1
Shpilka, T.2
Elazar, Z.3
-
3
-
-
0024375860
-
The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein
-
McGrath JP, Varshavsky A. The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein. Nature (1989) 340:400. doi:10.1038/340400a0
-
(1989)
Nature
, vol.340
, pp. 400
-
-
McGrath, J.P.1
Varshavsky, A.2
-
4
-
-
74949118681
-
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
-
Rouschop KM, van den Beucken T, Dubois L, Niessen H, Bussink J, Savelkouls K, et al. The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. J Clin Invest (2010) 120:127. doi:10.1172/JCI40027
-
(2010)
J Clin Invest
, vol.120
, pp. 127
-
-
Rouschop, K.M.1
van den Beucken, T.2
Dubois, L.3
Niessen, H.4
Bussink, J.5
Savelkouls, K.6
-
6
-
-
0036359548
-
Hypoxia-a key regulatory factor in tumour growth
-
Harris AL. Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer (2002) 2:38. doi:10.1038/nrc704
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38
-
-
Harris, A.L.1
-
7
-
-
8444242974
-
Bi-directional protein transport between the ER and Golgi
-
Lee MC, Miller EA, Goldberg J, Orci L, Schekman R. Bi-directional protein transport between the ER and Golgi. Annu Rev Cell Dev Biol (2004) 20:87. doi:10.1146/annurev.cellbio.20.010403.105307
-
(2004)
Annu Rev Cell Dev Biol
, vol.20
, pp. 87
-
-
Lee, M.C.1
Miller, E.A.2
Goldberg, J.3
Orci, L.4
Schekman, R.5
-
8
-
-
0038603127
-
Constitutive protein secretion from the trans-Golgi network to the plasma membrane
-
Ponnambalam S, Baldwin SA. Constitutive protein secretion from the trans-Golgi network to the plasma membrane. Mol Membr Biol (2003) 20:129. doi:10.1080/0968768031000084172
-
(2003)
Mol Membr Biol
, vol.20
, pp. 129
-
-
Ponnambalam, S.1
Baldwin, S.A.2
-
9
-
-
84873531806
-
Diversity in unconventional protein secretion
-
Rabouille C, Malhotra V, Nickel W. Diversity in unconventional protein secretion. J Cell Sci (2012) 125:5251. doi:10.1242/jcs.103630
-
(2012)
J Cell Sci
, vol.125
, pp. 5251
-
-
Rabouille, C.1
Malhotra, V.2
Nickel, W.3
-
10
-
-
84864980066
-
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2)-dependent oligomerization of fibroblast growth factor 2 (FGF2) triggers the formation of a lipidic membrane pore implicated in unconventional secretion
-
Steringer JP, Bleicken S, Andreas H, Zacherl S, Laussmann M, Temmerman K, et al. Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2)-dependent oligomerization of fibroblast growth factor 2 (FGF2) triggers the formation of a lipidic membrane pore implicated in unconventional secretion. J Biol Chem (2012) 287:27659. doi:10.1074/jbc.M112.381939
-
(2012)
J Biol Chem
, vol.287
, pp. 27659
-
-
Steringer, J.P.1
Bleicken, S.2
Andreas, H.3
Zacherl, S.4
Laussmann, M.5
Temmerman, K.6
-
11
-
-
82455210868
-
Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1beta
-
Dupont N, Jiang S, Pilli M, Ornatowski W, Bhattacharya D, Deretic V. Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1beta. EMBO J (2011) 30:4701. doi:10.1038/emboj.2011.398
-
(2011)
EMBO J
, vol.30
, pp. 4701
-
-
Dupont, N.1
Jiang, S.2
Pilli, M.3
Ornatowski, W.4
Bhattacharya, D.5
Deretic, V.6
-
12
-
-
84875891875
-
A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells
-
Pallet N, Sirois I, Bell C, Hanafi LA, Hamelin K, Dieudé M, et al. A comprehensive characterization of membrane vesicles released by autophagic human endothelial cells. Proteomics (2013) 13:1108. doi:10.1002/pmic.201200531
-
(2013)
Proteomics
, vol.13
, pp. 1108
-
-
Pallet, N.1
Sirois, I.2
Bell, C.3
Hanafi, L.A.4
Hamelin, K.5
Dieudé, M.6
-
13
-
-
84864885614
-
Caspase activation regulates the extracellular export of autophagic vacuoles
-
Sirois I, Groleau J, Pallet N, Brassard N, Hamelin K, Londono I, et al. Caspase activation regulates the extracellular export of autophagic vacuoles. Autophagy (2012) 8:927. doi:10.4161/auto.19768
-
(2012)
Autophagy
, vol.8
, pp. 927
-
-
Sirois, I.1
Groleau, J.2
Pallet, N.3
Brassard, N.4
Hamelin, K.5
Londono, I.6
-
14
-
-
84938693671
-
Secretory autophagy
-
Ponpuak M, Mandell MA, Kimura T, Chauhan S, Cleyrat C, Deretic V. Secretory autophagy. Curr Opin Cell Biol (2015) 35:106. doi:10.1016/j.ceb.2015.04.016
-
(2015)
Curr Opin Cell Biol
, vol.35
, pp. 106
-
-
Ponpuak, M.1
Mandell, M.A.2
Kimura, T.3
Chauhan, S.4
Cleyrat, C.5
Deretic, V.6
-
15
-
-
57649195400
-
Autophagy and multivesicular bodies: two closely related partners
-
Fader CM, Colombo MI. Autophagy and multivesicular bodies: two closely related partners. Cell Death Differ (2009) 16:70. doi:10.1038/cdd.2008.168
-
(2009)
Cell Death Differ
, vol.16
, pp. 70
-
-
Fader, C.M.1
Colombo, M.I.2
-
16
-
-
77149155386
-
Unconventional secretion of Acb1 is mediated by autophagosomes
-
Duran JM, Anjard C, Stefan C, Loomis WF, Malhotra V. Unconventional secretion of Acb1 is mediated by autophagosomes. J Cell Biol (2010) 188:527. doi:10.1083/jcb.200911154
-
(2010)
J Cell Biol
, vol.188
, pp. 527
-
-
Duran, J.M.1
Anjard, C.2
Stefan, C.3
Loomis, W.F.4
Malhotra, V.5
-
17
-
-
84976272267
-
The roles of phosphoinositides in mammalian autophagy
-
Jang DJ, Lee JA. The roles of phosphoinositides in mammalian autophagy. Arch Pharm Res (2016) 39:1129. doi:10.1007/s12272-016-0777-x
-
(2016)
Arch Pharm Res
, vol.39
, pp. 1129
-
-
Jang, D.J.1
Lee, J.A.2
-
18
-
-
77950506156
-
Regulation of autophagy by phosphatidylinositol 3-phosphate
-
Burman C, Ktistakis NT. Regulation of autophagy by phosphatidylinositol 3-phosphate. FEBS Lett (2010) 584:1302. doi:10.1016/j.febslet.2010.01.011
-
(2010)
FEBS Lett
, vol.584
, pp. 1302
-
-
Burman, C.1
Ktistakis, N.T.2
-
19
-
-
84979243223
-
PIKfyve inhibition increases exosome release and induces secretory autophagy
-
Hessvik NP, Øverbye A, Brech A, Torgersen ML, Jakobsen IS, Sandvig K, et al. PIKfyve inhibition increases exosome release and induces secretory autophagy. Cell Mol Life Sci (2016). doi:10.1007/s00018-016-2309-8
-
(2016)
Cell Mol Life Sci
-
-
Hessvik, N.P.1
Øverbye, A.2
Brech, A.3
Torgersen, M.L.4
Jakobsen, I.S.5
Sandvig, K.6
-
20
-
-
84875445306
-
Gene deletion of Gabarap enhances Nlrp3 inflammasome-dependent inflammatory responses
-
Zhang Z, Xu X, Ma J, Wu J, Wang Y, Zhou R, et al. Gene deletion of Gabarap enhances Nlrp3 inflammasome-dependent inflammatory responses. J Immunol (2013) 190:3517. doi:10.4049/jimmunol.1202628
-
(2013)
J Immunol
, vol.190
, pp. 3517
-
-
Zhang, Z.1
Xu, X.2
Ma, J.3
Wu, J.4
Wang, Y.5
Zhou, R.6
-
21
-
-
84955292894
-
Translocation of interleukin-1beta into a vesicle intermediate in autophagy-mediated secretion
-
Zhang M, Kenny SJ, Ge L, Xu K, Schekman R. Translocation of interleukin-1beta into a vesicle intermediate in autophagy-mediated secretion. Elife (2015) 4. doi:10.7554/eLife.11205
-
(2015)
Elife
, vol.4
-
-
Zhang, M.1
Kenny, S.J.2
Ge, L.3
Xu, K.4
Schekman, R.5
-
22
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
-
Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK, et al. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature (2008) 456:259. doi:10.1038/nature07416
-
(2008)
Nature
, vol.456
, pp. 259
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
Miyoshi, H.4
Loh, J.5
Lennerz, J.K.6
-
23
-
-
61649114427
-
A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease
-
Cadwell K, Patel KK, Komatsu M, Virgin HW IV, Stappenbeck TS. A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease. Autophagy (2009) 5:250. doi:10.4161/auto.5.2.7560
-
(2009)
Autophagy
, vol.5
, pp. 250
-
-
Cadwell, K.1
Patel, K.K.2
Komatsu, M.3
Virgin, H.W.4
Stappenbeck, T.S.5
-
24
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe J, Franke A, Rosenstiel P, Till A, Teuber M, Huse K, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet (2007) 39:207. doi:10.1038/ng1954
-
(2007)
Nat Genet
, vol.39
, pp. 207
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
Till, A.4
Teuber, M.5
Huse, K.6
-
25
-
-
84939634792
-
Autophagy protects against colitis by the maintenance of normal gut microflora and secretion of mucus
-
Tsuboi K, Nishitani M, Takakura A, Imai Y, Komatsu M, Kawashima H. Autophagy protects against colitis by the maintenance of normal gut microflora and secretion of mucus. J Biol Chem (2015) 290:20511. doi:10.1074/jbc.M114.632257
-
(2015)
J Biol Chem
, vol.290
, pp. 20511
-
-
Tsuboi, K.1
Nishitani, M.2
Takakura, A.3
Imai, Y.4
Komatsu, M.5
Kawashima, H.6
-
26
-
-
84964523667
-
IL13 activates autophagy to regulate secretion in airway epithelial cells
-
Dickinson JD, Alevy Y, Malvin NP, Patel KK, Gunsten SP, Holtzman MJ, et al. IL13 activates autophagy to regulate secretion in airway epithelial cells. Autophagy (2016) 12:397. doi:10.1080/15548627.2015.1056967
-
(2016)
Autophagy
, vol.12
, pp. 397
-
-
Dickinson, J.D.1
Alevy, Y.2
Malvin, N.P.3
Patel, K.K.4
Gunsten, S.P.5
Holtzman, M.J.6
-
27
-
-
84888223618
-
Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection
-
Conway KL, Kuballa P, Song JH, Patel KK, Castoreno AB, Yilmaz OH, et al. Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection. Gastroenterology (2013) 145:1347. doi:10.1053/j.gastro.2013.08.035
-
(2013)
Gastroenterology
, vol.145
, pp. 1347
-
-
Conway, K.L.1
Kuballa, P.2
Song, J.H.3
Patel, K.K.4
Castoreno, A.B.5
Yilmaz, O.H.6
-
28
-
-
84869080400
-
LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy
-
von Muhlinen N, Akutsu M, Ravenhill BJ, Foeglein Á, Bloor S, Rutherford TJ, et al. LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy. Mol Cell (2012) 48:329. doi:10.1016/j.molcel.2012.08.024
-
(2012)
Mol Cell
, vol.48
, pp. 329
-
-
von Muhlinen, N.1
Akutsu, M.2
Ravenhill, B.J.3
Foeglein, Á.4
Bloor, S.5
Rutherford, T.J.6
-
29
-
-
77953122645
-
LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis
-
Weidberg H, Shvets E, Shpilka T, Shimron F, Shinder V, Elazar Z. LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis. EMBO J (2010) 29:1792. doi:10.1038/emboj.2010.74
-
(2010)
EMBO J
, vol.29
, pp. 1792
-
-
Weidberg, H.1
Shvets, E.2
Shpilka, T.3
Shimron, F.4
Shinder, V.5
Elazar, Z.6
-
30
-
-
0037012104
-
Structure of GABARAP in two conformations: implications for GABA(A) receptor localization and tubulin binding
-
Coyle JE, Qamar S, Rajashankar KR, Nikolov DB. Structure of GABARAP in two conformations: implications for GABA(A) receptor localization and tubulin binding. Neuron (2002) 33:63. doi:10.1016/S0896-6273(01)00558-X
-
(2002)
Neuron
, vol.33
, pp. 63
-
-
Coyle, J.E.1
Qamar, S.2
Rajashankar, K.R.3
Nikolov, D.B.4
-
31
-
-
84899844485
-
Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3
-
Nath S, Dancourt J, Shteyn V, Puente G, Fong WM, Nag S, et al. Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3. Nat Cell Biol (2014) 16:415. doi:10.1038/ncb2940
-
(2014)
Nat Cell Biol
, vol.16
, pp. 415
-
-
Nath, S.1
Dancourt, J.2
Shteyn, V.3
Puente, G.4
Fong, W.M.5
Nag, S.6
-
32
-
-
84979036957
-
Phospholipase C-related catalytically inactive protein (PRIP) controls KIF5B-mediated insulin secretion
-
Asano S, Nemoto T, Kitayama T, Harada K, Zhang J, Harada K, et al. Phospholipase C-related catalytically inactive protein (PRIP) controls KIF5B-mediated insulin secretion. Biol Open (2014) 3:463. doi:10.1242/bio.20147591
-
(2014)
Biol Open
, vol.3
, pp. 463
-
-
Asano, S.1
Nemoto, T.2
Kitayama, T.3
Harada, K.4
Zhang, J.5
Harada, K.6
-
33
-
-
84871888497
-
Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity
-
Ishibashi K, Uemura T, Waguri S, Fukuda M. Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity. Mol Biol Cell (2012) 23:3193. doi:10.1091/mbc.E12-01-0010
-
(2012)
Mol Biol Cell
, vol.23
, pp. 3193
-
-
Ishibashi, K.1
Uemura, T.2
Waguri, S.3
Fukuda, M.4
-
34
-
-
84887489438
-
Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor
-
Torisu T, Torisu K, Lee IH, Liu J, Malide D, Combs CA, et al. Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor. Nat Med (2013) 19:1281. doi:10.1038/nm.3288
-
(2013)
Nat Med
, vol.19
, pp. 1281
-
-
Torisu, T.1
Torisu, K.2
Lee, I.H.3
Liu, J.4
Malide, D.5
Combs, C.A.6
-
35
-
-
80755175726
-
Autophagy proteins regulate the secretory component of osteoclastic bone resorption
-
DeSelm CJ, Miller BC, Zou W, Beatty WL, van Meel E, Takahata Y, et al. Autophagy proteins regulate the secretory component of osteoclastic bone resorption. Dev Cell (2011) 21:966. doi:10.1016/j.devcel.2011.08.016
-
(2011)
Dev Cell
, vol.21
, pp. 966
-
-
DeSelm, C.J.1
Miller, B.C.2
Zou, W.3
Beatty, W.L.4
van Meel, E.5
Takahata, Y.6
-
36
-
-
53049098471
-
Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells
-
Vogiatzi T, Xilouri M, Vekrellis K, Stefanis L. Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells. J Biol Chem (2008) 283:23542. doi:10.1074/jbc.M801992200
-
(2008)
J Biol Chem
, vol.283
, pp. 23542
-
-
Vogiatzi, T.1
Xilouri, M.2
Vekrellis, K.3
Stefanis, L.4
-
37
-
-
84879052241
-
Tubulin polymerization-promoting protein (TPPP/p25a) promotes unconventional secretion of a-synuclein through exophagy by impairing autophagosome-lysosome fusion
-
Ejlerskov P, Rasmussen I, Nielsen TT, Bergström AL, Tohyama Y, Jensen PH, et al. Tubulin polymerization-promoting protein (TPPP/p25a) promotes unconventional secretion of a-synuclein through exophagy by impairing autophagosome-lysosome fusion. J Biol Chem (2013) 288:17313. doi:10.1074/jbc.M112.401174
-
(2013)
J Biol Chem
, vol.288
, pp. 17313
-
-
Ejlerskov, P.1
Rasmussen, I.2
Nielsen, T.T.3
Bergström, A.L.4
Tohyama, Y.5
Jensen, P.H.6
-
38
-
-
84885864424
-
Aß secretion and plaque formation depend on autophagy
-
Nilsson P, Loganathan K, Sekiguchi M, Matsuba Y, Hui K, Tsubuki S, et al. Aß secretion and plaque formation depend on autophagy. Cell Rep (2013) 5:61. doi:10.1016/j.celrep.2013.08.042
-
(2013)
Cell Rep
, vol.5
, pp. 61
-
-
Nilsson, P.1
Loganathan, K.2
Sekiguchi, M.3
Matsuba, Y.4
Hui, K.5
Tsubuki, S.6
-
39
-
-
85060496113
-
Mitochondrial reactive oxygen species and cancer
-
Sullivan LB, Chandel NS. Mitochondrial reactive oxygen species and cancer. Cancer Metab (2014) 2:17. doi:10.1186/2049-3002-2-17
-
(2014)
Cancer Metab
, vol.2
, pp. 17
-
-
Sullivan, L.B.1
Chandel, N.S.2
-
40
-
-
84943795327
-
Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs
-
Phinney DG, Di Giuseppe M, Njah J, Sala E, Shiva S, St Croix CM, et al. Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs. Nat Commun (2015) 6:8472. doi:10.1038/ncomms9472
-
(2015)
Nat Commun
, vol.6
, pp. 8472
-
-
Phinney, D.G.1
Di Giuseppe, M.2
Njah, J.3
Sala, E.4
Shiva, S.5
St Croix, C.M.6
-
41
-
-
84953864679
-
Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: involvement of autophagy
-
Unuma K, Aki T, Funakoshi T, Hashimoto K, Uemura K. Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: involvement of autophagy. Autophagy (2015) 11:1520. doi:10.1080/15548627.2015.1063765
-
(2015)
Autophagy
, vol.11
, pp. 1520
-
-
Unuma, K.1
Aki, T.2
Funakoshi, T.3
Hashimoto, K.4
Uemura, K.5
-
42
-
-
44349157832
-
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
-
Dewhirst MW, Cao Y, Moeller B. Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response. Nat Rev Cancer (2008) 8:425. doi:10.1038/nrc2397
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 425
-
-
Dewhirst, M.W.1
Cao, Y.2
Moeller, B.3
-
43
-
-
26444466467
-
Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study
-
Nordsmark M, Bentzen SM, Rudat V, Brizel D, Lartigau E, Stadler P, et al. Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study. Radiother Oncol (2005) 77:18. doi:10.1016/j.radonc.2005.06.038
-
(2005)
Radiother Oncol
, vol.77
, pp. 18
-
-
Nordsmark, M.1
Bentzen, S.M.2
Rudat, V.3
Brizel, D.4
Lartigau, E.5
Stadler, P.6
-
44
-
-
35348886043
-
Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein
-
Cao Y, Klionsky DJ. Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein. Cell Res (2007) 17:839. doi:10.1038/cr.2007.78
-
(2007)
Cell Res
, vol.17
, pp. 839
-
-
Cao, Y.1
Klionsky, D.J.2
-
45
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
Qu X, Yu J, Bhagat G, Furuya N, Hibshoosh H, Troxel A, et al. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest (2003) 112:1809. doi:10.1172/JCI20039
-
(2003)
J Clin Invest
, vol.112
, pp. 1809
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
Furuya, N.4
Hibshoosh, H.5
Troxel, A.6
-
46
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
Yue Z, Jin S, Yang C, Levine AJ, Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A (2003) 100:15077. doi:10.1073/pnas.2436255100
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15077
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
47
-
-
79960401862
-
Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis
-
Wei H, Wei S, Gan B, Peng X, Zou W, Guan JL. Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis. Genes Dev (2011) 25:1510. doi:10.1101/gad.2051011
-
(2011)
Genes Dev
, vol.25
, pp. 1510
-
-
Wei, H.1
Wei, S.2
Gan, B.3
Peng, X.4
Zou, W.5
Guan, J.L.6
-
48
-
-
69949112039
-
Autophagy is required during cycling hypoxia to lower production of reactive oxygen species
-
Rouschop KM, Ramaekers CH, Schaaf MB, Keulers TG, Savelkouls KG, Lambin P, et al. Autophagy is required during cycling hypoxia to lower production of reactive oxygen species. Radiother Oncol (2009) 92:411. doi:10.1016/j.radonc.2009.06.029
-
(2009)
Radiother Oncol
, vol.92
, pp. 411
-
-
Rouschop, K.M.1
Ramaekers, C.H.2
Schaaf, M.B.3
Keulers, T.G.4
Savelkouls, K.G.5
Lambin, P.6
-
49
-
-
84887018838
-
The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia
-
Schaaf MB, Cojocari D, Keulers TG, Jutten B, Starmans MH, de Jong MC, et al. The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia. Radiother Oncol (2013) 108:529. doi:10.1016/j.radonc.2013.06.015
-
(2013)
Radiother Oncol
, vol.108
, pp. 529
-
-
Schaaf, M.B.1
Cojocari, D.2
Keulers, T.G.3
Jutten, B.4
Starmans, M.H.5
de Jong, M.C.6
-
50
-
-
84871429513
-
Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival
-
Pike LR, Singleton DC, Buffa F, Abramczyk O, Phadwal K, Li JL, et al. Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival. Biochem J (2013) 449:389. doi:10.1042/BJ20120972
-
(2013)
Biochem J
, vol.449
, pp. 389
-
-
Pike, L.R.1
Singleton, D.C.2
Buffa, F.3
Abramczyk, O.4
Phadwal, K.5
Li, J.L.6
-
51
-
-
84944167107
-
GABARAPL1 is required for increased EGFR membrane expression during hypoxia
-
Keulers TG, Schaaf MB, Peeters HJ, Savelkouls KG, Vooijs MA, Bussink J, et al. GABARAPL1 is required for increased EGFR membrane expression during hypoxia. Radiother Oncol (2015) 116:417. doi:10.1016/j.radonc.2015.06.023
-
(2015)
Radiother Oncol
, vol.116
, pp. 417
-
-
Keulers, T.G.1
Schaaf, M.B.2
Peeters, H.J.3
Savelkouls, K.G.4
Vooijs, M.A.5
Bussink, J.6
-
52
-
-
84887023636
-
EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival
-
Jutten B, Keulers TG, Schaaf MB, Savelkouls K, Theys J, Span PN, et al. EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival. Radiother Oncol (2013) 108:479. doi:10.1016/j.radonc.2013.06.033
-
(2013)
Radiother Oncol
, vol.108
, pp. 479
-
-
Jutten, B.1
Keulers, T.G.2
Schaaf, M.B.3
Savelkouls, K.4
Theys, J.5
Span, P.N.6
-
53
-
-
84953274881
-
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
-
Eng CH, Wang Z, Tkach D, Toral-Barza L, Ugwonali S, Liu S, et al. Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy. Proc Natl Acad Sci U S A (2016) 113:182. doi:10.1073/pnas.1515617113
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. 182
-
-
Eng, C.H.1
Wang, Z.2
Tkach, D.3
Toral-Barza, L.4
Ugwonali, S.5
Liu, S.6
-
54
-
-
79952228407
-
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
-
Guo JY, Chen HY, Mathew R, Fan J, Strohecker AM, Karsli-Uzunbas G, et al. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev (2011) 25:460. doi:10.1101/gad.2016311
-
(2011)
Genes Dev
, vol.25
, pp. 460
-
-
Guo, J.Y.1
Chen, H.Y.2
Mathew, R.3
Fan, J.4
Strohecker, A.M.5
Karsli-Uzunbas, G.6
-
55
-
-
84897946801
-
Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion
-
Lock R, Kenific CM, Leidal AM, Salas E, Debnath J. Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion. Cancer Discov (2014) 4:466. doi:10.1158/2159-8290.CD-13-0841
-
(2014)
Cancer Discov
, vol.4
, pp. 466
-
-
Lock, R.1
Kenific, C.M.2
Leidal, A.M.3
Salas, E.4
Debnath, J.5
-
56
-
-
84949681065
-
Molecular and translational classifications of DAMPs in immunogenic cell death
-
Garg AD, Galluzzi L, Apetoh L, Baert T, Birge RB, Bravo-San Pedro JM, et al. Molecular and translational classifications of DAMPs in immunogenic cell death. Front Immunol (2015) 6:588. doi:10.3389/fimmu.2015.00588
-
(2015)
Front Immunol
, vol.6
, pp. 588
-
-
Garg, A.D.1
Galluzzi, L.2
Apetoh, L.3
Baert, T.4
Birge, R.B.5
Bravo-San Pedro, J.M.6
-
57
-
-
75349083568
-
Immunogenic cell death, DAMPs and anticancer therapeutics: an emerging amalgamation
-
Garg AD, Nowis D, Golab J, Vandenabeele P, Krysko DV, Agostinis P. Immunogenic cell death, DAMPs and anticancer therapeutics: an emerging amalgamation. Biochim Biophys Acta (2010) 1805:53. doi:10.1016/j.bbcan.2009.08.003
-
(2010)
Biochim Biophys Acta
, vol.1805
, pp. 53
-
-
Garg, A.D.1
Nowis, D.2
Golab, J.3
Vandenabeele, P.4
Krysko, D.V.5
Agostinis, P.6
-
58
-
-
67650481213
-
Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas
-
Ray-Coquard I, Cropet C, Van Glabbeke M, Sebban C, Le Cesne A, Judson I, et al. Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas. Cancer Res (2009) 69:5383. doi:10.1158/0008-5472.CAN-08-3845
-
(2009)
Cancer Res
, vol.69
, pp. 5383
-
-
Ray-Coquard, I.1
Cropet, C.2
Van Glabbeke, M.3
Sebban, C.4
Le Cesne, A.5
Judson, I.6
-
59
-
-
84959387168
-
Immunological metagene signatures derived from immunogenic cancer cell death associate with improved survival of patients with lung, breast or ovarian malignancies: a large-scale meta-analysis
-
Garg AD, De Ruysscher D, Agostinis P. Immunological metagene signatures derived from immunogenic cancer cell death associate with improved survival of patients with lung, breast or ovarian malignancies: a large-scale meta-analysis. Oncoimmunology (2016) 5:e1069938. doi:10.1080/2162402X.2015.1069938
-
(2016)
Oncoimmunology
, vol.5
-
-
Garg, A.D.1
De Ruysscher, D.2
Agostinis, P.3
-
60
-
-
84890032905
-
Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling
-
Ko A, Kanehisa A, Martins I, Senovilla L, Chargari C, Dugue D, et al. Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling. Cell Death Differ (2014) 21:92. doi:10.1038/cdd.2013.124
-
(2014)
Cell Death Differ
, vol.21
, pp. 92
-
-
Ko, A.1
Kanehisa, A.2
Martins, I.3
Senovilla, L.4
Chargari, C.5
Dugue, D.6
-
61
-
-
83755181759
-
Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice
-
Michaud M, Martins I, Sukkurwala AQ, Adjemian S, Ma Y, Pellegatti P, et al. Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice. Science (2011) 334:1573. doi:10.1126/science.1208347
-
(2011)
Science
, vol.334
, pp. 1573
-
-
Michaud, M.1
Martins, I.2
Sukkurwala, A.Q.3
Adjemian, S.4
Ma, Y.5
Pellegatti, P.6
-
62
-
-
84890103572
-
Molecular mechanisms of ATP secretion during immunogenic cell death
-
Martins I, Wang Y, Michaud M, Ma Y, Sukkurwala AQ, Shen S, et al. Molecular mechanisms of ATP secretion during immunogenic cell death. Cell Death Differ (2014) 21:79. doi:10.1038/cdd.2013.75
-
(2014)
Cell Death Differ
, vol.21
, pp. 79
-
-
Martins, I.1
Wang, Y.2
Michaud, M.3
Ma, Y.4
Sukkurwala, A.Q.5
Shen, S.6
-
63
-
-
84911453574
-
An autophagy-dependent anticancer immune response determines the efficacy of melanoma chemotherapy
-
Michaud M, Xie X, Bravo-San Pedro JM, Zitvogel L, White E, Kroemer G. An autophagy-dependent anticancer immune response determines the efficacy of melanoma chemotherapy. Oncoimmunology (2014) 3:e944047. doi:10.4161/21624011.2014.944047
-
(2014)
Oncoimmunology
, vol.3
-
-
Michaud, M.1
Xie, X.2
Bravo-San Pedro, J.M.3
Zitvogel, L.4
White, E.5
Kroemer, G.6
-
64
-
-
84979780741
-
Caloric restriction mimetics enhance anticancer immunosurveillance
-
Pietrocola F, Pol J, Vacchelli E, Rao S, Enot DP, Baracco EE, et al. Caloric restriction mimetics enhance anticancer immunosurveillance. Cancer cell (2016) 30:147. doi:10.1016/j.ccell.2016.05.016
-
(2016)
Cancer cell
, vol.30
, pp. 147
-
-
Pietrocola, F.1
Pol, J.2
Vacchelli, E.3
Rao, S.4
Enot, D.P.5
Baracco, E.E.6
-
65
-
-
84879783969
-
ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death
-
Garg AD, Dudek AM, Ferreira GB, Verfaillie T, Vandenabeele P, Krysko DV, et al. ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death. Autophagy (2013) 9:1292. doi:10.4161/auto.25399
-
(2013)
Autophagy
, vol.9
, pp. 1292
-
-
Garg, A.D.1
Dudek, A.M.2
Ferreira, G.B.3
Verfaillie, T.4
Vandenabeele, P.5
Krysko, D.V.6
-
66
-
-
84887445500
-
Calreticulin surface exposure is abrogated in cells lacking, chaperone-mediated autophagy-essential gene, LAMP2A
-
Garg AD, Dudek AM, Agostinis P. Calreticulin surface exposure is abrogated in cells lacking, chaperone-mediated autophagy-essential gene, LAMP2A. Cell Death Dis (2013) 4:e826. doi:10.1038/cddis.2013.372
-
(2013)
Cell Death Dis
, vol.4
-
-
Garg, A.D.1
Dudek, A.M.2
Agostinis, P.3
-
67
-
-
84974784979
-
Extracellular ATP and P(2)X(7) receptor exert context-specific immunogenic effects after immunogenic cancer cell death
-
Garg AD, Krysko DV, Vandenabeele P, Agostinis P. Extracellular ATP and P(2)X(7) receptor exert context-specific immunogenic effects after immunogenic cancer cell death. Cell Death Dis (2016) 7:e2097. doi:10.1038/cddis.2015.411
-
(2016)
Cell Death Dis
, vol.7
-
-
Garg, A.D.1
Krysko, D.V.2
Vandenabeele, P.3
Agostinis, P.4
-
68
-
-
57649217868
-
Autophagy regulates selective HMGB1 release in tumor cells that are destined to die
-
Thorburn J, Horita H, Redzic J, Hansen K, Frankel AE, Thorburn A. Autophagy regulates selective HMGB1 release in tumor cells that are destined to die. Cell Death Differ (2009) 16:175. doi:10.1038/cdd.2008.143
-
(2009)
Cell Death Differ
, vol.16
, pp. 175
-
-
Thorburn, J.1
Horita, H.2
Redzic, J.3
Hansen, K.4
Frankel, A.E.5
Thorburn, A.6
-
69
-
-
35748942876
-
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy
-
Apetoh L, Ghiringhelli F, Tesniere A, Criollo A, Ortiz C, Lidereau R, et al. The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy. Immunol Rev (2007) 220:47. doi:10.1111/j.1600-065X.2007.00573.x
-
(2007)
Immunol Rev
, vol.220
, pp. 47
-
-
Apetoh, L.1
Ghiringhelli, F.2
Tesniere, A.3
Criollo, A.4
Ortiz, C.5
Lidereau, R.6
-
70
-
-
83955162908
-
High mobility group box 1 promotes endothelial cell angiogenic behavior in vitro and improves muscle perfusion in vivo in response to ischemic injury
-
Sachdev U, Cui X, Hong G, Namkoong S, Karlsson JM, Baty CJ, et al. High mobility group box 1 promotes endothelial cell angiogenic behavior in vitro and improves muscle perfusion in vivo in response to ischemic injury. J Vasc Surg (2012) 55:180. doi:10.1016/j.jvs.2011.07.072
-
(2012)
J Vasc Surg
, vol.55
, pp. 180
-
-
Sachdev, U.1
Cui, X.2
Hong, G.3
Namkoong, S.4
Karlsson, J.M.5
Baty, C.J.6
-
71
-
-
84872615463
-
Tumor angiogenesis is enforced by autocrine regulation of high-mobility group box 1
-
van Beijnum JR, Nowak-Sliwinska P, van den Boezem E, Hautvast P, Buurman WA, Griffioen AW. Tumor angiogenesis is enforced by autocrine regulation of high-mobility group box 1. Oncogene (2013) 32:363. doi:10.1038/onc.2012.49
-
(2013)
Oncogene
, vol.32
, pp. 363
-
-
van Beijnum, J.R.1
Nowak-Sliwinska, P.2
van den Boezem, E.3
Hautvast, P.4
Buurman, W.A.5
Griffioen, A.W.6
-
72
-
-
84957729045
-
Vesicular trafficking mechanisms in endothelial cells as modulators of the tumor vasculature and targets of antiangiogenic therapies
-
Maes H, Olmeda D, Soengas MS, Agostinis P. Vesicular trafficking mechanisms in endothelial cells as modulators of the tumor vasculature and targets of antiangiogenic therapies. FEBS J (2016) 283:25. doi:10.1111/febs.13545
-
(2016)
FEBS J
, vol.283
, pp. 25
-
-
Maes, H.1
Olmeda, D.2
Soengas, M.S.3
Agostinis, P.4
-
73
-
-
84959452716
-
Dendritic cell vaccines based on immunogenic cell death elicit danger signals and T cell-driven rejection of high-grade glioma
-
Garg AD, Vandenberk L, Koks C, Verschuere T, Boon L, Van Gool SW, et al. Dendritic cell vaccines based on immunogenic cell death elicit danger signals and T cell-driven rejection of high-grade glioma. Sci Transl Med (2016) 8:328ra27. doi:10.1126/scitranslmed.aae0105
-
(2016)
Sci Transl Med
, vol.8
-
-
Garg, A.D.1
Vandenberk, L.2
Koks, C.3
Verschuere, T.4
Boon, L.5
Van Gool, S.W.6
-
74
-
-
70350569295
-
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
-
Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med (2009) 15:1170. doi:10.1038/nm.2028
-
(2009)
Nat Med
, vol.15
, pp. 1170
-
-
Ghiringhelli, F.1
Apetoh, L.2
Tesniere, A.3
Aymeric, L.4
Ma, Y.5
Ortiz, C.6
-
75
-
-
61449162046
-
The activation of P2X7 receptor impairs lysosomal functions and stimulates the release of autophagolysosomes in microglial cells
-
Takenouchi T, Nakai M, Iwamaru Y, Sugama S, Tsukimoto M, Fujita M, et al. The activation of P2X7 receptor impairs lysosomal functions and stimulates the release of autophagolysosomes in microglial cells. J Immunol (2009) 182:2051. doi:10.4049/jimmunol.0802577
-
(2009)
J Immunol
, vol.182
, pp. 2051
-
-
Takenouchi, T.1
Nakai, M.2
Iwamaru, Y.3
Sugama, S.4
Tsukimoto, M.5
Fujita, M.6
-
76
-
-
81755173922
-
Constitutive aberrant endogenous interleukin-1 facilitates inflammation and growth in human melanoma
-
Qin Y, Ekmekcioglu S, Liu P, Duncan LM, Lizée G, Poindexter N, et al. Constitutive aberrant endogenous interleukin-1 facilitates inflammation and growth in human melanoma. Mol Cancer Res (2011) 9:1537. doi:10.1158/1541-7786.MCR-11-0279
-
(2011)
Mol Cancer Res
, vol.9
, pp. 1537
-
-
Qin, Y.1
Ekmekcioglu, S.2
Liu, P.3
Duncan, L.M.4
Lizée, G.5
Poindexter, N.6
-
77
-
-
84926473508
-
IL-17-producing gammadelta T cells and neutrophils conspire to promote breast cancer metastasis
-
Coffelt SB, Kersten K, Doornebal CW, Weiden J, Vrijland K, Hau CS, et al. IL-17-producing gammadelta T cells and neutrophils conspire to promote breast cancer metastasis. Nature (2015) 522:345. doi:10.1038/nature14282
-
(2015)
Nature
, vol.522
, pp. 345
-
-
Coffelt, S.B.1
Kersten, K.2
Doornebal, C.W.3
Weiden, J.4
Vrijland, K.5
Hau, C.S.6
-
78
-
-
85016320661
-
Tumor suppression in mice lacking GABARAP, an Atg8/LC3 family member implicated in autophagy, is associated with alterations in cytokine secretion and cell death
-
Salah FS, Ebbinghaus M, Muley VY, Zhou Z, Al-Saadi KR, Pacyna-Gengelbach M, et al. Tumor suppression in mice lacking GABARAP, an Atg8/LC3 family member implicated in autophagy, is associated with alterations in cytokine secretion and cell death. Cell Death Dis (2016) 7:e2205. doi:10.1038/cddis.2016.93
-
(2016)
Cell Death Dis
, vol.7
-
-
Salah, F.S.1
Ebbinghaus, M.2
Muley, V.Y.3
Zhou, Z.4
Al-Saadi, K.R.5
Pacyna-Gengelbach, M.6
-
79
-
-
84896490235
-
The two faces of IL-6 in the tumor microenvironment
-
Fisher DT, Appenheimer MM, Evans SS. The two faces of IL-6 in the tumor microenvironment. Semin Immunol (2014) 26:38. doi:10.1016/j.smim.2014.01.008
-
(2014)
Semin Immunol
, vol.26
, pp. 38
-
-
Fisher, D.T.1
Appenheimer, M.M.2
Evans, S.S.3
-
80
-
-
84923367765
-
Identification of secreted proteins that reflect autophagy dynamics within tumor cells
-
Kraya AA, Piao S, Xu X, Zhang G, Herlyn M, Gimotty P, et al. Identification of secreted proteins that reflect autophagy dynamics within tumor cells. Autophagy (2015) 11:60. doi:10.4161/15548627.2014.984273
-
(2015)
Autophagy
, vol.11
, pp. 60
-
-
Kraya, A.A.1
Piao, S.2
Xu, X.3
Zhang, G.4
Herlyn, M.5
Gimotty, P.6
-
81
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
-
Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol (2010) 11:373. doi:10.1038/ni.1863
-
(2010)
Nat Immunol
, vol.11
, pp. 373
-
-
Kawai, T.1
Akira, S.2
-
82
-
-
84894482142
-
Autophagy facilitates TLR4-and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination
-
Zhan Z, Xie X, Cao H, Zhou X, Zhang XD, Fan H, et al. Autophagy facilitates TLR4-and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination. Autophagy (2014) 10:257. doi:10.4161/auto.27162
-
(2014)
Autophagy
, vol.10
, pp. 257
-
-
Zhan, Z.1
Xie, X.2
Cao, H.3
Zhou, X.4
Zhang, X.D.5
Fan, H.6
-
83
-
-
79952121979
-
Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
-
Iliopoulos D, Hirsch HA, Wang G, Struhl K. Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion. Proc Natl Acad Sci U S A (2011) 108:1397. doi:10.1073/pnas.1018898108
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 1397
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Wang, G.3
Struhl, K.4
-
84
-
-
84928034921
-
Autophagy Supports Breast Cancer Stem Cell Maintenance by Regulating IL6 Secretion
-
Maycotte P, Jones KL, Goodall ML, Thorburn J, Thorburn A. Autophagy Supports Breast Cancer Stem Cell Maintenance by Regulating IL6 Secretion. Mol Cancer Res (2015) 13:651. doi:10.1158/1541-7786.MCR-14-0487
-
(2015)
Mol Cancer Res
, vol.13
, pp. 651
-
-
Maycotte, P.1
Jones, K.L.2
Goodall, M.L.3
Thorburn, J.4
Thorburn, A.5
-
85
-
-
0033927564
-
Assembly of multimeric von Willebrand factor directs sorting of P-selectin
-
Hop C, Guilliatt A, Daly M, de Leeuw HP, Brinkman HJ, Peake IR, et al. Assembly of multimeric von Willebrand factor directs sorting of P-selectin. Arterioscler Thromb Vasc Biol (2000) 20:1763. doi:10.1161/01.ATV.20.7.1763
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 1763
-
-
Hop, C.1
Guilliatt, A.2
Daly, M.3
de Leeuw, H.P.4
Brinkman, H.J.5
Peake, I.R.6
-
86
-
-
77956614939
-
Selectins promote tumor metastasis
-
Laubli H, Borsig L. Selectins promote tumor metastasis. Semin Cancer Biol (2010) 20:169. doi:10.1016/j.semcancer.2010.04.005
-
(2010)
Semin Cancer Biol
, vol.20
, pp. 169
-
-
Laubli, H.1
Borsig, L.2
-
87
-
-
84927575709
-
Canonical autophagy does not contribute to cellular radioresistance
-
Schaaf MB, Jutten B, Keulers TG, Savelkouls KG, Peeters HJ, van den Beucken T, et al. Canonical autophagy does not contribute to cellular radioresistance. Radiother Oncol (2015) 114:406. doi:10.1016/j.radonc.2015.02.019
-
(2015)
Radiother Oncol
, vol.114
, pp. 406
-
-
Schaaf, M.B.1
Jutten, B.2
Keulers, T.G.3
Savelkouls, K.G.4
Peeters, H.J.5
van den Beucken, T.6
-
88
-
-
84924744513
-
Cancer-associated fibroblasts induce high mobility group box 1 and contribute to resistance to doxorubicin in breast cancer cells
-
Amornsupak K, Insawang T, Thuwajit P, O-Charoenrat P, Eccles SA, Thuwajit C. Cancer-associated fibroblasts induce high mobility group box 1 and contribute to resistance to doxorubicin in breast cancer cells. BMC Cancer (2014) 14:955. doi:10.1186/1471-2407-14-955
-
(2014)
BMC Cancer
, vol.14
, pp. 955
-
-
Amornsupak, K.1
Insawang, T.2
Thuwajit, P.3
O-Charoenrat, P.4
Eccles, S.A.5
Thuwajit, C.6
-
89
-
-
77949542302
-
The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival
-
Kang R, Tang D, Schapiro NE, Livesey KM, Farkas A, Loughran P, et al. The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival. Cell Death Differ (2010) 17:666. doi:10.1038/cdd.2009.149
-
(2010)
Cell Death Differ
, vol.17
, pp. 666
-
-
Kang, R.1
Tang, D.2
Schapiro, N.E.3
Livesey, K.M.4
Farkas, A.5
Loughran, P.6
-
90
-
-
84924561380
-
DNA methylation of DKK3 modulates docetaxel chemoresistance in human nonsmall cell lung cancer cell
-
Tao L, Huang G, Chen Y, Chen L. DNA methylation of DKK3 modulates docetaxel chemoresistance in human nonsmall cell lung cancer cell. Cancer Biother Radiopharm (2015) 30:100. doi:10.1089/cbr.2014.1797
-
(2015)
Cancer Biother Radiopharm
, vol.30
, pp. 100
-
-
Tao, L.1
Huang, G.2
Chen, Y.3
Chen, L.4
-
91
-
-
84937516444
-
The role of Dickkopf-3 overexpression in esophageal adenocarcinoma
-
Wang Z, Lin L, Thomas DG, Nadal E, Chang AC, Beer DG, et al. The role of Dickkopf-3 overexpression in esophageal adenocarcinoma. J Thorac Cardiovasc Surg (2015) 150:377. doi:10.1016/j.jtcvs.2015.05.006
-
(2015)
J Thorac Cardiovasc Surg
, vol.150
, pp. 377
-
-
Wang, Z.1
Lin, L.2
Thomas, D.G.3
Nadal, E.4
Chang, A.C.5
Beer, D.G.6
-
92
-
-
42349109493
-
GABA(A) receptor trafficking and its role in the dynamic modulation of neuronal inhibition
-
Jacob TC, Moss SJ, Jurd R. GABA(A) receptor trafficking and its role in the dynamic modulation of neuronal inhibition. Nat Rev Neurosci (2008) 9:331. doi:10.1038/nrn2370
-
(2008)
Nat Rev Neurosci
, vol.9
, pp. 331
-
-
Jacob, T.C.1
Moss, S.J.2
Jurd, R.3
-
93
-
-
79955389758
-
Effects of C-terminal modifications of GEC1 protein and gamma-aminobutyric acid type A (GABA(A)) receptor-associated protein (GABARAP), two microtubule-associated proteins, on kappa opioid receptor expression
-
Chen C, Wang Y, Huang P, Liu-Chen LY. Effects of C-terminal modifications of GEC1 protein and gamma-aminobutyric acid type A (GABA(A)) receptor-associated protein (GABARAP), two microtubule-associated proteins, on kappa opioid receptor expression. J Biol Chem (2011) 286:15106. doi:10.1074/jbc.M111.230896
-
(2011)
J Biol Chem
, vol.286
, pp. 15106
-
-
Chen, C.1
Wang, Y.2
Huang, P.3
Liu-Chen, L.Y.4
-
94
-
-
77953530119
-
GABAA receptor associated protein (GABARAP) modulates TRPV1 expression and channel function and desensitization
-
Laínez S, Valente P, Ontoria-Oviedo I, Estévez-Herrera J, Camprubí-Robles M, Ferrer-Montiel A, et al. GABAA receptor associated protein (GABARAP) modulates TRPV1 expression and channel function and desensitization. FASEB J (2010) 24:1958. doi:10.1096/fj.09-151472
-
(2010)
FASEB J
, vol.24
, pp. 1958
-
-
Laínez, S.1
Valente, P.2
Ontoria-Oviedo, I.3
Estévez-Herrera, J.4
Camprubí-Robles, M.5
Ferrer-Montiel, A.6
-
95
-
-
48249104676
-
The trafficking protein GABARAP binds to and enhances plasma membrane expression and function of the angiotensin II type 1 receptor
-
Cook JL, Re RN, deHaro DL, Abadie JM, Peters M, Alam J. The trafficking protein GABARAP binds to and enhances plasma membrane expression and function of the angiotensin II type 1 receptor. Circ Res (2008) 102:1539. doi:10.1161/CIRCRESAHA.108.176594
-
(2008)
Circ Res
, vol.102
, pp. 1539
-
-
Cook, J.L.1
Re, R.N.2
deHaro, D.L.3
Abadie, J.M.4
Peters, M.5
Alam, J.6
-
96
-
-
71349086066
-
C-terminal processing of GABARAP is not required for trafficking of the angiotensin II type 1A receptor
-
Alam J, Deharo D, Redding KM, Re RN, Cook JL. C-terminal processing of GABARAP is not required for trafficking of the angiotensin II type 1A receptor. Regul Pept (2010) 159:78. doi:10.1016/j.regpep.2009.09.002
-
(2010)
Regul Pept
, vol.159
, pp. 78
-
-
Alam, J.1
Deharo, D.2
Redding, K.M.3
Re, R.N.4
Cook, J.L.5
-
97
-
-
70249121467
-
The deletion mutant EGFRvIII significantly contributes to stress resistance typical for the tumour microenvironment
-
Theys J, Jutten B, Dubois L, Rouschop KM, Chiu RK, Li Y, et al. The deletion mutant EGFRvIII significantly contributes to stress resistance typical for the tumour microenvironment. Radiother Oncol (2009) 92:399. doi:10.1016/j.radonc.2009.06.017
-
(2009)
Radiother Oncol
, vol.92
, pp. 399
-
-
Theys, J.1
Jutten, B.2
Dubois, L.3
Rouschop, K.M.4
Chiu, R.K.5
Li, Y.6
-
98
-
-
84892589371
-
EGFR signaling and autophagy dependence for growth, survival, and therapy resistance
-
Jutten B, Rouschop KM. EGFR signaling and autophagy dependence for growth, survival, and therapy resistance. Cell Cycle (2014) 13:42. doi:10.4161/cc.27518
-
(2014)
Cell Cycle
, vol.13
, pp. 42
-
-
Jutten, B.1
Rouschop, K.M.2
-
99
-
-
84906877052
-
GABA(A) receptor pi (GABRP) stimulates basal-like breast cancer cell migration through activation of extracellular-regulated kinase 1/2 (ERK1/2)
-
Sizemore GM, Sizemore ST, Seachrist DD, Keri RA. GABA(A) receptor pi (GABRP) stimulates basal-like breast cancer cell migration through activation of extracellular-regulated kinase 1/2 (ERK1/2). J Biol Chem (2014) 289:24102. doi:10.1074/jbc.M114.593582
-
(2014)
J Biol Chem
, vol.289
, pp. 24102
-
-
Sizemore, G.M.1
Sizemore, S.T.2
Seachrist, D.D.3
Keri, R.A.4
-
100
-
-
84863090722
-
GABA stimulates human hepatocellular carcinoma growth through overexpressed GABAA receptor theta subunit
-
Li YH, Liu Y, Li YD, Liu YH, Li F, Ju Q, et al. GABA stimulates human hepatocellular carcinoma growth through overexpressed GABAA receptor theta subunit. World J Gastroenterol (2012) 18:2704. doi:10.3748/wjg.v18.i21.2704
-
(2012)
World J Gastroenterol
, vol.18
, pp. 2704
-
-
Li, Y.H.1
Liu, Y.2
Li, Y.D.3
Liu, Y.H.4
Li, F.5
Ju, Q.6
-
101
-
-
63449136465
-
Gamma-aminobutyric acid promotes human hepatocellular carcinoma growth through overexpressed gamma-aminobutyric acid A receptor alpha 3 subunit
-
Liu Y, Li YH, Guo FJ, Wang JJ, Sun RL, Hu JY, et al. Gamma-aminobutyric acid promotes human hepatocellular carcinoma growth through overexpressed gamma-aminobutyric acid A receptor alpha 3 subunit. World J Gastroenterol (2008) 14:7175. doi:10.3748/wjg.14.7175
-
(2008)
World J Gastroenterol
, vol.14
, pp. 7175
-
-
Liu, Y.1
Li, Y.H.2
Guo, F.J.3
Wang, J.J.4
Sun, R.L.5
Hu, J.Y.6
-
102
-
-
84861789393
-
Beta-adrenergic signaling in the development and progression of pulmonary and pancreatic adenocarcinoma
-
Schuller HM, Al-Wadei HA. Beta-adrenergic signaling in the development and progression of pulmonary and pancreatic adenocarcinoma. Curr Cancer Ther Rev (2012) 8:116. doi:10.2174/157339412800675351
-
(2012)
Curr Cancer Ther Rev
, vol.8
, pp. 116
-
-
Schuller, H.M.1
Al-Wadei, H.A.2
-
103
-
-
35448969671
-
Gamma-aminobutyric acid (GABA) stimulates pancreatic cancer growth through overexpressing GABAA receptor pi subunit
-
Takehara A, Hosokawa M, Eguchi H, Ohigashi H, Ishikawa O, Nakamura Y, et al. Gamma-aminobutyric acid (GABA) stimulates pancreatic cancer growth through overexpressing GABAA receptor pi subunit. Cancer Res (2007) 67:9704. doi:10.1158/0008-5472.CAN-07-2099
-
(2007)
Cancer Res
, vol.67
, pp. 9704
-
-
Takehara, A.1
Hosokawa, M.2
Eguchi, H.3
Ohigashi, H.4
Ishikawa, O.5
Nakamura, Y.6
-
104
-
-
84891096632
-
Linking gamma-aminobutyric acid A receptor to epidermal growth factor receptor pathways activation in human prostate cancer
-
Wu W, Yang Q, Fung KM, Humphreys MR, Brame LS, Cao A, et al. Linking gamma-aminobutyric acid A receptor to epidermal growth factor receptor pathways activation in human prostate cancer. Mol Cell Endocrinol (2014) 383:69. doi:10.1016/j.mce.2013.11.017
-
(2014)
Mol Cell Endocrinol
, vol.383
, pp. 69
-
-
Wu, W.1
Yang, Q.2
Fung, K.M.3
Humphreys, M.R.4
Brame, L.S.5
Cao, A.6
-
105
-
-
28744440846
-
GABARAP is not essential for GABA receptor targeting to the synapse
-
O'Sullivan GA, Kneussel M, Elazar Z, Betz H. GABARAP is not essential for GABA receptor targeting to the synapse. Eur J Neurosci (2005) 22:2644. doi:10.1111/j.1460-9568.2005.04448.x
-
(2005)
Eur J Neurosci
, vol.22
, pp. 2644
-
-
O'Sullivan, G.A.1
Kneussel, M.2
Elazar, Z.3
Betz, H.4
-
106
-
-
84884410674
-
Inhibition of tumor promoting signals by activation of SSTR2 and opioid receptors in human breast cancer cells
-
Kharmate G, Rajput PS, Lin YC, Kumar U. Inhibition of tumor promoting signals by activation of SSTR2 and opioid receptors in human breast cancer cells. Cancer Cell Int (2013) 13:93. doi:10.1186/1475-2867-13-93
-
(2013)
Cancer Cell Int
, vol.13
, pp. 93
-
-
Kharmate, G.1
Rajput, P.S.2
Lin, Y.C.3
Kumar, U.4
-
107
-
-
0033134813
-
Opioid agonists modify breast cancer cell proliferation by blocking cells to the G2/M phase of the cycle: involvement of cytoskeletal elements
-
Panagiotou S, Bakogeorgou E, Papakonstanti E, Hatzoglou A, Wallet F, Dussert C, et al. Opioid agonists modify breast cancer cell proliferation by blocking cells to the G2/M phase of the cycle: involvement of cytoskeletal elements. J Cell Biochem (1999) 73:204. doi:10.1002/(SICI)1097-4644(19990501)73:2<204::AID-JCB6>3.0.CO;2-V
-
(1999)
J Cell Biochem
, vol.73
, pp. 204
-
-
Panagiotou, S.1
Bakogeorgou, E.2
Papakonstanti, E.3
Hatzoglou, A.4
Wallet, F.5
Dussert, C.6
|