IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis

Nature

Volumn 522, Issue 7556, 2015, Pages 345-348

  Coffelt, Seth B ^a   Kersten, Kelly ^a   Doornebal, Chris W ^a   Weiden, Jorieke ^a   Vrijland, Kim ^a   Hau, Cheei Sing ^a   Verstegen, Niels J M ^a   Ciampricotti, Metamia ^a   Hawinkels, Lukas J A C ^b   Jonkers, Jos ^a   De Visser, Karin E ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 12P40; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; TRANSFORMING GROWTH FACTOR BETA1;

CANCER; CAUSE OF DEATH; CELLS AND CELL COMPONENTS; GENE EXPRESSION; IMMUNE SYSTEM; PROTEIN; RODENT; TUMOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CANCER METASTASIS; BREAST METASTASIS; CANCER GROWTH; CELL EXPANSION; CELL PROLIFERATION ASSAY; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DOWN REGULATION; EX VIVO STUDY; FEMALE; FLOW CYTOMETRY; GAMMA DELTA T LYMPHOCYTE; IMMUNOHISTOCHEMISTRY; LUNG METASTASIS; LYMPH NODE METASTASIS; MOUSE; NEUTROPHIL; NEUTROPHIL COUNT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION; UPREGULATION; ANIMAL; BIOSYNTHESIS; BREAST TUMOR; CD8+ T LYMPHOCYTE; CYTOLOGY; DISEASE MODEL; IMMUNOLOGY; LUNG; LUNG TUMOR; LYMPHOCYTE ACTIVATION; METABOLISM; METASTASIS; PATHOLOGY; SECONDARY; T LYMPHOCYTE SUBPOPULATION; TUMOR MICROENVIRONMENT;

MUS;

ANIMALS; BREAST NEOPLASMS; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; FEMALE; GRANULOCYTE COLONY-STIMULATING FACTOR; INTERLEUKIN-17; INTERLEUKIN-1BETA; LUNG; LUNG NEOPLASMS; LYMPHATIC METASTASIS; LYMPHOCYTE ACTIVATION; MICE; NEOPLASM METASTASIS; NEUTROPHILS; PHENOTYPE; T-LYMPHOCYTE SUBSETS; TUMOR MICROENVIRONMENT;

EID: 84926473508     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14282     Document Type: Article

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